Charles Nicholas Serhan (Charles N Serhan)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 53

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Proceedings of the National Academy of Sciences of the United States of America

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Arteriosclerosis, thrombosis, and vascular biology

Brigham and Women's Hospital-Harvard Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Brigham and Women's Hospital-Harvard Medical School Jul 01 1986

United States

Professor and Center Director :: CET&RI, Anesthesia, Perioperative and Pain Medicine

Publications

Rosangela Akemi Hoshi, Mona Alotaibi, Yanyan Liu, Jeramie D Watrous, Paul M Ridker, Robert J Glynn, Charles Nicholas Serhan, Heike Luttmann-Gibson, M Vinayaga Moorthy, Mohit Jain, Demler V Olga, Samia Mora
One-Year Effects of High-Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial. Arteriosclerosis, thrombosis, and vascular biology 44 (7) (2024)
Rosangela Akemi Hoshi, Mona Alotaibi, Yanyan Liu, Jeramie D Watrous, Paul M Ridker, Robert J Glynn, Charles Nicholas Serhan, Heike Luttmann-Gibson, M Vinayaga Moorthy, Mohit Jain, Demler V Olga, Samia Mora
One-Year Effects of High-Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial. Arteriosclerosis, thrombosis, and vascular biology 44 (7) (2024)
Rosangela Akemi Hoshi, Mona Alotaibi, Yanyan Liu, Jeramie D Watrous, Paul M Ridker, Robert J Glynn, Charles Nicholas Serhan, Heike Luttmann-Gibson, M Vinayaga Moorthy, Mohit Jain, Demler V Olga, Samia Mora
One-Year Effects of High-Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial. Arteriosclerosis, thrombosis, and vascular biology 44 (7) (2024)
Hong Yong Peh, Robert Nshimiyimana, Thayse R Brüggemann, Melody G Duvall, Julie Nijmeh, Charles Nicholas Serhan, Bruce David Levy
15-epi-lipoxin A 5 promotes neutrophil exit from exudates for clearance by splenic macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (14) (2024)
Charles Nicholas Serhan, Nan Chiang, Robert Nshimiyimana
Low-dose pro-resolving mediators temporally reset the resolution response to microbial inflammation. Molecular medicine (Cambridge, Mass.) 30 (1) (2024)
Simona Pace, Katharina Paula Lydia Meyer, Fabiana Troisi, Rossella Bilancia, Danilo D'Avino, Olga Parisi, Roberta Rizza, Paola Stiuso, Jana Gerstmeier, Patrick Schädel, Armando Ialenti, Lidia Sautebin, Charles Nicholas Serhan, Antonietta Rossi, Francesca Borrelli, Oliver Werz
Sex hormone deprivation abolishes sex-specific differences in murine colon inflammation and related lipid mediator production. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (14) (2024)
Hong Yong Peh, Robert Nshimiyimana, Thayse R Brüggemann, Melody G Duvall, Julie Nijmeh, Charles Nicholas Serhan, Bruce David Levy
15-epi-lipoxin A 5 promotes neutrophil exit from exudates for clearance by splenic macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (14) (2024)
Hong Yong Peh, Robert Nshimiyimana, Thayse R Brüggemann, Melody G Duvall, Julie Nijmeh, Charles Nicholas Serhan, Bruce David Levy
15-epi-lipoxin A 5 promotes neutrophil exit from exudates for clearance by splenic macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (14) (2024)
Robert Nshimiyimana, Mélissa Simard, Tarvi Teder, Ana R Rodriguez, Bernd W Spur, Jesper Z Haeggström, Charles Nicholas Serhan
Biosynthesis of resolvin D1, resolvin D2, and RCTR1 from 7,8(S,S)-epoxytetraene in human neutrophils and macrophages. Proceedings of the National Academy of Sciences of the United States of America 121 (37) (2024)
Simona Pace, Katharina Paula Lydia Meyer, Fabiana Troisi, Rossella Bilancia, Danilo D'Avino, Olga Parisi, Roberta Rizza, Paola Stiuso, Jana Gerstmeier, Patrick Schädel, Armando Ialenti, Lidia Sautebin, Charles Nicholas Serhan, Antonietta Rossi, Francesca Borrelli, Oliver Werz
Sex hormone deprivation abolishes sex-specific differences in murine colon inflammation and related lipid mediator production. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 38 (14) (2024)
Gabrielle Fredman, Charles Nicholas Serhan
Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease. Nature reviews. Cardiology (2024)
