Alexei Savchenko

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 54

Top Venues

Protein science : a publication of the Protein Society

mBio

Infection and immunity

Applied and environmental microbiology

University of Calgary

Université de Nantes (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Calgary Sep 01 2016

Canada

Associate Professor :: Microbiology, Immunology and Infectious Diseases

University of Toronto Jun 01 2011

Canada

Associate Professor :: Chemical Engineering and Applied Chemistry

Education History

Université de Nantes Sep 01 1992 - Nov 01 1996

France

PHD

Publications

Tiffany V Penner, Neil Lorente Cobo, Deepak T Patel, Dhruvin H Patel, Alexei Savchenko, Ann Karen C Brassinga, Gerd Prehna
Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein science : a publication of the Protein Society 33 (3) (2024)
Lukas Syriste, Deepak T Patel, Peter J Stogios, Tatiana Skarina, Dhruvin Patel, Alexei Savchenko
An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation. mBio 15 (3) (2024)
Anna N Khusnutdinova, Hai Tran, Saloni Devlekar, Marco A Distaso, Ilya V Kublanov, Tatiana Skarina, Peter Stogios, Alexei Savchenko, Manuel Ferrer, Olga V Golyshina, Alexander F Yakunin, Peter N Golyshin
Moderately thermostable GH1 β-glucosidases from hyperacidophilic archaeon Cuniculiplasma divulgatum S5. FEMS microbiology ecology (2024)
Cameron Semper, Nobuhiko Watanabe, Elina Karimullina, Deepak T Patel, Rosa Di Leo, Mildred Castellanos, Dhruvin H Patel, George Chaconas, Alexei Savchenko
Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain. Nucleic acids research 52 (14) (2024)
Chester Pham, Peter J Stogios, Alexei Savchenko, Radhakrishnan Mahadevan
Design and Characterization of a Generalist Biosensor for Indole Derivatives. ACS synthetic biology (2024)
Tiffany V Penner, Neil Lorente Cobo, Deepak T Patel, Dhruvin H Patel, Alexei Savchenko, Ann Karen C Brassinga, Gerd Prehna
Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein science : a publication of the Protein Society 33 (3) (2024)
Monica Rosas-Lemus, George Minasov, Joseph S Brunzelle, Taha Y Taha, Sofia Lemak, Shaohui Yin, Ludmilla Shuvalova, Julia Rosecrans, Kanika Khanna, H Steven Seifert, Alexei Savchenko, Peter J Stogios, Melanie M Ott, Karla J F Satchell
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains. bioRxiv : the preprint server for biology (2024)
Lukas Syriste, Deepak T Patel, Peter J Stogios, Tatiana Skarina, Dhruvin Patel, Alexei Savchenko
An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation. mBio 15 (3) (2024)
Chester Pham, Mohamed A Nasr, Tatiana Skarina, Rosa Di Leo, David H Kwan, Vincent J J Martin, Peter J Stogios, Radhakrishnan Mahadevan, Alexei Savchenko
Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors. The FEBS journal 291 (15) (2024)
Malene L Urbanus, Thomas M Zheng, Anna N Khusnutdinova, Doreen Banh, Harley O'Connor Mount, Alind Gupta, Peter J Stogios, Alexei Savchenko, Ralph R Isberg, Alexander F Yakunin, Alexander W Ensminger
A random mutagenesis screen enriched for missense mutations in bacterial effector proteins. G3 (Bethesda, Md.) (2024)
Elina Karimullina, Yirui Guo, Hanif M Khan, Tabitha Emde, Bradley Quade, Rosa Di Leo, Zbyszek Otwinowski, D Tieleman Peter, Dominika Borek, Alexei Savchenko
Structural architecture of TolQ-TolR inner membrane protein complex from opportunistic pathogen Acinetobacter baumannii . bioRxiv : the preprint server for biology (2024)
Cameron Semper, Nobuhiko Watanabe, Elina Karimullina, Deepak T Patel, Rosa Di Leo, Mildred Castellanos, Dhruvin H Patel, George Chaconas, Alexei Savchenko
Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain. Nucleic acids research (2024)
