Brian K Coombes

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 16

Top Venues

Infection and immunity

PLoS pathogens

Nature communications

Nature chemical biology

McMaster University

McMaster University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

McMaster University Jul 01 2016

Canada

Professor and University Scholar :: Biochemistry and Biomedical Sciences

McMaster University Jul 01 2010

Canada

Associate Chair :: Biochemistry & Biomedical Sciences

McMaster University Jul 01 2010

Canada

Assistant Dean, Biochemistry Graduate Program :: Faculty of Health Sciences Graduate Program

McMaster University Aug 01 2011 - Jul 01 2016

Canada

Associate Professor :: Biochemistry & Biomedical Sciences

McMaster University Feb 01 2006 - Jul 01 2011

Canada

Assistant Professor :: Biochemistry & Biomedical Sciences

Public Health Agency of Canada Feb 01 2006 - Mar 01 2009

Canada

Scientist :: Laboratory for Foodborne Zoonoses

University of British Columbia Sep 01 2002 - Jan 01 2006

Canada

Postdoctoral Fellow :: Michael Smith Laboratories

Education History

McMaster University Sep 01 1997 - Jul 01 2002

Canada

PHD :: Medical Sciences

McMaster University Sep 01 1993 - Apr 01 1997

Canada

BSC :: Biochemistry and Biomedical Sciences

Publications

Caressa N Tsai, Marie-Ange Massicotte, Craig R MacNair, Jordyn N Perry, Eric D Brown, Brian K Coombes
Screening under infection-relevant conditions reveals chemical sensitivity in multidrug resistant invasive non-typhoidal Salmonella (iNTS). RSC chemical biology 4 (8) (2023)
Megan T Zangara, Lena Darwish, Brian K Coombes
Characterizing the Pathogenic Potential of Crohn's Disease-Associated Adherent-Invasive Escherichia coli. EcoSal Plus (2023)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Correction for Popov et al., "Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice". Infection and immunity (2023)
Gary Liu, Denise B Catacutan, Khushi Rathod, Kyle Swanson, Wengong Jin, Jody C Mohammed, Anush Chiappino-Pepe, Saad A Syed, Meghan Fragis, Kenneth Rachwalski, Jakob Magolan, Michael G Surette, Brian K Coombes, Tommi S Jaakkola, Regina Barzilay, James J Collins, Jonathan M Stokes
Deep learning-guided discovery of an antibiotic targeting Acinetobacter baumannii. Nature chemical biology (2023)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Wael Elhenawy, Sarah Hordienko, Steven Gould, Alexander M Oberc, Caressa N Tsai, Troy P Hubbard, Matthew Kaden Waldor, Brian K Coombes
High-throughput fitness screening and transcriptomics identify a role for a type IV secretion system in the pathogenesis of Crohn's disease-associated Escherichia coli. Nature communications 12 (1) (2021)
Christopher R Shaler, Alexandra A Parco, Wael Elhenawy, Jasmeen Dourka, Jennifer Jury, Elena F Verdu, Brian K Coombes
Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts. Nature communications 12 (1) (2021)
N Y Elizabeth Chau, Shehryar Ahmad, John C Whitney, Brian K Coombes
Emerging and divergent roles of pyrophosphorylated nucleotides in bacterial physiology and pathogenesis. PLoS pathogens 17 (5) (2021)
N Y Elizabeth Chau, Deyanira Pérez-Morales, Wael Elhenawy, Víctor H Bustamante, Yong E Zhang, Brian K Coombes
(p)ppGpp-Dependent Regulation of the Nucleotide Hydrolase PpnN Confers Complement Resistance in Salmonella enterica Serovar Typhimurium. Infection and immunity 89 (2) (2021)
Mark S Ladinsky, Leandro P Araujo, Xiao Zhang, John Veltri, Marta Galán-Díez, Salima Soualhi, Carolyn Lee, Koichiro Irie, Elisha Y Pinker, Seiko Narushima, Sheila Bandyopadhyay, Manabu Nagayama, Wael Elhenawy, Brian K Coombes, Ronaldo P Ferraris, Kenya Honda, Iliyan D Iliev, Nan Gao, Pamela J Bjorkman, Ivaylo I Ivanov
Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis. Science (New York, N.Y.) 363 (6431) (2019)
Dustin J Little, Brian K Coombes
Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli. PLoS pathogens 14 (8) (2018)
Cherrie L Small, Lydia Xing, Joseph B McPhee, Hong T Law, Brian K Coombes
Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period. PLoS pathogens 12 (10) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Brian K Coombes