Carsten Krebs

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 55

Top Venues

Journal of the American Chemical Society

Biochemistry

Proceedings of the National Academy of Sciences of the United States of America

Science (New York, N.Y.)

Pennsylvania State University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Pennsylvania State University Jan 01 2002

United States

Faculty

Publications

Evan J Burke, Rachelle A Copeland, Yash Dixit, Carsten Krebs, J Martin Bollinger
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production. Journal of the American Chemical Society 146 (3) (2024)
Juan Pan, Eliott S Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B Grossman, Carsten Krebs, J Martin Bollinger
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO. Biochemistry 63 (13) (2024)
Evan J Burke, Rachelle A Copeland, Yash Dixit, Carsten Krebs, J Martin Bollinger
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production. Journal of the American Chemical Society (2024)
Juan Pan, Eliott S Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B Grossman, Carsten Krebs, J Martin Bollinger
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO. Biochemistry 63 (13) (2024)
Juan Pan, Eliott S Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B Grossman, Carsten Krebs, J Martin Bollinger
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO. Biochemistry 63 (13) (2024)
Juan Pan, Eliott S Wenger, Chi-Yun Lin, Bo Zhang, Debangsu Sil, Irene Schaperdoth, Setareh Saryazdi, Robert B Grossman, Carsten Krebs, J Martin Bollinger
An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO. Biochemistry (2024)
Evan J Burke, Rachelle A Copeland, Yash Dixit, Carsten Krebs, J Martin Bollinger
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production. Journal of the American Chemical Society 146 (3) (2024)
Evan J Burke, Rachelle A Copeland, Yash Dixit, Carsten Krebs, J Martin Bollinger
Steric Perturbation of the Grob-like Final Step of Ethylene-Forming Enzyme Enables 3-Hydroxypropionate and Propylene Production. Journal of the American Chemical Society 146 (3) (2024)
Eliott S Wenger, Ryan J Martinie, Richiro Ushimaru, Christopher J Pollock, Debangsu Sil, Aaron Li, Nhi Hoang, Gavin M Palowitch, Brandt P Graham, Irene Schaperdoth, Evan J Burke, Ailiena O Maggiolo, Wei-Chen Chang, Benjamin D Allen, Carsten Krebs, Alexey Silakov, Amie K Boal, J Martin Bollinger
Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase. Journal of the American Chemical Society (2024)
Jeffrey W Slater, Monica E Neugebauer, Molly J McBride, Debangsu Sil, Chi-Yun Lin, Bryce J Katch, Amie K Boal, Michelle C Y Chang, Alexey Silakov, Carsten Krebs, J Martin Bollinger
Synergistic Binding of the Halide and Cationic Prime Substrate of the l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States. bioRxiv : the preprint server for biology (2023)
Anastasia C Manesis, Jeffrey W Slater, Kenny Cantave, J Martin Bollinger, Carsten Krebs, Amy C Rosenzweig
Capturing a bis -Fe(IV) State in Methylosinus trichosporium OB3b MbnH. Biochemistry (2023)
Anastasia C Manesis, Jeffrey W Slater, Kenny Cantave, J Martin Bollinger, Carsten Krebs, Amy C Rosenzweig
Capturing a bis -Fe(IV) State in Methylosinus trichosporium OB3b MbnH. Biochemistry 62 (5) (2023)
Jeffrey W Slater, Chi-Yun Lin, Monica E Neugebauer, Molly J McBride, Debangsu Sil, Mrutyunjay A Nair, Bryce J Katch, Amie K Boal, Michelle C Y Chang, Alexey Silakov, Carsten Krebs, J Martin Bollinger
Synergistic Binding of the Halide and Cationic Prime Substrate of l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States. Biochemistry (2023)
Anastasia C Manesis, Jeffrey W Slater, Kenny Cantave, J Martin Bollinger, Carsten Krebs, Amy C Rosenzweig
Capturing a bis -Fe(IV) State in Methylosinus trichosporium OB3b MbnH. Biochemistry 62 (5) (2023)
Jeffrey W Slater, Monica E Neugebauer, Molly J McBride, Debangsu Sil, Chi-Yun Lin, Bryce J Katch, Amie K Boal, Michelle C Y Chang, Alexey Silakov, Carsten Krebs, J Martin Bollinger