Monica Rosas-Lemus, George Minasov, Joseph S Brunzelle, Taha Y Taha, Sofia Lemak, Shaohui Yin, Ludmilla Shuvalova, Julia Rosecrans, Kanika Khanna, H Steven Seifert, Alexei Savchenko, Peter J Stogios, Melanie M Ott, Karla J F Satchell
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains. bioRxiv : the preprint server for biology (2024)
Tiffany V Penner, Neil Lorente Cobo, Deepak T Patel, Dhruvin H Patel, Alexei Savchenko, Ann Karen C Brassinga, Gerd Prehna
Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein science : a publication of the Protein Society 33 (3) (2024)
Lukas Syriste, Deepak T Patel, Peter J Stogios, Tatiana Skarina, Dhruvin Patel, Alexei Savchenko
An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation. mBio 15 (3) (2024)
Chester Pham, Peter J Stogios, Alexei Savchenko, Radhakrishnan Mahadevan
Design and Characterization of a Generalist Biosensor for Indole Derivatives. ACS synthetic biology 13 (7) (2024)
Lukas Syriste, Deepak T Patel, Peter J Stogios, Tatiana Skarina, Dhruvin Patel, Alexei Savchenko
An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation. mBio (2024)
Tiffany V Penner, Neil Lorente Cobo, Deepak T Patel, Dhruvin H Patel, Alexei Savchenko, Ann Karen C Brassinga, Gerd Prehna
Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein science : a publication of the Protein Society 33 (3) (2024)
Cameron Semper, Nobuhiko Watanabe, Elina Karimullina, Deepak T Patel, Rosa Di Leo, Mildred Castellanos, Dhruvin H Patel, George Chaconas, Alexei Savchenko
Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain. Nucleic acids research 52 (14) (2024)
Chester Pham, Mohamed A Nasr, Tatiana Skarina, Rosa Di Leo, David H Kwan, Vincent J J Martin, Peter J Stogios, Radhakrishnan Mahadevan, Alexei Savchenko
Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors. The FEBS journal (2024)
Monica Rosas-Lemus, George Minasov, Joseph S Brunzelle, Taha Y Taha, Sofia Lemak, Shaohui Yin, Ludmilla Shuvalova, Julia Rosecrans, Kanika Khanna, H Steven Seifert, Alexei Savchenko, Peter J Stogios, Melanie M Ott, Karla J F Satchell
Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains. bioRxiv : the preprint server for biology (2024)
Meenakshi Venkatesan, Michael Fruci, Lou Ann Verellen, Tatiana Skarina, Nathalie Mesa, Robert Flick, Chester Pham, Radhakrishnan Mahadevan, Peter J Stogios, Alexei Savchenko
Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics. Nature communications 14 (1) (2023)
Tiffany V Penner, Neil Lorente Cobo, Deepak T Patel, Dhruvin H Patel, Alexei Savchenko, Ann Karen C Brassinga, Gerd Prehna
Structural characterization of the Sel1-like repeat protein LceB from Legionella pneumophila. Protein science : a publication of the Protein Society (2023)
Marco A Distaso, Tatyana N Chernikova, Rafael Bargiela, Cristina Coscolín, Peter J Stogios, José L González-Alfonso, Sofia Lemak, Anna N Khusnutdinova, Francisco J Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A Lunev, Michail M Yakimov, Olga V Golyshina, Manuel Ferrer, Alexander F Yakunin, Peter N Golyshin
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins. Applied and environmental microbiology 89 (2) (2023)
Marco A Distaso, Tatyana N Chernikova, Rafael Bargiela, Cristina Coscolín, Peter J Stogios, José L González-Alfonso, Sofia Lemak, Anna N Khusnutdinova, Francisco J Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A Lunev, Michail M Yakimov, Olga V Golyshina, Manuel Ferrer, Alexander F Yakunin, Peter N Golyshin
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins. Applied and environmental microbiology 89 (2) (2023)
