Hening Lin (H Lin)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 106

Top Venues

ACS chemical biology

Proceedings of the National Academy of Sciences of the United States of America

Biochemistry

Journal of the American Chemical Society

This page only lists publications with an associated author ORCID identifier.

Publications

Bingsen Zhang, Yan Yu, Bennett W Fox, Yinong Liu, Venkatesh P Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C Schroeder
Amino acid and protein specificity of protein fatty acylation in C. elegans . Proceedings of the National Academy of Sciences of the United States of America 121 (5) (2024)
Sadhan Jana, Jialin Shang, Jun Young Hong, Michael K Fenwick, Rishi Puri, Xuan Lu, Ari M Melnick, Meng Li, Hening Lin
A Mitochondria-Targeting SIRT3 Inhibitor with Activity against Diffuse Large B Cell Lymphoma. Journal of medicinal chemistry (2024)
Yinong Liu, Dan Hou, Wenzhe Chen, Xuan Lu, Garrison P Komaniecki, Yilai Xu, Tao Yu, Sophia M Zhang, Maurine E Linder, Hening Lin
MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology 19 (2) (2024)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
Correction to "A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain". ACS chemical biology 19 (4) (2024)
Yinong Liu, Dan Hou, Wenzhe Chen, Xuan Lu, Garrison P Komaniecki, Yilai Xu, Tao Yu, Sophia M Zhang, Maurine E Linder, Hening Lin
MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Edward William Tate, Lior Soday, Ana Losada de la Lastra, Mei Wang, Hening Lin
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets. Nature reviews. Cancer (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology 19 (2) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology 19 (2) (2024)
Bingsen Zhang, Yan Yu, Bennett W Fox, Yinong Liu, Venkatesh P Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C Schroeder
Amino acid and protein specificity of protein fatty acylation in C. elegans . Proceedings of the National Academy of Sciences of the United States of America 121 (5) (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology 19 (5) (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
Correction to "A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain". ACS chemical biology 19 (4) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology 19 (2) (2024)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
Correction to "A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain". ACS chemical biology (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology 19 (5) (2024)
Bingsen Zhang, Yan Yu, Bennett W Fox, Yinong Liu, Venkatesh P Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C Schroeder
Amino acid and protein specificity of protein fatty acylation in C. elegans . Proceedings of the National Academy of Sciences of the United States of America 121 (5) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology (2024)
Yinong Liu, Dan Hou, Wenzhe Chen, Xuan Lu, Garrison P Komaniecki, Yilai Xu, Tao Yu, Sophia M Zhang, Maurine E Linder, Hening Lin
MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Bingsen Zhang, Yan Yu, Bennett W Fox, Yinong Liu, Venkatesh P Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C Schroeder
Amino acid and protein specificity of protein fatty acylation in C. elegans . Proceedings of the National Academy of Sciences of the United States of America 121 (5) (2024)
Kewen Peng, Ananya Anmangandla, Sadhan Jana, Yizhen Jin, Hening Lin
Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS chemical biology 19 (2) (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology 19 (5) (2024)
Edward William Tate, Lior Soday, Ana Losada de la Lastra, Mei Wang, Hening Lin
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets. Nature reviews. Cancer 24 (4) (2024)
