Philip A Cole

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 39

Top Topics

Histone Deacetylase

Cell Proliferation

Structural Basis

Peripheral Nerve

Top Venues

Journal of the American Chemical Society

bioRxiv : the preprint server for biology

Cancer research communications

This page only lists publications with an associated author ORCID identifier.

Publications

Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT Regulates SOX10 Stability and Function in Human Melanoma. Cancer research communications 4 (8) (2024)
Hanjie Jiang, Bryant D Miller, Thibault Viennet, HyoJeon Kim, Kwangwoon Lee, Haribabu Arthanari, Philip A Cole
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms. Nature chemistry (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. bioRxiv : the preprint server for biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. Cancer research communications (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. Cancer research communications (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. bioRxiv : the preprint server for biology (2024)
Imad Soukar, Robert Fisher, Sanjana Bhagavatula, Marianne Collard, Philip A Cole, Rhoda M Alani
The CoREST complex is a therapeutic vulnerability in malignant peripheral nerve sheath tumors. bioRxiv : the preprint server for biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. bioRxiv : the preprint server for biology (2024)
Kwangwoon Lee, Marco Barone, Amanda L Waterbury, Hanjie Jiang, Eunju Nam, Sarah E DuBois-Coyne, Samuel D Whedon, Zhipeng A Wang, Jonatan Caroli, Katherine Neal, Brian Ibeabuchi, Zuzer Dhoondia, Mitzi I Kuroda, Brian B Liau, Samuel Beck, Andrea Mattevi, Philip A Cole
Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1. Nature chemical biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT Regulates SOX10 Stability and Function in Human Melanoma. Cancer research communications 4 (8) (2024)
Megan Jin Rae Yeo, Olivia Zhang, Xiaowen Xie, Eunju Nam, Neil Connor Payne, Pallavi M Gosavi, Hui Si Kwok, Irtiza Iram, Ceejay Lee, Jiaming Li, Nicholas J Chen, Hanjie Jiang, Zhipeng A Wang, Kwangwoon Lee, Haibin Mao, Stefan Andrew Harry, Idris A Barakat, Mariko Takahashi, Amanda L Waterbury, Marco Barone, Andrea Mattevi, Liron Bar-Peled, Philip A Cole, Ralph Mazitschek, Brian B Liau, Ning Zheng
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. bioRxiv : the preprint server for biology (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT Regulates SOX10 Stability and Function in Human Melanoma. Cancer research communications 4 (8) (2024)
Aaron R Waddell, Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park, Marianne Collard, Philip A Cole, Rhoda M Alani
p300 KAT regulates SOX10 stability and function in human melanoma. bioRxiv : the preprint server for biology (2024)
Xiaowen Xie, Olivia Zhang, Megan Jin Rae Yeo, Ceejay Lee, Stefan Andrew Harry, Leena Paul, Yiran Li, Neil Connor Payne, Eunju Nam, Hui Si Kwok, Hanjie Jiang, Haibin Mao, Jennifer L Hadley, Hong Lin, Melissa Batts, Pallavi M Gosavi, Vincenzo D'Angiolella, Philip A Cole, Ralph Mazitschek, Paul A Northcott, Ning Zheng, Brian B Liau
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. bioRxiv : the preprint server for biology (2024)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Reina Iwase, Daniel R Dempsey, Samuel D Whedon, Hanjie Jiang, Brad A Palanski, Bedphiny Deng, Philip A Cole
Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination. Journal of the American Chemical Society (2023)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Zhipeng A Wang, Jonathan W Markert, Samuel D Whedon, Maheeshi Yapa Abeywardana, Kwangwoon Lee, Hanjie Jiang, Carolay Suarez, Hening Lin, Lucas Farnung, Philip A Cole
Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. Journal of the American Chemical Society (2023)
Reina Iwase, Daniel R Dempsey, Samuel D Whedon, Hanjie Jiang, Brad A Palanski, Bedphiny Deng, Philip A Cole
Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination. Journal of the American Chemical Society 145 (11) (2023)
Katharine M Wright, Hanjie Jiang, Wendy Xia, Michael B Murphy, Tatiana N Boronina, Justin N Nwafor, HyoJeon Kim, Akunna M Iheanacho, P Aitana Azurmendi, Robert N Cole, Philip A Cole, Sandra B Gabelli
The C-Terminal of Na V 1.7 Is Ubiquitinated by NEDD4L. ACS bio & med chem Au 3 (6) (2023)
