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Emily P Balskus (E P Balskus)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 60

Top Venues

Nature communications

Nature

Biochemistry

Nature reviews. Chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Kazuki Nagashima, Aishan Zhao, Katayoon Atabakhsh, Minwoo Bae, Jamie E Blum, Allison Weakley, Sunit Jain, Xiandong Meng, Alice G Cheng, Min Wang, Steven Higginbottom, Alex Dimas, Pallavi Murugkar, Elizabeth S Sattely, James J Moon, Emily P Balskus, Michael A Fischbach
Mapping the T cell repertoire to a complex gut bacterial community. Nature (2023)
Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Complete integration of carbene-transfer chemistry into biosynthesis. Nature 617 (7960) (2023)
Amelia Y M Woo, Miguel A Aguilar Ramos, Rohan Narayan, Khyle C Richards-Corke, Michelle L Wang, Walter J Sandoval-Espinola, Emily P Balskus
Targeting the human gut microbiome with small-molecule inhibitors. Nature reviews. Chemistry 7 (5) (2023)
Duncan J Kountz, Emily P Balskus
A diversified, widespread microbial gene cluster encodes homologs of methyltransferases involved in methanogenesis. bioRxiv : the preprint server for biology (2023)
Amelia Y M Woo, Miguel A Aguilar Ramos, Rohan Narayan, Khyle C Richards-Corke, Michelle L Wang, Walter J Sandoval-Espinola, Emily P Balskus
Targeting the human gut microbiome with small-molecule inhibitors. Nature reviews. Chemistry 7 (5) (2023)
Jared R Mayers, Jack Varon, Ruixuan R Zhou, Martin Daniel-Ivad, Courtney Beaulieu, Amrisha Bholse, Nathaniel R Glasser, Franziska M Lichtenauer, Julie Ng, Mayra Pinilla Vera, Curtis Huttenhower, Mark A Perrella, Andrew T Chan, Sihai D Zhao, Rebecca M Baron, Emily P Balskus
Identification and targeting of microbial putrescine acetylation in bloodstream infections. bioRxiv : the preprint server for biology (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine (2023)
Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Complete integration of carbene-transfer chemistry into biosynthesis. Nature (2023)
Amelia Y M Woo, Miguel A Aguilar Ramos, Rohan Narayan, Khyle C Richards-Corke, Michelle L Wang, Walter J Sandoval-Espinola, Emily P Balskus
Targeting the human gut microbiome with small-molecule inhibitors. Nature reviews. Chemistry 7 (5) (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine 29 (3) (2023)
Amelia Y M Woo, Miguel A Aguilar Ramos, Rohan Narayan, Khyle C Richards-Corke, Michelle L Wang, Walter J Sandoval-Espinola, Emily P Balskus
Publisher Correction: Targeting the human gut microbiome with small-molecule inhibitors. Nature reviews. Chemistry (2023)
Dominick J Jenkins, Benjamin M Woolston, M Indriati Hood-Pishchany, Paula Pelayo, Alyssa N Konopaski, M Quinn Peters, Michael T France, Jacques Ravel, Caroline M Mitchell, Seth Rakoff-Nahoum, Christopher Whidbey, Emily P Balskus
Bacterial amylases enable glycogen degradation by the vaginal microbiome. Nature microbiology (2023)
Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Complete integration of carbene-transfer chemistry into biosynthesis. Nature 617 (7960) (2023)
Amelia Y M Woo, Miguel A Aguilar Ramos, Rohan Narayan, Khyle C Richards-Corke, Michelle L Wang, Walter J Sandoval-Espinola, Emily P Balskus
Targeting the human gut microbiome with small-molecule inhibitors. Nature reviews. Chemistry (2023)
Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Complete integration of carbene-transfer chemistry into biosynthesis. Nature 617 (7960) (2023)
Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Andrew T Chan, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nature medicine 29 (3) (2023)
Noa Mandelbaum, Lihan Zhang, Shaqed Carasso, Tamar Ziv, Sapir Lifshiz-Simon, Irina Davidovich, Ishai Luz, Elliot Berinstein, Tal Gefen, Tomer Cooks, Yeshayahu Talmon, Emily P Balskus, Naama Geva-Zatorsky
Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects. NPJ biofilms and microbiomes 9 (1) (2023)
Teresa P Martins, Nathaniel R Glasser, Duncan J Kountz, Paulo Oliveira, Emily P Balskus, Pedro N Leão
Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A. ACS chemical biology (2022)