Dan Hou, Tao Yu, Xuan Lu, Jun Young Hong, Min Yang, Yanlin Zi, Thanh Tu Ho, Hening Lin
Sirt2 inhibition improves gut epithelial barrier integrity and protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America 121 (18) (2024)
Yinong Liu, Dan Hou, Wenzhe Chen, Xuan Lu, Garrison P Komaniecki, Yilai Xu, Tao Yu, Sophia M Zhang, Maurine E Linder, Hening Lin
MAVS Cys508 palmitoylation promotes its aggregation on the mitochondrial outer membrane and antiviral innate immunity. Proceedings of the National Academy of Sciences of the United States of America 121 (34) (2024)
Edward William Tate, Lior Soday, Ana Losada de la Lastra, Mei Wang, Hening Lin
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets. Nature reviews. Cancer 24 (4) (2024)
Bingsen Zhang, Yan Yu, Bennett W Fox, Yinong Liu, Venkatesh P Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C Schroeder
Amino acid and protein specificity of protein fatty acylation in C. elegans . Proceedings of the National Academy of Sciences of the United States of America 121 (5) (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology 19 (5) (2024)
Edward William Tate, Lior Soday, Ana Losada de la Lastra, Mei Wang, Hening Lin
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets. Nature reviews. Cancer 24 (4) (2024)
Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Jialin Shang, Ananya Anmangandla, Sadhan Jana, J Christopher Fromme, Hening Lin
GS-441524-Diphosphate-Ribose Derivatives as Nanomolar Binders and Fluorescence Polarization Tracers for SARS-CoV-2 and Other Viral Macrodomains. ACS chemical biology 19 (5) (2024)
Thanh Tu Ho, Changmin Peng, Edward Seto, Hening Lin
Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11. ACS chemical biology (2023)
Hening Lin
Christopher T. Walsh: A Prolific Scientist, Effective Academic Leader, and Responsive Mentor. ACS chemical biology (2023)
Ping Bai, Yan Liu, Liuyue Yang, Weihua Ding, Prasenjit Mondal, Na Sang, Gang Liu, Xiaoxia Lu, Thanh Tu Ho, Yanting Zhou, Rui Wu, Vishal C Birar, Moses Q Wilks, Rudolph E Tanzi, Hening Lin, Can Martin Zhang, Wei-Min Li, Shiqian Shen, Changning Wang
Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice. Journal of medicinal chemistry (2023)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology (2023)
Zhipeng A Wang, Jonathan W Markert, Samuel D Whedon, Maheeshi Yapa Abeywardana, Kwangwoon Lee, Hanjie Jiang, Carolay Suarez, Hening Lin, Lucas Farnung, Philip A Cole
Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation. Journal of the American Chemical Society (2023)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology 18 (5) (2023)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology (2023)
Yi Jiang, Yuejie Xu, Cheng-Liang Zhu, Guifang Xu, Lei Xu, Zijian Rao, Lixing Zhou, Ping Jiang, Sara Malik, Jing-Yuan Fang, Hening Lin, Mingming Zhang
STAT3 palmitoylation initiates a positive feedback loop that promotes the malignancy of hepatocellular carcinoma cells in mice. Science signaling 16 (814) (2023)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology 18 (5) (2023)
Michael R Smith, Le Zhang, Yizhen Jin, Min Yang, Anusha Bade, Kevin D Gillis, Sadhan Jana, Ramesh Naidu Bypaneni, Timothy E Glass, Hening Lin
A Turn-On Fluorescent Amino Acid Sensor Reveals Chloroquine's Effect on Cellular Amino Acids via Inhibiting Cathepsin L. ACS central science 9 (5) (2023)
Ananya Anmangandla, Sadhan Jana, Kewen Peng, Shamar D Wallace, Saket Rahul Bagde, Bryon S Drown, Jiashu Xu, Paul J Hergenrother, J Christopher Fromme, Hening Lin
A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS chemical biology 18 (5) (2023)
Rushita A Bagchi, Emma L Robinson, Tianjing Hu, Ji Cao, Jun Young Hong, Charles A Tharp, Hanan Qasim, Kathleen M Gavin, Julie Pires Da Silva, Jennifer L Major, Bradley K McConnell, Edward Seto, Hening Lin, Timothy A McKinsey
Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling. Proceedings of the National Academy of Sciences of the United States of America 119 (7) (2022)
Shuai Zhang, Ornella D Nelson, Ian R Price, Cheng-Liang Zhu, Xuan Lu, Irma R Fernandez, Robert Samuel Weiss, Hening Lin
Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis. Proceedings of the National Academy of Sciences of the United States of America 119 (11) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
A Vogelmann, Matthias Schiedel, N Wössner, A Merz, D Herp, S Hammelmann, A Colcerasa, G Komaniecki, J Y Hong, M Sum, E Metzger, E Neuwirt, L Zhang, O Einsle, O Groß, R Schüle, Hening Lin, Wolfgang Sippl, Manfred Jung
Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration. RSC chemical biology 3 (4) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
Yun Yang, Victor Tapias, Diana Acosta, Hui Xu, Huanlian Chen, Ruchika Bhawal, Elizabeth T Anderson, Elena Ivanova, Hening Lin, Botir T Sagdullaev, Jianer Chen, William L Klein, Kirsten L Viola, Samuel E Gandy, Vahram Haroutunian, M Flint Beal, David Eliezer, Sheng Zhang, Gary E Gibson
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease. Nature communications 13 (1) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
Garrison P Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J Windle, Mikhail G Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Astrocyte Elevated Gene-1 Cys75 S -Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry 62 (2) (2022)
Arash Latifkar, Fangyu Wang, James J Mullmann, Elena Panizza, Irma R Fernandez, Lu Ling, Andrew D Miller, Claudia Fischbach, Robert Samuel Weiss, Hening Lin, Richard A Cerione, Marc A Antonyak
IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proceedings of the National Academy of Sciences of the United States of America 119 (45) (2022)
Zhipeng A Wang, Samuel D Whedon, Mingxuan Wu, Siyu Wang, Edward A Brown, Ananya Anmangandla, Liam Regan, Kwangwoon Lee, Jianfeng Du, Jun Young Hong, Louise Fairall, Taylor Kay, Hening Lin, Yingming Zhao, John W R Schwabe, Philip A Cole
Histone H2B Deacylation Selectivity: Exploring Chromatin's Dark Matter with an Engineered Sortase. Journal of the American Chemical Society 144 (8) (2022)
Dan Su, Tatsiana Kosciuk, Hening Lin
Reply to Comment on "Binding Affinity Determines Substrate Specificity and Enables Discovery of substrates for N-Myristoyltransferases". ACS catalysis 12 (15) (2022)
Ananya Anmangandla, Yuxiang Ren, Qin Fu, Sheng Zhang, Hening Lin
The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A. Biochemistry 61 (17) (2022)
Miao Wang, Yugang Zhang, Garrison P Komaniecki, Xuan Lu, Ji Cao, Mingming Zhang, Tao Yu, Dan Hou, Nicole A Spiegelman, Ming Yang, Ian R Price, Hening Lin
Golgi stress induces SIRT2 to counteract Shigella infection via defatty-acylation. Nature communications 13 (1) (2022)
Jialin Shang, Michael R Smith, Ananya Anmangandla, Hening Lin
NAD+-consuming enzymes in immune defense against viral infection. The Biochemical journal 478 (23) (2021)
Yashira L Negrón Abril, Irma R Fernandez, Jun Young Hong, Ying-Ling Chiang, Dennis A Kutateladze, Qingjie Zhao, Min Yang, Jing Hu, Sushabhan Sadhukhan, Bo Li, Bin He, Brenna Remick, Jessica Jingyi Bai, James Mullmann, Fangyu Wang, Viviana Maymi, Ravi Dhawan, Johan Auwerx, Teresa Southard, Richard A Cerione, Hening Lin, Robert Samuel Weiss
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene 40 (9) (2021)
Jun Young Hong, Martin Ian P Malgapo, Yinong Liu, Min Yang, Chengliang Zhu, Xiaoyu Zhang, Patricia Tolbert, Maurine E Linder, Hening Lin
High-Throughput Enzyme Assay for Screening Inhibitors of the ZDHHC3/7/20 Acyltransferases. ACS chemical biology 16 (8) (2021)