Rosangela Akemi Hoshi, Mona Alotaibi, Yanyan Liu, Jeramie D Watrous, Paul M Ridker, Robert J Glynn, Charles Nicholas Serhan, Heike Luttmann-Gibson, M Vinayaga Moorthy, Mohit Jain, Demler V Olga, Samia Mora
One-Year Effects of High-Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial. Arteriosclerosis, thrombosis, and vascular biology (2024)
Rosangela Akemi Hoshi, Mona Alotaibi, Yanyan Liu, Jeramie D Watrous, Paul M Ridker, Robert J Glynn, Charles Nicholas Serhan, Heike Luttmann-Gibson, M Vinayaga Moorthy, Mohit Jain, Demler V Olga, Samia Mora
One-Year Effects of High-Intensity Statin on Bioactive Lipids: Findings From the JUPITER Trial. Arteriosclerosis, thrombosis, and vascular biology (2024)
Robert Nshimiyimana, Stephania Libreros, Mélissa Simard, Nan Chiang, Ana R Rodriguez, Bernd W Spur, Jesper Z Haeggström, Charles Nicholas Serhan
Stereochemistry and functions of the new cysteinyl-resolvin, 4S,5R-RCTR1, in efferocytosis and erythrophagocytosis of human senescent erythrocytes. American journal of hematology (2023)
Hong Yong Peh, Thayse R Brüggemann, Melody G Duvall, Robert Nshimiyimana, Julie Nijmeh, Maria A Cinelli, Elliot Israel, Charles Nicholas Serhan, Bruce David Levy
Resolvin D2 regulates type 2 inflammatory responses and promotes resolution of mouse allergic inflammation. Allergy (2023)
Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C Norris, Nan Chiang, Charles Nicholas Serhan
Author Correction: Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nature communications 14 (1) (2023)
Zhigang Rao, Elena Brunner, Benjamin Giszas, Aishwarya Iyer-Bierhoff, Jana Gerstmeier, Friedemann Börner, Paul M Jordan, Simona Pace, Katharina Paula Lydia Meyer, Robert Klaus Hofstetter, Daniel Merk, Christian Paulenz, Thorsten Heinzel, Philip C Grunert, Andreas Stallmach, Charles Nicholas Serhan, Markus Werner, Oliver Werz
Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution. Proceedings of the National Academy of Sciences of the United States of America 120 (35) (2023)
Wenjun Li, Hailey M Shepherd, Yuriko Terada, Ashley E Shay, Amit I Bery, Andrew E Gelman, Kory J Lavine, Charles Nicholas Serhan, Daniel Kreisel
Resolvin D1 prevents injurious neutrophil swarming in transplanted lungs. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Vinicius S Nunes, Odonírio Abrahão, Alexandre P Rogério, Charles Nicholas Serhan
ALX/FPR2 Activation by Stereoisomers of D1 Resolvins Elucidating with Molecular Dynamics Simulation. The journal of physical chemistry. B (2023)
Amalie Føreid Reinertsen, Stephania Libreros, Robert Nshimiyimana, Charles Nicholas Serhan, Trond Vidar Hansen
Metabolization of Resolvin E4 by ω-Oxidation in Human Neutrophils: Synthesis and Biological Evaluation of 20-Hydroxy-Resolvin E4 (20-OH-RvE4). ACS pharmacology & translational science 6 (12) (2023)
Stephania Libreros, Robert Nshimiyimana, Brendon Lee, Charles Nicholas Serhan
Infectious Neutrophil deployment is regulated by Resolvin D4. Blood (2023)
Ashley E Shay, Robert Nshimiyimana, Bengt Samuelsson, Nicos A Petasis, Jesper Z Haeggström, Charles Nicholas Serhan
Human leukocytes selectively convert 4 S ,5 S -epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer. Proceedings of the National Academy of Sciences of the United States of America 118 (51) (2022)
Robert Nshimiyimana, Ting Fung Lam, Shubhangi Aggarwal, Charles Nicholas Serhan, Nicos A Petasis
First stereoselective total synthesis of 4( S ),5( S )-oxido-17( S )-hydroxy-6( E ),8( E ),10( Z ),13( Z ),15( E ),19( Z )-docosahexaenoic acid, the biosynthetic precursor of resolvins D3 and D4. RSC advances 12 (19) (2022)
Kenta Furutani, Ou-Yang Chen, Aidan McGinnis, Yuqing Wang, Charles Nicholas Serhan, Trond Vidar Hansen, Ru-Rong Ji
Novel pro-resolving lipid mediator mimetic 3-oxa-PD1n-3 DPA reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice. Pain (2022)
Markus V Olsen, Anne V Lyngstadaas, Jeffrey A Bair, Robin R Hodges, Tor P Utheim, Charles Nicholas Serhan, Darlene A Dartt
Signaling Pathways Used by the Specialized Pro-Resolving Mediator Maresin 2 Regulate Goblet Cell Function: Comparison with Maresin 1. International journal of molecular sciences 23 (11) (2022)