Synergistic Binding of the Halide and Cationic Prime Substrate of the l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States. bioRxiv : the preprint server for biology (2023)
Anastasia C Manesis, Jeffrey W Slater, Kenny Cantave, J Martin Bollinger, Carsten Krebs, Amy C Rosenzweig
Capturing a bis -Fe(IV) State in Methylosinus trichosporium OB3b MbnH. Biochemistry 62 (5) (2023)
Nunziata Maio, Md Kausar Raza, Yan Li, De-Liang Zhang, J Martin Bollinger, Carsten Krebs, Tracey Ann Rouault
An iron-sulfur cluster in the zinc-binding domain of the SARS-CoV-2 helicase modulates its RNA-binding and -unwinding activities. Proceedings of the National Academy of Sciences of the United States of America 120 (33) (2023)
Molly J McBride, Mrutyunjay A Nair, Debangsu Sil, Jeffrey W Slater, Monica E Neugebauer, Michelle C Y Chang, Amie K Boal, Carsten Krebs, J Martin Bollinger
Substrate-Triggered μ-Peroxodiiron(III) Intermediate in the 4-Chloro-l-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate. Biochemistry 61 (8) (2022)
Syam Sundar Neti, Debangsu Sil, Douglas M Warui, Olga A Esakova, Amy E Solinski, Dante A Serrano, Carsten Krebs, Squire J Booker
Characterization of LipS1 and LipS2 from Thermococcus kodakarensis : Proteins Annotated as Biotin Synthases, which Together Catalyze Formation of the Lipoyl Cofactor. ACS bio & med chem Au 2 (5) (2022)
Douglas M Warui, Debangsu Sil, Kyung-Hoon Lee, Syam Sundar Neti, Olga A Esakova, Hayley L Knox, Carsten Krebs, Squire J Booker
In Vitro Demonstration of Human Lipoyl Synthase Catalytic Activity in the Presence of NFU1. ACS bio & med chem Au 2 (5) (2022)
Hai T Dong, Stephanie Camarena, Debangsu Sil, Michael O Lengel, Jiyong Zhao, Michael Y Hu, E Ercan Alp, Carsten Krebs, Nicolai Lehnert
What Is the Right Level of Activation of a High-Spin {FeNO} 7 Complex to Enable Direct N-N Coupling? Mechanistic Insight into Flavodiiron NO Reductases. Journal of the American Chemical Society 144 (36) (2022)
Nabin Panth, Eliott S Wenger, Carsten Krebs, J Martin Bollinger, Robert B Grossman
Synthesis of 6,6- and 7,7-Difluoro-1-acetamidopyrrolizidines and Their Oxidation Catalyzed by the Nonheme Fe Oxygenase LolO. Chembiochem : a European journal of chemical biology 23 (13) (2022)
Yun Ji Park, Richard J Jodts, Jeffrey W Slater, Reyvin M Reyes, Valerie J Winton, Rana A Montaser, Paul M Thomas, William B Dowdle, Anahi Ruiz, Michael P Snyder, J Martin Bollinger, Carsten Krebs, Brian M Hoffman, Amy C Rosenzweig
A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 119 (13) (2022)
Olga A Esakova, Tyler L Grove, Neela H Yennawar, Arthur J Arcinas, Bo Wang, Carsten Krebs, Steven C Almo, Squire J Booker
Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB. Nature 597 (7877) (2021)
Nunziata Maio, Bernard A P Lafont, Debangsu Sil, Yan Li, J Martin Bollinger, Carsten Krebs, Theodore C Pierson, W Marston Linehan, Tracey Ann Rouault
Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets. Science (New York, N.Y.) 373 (6551) (2021)
Rachelle A Copeland, Shengbin Zhou, Irene Schaperdoth, Tokufu Kent C Shoda, J Martin Bollinger, Carsten Krebs
Hybrid radical-polar pathway for excision of ethylene from 2-oxoglutarate by an iron oxygenase. Science (New York, N.Y.) 373 (6562) (2021)
Rachelle A Copeland, Katherine M Davis, Tokufu Kent C Shoda, Elizabeth J Blaesi, Amie K Boal, Carsten Krebs, J Martin Bollinger
An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme. Journal of the American Chemical Society 143 (5) (2021)
Martin Srnec, Shyam R Iyer, Laura M K Dassama, Kiyoung Park, Shaun D Wong, Kyle D Sutherlin, Yoshitaka Yoda, Yasuhiro Kobayashi, Masayuki Kurokuzu, Makina Saito, Makoto Seto, Carsten Krebs, J Martin Bollinger, Edward I Solomon
Nuclear Resonance Vibrational Spectroscopic Definition of the Facial Triad FeIV═O Intermediate in Taurine Dioxygenase: Evaluation of Structural Contributions to Hydrogen Atom Abstraction. Journal of the American Chemical Society 142 (44) (2020)