Seth M Bloom, Nomfuneko A Mafunda, Benjamin M Woolston, Matthew R Hayward, Josephine F Frempong, Aaron B Abai, Jiawu Xu, Alissa J Mitchell, Xavier Westergaard, Fatima Aysha Hussain, Nondumiso Xulu, Mary Dong, Krista L Dong, Thandeka Gumbi, F Xolisile Ceasar, Justin K Rice, Namit Choksi, Nasreen Ismail, Thumbi Ndung'u, Musie S Ghebremichael, David A Relman, Emily P Balskus, Caroline M Mitchell, Douglas S Kwon
Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation. Nature microbiology 7 (3) (2022)
Matthew R Volpe, José A Velilla, Martin Daniel-Ivad, Jenny J Yao, Alessia Stornetta, Peter W Villalta, Hsin-Che Huang, Daniel A Bachovchin, Silvia Balbo, Rachelle Gaudet, Emily P Balskus
A small molecule inhibitor prevents gut bacterial genotoxin production. Nature chemical biology (2022)
José A Velilla, Matthew R Volpe, Grace E Kenney, Richard M Walsh, Emily P Balskus, Rachelle Gaudet
Structural basis of colibactin activation by the ClbP peptidase. Nature chemical biology (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Justin E Silpe, Joel W H Wong, Siân V Owen, Michael H Baym, Emily P Balskus
The bacterial toxin colibactin triggers prophage induction. Nature 603 (7900) (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Emily P Balskus
Elucidating the Chemistry and Biology of the Human Microbiome. Biochemistry 61 (24) (2022)
Emily P Balskus
Elucidating the Chemistry and Biology of the Human Microbiome. Biochemistry 61 (24) (2022)
Nathaniel R Braffman, Terry B Ruskoski, Katherine M Davis, Nathaniel R Glasser, Cassidy Johnson, C Denise Okafor, Amie K Boal, Emily P Balskus
Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis. eLife 11 (2022)
Beverly Fu, Azadeh Nazemi, Benjamin J Levin, Zhongyue J Yang, Heather J Kulik, Emily P Balskus
Mechanistic Studies of a Skatole-Forming Glycyl Radical Enzyme Suggest Reaction Initiation via Hydrogen Atom Transfer. Journal of the American Chemical Society 144 (25) (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Xueyang Dong, Ben G H Guthrie, Margaret Alexander, Cecilia Noecker, Lorenzo Ramirez, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators. Nature communications 13 (1) (2022)
Kevin J Murray, Erik S Carlson, Alessia Stornetta, Emily P Balskus, Peter W Villalta, Silvia Balbo
Extension of Diagnostic Fragmentation Filtering for Automated Discovery in DNA Adductomics. Analytical chemistry 93 (14) (2021)
Lauren J Rajakovich, Beverly Fu, Maud Bollenbach, Emily P Balskus
Elucidation of an anaerobic pathway for metabolism of l-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria. Proceedings of the National Academy of Sciences of the United States of America 118 (32) (2021)
Duncan J Kountz, Emily P Balskus
Leveraging Microbial Genomes and Genomic Context for Chemical Discovery. Accounts of chemical research 54 (13) (2021)
Vayu M Rekdal, Paola Nol Bernadino, Michael U Luescher, Sina Kiamehr, Chip Le, Jordan E Bisanz, Peter J Turnbaugh, Elizabeth N Bess, Emily P Balskus
A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. eLife 9 (2020)
Lindsey Rf Backman, Yolanda Y Huang, Mary C Andorfer, Brian Gold, Ronald T Raines, Emily P Balskus, Catherine L Drennan
Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme. eLife 9 (2020)
Molly J McBride, Debangsu Sil, Tai L Ng, Anne Marie Crooke, Grace E Kenney, Christina R Tysoe, Bo Zhang, Emily P Balskus, Amie K Boal, Carsten Krebs, J Martin Bollinger
A Peroxodiiron(III/III) Intermediate Mediating Both N-Hydroxylation Steps in Biosynthesis of the N-Nitrosourea Pharmacophore of Streptozotocin by the Multi-domain Metalloenzyme SznF. Journal of the American Chemical Society 142 (27) (2020)
Emily P Balskus
The Human Microbiome. ACS infectious diseases 4 (1) (2019)
Tai L Ng, Monica E McCallum, Christine R Zheng, Jennifer X Wang, Kelvin J Y Wu, Emily P Balskus
The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis. Chembiochem : a European journal of chemical biology 21 (8) (2019)
Erica E Schultz, Nathaniel R Braffman, Michael U Luescher, Harry H Hager, Emily P Balskus
Biocatalytic Friedel-Crafts Alkylation Using a Promiscuous Biosynthetic Enzyme. Angewandte Chemie (International ed. in English) 58 (10) (2019)