Katharine M Wright, Hanjie Jiang, Wendy Xia, Michael B Murphy, Tatiana N Boronina, Justin N Nwafor, HyoJeon Kim, Akunna M Iheanacho, P Aitana Azurmendi, Robert N Cole, Philip A Cole, Sandra B Gabelli
The C-Terminal of Na V 1.7 Is Ubiquitinated by NEDD4L. ACS bio & med chem Au 3 (6) (2023)
Jayme L Dahlin, Bruce K Hua, Beth E Zucconi, Shawn D Nelson, Shantanu Singh, Anne E Carpenter, Jonathan H Shrimp, Evelyne Lima-Fernandes, Mathias J Wawer, Lawrence P W Chung, Ayushi Agrawal, Mary O'Reilly, Dalia Barsyte-Lovejoy, Magdalena Szewczyk, Fengling Li, Parnian Lak, Matthew E Cuellar, Philip A Cole, Jordan L Meier, Tim Thomas, Jonathan B Baell, Peter J Brown, Michael A Walters, Paul A Clemons, Stuart L Schreiber, Bridget K Wagner
Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nature communications 14 (1) (2023)
Arian Mansur, Remi Joseph, Euri Kim, Pierre M Jean Beltran, Namrata D Udeshi, Cadence Pearce, Hanjie Jiang, Reina Iwase, Miroslav P Milev, Hashem A Almousa, Elyshia McNamara, Jeffrey Widrick, Claudio Perez, Gianina Ravenscroft, Michael Sacher, Philip A Cole, Steven A Carr, Vandana A Gupta
Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset. eLife 12 (2023)
Reina Iwase, Daniel R Dempsey, Samuel D Whedon, Hanjie Jiang, Brad A Palanski, Bedphiny Deng, Philip A Cole
Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination. Journal of the American Chemical Society 145 (11) (2023)
Hwan Bae, Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta Salguero, Michael J Eck, Haribabu Arthanari, Philip A Cole
PH domain-mediated autoinhibition and oncogenic activation of Akt. eLife 11 (2022)
Zhipeng A Wang, Samuel D Whedon, Mingxuan Wu, Siyu Wang, Edward A Brown, Ananya Anmangandla, Liam Regan, Kwangwoon Lee, Jianfeng Du, Jun Young Hong, Louise Fairall, Taylor Kay, Hening Lin, Yingming Zhao, John W R Schwabe, Philip A Cole
Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase. Journal of the American Chemical Society 144 (8) (2022)
Hanjie Jiang, Daniel R Dempsey, Philip A Cole
Ubiquitin Ligase Activities of WWP1 Germline Variants K740N and N745S. Biochemistry 60 (5) (2021)
Daniel R Dempsey, Thibault Viennet, Reina Iwase, Eunyoung Park, Stephanie Henriquez, Zan Chen, Jeliazko R Jeliazkov, Brad A Palanski, Kim L Phan, Paul Coote, Jeffrey J Gray, Michael J Eck, Sandra B Gabelli, Haribabu Arthanari, Philip A Cole
The structural basis of PTEN regulation by multi-site phosphorylation. Nature structural & molecular biology 28 (10) (2021)
Antonieta L Salguero, Maggie Chen, Aaron T Balana, Nam Chu, Hanjie Jiang, Brad A Palanski, Hwan Bae, Katharine M Wright, Sara Nathan, Heng Zhu, Sandra B Gabelli, Matthew R Pratt, Philip A Cole
Multifaceted Regulation of Akt by Diverse C-Terminal Post-translational Modifications. ACS chemical biology 17 (1) (2021)
Zhipeng A Wang, Christopher J Millard, Chia-Liang Lin, Jennifer E Gurnett, Mingxuan Wu, Kwangwoon Lee, Louise Fairall, John W R Schwabe, Philip A Cole
Diverse nucleosome Site-Selectivity among histone deacetylase complexes. eLife 9 (2020)
Nam Chu, Thibault Viennet, Hwan Bae, Antonieta Salguero, Andras Boeszoermenyi, Haribabu Arthanari, Philip A Cole
The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling. eLife 9 (2020)
Samuel H Henager, Stephanie Henriquez, Daniel R Dempsey, Philip A Cole
Analysis of Site-Specific Phosphorylation of PTEN by Using Enzyme-Catalyzed Expressed Protein Ligation. Chembiochem : a European journal of chemical biology 21 (1-2) (2019)
Beth E Zucconi, Jessica L Makofske, David J Meyers, Yousang Hwang, Mingxuan Wu, Mitzi I Kuroda, Philip A Cole
Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP. Biochemistry 58 (16) (2019)
Daniel R Dempsey, Hanjie Jiang, Jay H Kalin, Zan Chen, Philip A Cole
Site-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase Mechanisms. Journal of the American Chemical Society 140 (30) (2018)
Mingxuan Wu, Dawn Hayward, Jay H Kalin, Yun Song, John W R Schwabe, Philip A Cole
Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. eLife 7 (2018)
Shridhar Bhat, Yousang Hwang, Matthew D Gibson, Michael T Morgan, Sean D Taverna, Yingming Zhao, Cynthia Wolberger, Michael G Poirier, Philip A Cole
Hydrazide Mimics for Protein Lysine Acylation To Assess Nucleosome Dynamics and Deubiquitinase Action. Journal of the American Chemical Society 140 (30) (2018)