Brian C Smith

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

ACS chemical biology

Journal of medicinal chemistry

The Journal of biological chemistry

Molecules (Basel, Switzerland)

Medical College of Wisconsin

University of Wisconsin Madison (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Medical College of Wisconsin Jun 01 2014

United States

Assistant Professor :: Biochemistry

Scripps Research Institute Jan 01 2012 - May 31 2014

United States

Postdoctoral Research Associate :: Chemistry

University of California Berkeley Sep 01 2009 - Dec 31 2011

United States

Postdoctoral Research Associate :: QB3 Institute

Education History

University of Wisconsin Madison

United States

PHD :: Chemistry

University of Illinois at Urbana-Champaign

United States

BSC :: Chemistry

Publications

Rachel A Jones Lipinski, Jennifer S Stancill, Raymundo Nuñez, Sarah L Wynia-Smith, Daniel J Sprague, Joshua A Nord, Amir Bird, John A Corbett, Brian C Smith
Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. American journal of physiology. Regulatory, integrative and comparative physiology 326 (6) (2024)
Balaram Pradhan, Matteo Pavan, Courtney L Fisher, Veronica Salmaso, Tina C Wan, Robert F Keyes, Noah Rollison, R Rama Suresh, T Santhosh Kumar, Zhan-Guo Gao, Brian C Smith, John A Auchampach, Kenneth A Jacobson
Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). Journal of medicinal chemistry 67 (14) (2024)
Karina L Bursch, Christopher J Goetz, Brian C Smith
Current Trends in Sirtuin Activator and Inhibitor Development. Molecules (Basel, Switzerland) 29 (5) (2024)
Rachel A Jones Lipinski, Jennifer S Stancill, Raymundo Nuñez, Sarah L Wynia-Smith, Daniel J Sprague, Joshua A Nord, Amir Bird, John A Corbett, Brian C Smith
Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types. American journal of physiology. Regulatory, integrative and comparative physiology 326 (6) (2024)
Karina L Bursch, Christopher J Goetz, Brian C Smith
Current Trends in Sirtuin Activator and Inhibitor Development. Molecules (Basel, Switzerland) 29 (5) (2024)
Kelsey Bohl, Sarah L Wynia-Smith, Rachel A Jones Lipinski, Brian C Smith
Inhibition of Sirtuin Deacylase Activity by Peroxynitrite. Biochemistry (2024)
Balaram Pradhan, Matteo Pavan, Courtney L Fisher, Veronica Salmaso, Tina C Wan, Robert F Keyes, Noah Rollison, R Rama Suresh, T Santhosh Kumar, Zhan-Guo Gao, Brian C Smith, John A Auchampach, Kenneth A Jacobson
Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). Journal of medicinal chemistry 67 (14) (2024)
Karina L Bursch, Christopher J Goetz, Brian C Smith
Current Trends in Sirtuin Activator and Inhibitor Development. Molecules (Basel, Switzerland) 29 (5) (2024)
Balaram Pradhan, Matteo Pavan, Courtney L Fisher, Veronica Salmaso, Tina C Wan, Robert F Keyes, Noah Rollison, R Rama Suresh, T Santhosh Kumar, Zhan-Guo Gao, Brian C Smith, John A Auchampach, Kenneth A Jacobson
Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). Journal of medicinal chemistry 67 (14) (2024)
Balaram Pradhan, Matteo Pavan, Courtney L Fisher, Veronica Salmaso, Tina C Wan, Robert F Keyes, Noah Rollison, R Rama Suresh, T Santhosh Kumar, Zhan-Guo Gao, Brian C Smith, John A Auchampach, Kenneth A Jacobson
Lipid Trolling to Optimize A 3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). Journal of medicinal chemistry (2024)
Jue Zhang, Jackie Chang, Vaya Chen, Mirza Ahmar Beg, Wenxin Huang, Lance Vick, Yaxin Wang, Heng Zhang, Erin Yttre, Ankan Gupta, Mark Castleberry, Ziyu Zhang, Wen Dai, Shan Song, Jieqing Zhu, Moua Yang, Ashley Kaye Brown, Zhen Xu, Yan-Qing Ma, Brian C Smith, Jacek Zielonka, James G Traylor, Cyrine Ben Dhaou, A Wayne Orr, Weiguo Cui, Ze Zheng, Yiliang Chen
Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway. bioRxiv : the preprint server for biology (2024)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Sandra C Ordonez-Rubiano, Chad A Maschinot, Sijie Wang, Surbhi Sood, Luisa F Baracaldo-Lancheros, Brayden P Strohmier, Alexander J McQuade, Brian C Smith, Emily C Dykhuizen
Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. Journal of medicinal chemistry (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology 19 (1) (2023)
Julia A Falco, Sarah L Wynia-Smith, James McCoy, Brian C Smith, Eranthie Weerapana
Identification of Protein Targets of S -Nitroso-Coenzyme A-Mediated S -Nitrosation Using Chemoproteomics. ACS chemical biology (2023)
Young-In Chi, Salomão D Jorge, Davin R Jensen, Brian C Smith, Brian F Volkman, Angela J Mathison, Gwen Lomberk, Michael T Zimmermann, Raul Urrutia
A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1. bioRxiv : the preprint server for biology (2023)
Shifali Shishodia, Raymundo Nuñez, Brayden P Strohmier, Karina L Bursch, Christopher J Goetz, Michael D Olp, Davin R Jensen, Tyler G Fenske, Sandra C Ordonez-Rubiano, Maya E Blau, Mallory K Roach, Francis C Peterson, Brian F Volkman, Emily C Dykhuizen, Brian C Smith
Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. Journal of medicinal chemistry 65 (20) (2022)
Courtney L Fisher, Lucas B Fallot, Tina C Wan, Robert F Keyes, R Rama Suresh, Amy C Rothwell, Zhan-Guo Gao, John D McCorvy, Brian C Smith, Kenneth A Jacobson, John A Auchampach
Characterization of Dual-Acting A 3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα i3 and Gα oA Isoprotein Activation. ACS pharmacology & translational science 5 (8) (2022)
Xinrui Wang, Tina C Wan, Katherine R Kulik, Amelia Lauth, Brian C Smith, John W Lough, John A Auchampach
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury. Disease models & mechanisms 16 (5) (2022)
Timothy J Stodola, Young-In Chi, Thiago M De Assuncao, Elise N Leverence, Swarnendu Tripathi, Nikita R Dsouza, Angela J Mathison, Brian F Volkman, Brian C Smith, Gwen Lomberk, Michael T Zimmermann, Raul A Urrutia
Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis. Proteins (2021)
Daniel J Sprague, Anthony E Getschman, Tyler G Fenske, Brian F Volkman, Brian C Smith
Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12. ACS medicinal chemistry letters 12 (11) (2021)
Michael D Olp, Daniel J Sprague, Christopher J Goetz, Stefan G Kathman, Sarah L Wynia-Smith, Shifali Shishodia, Steven B Summers, Ziyang Xu, Alexander V Statsyuk, Brian C Smith
Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites. ACS chemical biology 15 (4) (2020)
Arun Kapoor, Ayan K Ghosh, Michael Forman, Xin Hu, Wenjuan Ye, Noel Southall, Juan Marugan, Robert F Keyes, Brian C Smith, David J Meyers, Marc Ferrer, Ravit Arav-Boger
Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus. Journal of medicinal chemistry 63 (8) (2020)
Kelsey S Kalous, Sarah L Wynia-Smith, Steven B Summers, Brian C Smith
Human sirtuins are differentially sensitive to inhibition by nitrosating agents and other cysteine oxidants. The Journal of biological chemistry 295 (25) (2020)
Joel J Bruegger, Brian C Smith, Sarah L Wynia-Smith, Michael A Marletta
Comparative and integrative metabolomics reveal that S-nitrosation inhibits physiologically relevant metabolic enzymes. The Journal of biological chemistry 293 (17) (2018)
Michael D Olp, Nan Zhu, Brian C Smith
Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4. Biochemistry 56 (41) (2017)
Kelsey S Kalous, Sarah L Wynia-Smith, Michael D Olp, Brian C Smith
Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by Cysteine S-Nitrosation. The Journal of biological chemistry 291 (49) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Brian C Smith