Changning Wang

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 30

Top Topics

Positron Emission Tomography

Top Venues

Journal of medicinal chemistry

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Chemical communications (Cambridge, England)

Molecular pharmaceutics

This page only lists publications with an associated author ORCID identifier.

Publications

Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N Gomperts, Hsiao-Ying Wey, Shiqian Shen, Rudolph E Tanzi, Changning Wang, Can Zhang
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (32) (2024)
Ping Bai, Frederick A Bagdasarian, Yulong Xu, Yanli Wang, Yongle Wang, Ashley Gomm, Yanting Zhou, Rui Wu, Hsiao-Ying Wey, Rudolph E Tanzi, Can Martin Zhang, Yu Lan, Changning Wang
Molecular Imaging of Alzheimer's Disease-Related Sigma-1 Receptor in the Brain via a Novel Ru-Mediated Aromatic 18 F-deoxyfluorination Probe. Journal of medicinal chemistry 67 (8) (2024)
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N Gomperts, Hsiao-Ying Wey, Shiqian Shen, Rudolph E Tanzi, Changning Wang, Can Zhang
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (32) (2024)
Yanli Wang, Yongle Wang, Yulong Xu, Darcy Tocci, Changning Wang
Development and Evaluation of [ 11 C]I-58: A Novel PET Radiotracer Targeting BRD4 BD2 for Advanced Epigenetic Imaging. ACS omega 9 (34) (2024)
Ping Bai, Frederick A Bagdasarian, Yulong Xu, Yanli Wang, Yongle Wang, Ashley Gomm, Yanting Zhou, Rui Wu, Hsiao-Ying Wey, Rudolph E Tanzi, Can Martin Zhang, Yu Lan, Changning Wang
Molecular Imaging of Alzheimer's Disease-Related Sigma-1 Receptor in the Brain via a Novel Ru-Mediated Aromatic 18 F-deoxyfluorination Probe. Journal of medicinal chemistry (2024)
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N Gomperts, Hsiao-Ying Wey, Shiqian Shen, Rudolph E Tanzi, Changning Wang, Can Zhang
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (32) (2024)
Yanli Wang, Yongle Wang, Yulong Xu, Darcy Tocci, Changning Wang
Development and Evaluation of [ 11 C]I-58: A Novel PET Radiotracer Targeting BRD4 BD2 for Advanced Epigenetic Imaging. ACS omega 9 (34) (2024)
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A Bagdasarian, Madelyn Hallisey, Breanna Varela, Se Hoon Choi, Stephen N Gomperts, Hsiao-Ying Wey, Shiqian Shen, Rudolph E Tanzi, Changning Wang, Can Zhang
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Savannah Biby, Prasenjit Mondal, Yiming Xu, Ashley Gomm, Baljit Kaur, Jannatun N Namme, Changning Wang, Rudolph E Tanzi, Shijun Zhang, Can Martin Zhang
Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome. ACS chemical neuroscience (2024)
Ping Bai, Yu Lan, Yan Liu, Prasenjit Mondal, Ashley Gomm, Yulong Xu, Yanli Wang, Yongle Wang, Leyi Kang, Lili Pan, Frederick A Bagdasarian, Madelyn Hallisey, Fleur Lobo, Breanna Varela, Se Hoon Choi, Stephen N Gomperts, Hsiao-Ying Wey, Shiqian Shen, Rudolph E Tanzi, Changning Wang, Can Zhang
Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 11 (32) (2024)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry 67 (1) (2023)
Ping Bai, Yan Liu, Liuyue Yang, Weihua Ding, Prasenjit Mondal, Na Sang, Gang Liu, Xiaoxia Lu, Thanh Tu Ho, Yanting Zhou, Rui Wu, Vishal C Birar, Moses Q Wilks, Rudolph E Tanzi, Hening Lin, Can Martin Zhang, Wei-Min Li, Shiqian Shen, Changning Wang
Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice. Journal of medicinal chemistry (2023)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry 67 (1) (2023)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry 67 (1) (2023)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry 67 (1) (2023)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry (2023)
Yiming Xu, Yulong Xu, Savannah Biby, Baljit Kaur, Yan Liu, Frederick Andrew Bagdasarian, Hsiao-Ying Wey, Rudolph Tanzi, Can Martin Zhang, Changning Wang, Shijun Zhang
Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. Journal of medicinal chemistry 67 (1) (2023)
Yan Liu, Zude Chen, Yanli Wang, Madelyn Rose Hallisey, Breanna Lizeth Varela, Anne Siewko, Darcy Tocci, Changning Wang, Yulong Xu
