Christiane Schaffitzel (C Schaffitzel)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 36

Top Venues

Nucleic acids research

Acta crystallographica. Section D, Structural biology

Toxins

Science advances

University of Bristol

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Bristol Jun 15 2014

United Kingdom

Professor of Biochemistry :: Faculty of Life Sciences, School of Biochemistry

European Molecular Biology Laboratory Dec 01 2007 - Nov 30 2016

France

Team Leader :: Grenoble Outstation

ETH Zürich Jan 01 2006 - Nov 30 2007

Switzerland

Oberassistent/ Lecturer :: Institute of Molecular Biology and Biophysics (IMB)

ETH Zürich Aug 01 2001 - Dec 31 2005

Switzerland

Postdoctoral Fellow :: Institute of Molecular Biology and Biophysics (IMB)

Publications

Julien Capin, Alexandra Harrison, Renata A Raele, Sathish K N Yadav, Dominique Baiwir, Gabriel Mazzucchelli, Loic Quinton, Timothy J Satchwell, Ashley M Toye, Christiane Schaffitzel, Imre Berger, Francesco Aulicino
An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing. Nucleic acids research 52 (6) (2024)
Julien Capin, Alexandra Harrison, Renata A Raele, Sathish K N Yadav, Dominique Baiwir, Gabriel Mazzucchelli, Loic Quinton, Timothy J Satchwell, Ashley M Toye, Christiane Schaffitzel, Imre Berger, Francesco Aulicino
An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing. Nucleic acids research 52 (6) (2024)
Julien Capin, Alexandra Harrison, Renata A Raele, Sathish K N Yadav, Dominique Baiwir, Gabriel Mazzucchelli, Loic Quinton, Timothy J Satchwell, Ashley M Toye, Christiane Schaffitzel, Imre Berger, Francesco Aulicino
An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing. Nucleic acids research (2024)
Julien Capin, Alexandra Harrison, Renata A Raele, Sathish K N Yadav, Dominique Baiwir, Gabriel Mazzucchelli, Loic Quinton, Timothy J Satchwell, Ashley M Toye, Christiane Schaffitzel, Imre Berger, Francesco Aulicino
An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing. Nucleic acids research 52 (6) (2024)
Stefanie K Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso, Camille Abada, Thomas Crasset, Fabien Durbesson, Rebecca J Edge, Priscila El-Kazzi, Sophie Hall, Damien Redureau, Richard Stenner, Johara Boldrini-França, Huan Sun, António Roldão, Paula M Alves, Robert A Harrison, Renaud Vincentelli, Imre Berger, Loïc Quinton, Nicholas R Casewell, Christiane Schaffitzel
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming. Toxins 15 (12) (2023)
Christine Toelzer, Kapil Gupta, Imre Berger, Christiane Schaffitzel
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. Acta crystallographica. Section D, Structural biology 79 (Pt 2) (2023)
George H Hutchins, Claire E M Noble, H Adrian Bunzel, Christopher Williams, Paulina Dubiel, Sathish K N Yadav, Paul M Molinaro, Rob Barringer, Hector Blackburn, Benjamin J Hardy, Alice E Parnell, Charles Landau, Paul R Race, Thomas A A Oliver, Ronald L Koder, Matthew P Crump, Christiane Schaffitzel, Ana Sofia F Oliveira, Adrian J Mulholland, John Leslie Ross Anderson
An expandable, modular de novo protein platform for precision redox engineering. Proceedings of the National Academy of Sciences of the United States of America 120 (31) (2023)
Srinjan Basu, O Shukron, Dominic Hall, Pierre Parutto, Aleks Ponjavic, D Shah, W Boucher, David Lando, W Zhang, N Reynolds, L H Sober, A Jartseva, Ramy Ragheb, X Ma, Julie Cramard, R Floyd, J Balmer, T A Drury, A R Carr, Lisa-Maria Needham, A Aubert, G Communie, K Gor, M Steindel, Lluis Morey, Enrique Blanco, Till Bartke, Luciano Di Croce, Imre Berger, Christiane Schaffitzel, Steven F Lee, Tim J Stevens, David Klenerman, Brian Hendrich, David Holcman, Ernest D Laue
Publisher Correction: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD. Nature structural & molecular biology (2023)
Srinjan Basu, O Shukron, Dominic Hall, Pierre Parutto, Aleks Ponjavic, D Shah, W Boucher, David Lando, W Zhang, N Reynolds, L H Sober, A Jartseva, Ramy Ragheb, X Ma, Julie Cramard, R Floyd, J Balmer, T A Drury, A R Carr, Lisa-Maria Needham, A Aubert, G Communie, K Gor, M Steindel, Lluis Morey, Enrique Blanco, Till Bartke, Luciano Di Croce, Imre Berger, Christiane Schaffitzel, Steven F Lee, Tim J Stevens, David Klenerman, Brian Hendrich, David Holcman, Ernest D Laue
Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD. Nature structural & molecular biology (2023)
Christine Toelzer, Kapil Gupta, Imre Berger, Christiane Schaffitzel