Matthew R Wilson, Yindi Jiang, Peter W Villalta, Alessia Stornetta, Paul D Boudreau, Andrea Carrá, Caitlin A Brennan, Eunyoung Chun, Lizzie Ngo, Leona D Samson, Bevin P Engelward, Wendy S Garrett, Silvia Balbo, Emily P Balskus
The human gut bacterial genotoxin colibactin alkylates DNA. Science (New York, N.Y.) 363 (6428) (2019)
Vayu M Rekdal, Elizabeth N Bess, Jordan E Bisanz, Peter J Turnbaugh, Emily P Balskus
Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism. Science (New York, N.Y.) 364 (6445) (2019)
Matthew R Volpe, Matthew R Wilson, Carolyn A Brotherton, Ethan S Winter, Sheila E Johnson, Emily P Balskus
In Vitro Characterization of the Colibactin-Activating Peptidase ClbP Enables Development of a Fluorogenic Activity Probe. ACS chemical biology 14 (6) (2019)
Yindi Jiang, Alessia Stornetta, Peter W Villalta, Matthew R Wilson, Paul D Boudreau, Li Zha, Silvia Balbo, Emily P Balskus
Reactivity of an Unusual Amidase May Explain Colibactin's DNA Cross-Linking Activity. Journal of the American Chemical Society 141 (29) (2019)
Matthew R Volpe, Matthew R Wilson, Carolyn A Brotherton, Ethan S Winter, Sheila E Johnson, Emily P Balskus
In Vitro Characterization of the Colibactin-Activating Peptidase ClbP Enables Design of a Fluorogenic Activity Probe. ACS chemical biology 14 (9) (2019)
Abraham J Waldman, Emily P Balskus
Discovery of a Diazo-Forming Enzyme in Cremeomycin Biosynthesis. The Journal of organic chemistry 83 (14) (2018)
Vayu M Rekdal, Emily P Balskus
Gut Microbiota: Rational Manipulation of Gut Bacterial Metalloenzymes Provides Insights into Dysbiosis and Inflammation. Biochemistry 57 (16) (2018)
Carina L Chittim, Stephania M Irwin, Emily P Balskus
Deciphering Human Gut Microbiota-Nutrient Interactions: A Role for Biochemistry. Biochemistry 57 (18) (2018)
Nitzan Koppel, Jordan E Bisanz, Maria-Eirini Pandelia, Peter J Turnbaugh, Emily P Balskus
Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins. eLife 7 (2018)
Nitzan Koppel, Vayu M Rekdal, Emily P Balskus
Chemical transformation of xenobiotics by the human gut microbiota. Science (New York, N.Y.) 356 (6344) (2018)
Carina L Chittim, Ana Martínez Del Campo, Emily P Balskus
Gut bacterial phospholipase Ds support disease-associated metabolism by generating choline. Nature microbiology 4 (1) (2018)
Kwo-Kwang A Wang, Tai L Ng, Peng Wang, Zedu Huang, Emily P Balskus, Wilfred A van der Donk
Glutamic acid is a carrier for hydrazine during the biosyntheses of fosfazinomycin and kinamycin. Nature communications 9 (1) (2018)
Benjamin J Levin, Emily P Balskus
Characterization of 1,2-Propanediol Dehydratases Reveals Distinct Mechanisms for B12-Dependent and Glycyl Radical Enzymes. Biochemistry 57 (23) (2018)
Marina Orman, Smaranda Bodea, Michael A Funk, Ana Martínez-Del Campo, Maud Bollenbach, Catherine L Drennan, Emily P Balskus
Structure-Guided Identification of a Small Molecule That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. Journal of the American Chemical Society 141 (1) (2018)
Emily P Balskus, Peter J Turnbaugh, Dennis W Wolan
Announcement of 2019 Keystone Symposia Conference: "Microbiome: Chemical Mechanisms and Biological Consequences". mSystems 3 (4) (2018)
Abraham J Waldman, Emily P Balskus
The Human Microbiota, Infectious Disease, and Global Health: Challenges and Opportunities. ACS infectious diseases 4 (1) (2017)
Peng Wang, Gloria J Hong, Matthew R Wilson, Emily P Balskus
Production of Stealthin C Involves an S-N-Type Smiles Rearrangement. Journal of the American Chemical Society 139 (8) (2017)
Abraham J Waldman, Tai L Ng, Peng Wang, Emily P Balskus
Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis. Chemical reviews 117 (8) (2017)
Benjamin J Levin, Yolanda Y Huang, Spencer C Peck, Y Wei, A Martínez-Del Campo, J A Marks, E A Franzosa, Curtis Huttenhower, Emily P Balskus
A prominent glycyl radical enzyme in human gut microbiomes metabolizes trans-4-hydroxy-l-proline. Science (New York, N.Y.) 355 (6325) (2017)

Emily P Balskus.css-eqlu8i{font-size:small;padding-left:4px;} (E P Balskus)

Publication Activity (10 Years)

Top Topics

Top Venues

Emily P Balskus (E P Balskus)