Robert Nshimiyimana, Stephen J Glynn, Charles Nicholas Serhan, Nicos A Petasis
Stereocontrolled total synthesis of Resolvin D4 and 17( R )-Resolvin D4. Organic & biomolecular chemistry (2022)
Menglu Yang, Haakon K Fjærvoll, Ketil A Fjærvoll, Nicholas H Wang, Tor P Utheim, Charles Nicholas Serhan, Darlene A Dartt
Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators. Scientific reports 12 (1) (2022)
Nan Chiang, Miyuki Sakuma, Ana R Rodriguez, Bernd W Spur, Daniel Irima, Charles Nicholas Serhan
Resolvin T-series Reduce Neutrophil Extracellular Traps. Blood (2021)
Nan Chiang, Xavier de la Rosa, Stephania Libreros, Hui Pan, Jonathan M Dreyfuss, Charles Nicholas Serhan
Cysteinyl-specialized proresolving mediators link resolution of infectious inflammation and tissue regeneration via TRAF3 activation. Proceedings of the National Academy of Sciences of the United States of America 118 (10) (2021)
Amalie Føreid Reinertsen, Karoline Gangestad Primdahl, Ashley Elizabeth Shay, Charles Nicholas Serhan, Trond Vidar Hansen, Marius Aursnes
Stereoselective Synthesis and Structural Confirmation of the Specialized Pro-Resolving Mediator Resolvin E4. The Journal of organic chemistry 86 (4) (2021)
Paul C Norris, Stephania Libreros, Charles Nicholas Serhan
Resolution metabolomes activated by hypoxic environment. Science advances 5 (10) (2019)
Molly M Gilligan, Allison Gartung, Megan L Sulciner, Paul C Norris, Vikas P Sukhatme, Diane R Bielenberg, Sui Huang, Mark W Kieran, Charles Nicholas Serhan, Dipak Panigrahy
Aspirin-triggered proresolving mediators stimulate resolution in cancer. Proceedings of the National Academy of Sciences of the United States of America 116 (13) (2019)
Paul C Norris, Ann C Skulas-Ray, Ian Riley, Chesney K Richter, Penny M Kris-Etherton, Gordon L Jensen, Charles Nicholas Serhan, Krishna Rao Maddipati
Author Correction: Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation. Scientific reports 9 (1) (2019)
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D'Amelio, Nicola Biagio Mercuri
Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nature communications 10 (1) (2019)
Yu Zhou, Juan Lei, Qichao Xie, Lei Wu, Shengwei Jin, Bo Guo, Xiang Wang, Guifang Yan, Qi Zhang, Huakan Zhao, Jiangang Zhang, Xiao Zhang, Jingchun Wang, Jiaqi Gu, Xiaoli Liu, Duyun Ye, Hongming Miao, Charles Nicholas Serhan, Yongsheng Li
Fibrinogen-like protein 2 controls sepsis catabasis by interacting with resolvin Dp5. Science advances 5 (11) (2019)
Zhigang Rao, Simona Pace, Paul M Jordan, Rossella Bilancia, Fabiana Troisi, Friedemann Börner, Nico Andreas, Thomas Kamradt, Dirk Menche, Antonietta Rossi, Charles Nicholas Serhan, Jana Gerstmeier, Oliver Werz
Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation. Journal of immunology (Baltimore, Md. : 1950) 203 (4) (2019)
Jiang Yang, Munir M Zaman, Iliyan Vlasakov, Roopali Roy, Lan Huang, Camilia R Martin, Steven D Freedman, Charles Nicholas Serhan, Marsha A Moses
Adipocytes promote ovarian cancer chemoresistance. Scientific reports 9 (1) (2019)
Paraskevi Krashia, Alberto Cordella, Annalisa Nobili, Livia La Barbera, Mauro Federici, Alessandro Leuti, Federica Campanelli, Giuseppina Natale, Gioia Marino, Valeria Calabrese, Francescangelo Vedele, Veronica Ghiglieri, Barbara Picconi, Giulia Di Lazzaro, Tommaso Schirinzi, Giulia Sancesario, Nicolas Casadei, Olaf Riess, Sergio Bernardini, Antonio Pisani, Paolo Calabresi, Maria Teresa Viscomi, Charles Nicholas Serhan, Valerio Chiurchiù, Marcello D'Amelio, Nicola Biagio Mercuri
Author Correction: Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease. Nature communications 10 (1) (2019)
Jamie L Lahvic, Michelle Ammerman, Pulin Li, Megan C Blair, Emma R Stillman, Eva M Fast, Anne L Robertson, Constantina Christodoulou, Julie R Perlin, Song Yang, Nan Chiang, Paul C Norris, Madeleine L Daily, Shelby E Redfield, Iris T Chan, Mona Chatrizeh, Michael E Chase, Olivia Weis, Yi Zhou, Charles Nicholas Serhan, Leonard I Zon
Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132. Proceedings of the National Academy of Sciences of the United States of America 115 (37) (2018)
