Andrew O M Wilkie (Chao Lu)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 25

Top Topics

Duchenne Muscular Dystrophy

Pluripotent Stem Cells

Dna Methylation

Muscle Invasive Bladder Cancer

Top Venues

Nature communications

Science advances

Nature genetics

Cancer research communications

This page only lists publications with an associated author ORCID identifier.

Publications

Sakina A Plumber, Tiffany Tate, Hikmat A Al-Ahmadie, Xiao Chen, Woonyoung Choi, Merve Basar, Andrew O M Wilkie, Aaron D Viny, Ekatherina Batourina, Jiaqi Li, Kristjan H Gretarsson, Besmira Alija, Andrei Molotkov, Gregory Wiessner, Byron Hing Lung Lee, James McKiernan, David J McConkey, Colin Dinney, Bogdan A Czerniak, Cathy Lee Mendelsohn
Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nature communications 15 (1) (2024)
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Vishnu Udayakumar Sunitha Kumary, Allison R Hickman, Varun Sahu, Rachel Lee, Xinjing Xu, Natalie Lipieta, Samuel P Flashner, Oluwatobi A Adeleke, Irina K Popova, Hailey F Taylor, Kelsey E Noll, Carolina Lin Windham, Danielle N Maryanski, Bryan J Venters, Hiroshi Nakagawa, Michael-Christopher Keogh, Karim-Jean Armache, Andrew O M Wilkie
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science advances 10 (35) (2024)
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Vishnu Udayakumar Sunitha Kumary, Allison R Hickman, Varun Sahu, Rachel Lee, Xinjing Xu, Natalie Lipieta, Samuel P Flashner, Oluwatobi A Adeleke, Irina K Popova, Hailey F Taylor, Kelsey E Noll, Carolina Lin Windham, Danielle N Maryanski, Bryan J Venters, Hiroshi Nakagawa, Michael-Christopher Keogh, Karim-Jean Armache, Andrew O M Wilkie
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science advances 10 (35) (2024)
Sakina A Plumber, Tiffany Tate, Hikmat A Al-Ahmadie, Xiao Chen, Woonyoung Choi, Merve Basar, Andrew O M Wilkie, Aaron D Viny, Ekatherina Batourina, Jiaqi Li, Kristjan H Gretarsson, Besmira Alija, Andrei Molotkov, Gregory Wiessner, Byron Hing Lung Lee, James McKiernan, David J McConkey, Colin Dinney, Bogdan A Czerniak, Cathy Lee Mendelsohn
Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nature communications 15 (1) (2024)
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Vishnu Udayakumar Sunitha Kumary, Allison R Hickman, Varun Sahu, Rachel Lee, Xinjing Xu, Natalie Lipieta, Samuel P Flashner, Oluwatobi A Adeleke, Irina K Popova, Hailey F Taylor, Kelsey E Noll, Carolina Lin Windham, Danielle N Maryanski, Bryan J Venters, Hiroshi Nakagawa, Michael-Christopher Keogh, Karim-Jean Armache, Andrew O M Wilkie
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science advances 10 (35) (2024)
Sakina A Plumber, Tiffany Tate, Hikmat A Al-Ahmadie, Xiao Chen, Woonyoung Choi, Merve Basar, Andrew O M Wilkie, Aaron D Viny, Ekatherina Batourina, Jiaqi Li, Kristjan H Gretarsson, Besmira Alija, Andrei Molotkov, Gregory Wiessner, Byron Hing Lung Lee, James McKiernan, David J McConkey, Colin Dinney, Bogdan A Czerniak, Cathy Lee Mendelsohn
Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nature communications 15 (1) (2024)