Yugang Zhang, Dan Su, Boris Dzikovski, Sean H Majer, Rachael E Coleman, Sidddarth Chandrasekaran, Michael K Fenwick, Brian R Crane, Kyle M Lancaster, Jack H Freed, Hening Lin
Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2. Journal of the American Chemical Society 143 (25) (2021)
Jun Young Hong, Irma Fernandez, Ananya Anmangandla, Xuan Lu, Jessica Jingyi Bai, Hening Lin
Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1-3 Inhibitors. ACS chemical biology 16 (7) (2021)
Zhuoxian Cao, Fenfen Yang, Jie Wang, Zhicheng Gu, Shuxian Lin, Pan Wang, Jianxiong An, Ting Liu, Yan Li, Yongjun Li, Hening Lin, Yong-Long Zhao, Bin He
Indirubin Derivatives as Dual Inhibitors Targeting Cyclin-Dependent Kinase and Histone Deacetylase for Treating Cancer. Journal of medicinal chemistry 64 (20) (2021)
Yugang Zhang, Zhewang Lin, Julia Zhu, Miao Wang, Hening Lin
Diphthamide promotes TOR signaling by increasing the translation of proteins in the TORC1 pathway. Proceedings of the National Academy of Sciences of the United States of America 118 (37) (2021)
Jun Young Hong, Martin Ian P Malgapo, Yinong Liu, Min Yang, Chengliang Zhu, Xiaoyu Zhang, Patricia Tolbert, Maurine E Linder, Hening Lin
Correction to "High-Throughput Enzyme Assay for Screening Inhibitors of the ZDHHC3/7/20 Acyltransferases". ACS chemical biology 16 (11) (2021)
Dan Su, Tatsiana Kosciuk, Min Yang, Ian R Price, Hening Lin
Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases. ACS catalysis 11 (24) (2021)
Hening Lin
Protein cysteine palmitoylation in immunity and inflammation. The FEBS journal (2021)
Zhuoxian Cao, Zhicheng Gu, Shuxian Lin, Di Chen, Jie Wang, Yonglong Zhao, Yan Li, Ting Liu, Yongjun Li, Yi Wang, Hening Lin, Bin He
Attenuation of NLRP3 Inflammasome Activation by Indirubin-Derived PROTAC Targeting HDAC6. ACS chemical biology (2021)
Tatsiana Kosciuk, Hening Lin
N-Myristoyltransferase as a Glycine and Lysine Myristoyltransferase in Cancer, Immunity, and Infections. ACS chemical biology 15 (7) (2020)
David Bi, Jie Yang, Jun Young Hong, Prashit Parikh, Nicole Hinds, Joseph Infanti, Hening Lin, Brian P Weiser
Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene. Biochemistry 59 (40) (2020)
Mingming Zhang, Lixing Zhou, Yuejie Xu, Min Yang, Yilai Xu, Garrison Paul Komaniecki, Tatsiana Kosciuk, Xiao Chen, Xuan Lu, Xiaoping Zou, Maurine E Linder, Hening Lin
A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis. Nature 586 (7829) (2020)
Se In Son, Dan Su, Thanh Tu Ho, Hening Lin
Garcinol Is an HDAC11 Inhibitor. ACS chemical biology 15 (11) (2020)
Lu Zhang, Ji Cao, Longying Dong, Hening Lin
TiPARP forms nuclear condensates to degrade HIF-1α and suppress tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America 117 (24) (2020)
Tatsiana Kosciuk, Ian R Price, Xiaoyu Zhang, Chengliang Zhu, Kayla N Johnson, Shuai Zhang, Steve L Halaby, Garrison P Komaniecki, Min Yang, Caroline J DeHart, Paul M Thomas, Michael P Snyder, J Christopher Fromme, Hening Lin
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature communications 11 (1) (2020)
Kevin Wielenberg, Miao Wang, Min Yang, Abdullah Ozer, John T Lis, Hening Lin
An improved 4'-aminomethyltrioxsalen-based nucleic acid crosslinker for biotinylation of double-stranded DNA or RNA. RSC advances 10 (65) (2020)
Michael K Fenwick, Dan Su, Min Dong, Hening Lin, Steven E Ealick
Structural Basis of the Substrate Selectivity of Viperin. Biochemistry 59 (5) (2020)
Yugang Zhang, Miao Wang, Hening Lin
A Regulatory Cysteine Residue Mediates Reversible Inactivation of NAD+-Dependent Aldehyde Dehydrogenases to Promote Oxidative Stress Response. ACS chemical biology 15 (1) (2019)
Ali Sohail Farooqi, Jun Young Hong, Ji Cao, Xuan Lu, Ian Robert Price, Qingjie Zhao, Tatsiana Kosciuk, Min Yang, Jessica Jingyi Bai, Hening Lin
Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model. Journal of medicinal chemistry 62 (8) (2019)
Nicole A Spiegelman, Jun Young Hong, Jing Hu, Hui Jing, Miao Wang, Ian R Price, Ji Cao, Min Yang, Xiaoyu Zhang, Hening Lin
A Small-Molecule SIRT2 Inhibitor That Promotes K-Ras4a Lysine Fatty-Acylation. ChemMedChem 14 (7) (2019)
Se In Son, Ji Cao, Cheng-Liang Zhu, Seth P Miller, Hening Lin
Activity-Guided Design of HDAC11-Specific Inhibitors. ACS chemical biology 14 (7) (2019)
Hening Lin, Kate S Caroll
Introduction: Posttranslational Protein Modification. Chemical reviews 118 (3) (2019)
Jun Young Hong, Ian Robert Price, Jessica Jingyi Bai, Hening Lin
A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. ACS chemical biology 14 (8) (2019)
Kai Su Greene, Michael J Lukey, Xueying Wang, Bryant Blank, Joseph E Druso, Miao-Chong Joy Lin, Clint A Stalnecker, Chengliang Zhang, Yashira Negrón Abril, Jon W Erickson, Kristin F Wilson, Hening Lin, Robert S Weiss, Richard A Cerione
SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America (2019)
Min Dong, Emily E Dando, Ilana Kotliar, Xiaoyang Su, Boris Dzikovski, Jack H Freed, Hening Lin
The asymmetric function of Dph1-Dph2 heterodimer in diphthamide biosynthesis. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 24 (6) (2019)
Wesley Wei Wang, Maria Angulo-Ibanez, Jie Lyu, Yadagiri Kurra, Zhen Tong, Bo Wu, Ling Zhang, Vangmayee Sharma, Jennifer Zhou, Hening Lin, Yi Qin Gao, Wei Li, Katrin F Chua, Wenshe Ray Liu
A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. Journal of the American Chemical Society 141 (6) (2019)
Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Weishan Huang, Edward Seto, Hening Lin
HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2. Proceedings of the National Academy of Sciences of the United States of America 116 (12) (2019)
Nicole A Spiegelman, Xiaoyu Zhang, Hui Jing, Ji Cao, Ilana B Kotliar, Pornpun Aramsangtienchai, Miao Wang, Zhen Tong, Kelly M Rosch, Hening Lin
SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration. ACS chemical biology 14 (9) (2019)
Michael K Fenwick, Min Dong, Hening Lin, Steven E Ealick
The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis. Biochemistry 58 (43) (2019)
Hong Jiang, Xiaoyu Zhang, Xiao Chen, Pornpun Aramsangtienchai, Zhen Tong, Hening Lin
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies. Chemical reviews 118 (3) (2018)
Yugang Zhang, Zhewang Lin, Miao Wang, Hening Lin
Selective Usage of Isozymes for Stress Response. ACS chemical biology 13 (11) (2018)
Min Dong, Venkatesan Kathiresan, Michael K Fenwick, Andrew T Torelli, Yang Zhang, Jonathan D Caranto, Boris Dzikovski, Ajay Sharma, Kyle M Lancaster, Jack H Freed, Steven E Ealick, Brian M Hoffman, Hening Lin
Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science (New York, N.Y.) 359 (6381) (2018)
Min Dong, Yugang Zhang, Hening Lin
Noncanonical Radical SAM Enzyme Chemistry Learned from Diphthamide Biosynthesis. Biochemistry 57 (25) (2018)
Nicole A Spiegelman, Ian R Price, Hui Jing, Miao Wang, Min Yang, Ji Cao, Jun Young Hong, Xiaoyu Zhang, Pornpun Aramsangtienchai, Sushabhan Sadhukhan, Hening Lin
Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity-Dependent Inhibition, and On-Target Anticancer Activities. ChemMedChem 13 (18) (2018)
Min Dong, Masaki Horitani, Boris Dzikovski, Jack H Freed, Steven E Ealick, Brian M Hoffman, Hening Lin
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis. Journal of the American Chemical Society 139 (16) (2017)
Robert J MacDonald, Jonathan H Shrimp, Hong Jiang, Lu Zhang, Hening Lin, Andrew Yen
Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout. Scientific reports 7 (1) (2017)

Hening Lin.css-eqlu8i{font-size:small;padding-left:4px;} (H Lin)

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Hening Lin (H Lin)