Marco A Distaso, Tatyana N Chernikova, Rafael Bargiela, Cristina Coscolín, Peter J Stogios, José L González-Alfonso, Sofia Lemak, Anna N Khusnutdinova, Francisco J Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A Lunev, Michail M Yakimov, Olga V Golyshina, Manuel Ferrer, Alexander F Yakunin, Peter N Golyshin
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins. Applied and environmental microbiology (2023)
Monica Rosas-Lemus, Supratim Dey, George Minasov, Kemin Tan, Spencer M Anderson, Joseph Brunzelle, Salvatore Nocadello, Ivan Shabalin, Ekaterina Filippova, Andrei Halavaty, Youngchang Kim, Natalia Maltseva, Jerzy Osipiuk, Wladek Minor, Andrzej Joachimiak, Alexei Savchenko, Wayne F Anderson, Karla J F Satchell, null null
A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile . Microbiology resource announcements (2023)
Yirui Guo, Elina Karimullina, Tabitha Emde, Zbyszek Otwinowski, Dominika M Borek, Alexei Savchenko
Monomer and dimer structures of cytochrome bo 3 ubiquinol oxidase from Escherichia coli. Protein science : a publication of the Protein Society (2023)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Correction for Popov et al., "Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice". Infection and immunity (2023)
Marco A Distaso, Tatyana N Chernikova, Rafael Bargiela, Cristina Coscolín, Peter J Stogios, José L González-Alfonso, Sofia Lemak, Anna N Khusnutdinova, Francisco J Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A Lunev, Michail M Yakimov, Olga V Golyshina, Manuel Ferrer, Alexander F Yakunin, Peter N Golyshin
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins. Applied and environmental microbiology 89 (2) (2023)
Emily Bordeleau, Peter J Stogios, Elena Evdokimova, Kalinka Koteva, Alexei Savchenko, Gerard D Wright
Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nature chemical biology (2023)
Jordan D Lin, Peter J Stogios, Kento T Abe, Avril Wang, John MacPherson, Tatiana Skarina, Anne-Claude Gingras, Alexei Savchenko, Alexander W Ensminger
Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila . mBio (2023)
Marco A Distaso, Tatyana N Chernikova, Rafael Bargiela, Cristina Coscolín, Peter J Stogios, José L González-Alfonso, Sofia Lemak, Anna N Khusnutdinova, Francisco J Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A Lunev, Michail M Yakimov, Olga V Golyshina, Manuel Ferrer, Alexander F Yakunin, Peter N Golyshin
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins. Applied and environmental microbiology 89 (2) (2023)
Peter J Stogios, Sean D Liston, Cameron Semper, Bradley Quade, Karolina Michalska, Elena Evdokimova, Shane Ram, Zbyszek Otwinowski, Dominika M Borek, Leah E Cowen, Alexei Savchenko
Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans . Life science alliance 5 (8) (2022)
Peter J Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W D'Souza, Sanket Patel, Gautam Dantas, Gerard D Wright, Alexei Savchenko
Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Communications biology 5 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Melissa R Cruz, Shane Cristy, Shantanu Guha, Giuseppe Buda De Cesare, Elena Evdokimova, Hiram Sanchez, Dominika Borek, Pedro Miramón, Junko Yano, Paul L Fidel, Alexei Savchenko, David R Andes, Peter J Stogios, Michael C Lorenz, Danielle A Garsin
Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections. Nature communications 13 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity (2022)
Antonia C Du Bois, Alice Xue, Chester Pham, Nicole M Revie, Kirsten J Meyer, Yoko Yashiroda, Charles Boone, Justin R Nodwell, Peter Stogios, Alexei Savchenko, Nicole Robbins, Kali R Iyer, Leah E Cowen