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Vishnu Udayakumar Sunitha Kumary, Allison R Hickman, Varun Sahu, Rachel Lee, Xinjing Xu, Natalie Lipieta, Samuel P Flashner, Oluwatobi A Adeleke, Irina K Popova, Hailey F Taylor, Kelsey E Noll, Carolina Lin Windham, Danielle N Maryanski, Bryan J Venters, Hiroshi Nakagawa, Michael-Christopher Keogh, Karim-Jean Armache, Andrew O M Wilkie
Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch. Science advances 10 (35) (2024)
Xiao Chen, Yinglu Li, Fang Zhu, Xinjing Xu, Brian Estrella, Manuel A Pazos, John T McGuire, Dimitris Karagiannis, Varun Sahu, Mustafo Mustafokulov, Claudio Scuoppo, Francisco J Sánchez Rivera, Yadira M Soto-Feliciano, Laura Pasqualucci, Alberto Ciccia, Jennifer Effie Amengual, Andrew O M Wilkie
Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma. Nature communications 14 (1) (2023)
Zhiming Li, Shoufu Duan, Xu Hua, Xiaowei Xu, Yinglu Li, Demis Menolfi, Hui Zhou, Andrew O M Wilkie, Shan Zha, Stephen P Goff, Zhiguo Zhang
Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements. Nature (2023)
Ping Chi, Peter W Lewis, Andrew O M Wilkie, Janice Lu, Alexander J Ruthenburg, Benjamin R Sabari, David Shechter, Liling Wan, Gang Greg Wang
Charles David Allis (1951-2023). Nature genetics (2023)
Gizem Efe, Karen J Dunbar, Kensuke Sugiura, Katherine Cunningham, Saul Carcamo, Spyros Karaiskos, Qiaosi Tang, Ricardo Cruz-Acuna, Lois Resnick-Silverman, Jessica Peura, Andrew O M Wilkie, Dan Hasson, Andres J Klein-Szanto, Alison M Taylor, James J Manfredi, Carol Prives, Anil K Rustgi
p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression. Cancer discovery (2023)
Josephine Kam Tai K Dermawan, Khedoujia Nafa, Abhinita Mohanty, Yingjuan Xu, Ivelise Rijo, Jacklyn Casanova, Liliana B Villafania, Jamal K Benhamida, Ciara M Kelly, William D Tap, Patrick J Boland, Nicola Fabbri, John H Healey, Marc Ladanyi, Andrew O M Wilkie, Meera R Hameed
Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma. Cancer research communications 3 (3) (2023)
Josephine Kam Tai K Dermawan, Khedoujia Nafa, Abhinita Mohanty, Yingjuan Xu, Ivelise Rijo, Jacklyn Casanova, Liliana B Villafania, Jamal K Benhamida, Ciara M Kelly, William D Tap, Patrick J Boland, Nicola Fabbri, John H Healey, Marc Ladanyi, Andrew O M Wilkie, Meera R Hameed
Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma. Cancer research communications 3 (3) (2023)
Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan H Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey F Taylor, Zu-Wen Sun, Ryan J Ezell, Anup Vaidya, Matthew J Meiners, Marcus A Cheek, William J Rice, Vladimir Svetlov, Evgeny Nudler, Andrew O M Wilkie, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Science advances 9 (32) (2023)
Kehan Bao, Chun-Min Shan, Xiao Chen, Gulzhan Raiymbek, Jeremy G Monroe, Yimeng Fang, Takenori Toda, Kristin D Koutmou, Kaushik Ragunathan, Andrew O M Wilkie, Luke E Berchowitz, Songtao Jia
The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly. PLoS genetics 18 (2) (2022)
Daniel N Weinberg, Phillip Rosenbaum, Xiao Chen, Douglas Barrows, Cynthia Horth, Matthew R Marunde, Irina K Popova, Zachary B Gillespie, Michael-Christopher Keogh, Andrew O M Wilkie, Jacek Majewski, C David Allis
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands. Nature genetics 53 (6) (2021)
