Manish Kumar Jain (Jain Manish Kumar, Manish K Jain)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 22

Top Topics

Low Density Lipoprotein

Major Depressive Disorder

Top Venues

Science (New York, N.Y.)

Journal of medicinal chemistry

ACS chemical neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Author Correction: Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) 384 (6702) (2024)
Jiankun Lyu, Nicholas J Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish Kumar Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey F DiBerto, Kuglae Kim, Isabella S Glenn, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii S Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
AlphaFold2 structures guide prospective ligand discovery. Science (New York, N.Y.) (2024)
Yoojoong Kim, Ryan H Gumpper, Yong-Feng Liu, D Dewran Kocak, Yan Xiong, Can Cao, Zhijie Deng, Brian E Krumm, Manish Kumar Jain, Shicheng Zhang, Jian Jin, Bryan L Roth
Bitter taste receptor activation by cholesterol and an intracellular tastant. Nature 628 (8008) (2024)
Gengyang Yuan, Maeva Dhaynaut, Nicolas J Guehl, Sepideh Afshar, Dalena Huynh, Sung-Hyun Moon, Suhasini M Iyengar, Manish Kumar Jain, Julie E Pickett, Hye Jin Kang, Mary Jo Ondrechen, Georges El Fakhri, Marc D Normandin, Anna-Liisa Brownell
Design, Synthesis, and Characterization of [ 18 F]mG2P026 as a High-Contrast PET Imaging Ligand for Metabotropic Glutamate Receptor 2. Journal of medicinal chemistry 65 (14) (2022)
Gengyang Yuan, Maeva Dhaynaut, Yu Lan, Nicolas J Guehl, Dalena Huynh, Suhasini M Iyengar, Sepideh Afshar, Manish Kumar Jain, Julie E Pickett, Hye Jin Kang, Hao Wang, Sung-Hyun Moon, Mary Jo Ondrechen, Changning Wang, Timothy M Shoup, Georges El Fakhri, Marc D Normandin, Anna-Liisa Brownell
Synthesis and Characterization of 5-(2-Fluoro-4-[ 11 C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2 H -pyrano[2,3- b ]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. Journal of medicinal chemistry 65 (3) (2022)
Gavin P Schmitz, Manish Kumar Jain, Samuel T Slocum, Bryan L Roth
5-HT 2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics. ACS chemical neuroscience 13 (16) (2022)
Anat Levit Kaplan, Danielle N Confair, Kuglae Kim, Ximena Barros-Álvarez, Ramona M Rodriguiz, Ying Yang, Oh Sang Kweon, Tao Che, John D McCorvy, David N Kamber, James P Phelan, Luan Carvalho Martins, Vladimir M Pogorelov, Jeffrey F DiBerto, Samuel T Slocum, Xi-Ping Huang, Manish Kumar Jain, Michael J Robertson, Ouliana Panova, Alpay B Seven, Autumn Q Wetsel, William C Wetsel, John J Irwin, Georgios Skiniotis, Brian K Shoichet, Bryan L Roth, Jonathan A Ellman
Bespoke library docking for 5-HT 2A receptor agonists with antidepressant activity. Nature 610 (7932) (2022)
Arman A Sadybekov, Anastasiia V Sadybekov, Yong-Feng Liu, Christos Iliopoulos-Tsoutsouvas, Xi-Ping Huang, Julie E Pickett, Blake Houser, Nilkanth Patel, Ngan K Tran, Fei Tong, Nikolai Zvonok, Manish Kumar Jain, Olena Savych, Dmytro S Radchenko, Spyros P Nikas, Nicos A Petasis, Yurii S Moroz, Bryan L Roth, Alexandros Makriyannis, Vsevolod Katritch
Synthon-based ligand discovery in virtual libraries of over 11 billion compounds. Nature 601 (7893) (2021)