Noninvasive Positron Emission Tomography Imaging of SIRT1 in a Model of Early-Stage Alcoholic Liver Disease. Molecular pharmaceutics (2023)
Prasenjit Mondal, Ping Bai, Ashley Gomm, Grisilda Bakiasi, Chih-Chung Jerry Lin, Yanli Wang, Se Hoon Choi, Rudolph E Tanzi, Changning Wang, Can Martin Zhang
Structure-Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2023)
Paris R Watson, Ping Bai, Changning Wang, Abigail D Cragin, Jacob M Hooker, David W Christianson
Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6. Biochemistry 61 (18) (2022)
Gengyang Yuan, Maeva Dhaynaut, Yu Lan, Nicolas J Guehl, Dalena Huynh, Suhasini M Iyengar, Sepideh Afshar, Manish Kumar Jain, Julie E Pickett, Hye Jin Kang, Hao Wang, Sung-Hyun Moon, Mary Jo Ondrechen, Changning Wang, Timothy M Shoup, Georges El Fakhri, Marc D Normandin, Anna-Liisa Brownell
Synthesis and Characterization of 5-(2-Fluoro-4-[ 11 C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2 H -pyrano[2,3- b ]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. Journal of medicinal chemistry 65 (3) (2022)
Zude Chen, Riwei Yang, Yulong Xu, Leqi Liang, Shan Ao, Zuomin Wang, Ping Bai, Di Gu, Xiaolu Duan, Yongda Liu, Wen Zhong, Peng Xu, Tuo Deng, Guohua Zeng, Changning Wang
PET Imaging of Bromodomain and Extra-Terminal Domain Inhibitors for the Noninvasive Assessment of Metabolic Changes in the Liver and Brain of Early-Stage Alcoholic Liver Disease. Molecular pharmaceutics 19 (7) (2022)
Ping Bai, Liu Yan, Frederick A Bagdasarian, Moses Q Wilks, Hsiao-Ying Wey, Changning Wang
A positron emission tomography imaging probe selectively targeting the BD1 bromodomain and extra-terminal domain. Chemical communications (Cambridge, England) 58 (69) (2022)
Biyue Zhu, Jing Yang, Richard Van, Fan Yang, Yue Yu, Astra Yu, Kathleen Ran, Keyi Yin, Yingxia Liang, Xunuo Shen, Wei Yin, Se Hoon Choi, Ying Lu, Changning Wang, Yihan Shao, Liang Shi, Rudolph E Tanzi, Can Zhang, Yan Cheng, Zhirong Zhang, ChongZhao Ran
Epitope alteration by small molecules and applications in drug discovery. Chemical science 13 (27) (2022)
Yu Lan, Ping Bai, Yan Liu, Sepideh Afshar, Robin Striar, Anna Kathryn Rattray, Tyler Nicholas Meyer, Amelia G Langan, Alisa M Posner, Shiqian Shen, Rudolph E Tanzi, Can Martin Zhang, Changning Wang
Visualization of Receptor-Interacting Protein Kinase 1 (RIPK1) by Brain Imaging with Positron Emission Tomography. Journal of medicinal chemistry 64 (20) (2021)
Sha Chen, Songtao Yu, Zaizhi Du, Xie Huang, Meng He, Shuang Long, Jing Liu, Yu Lan, Dong Yang, Hao Wang, Shuhui Li, An Chen, Yuhui Hao, Yongping Su, Changning Wang, Shenglin Luo
Synthesis of Mitochondria-Anchored Nitroimidazoles with a Versatile NIR Fluorophore for Hypoxic Tumor-Targeting Imaging and Chemoradiotherapy. Journal of medicinal chemistry 64 (6) (2021)
Ping Bai, Yu Lan, Debasis Patnaik, Hao Wang, Yan Liu, Zude Chen, Gengyang Yuan, Sepideh Afshar, Robin Striar, Julia S Zagaroli, Darcy R Tocci, Amelia G Langan, Stephen J Haggarty, Changning Wang
Design, Synthesis, and Evaluation of Thienodiazepine Derivatives as Positron Emission Tomography Imaging Probes for Bromodomain and Extra-Terminal Domain Family Proteins. Journal of medicinal chemistry 64 (19) (2021)
Yulong Xu, Yiming Xu, Savannah Biby, Ping Bai, Yan Liu, Can Martin Zhang, Changning Wang, Shijun Zhang
Novel Positron Emission Tomography Radiotracers for Imaging Mitochondrial Complex I. ACS chemical neuroscience (2021)
Ping Bai, Yu Lan, Hao Wang, Yan Liu, Robin Striar, Gengyang Yuan, Sepideh Afshar, Julia S Zagaroli, Darcy R Tocci, Amelia G Langan, Changning Wang
Synthesis and Characterization of a Positron Emission Tomography Imaging Probe Selectively Targeting the Second Bromodomain of Bromodomain Protein BRD4. Bioconjugate chemistry 32 (8) (2021)
Ping Bai, Hsiao-Ying Wey, Debasis Patnaik, Xiaoxia Lu, Yu Lan, Johanna Rokka, Fiedler Stephanie, Stephen J Haggarty, Changning Wang
Positron emission tomography probes targeting bromodomain and extra-terminal (BET) domains to enable in vivo neuroepigenetic imaging. Chemical communications (Cambridge, England) 55 (86) (2019)