Yinglu Li, Xiao Chen, Andrew O M Wilkie
The interplay between DNA and histone methylation: molecular mechanisms and disease implications. EMBO reports 22 (5) (2021)
Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan R Sweha, Siva Kumar Natarajan, Matthew Pun, Jill Bayliss, Martin P Ogrodzinski, Sriram Venneti, Brendan Mullan, Debra Hawes, Fusheng Yang, Andrew O M Wilkie, Benjamin R Sabari, Abhinav Achreja, Jin Heon Jeon, Olamide Animasahun, Marcin Cieslik, Christopher Dunham, Stephen Yip, Juliette Hukin, Joanna J Phillips, Miriam Bornhorst, Andrea M Griesinger, Andrew M Donson, Nicholas K Foreman, Hugh J L Garton, Jason Heth, Karin Muraszko, Javad Nazarian, Carl Koschmann, Li Jiang, Mariella G Filbin, Deepak Nagrath, Marcel Kool, Andrey Korshunov, Stefan M Pfister, Richard J Gilbertson, C David Allis, Arul M Chinnaiyan, Sophia Y Lunt, Stefan Bluml, Alexander R Judkins, Sriram Venneti
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas. Science translational medicine 13 (614) (2021)
Tiffany Tate, Tina Xiang, Sarah E Wobker, Mi Zhou, Xiao Chen, Hyunwoo Kim, Ekatherina Batourina, Chyuan-Sheng Lin, William Y Kim, Andrew O M Wilkie, James M Mckiernan, Cathy Lee Mendelsohn
Pparg signaling controls bladder cancer subtype and immune exclusion. Nature communications 12 (1) (2021)
Chang Liu, Tiffany Tate, Ekatherina Batourina, Steven T Truschel, S Steven Potter, Mike Adam, Tina Xiang, Martin Picard, Maia Reiley, Kerry Schneider, Manuel Tamargo, Andrew O M Wilkie, Xiao Chen, Jing He, Hyunwoo Kim, Cathy Lee Mendelsohn
Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nature communications 10 (1) (2019)
Munemasa Mori, Kazuhiro Furuhashi, Jennifer A Danielsson, Yuichi Hirata, Miwako Kakiuchi, Chyuan-Sheng Lin, Mayu Ohta, Paul Riccio, Yusuke Takahashi, Xinjing Xu, Charles W Emala, Andrew O M Wilkie, Hiromitsu Nakauchi, Wellington V Cardoso
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. Nature medicine 25 (11) (2019)
Ashot S Harutyunyan, Brian Krug, Haifen Chen, Simon Papillon-Cavanagh, Michele Zeinieh, Nicolas De Jay, Shriya Deshmukh, Carol C L Chen, Jad Belle, Leonie G Mikael, Dylan M Marchione, Rui Li, Hamid Nikbakht, Bo Hu, Gael Cagnone, Warren A Cheung, Abdulshakour Mohammadnia, Denise Bechet, Damien Faury, Melissa K McConechy, Manav Pathania, Siddhant U Jain, Benjamin Ellezam, Alexander G Weil, Alexandre Montpetit, Paolo Salomoni, Tomi Pastinen, Andrew O M Wilkie, Peter W Lewis, Benjamin A Garcia, Claudia L Kleinman, Nada Jabado, Jacek Majewski
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nature communications 10 (1) (2019)
Andrew O M Wilkie, C David Allis
SWI/SNF complex in cancer. Nature genetics 49 (2) (2017)
Andrew O M Wilkie
Many faces of SMCHD1. Nature genetics 49 (2) (2017)
Simon Papillon-Cavanagh, Andrew O M Wilkie, Tenzin Gayden, Leonie G Mikael, Denise Bechet, Christina Karamboulas, Laurie Ailles, Jason Karamchandani, Dylan M Marchione, Benjamin A Garcia, Ilan Weinreb, David Goldstein, Peter W Lewis, Octavia Maria Dancu, Sandeep Dhaliwal, William Stecho, Christopher J Howlett, Joe S Mymryk, John W Barrett, Anthony Charles Nichols, C David Allis, Jacek Majewski, Nada Jabado
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas. Nature genetics 49 (2) (2017)