Oliver Werz, Jana Gerstmeier, Stephania Libreros, Xavier De la Rosa, Markus Werner, Paul C Norris, Nan Chiang, Charles Nicholas Serhan
Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity. Nature communications 9 (1) (2018)
Charles Nicholas Serhan, Xavier de la Rosa, Charlotte C Jouvene
Cutting Edge: Human Vagus Produces Specialized Proresolving Mediators of Inflammation with Electrical Stimulation Reducing Proinflammatory Eicosanoids. Journal of immunology (Baltimore, Md. : 1950) 201 (11) (2018)
Alessandro Matte, Antonio Recchiuti, Enrica Federti, Bérengère Koehl, Thomas Mintz, Wassim El Nemer, Pierre-Louis Tharaux, Valentine Brousse, Immacolata Andolfo, Alessia Lamolinara, Olga Weinberg, Angela Siciliano, Paul C Norris, Ian R Riley, Achille Iolascon, Charles Nicholas Serhan, Carlo Brugnara, Lucia De Franceschi
Resolution of sickle cell disease-associated inflammation and tissue damage with 17R-resolvin D1. Blood 133 (3) (2018)
Ho Pan Sham, Katherine H Walker, Raja-Elie E Abdulnour, Nandini Krishnamoorthy, David N Douda, Paul C Norris, Ioanna Barkas, Sarah Benito-Figueroa, Jennifer K Colby, Charles Nicholas Serhan, Bruce D Levy
15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-κB Regulators in Bacterial Pneumonia. Journal of immunology (Baltimore, Md. : 1950) 200 (8) (2018)
Ganesh V Halade, Paul C Norris, Vasundhara Kain, Charles Nicholas Serhan, Kevin A Ingle
Splenic leukocytes define the resolution of inflammation in heart failure. Science signaling 11 (520) (2018)
Jørn Eivind Tungen, Lisa Gerstmann, Anders Vik, Roberta De Matteis, Romain Alexandre Colas, Jesmond Dalli, Nan Chiang, Charles Nicholas Serhan, Markus Kalesse, Trond Vidar Hansen
Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (6) (2018)
Paul C Norris, Ann C Skulas-Ray, Ian Riley, Chesney K Richter, Penny M Kris-Etherton, Gordon L Jensen, Charles Nicholas Serhan, Krishna Rao Maddipati
Identification of specialized pro-resolving mediator clusters from healthy adults after intravenous low-dose endotoxin and omega-3 supplementation: a methodological validation. Scientific reports 8 (1) (2018)
Jesmond Dalli, Charles Nicholas Serhan
Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology. British journal of pharmacology 176 (8) (2018)
Paul C Norris, Stephania Libreros, Nan Chiang, Charles Nicholas Serhan
A cluster of immunoresolvents links coagulation to innate host defense in human blood. Science signaling 10 (490) (2017)
Megan L Sulciner, Charles Nicholas Serhan, Molly M Gilligan, Dayna K Mudge, Jaimie Chang, Allison Gartung, Kristen A Lehner, Diane R Bielenberg, Birgitta Schmidt, Jesmond Dalli, Emily R Greene, Yael Gus-Brautbar, Julia Piwowarski, Tadanori Mammoto, David Zurakowski, Mauro Perretti, Vikas P Sukhatme, Arja Kaipainen, Mark W Kieran, Sui Huang, Dipak Panigrahy
Resolvins suppress tumor growth and enhance cancer therapy. The Journal of experimental medicine 215 (1) (2017)
Esther Titos, Bibiana Rius, Cristina López-Vicario, José Alcaraz-Quiles, Verónica García-Alonso, Aritz Lopategi, Jesmond Dalli, Juan José Lozano, Vicente Arroyo, Salvadora Delgado, Charles Nicholas Serhan, Joan Claria
Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. Journal of immunology (Baltimore, Md. : 1950) 197 (8) (2016)
Romain A Colas, Jesmond Dalli, Nan Chiang, Iliyan Vlasakov, Julia M Sanger, Ian R Riley, Charles Nicholas Serhan
Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation. Journal of immunology (Baltimore, Md. : 1950) 197 (11) (2016)
Marcelo O Freire, Jesmond Dalli, Charles Nicholas Serhan, Thomas E Van Dyke
Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes. Journal of immunology (Baltimore, Md. : 1950) 198 (2) (2016)
Hildur H Arnardottir, Jesmond Dalli, Lucy Victoria Norling, Romain A Colas, Mauro Perretti, Charles Nicholas Serhan
Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. Journal of immunology (Baltimore, Md. : 1950) 197 (6) (2016)

Charles Nicholas Serhan.css-eqlu8i{font-size:small;padding-left:4px;} (Charles N Serhan)

Publication Activity (10 Years)

Top Topics

Top Venues

Charles Nicholas Serhan (Charles N Serhan)