Bo Zhang, Arthur J Arcinas, Matthew I Radle, Alexey Silakov, Squire J Booker, Carsten Krebs
First Step in Catalysis of the Radical S-Adenosylmethionine Methylthiotransferase MiaB Yields an Intermediate with a [3Fe-4S]0-Like Auxiliary Cluster. Journal of the American Chemical Society 142 (4) (2020)
Gang Liu, Debangsu Sil, Nunziata Maio, Wing-Hang Tong, J Martin Bollinger, Carsten Krebs, Tracey Ann Rouault
Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase. Nature communications 11 (1) (2020)
Molly J McBride, Debangsu Sil, Tai L Ng, Anne Marie Crooke, Grace E Kenney, Christina R Tysoe, Bo Zhang, Emily P Balskus, Amie K Boal, Carsten Krebs, J Martin Bollinger
A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF. Journal of the American Chemical Society 142 (27) (2020)
Bo Zhang, Lauren J Rajakovich, Devon Van Cura, Elizabeth J Blaesi, Andrew J Mitchell, Christina R Tysoe, Xuejun Zhu, Bennett R Streit, Zhe Rui, Wenjun Zhang, Amie K Boal, Carsten Krebs, J Martin Bollinger
Substrate-Triggered Formation of a Peroxo-Fe2(III/III) Intermediate during Fatty Acid Decarboxylation by UndA. Journal of the American Chemical Society 141 (37) (2019)
Juan Pan, Eliott S Wenger, Megan L Matthews, Christopher J Pollock, Minakshi Bhardwaj, Amelia J Kim, Benjamin D Allen, Robert B Grossman, Carsten Krebs, J Martin Bollinger
Evidence for Modulation of Oxygen Rebound Rate in Control of Outcome by Iron(II)- and 2-Oxoglutarate-Dependent Oxygenases. Journal of the American Chemical Society 141 (38) (2019)
James D Gumkowski, Ryan J Martinie, Patrick S Corrigan, Juan Pan, Matthew R Bauerle, Mohamed Almarei, Squire J Booker, Alexey Silakov, Carsten Krebs, Amie K Boal
Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical S-Adenosylmethionine Enzymes Reveals an Iron-Binding Accessory Domain in a Clostridial Enzyme. Biochemistry 58 (29) (2019)
Lauren J Rajakovich, Maria-Eirini Pandelia, Andrew J Mitchell, Wei-Chen Chang, Bo Zhang, Amie K Boal, Carsten Krebs, J Martin Bollinger
A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases. Biochemistry 58 (12) (2019)
Noah P Dunham, José M Del Río Pantoja, Bo Zhang, Lauren J Rajakovich, Benjamin D Allen, Carsten Krebs, Amie K Boal, J Martin Bollinger
Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1). Journal of the American Chemical Society 141 (25) (2019)
Shengbin Zhou, Juan Pan, Katherine M Davis, Irene Schaperdoth, Bo Wang, Amie K Boal, Carsten Krebs, J Martin Bollinger
Steric Enforcement of cis-Epoxide Formation in the Radical C-O-Coupling Reaction by Which (S)-2-Hydroxypropylphosphonate Epoxidase (HppE) Produces Fosfomycin. Journal of the American Chemical Society 141 (51) (2019)
Ashley B McQuarters, Elizabeth J Blaesi, Jeff W Kampf, E Ercan Alp, Jiyong Zhao, Michael Hu, Carsten Krebs, Nicolai Lehnert
Synthetic Model Complex of the Key Intermediate in Cytochrome P450 Nitric Oxide Reductase. Inorganic chemistry 58 (2) (2019)
Jonathan R Chekan, Chayanid Ongpipattanakul, Terry R Wright, Bo Zhang, J Martin Bollinger, Lauren J Rajakovich, Carsten Krebs, Robert M Cicchillo, Satish K Nair
Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proceedings of the National Academy of Sciences of the United States of America 116 (27) (2019)
Katherine M Davis, Madison Altmyer, Ryan J Martinie, Irene Schaperdoth, Carsten Krebs, J Martin Bollinger, Amie K Boal
Structure of a Ferryl Mimic in the Archetypal Iron(II)- and 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD. Biochemistry 58 (41) (2019)
Hai T Dong, Corey J White, Bo Zhang, Carsten Krebs, Nicolai Lehnert
Non-Heme Diiron Model Complexes Can Mediate Direct NO Reduction: Mechanistic Insight into Flavodiiron NO Reductases. Journal of the American Chemical Society 140 (41) (2018)
Elizabeth J Blaesi, Gavin M Palowitch, Kai Hu, Amelia J Kim, Hannah R Rose, Rahul Alapati, Marshall G Lougee, Hee Jong Kim, Alexander T Taguchi, Kong Ooi Tan, Tatiana N Laremore, Robert G Griffin, Carsten Krebs, Megan L Matthews, Alexey Silakov, J Martin Bollinger, Benjamin D Allen, Amie K Boal
Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical. Proceedings of the National Academy of Sciences of the United States of America 115 (40) (2018)
Hannah R Rose, Manas K Ghosh, Ailiena O Maggiolo, Christopher J Pollock, Elizabeth J Blaesi, Viviane Hajj, Yifeng Wei, Lauren J Rajakovich, Wei-Chen Chang, Yilin Han, Mariana Hajj, Carsten Krebs, Alexey Silakov, Maria-Eirini Pandelia, J Martin Bollinger, Amie K Boal
Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor. Biochemistry 57 (18) (2018)
Bo Wang, Anthony J Blaszczyk, Hayley L Knox, Shengbin Zhou, Elizabeth J Blaesi, Carsten Krebs, Roy X Wang, Squire J Booker
Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase. Biochemistry 57 (33) (2018)
Ryan J Martinie, Elizabeth J Blaesi, J Martin Bollinger, Carsten Krebs, Kenneth D Finkelstein, Christopher J Pollock
Two-Color Valence-to-Core X-ray Emission Spectroscopy Tracks Cofactor Protonation State in a Class I Ribonucleotide Reductase. Angewandte Chemie (International ed. in English) 57 (39) (2018)
Grace E Kenney, Laura M K Dassama, Maria-Eirini Pandelia, Anthony S Gizzi, Ryan J Martinie, Peng Gao, Caroline J DeHart, Luis F Schachner, Owen S Skinner, Soo Y Ro, Xiao Zhu, Monica Sadek, Paul M Thomas, Steven C Almo, J Martin Bollinger, Carsten Krebs, Michael P Snyder, Amy C Rosenzweig
The biosynthesis of methanobactin. Science (New York, N.Y.) 359 (6382) (2018)
Noah P Dunham, Andrew J Mitchell, José M Del Río Pantoja, Carsten Krebs, J Martin Bollinger, Amie K Boal
α-Amine Desaturation of d-Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l-Arginine 3-Hydroxylase, VioC. Biochemistry 57 (46) (2018)
Juan Pan, Minakshi Bhardwaj, Bo Zhang, Wei-Chen Chang, Christopher L Schardl, Carsten Krebs, Robert B Grossman, J Martin Bollinger
Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions. Biochemistry 57 (14) (2018)
Noah P Dunham, Wei-Chen Chang, Andrew J Mitchell, Ryan J Martinie, Bo Zhang, Jonathan A Bergman, Lauren J Rajakovich, Bo Wang, Alexey Silakov, Carsten Krebs, Amie K Boal, J Martin Bollinger
Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance. Journal of the American Chemical Society 140 (23) (2018)
Amy L Speelman, Corey J White, Bo Zhang, E Ercan Alp, Jiyong Zhao, Michael Hu, Carsten Krebs, James Penner-Hahn, Nicolai Lehnert
Non-heme High-Spin {FeNO}6-8 Complexes: One Ligand Platform Can Do It All. Journal of the American Chemical Society 140 (36) (2018)
Kiyoung Park, Ning Li, Yeonju Kwak, Martin Srnec, Caleb B Bell, Lei V Liu, Shaun D Wong, Yoshitaka Yoda, Shinji Kitao, Makoto Seto, Michael Hu, Jiyong Zhao, Carsten Krebs, J Martin Bollinger, Edward I Solomon
Peroxide Activation for Electrophilic Reactivity by the Binuclear Non-heme Iron Enzyme AurF. Journal of the American Chemical Society 139 (20) (2017)
Ryan J Martinie, Elizabeth J Blaesi, Carsten Krebs, J Martin Bollinger, Alexey Silakov, Christopher J Pollock
Evidence for a Di-μ-oxo Diamond Core in the Mn(IV)/Fe(IV) Activation Intermediate of Ribonucleotide Reductase from Chlamydia trachomatis. Journal of the American Chemical Society 139 (5) (2017)
Spencer C Peck, Chen Wang, Laura M K Dassama, Bo Zhang, Yisong Guo, Lauren J Rajakovich, J Martin Bollinger, Carsten Krebs, Wilfred A van der Donk
O-H Activation by an Unexpected Ferryl Intermediate during Catalysis by 2-Hydroxyethylphosphonate Dioxygenase. Journal of the American Chemical Society 139 (5) (2017)
Andrew J Mitchell, Noah P Dunham, Ryan J Martinie, Jonathan A Bergman, Christopher J Pollock, Kai Hu, Benjamin D Allen, Wei-Chen Chang, Alexey Silakov, J Martin Bollinger, Carsten Krebs, Amie K Boal
Visualizing the Reaction Cycle in an Iron(II)- and 2-(Oxo)-glutarate-Dependent Hydroxylase. Journal of the American Chemical Society 139 (39) (2017)
Ryan J Martinie, Christopher J Pollock, Megan L Matthews, J Martin Bollinger, Carsten Krebs, Alexey Silakov
Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes. Inorganic chemistry 56 (21) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Carsten Krebs