High-Throughput Chemical Screen Identifies a 2,5-Disubstituted Pyridine as an Inhibitor of Candida albicans Erg11. mSphere 7 (3) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Georgy Popov, Aline Fiebig-Comyn, Lukas Syriste, Dustin J Little, Tatiana Skarina, Peter J Stogios, Sarah Birstonas, Brian K Coombes, Alexei Savchenko
Distinct Molecular Features of NleG Type 3 Secreted Effectors Allow for Different Roles during Citrobacter rodentium Infection in Mice. Infection and immunity 91 (1) (2022)
Peter W Y Chan, Nilmadhab Chakrabarti, Chris Ing, Ondrej Halgas, Terence K W To, Marielle Wälti, Alain-Pierre Petit, Christopher Tran, Alexei Savchenko, Alexander F Yakunin, Elizabeth A Edwards, Régis Pomès, Emil F Pai
Defluorination Capability of l-2-Haloacid Dehalogenases in the HAD-Like Hydrolase Superfamily Correlates with Active Site Compactness. Chembiochem : a European journal of chemical biology (2021)
Emily Bordeleau, Peter J Stogios, Elena Evdokimova, Kalinka Koteva, Alexei Savchenko, Gerard D Wright
ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin. mBio 12 (1) (2021)
Khorcheska A Batyrova, Anna N Khusnutdinova, Po-Hsiang Wang, Rosa Di Leo, Robert Flick, Elizabeth A Edwards, Alexei Savchenko, Alexander F Yakunin
Biocatalytic in Vitro and in Vivo FMN Prenylation and (De)carboxylase Activation. ACS chemical biology 15 (7) (2020)
Cameron Semper, Peter Stogios, Djalal Meziane-Cherif, Elena Evdokimova, Patrice Courvalin, Alexei Savchenko
Structural characterization of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb from Pseudomonas aeruginosa. Protein science : a publication of the Protein Society 29 (3) (2020)
Peter J Stogios, Alexei Savchenko
Molecular mechanisms of vancomycin resistance. Protein science : a publication of the Protein Society 29 (3) (2020)
Georgy Popov, Elena Evdokimova, Peter J Stogios, Alexei Savchenko
Structure of the full-length Serratia marcescens acetyltransferase AAC(3)-Ia in complex with coenzyme A. Protein science : a publication of the Protein Society 29 (3) (2020)
Tatiana P Fedorchuk, Anna N Khusnutdinova, Elena Evdokimova, Robert Flick, Rosa Di Leo, Peter Stogios, Alexei Savchenko, Alexander F Yakunin
One-Pot Biocatalytic Transformation of Adipic Acid to 6-Aminocaproic Acid and 1,6-Hexamethylenediamine Using Carboxylic Acid Reductases and Transaminases. Journal of the American Chemical Society 142 (2) (2020)
Georgy Popov, Aline Fiebig-Comyn, Steven Shideler, Brian K Coombes, Alexei Savchenko
Complete Genome Sequence of Citrobacter rodentium Strain DBS100. Microbiology resource announcements 8 (24) (2019)
Georgina Cox, Linda Ejim, Peter J Stogios, Kalinka Koteva, Emily Bordeleau, Elena Evdokimova, Arthur O Sieron, Alexei Savchenko, Alisa W Serio, Kevin M Krause, Gerard D Wright
Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS infectious diseases 4 (6) (2018)
Peter J Stogios, Georgina Cox, Haley L Zubyk, Elena Evdokimova, Zdzislaw Wawrzak, Gerard D Wright, Alexei Savchenko
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis. ACS chemical biology 13 (5) (2018)
Andrew T Quaile, Peter J Stogios, Olga Egorova, Elena Evdokimova, Dylan Valleau, Boguslaw Nocek, Purnima S Kompella, Sergio Peisajovich, Alexander F Yakunin, Alexander W Ensminger, Alexei Savchenko
The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. The Journal of biological chemistry 293 (9) (2018)
Zhiyu Xu, Peter J Stogios, Andrew T Quaile, Kevin J Forsberg, Sanket Patel, Tatiana Skarina, Scott Houliston, Cheryl Arrowsmith, Gautam Dantas, Alexei Savchenko
Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes. ACS infectious diseases 3 (9) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Alexei Savchenko