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. Acta crystallographica. Section D, Structural biology 79 (Pt 2) (2023)
Stefanie K Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso, Camille Abada, Thomas Crasset, Fabien Durbesson, Rebecca J Edge, Priscila El-Kazzi, Sophie Hall, Damien Redureau, Richard Stenner, Johara Boldrini-França, Huan Sun, António Roldão, Paula M Alves, Robert A Harrison, Renaud Vincentelli, Imre Berger, Loïc Quinton, Nicholas R Casewell, Christiane Schaffitzel
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming. Toxins 15 (12) (2023)
Stefanie K Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso, Camille Abada, Thomas Crasset, Fabien Durbesson, Rebecca J Edge, Priscila El-Kazzi, Sophie Hall, Damien Redureau, Richard Stenner, Johara Boldrini-França, Huan Sun, António Roldão, Paula M Alves, Robert A Harrison, Renaud Vincentelli, Imre Berger, Loïc Quinton, Nicholas R Casewell, Christiane Schaffitzel
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming. Toxins 15 (12) (2023)
Stefanie K Menzies, Raquel Arinto-Garcia, Fernanda Gobbi Amorim, Iara Aimê Cardoso, Camille Abada, Thomas Crasset, Fabien Durbesson, Rebecca J Edge, Priscila El-Kazzi, Sophie Hall, Damien Redureau, Richard Stenner, Johara Boldrini-França, Huan Sun, António Roldão, Paula M Alves, Robert A Harrison, Renaud Vincentelli, Imre Berger, Loïc Quinton, Nicholas R Casewell, Christiane Schaffitzel
ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming. Toxins 15 (12) (2023)
Christine Toelzer, Kapil Gupta, Imre Berger, Christiane Schaffitzel
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. Acta crystallographica. Section D, Structural biology 79 (Pt 2) (2023)
Lingling Sun, Justine Mailliot, Christiane Schaffitzel
Nonsense-Mediated mRNA Decay Factor Functions in Human Health and Disease. Biomedicines 11 (3) (2023)
Lingling Sun, Justine Mailliot, Christiane Schaffitzel
Nonsense-Mediated mRNA Decay Factor Functions in Human Health and Disease. Biomedicines 11 (3) (2023)
Ana Sofia F Oliveira, Deborah K Shoemark, Andrew D Davidson, Imre Berger, Christiane Schaffitzel, Adrian J Mulholland
SARS-CoV-2 spike variants differ in their allosteric response to linoleic acid. Journal of molecular cell biology (2023)
Christine Toelzer, Kapil Gupta, Imre Berger, Christiane Schaffitzel
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. Acta crystallographica. Section D, Structural biology 79 (Pt 2) (2023)
Joshua C Bufton, Kyle T Powers, Jenn-Yeu A Szeto, Christine Toelzer, Imre Berger, Christiane Schaffitzel
Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. Nucleic acids research 50 (10) (2022)
Johannes F Weijman, Sathish K N Yadav, Katherine J Surridge, Jessica A Cross, Ufuk Borucu, Judith M Mantell, Derek N Woolfson, Christiane Schaffitzel, Mark P Dodding
Molecular architecture of the autoinhibited kinesin-1 lambda particle. Science advances 8 (37) (2022)
Charles J Buchanan, Benjamin Gaunt, Peter J Harrison, Yun Yang, Jiwei Liu, Aziz Khan, Andrew M Giltrap, Audrey Le Bas, Philip N Ward, Kapil Gupta, Maud Dumoux, Tiong Kit Tan, Lisa Schimaski, Sergio Daga, Nicola Picchiotti, Margherita Baldassarri, Elisa Benetti, Chiara Fallerini, Francesca Fava, Annarita Giliberti, Panagiotis I Koukos, Matthew J Davy, Abirami Lakshminarayanan, Xiaochao Xue, Georgios Papadakis, Lachlan P Deimel, Virgínia Casablancas-Antràs, Timothy D W Claridge, Alexandre M J J Bonvin, Quentin J Sattentau, Simone Furini, Marco Gori, Jiandong Huo, Raymond J Owens, Christiane Schaffitzel, Imre Berger, Alessandra Renieri, null null, James H Naismith, Andrew J Baldwin, Benjamin G Davis
Pathogen-sugar interactions revealed by universal saturation transfer analysis. Science (New York, N.Y.) 377 (6604) (2022)
Justine Mailliot, Mirella Vivoli-Vega, Christiane Schaffitzel
No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors. The Biochemical journal 479 (9) (2022)
Oskar Staufer, Kapil Gupta, Jochen Estebano Hernandez Bücher, Fabian Kohler, Christian Sigl, Gunjita Singh, Kate Vasileiou, Ana Yagüe Relimpio, Meline Macher, Sebastian Fabritz, Hendrik Dietz, Elisabetta Ada Cavalcanti Adam, Christiane Schaffitzel, Alessia Ruggieri, Ilia Platzman, Imre Berger, Joachim Pius Spatz
Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein. Nature communications 13 (1) (2022)
Christine Toelzer, Kapil Gupta, Sathish K N Yadav, Lorna R Hodgson, Maia Kavanagh Williamson, Dora Buzas, Ufuk Borucu, Kyle Powers, Richard Stenner, Kate Vasileiou, Frederic Garzoni, Daniel Fitzgerald, Christine Payré, Gunjan Gautam, Gérard Lambeau, Andrew D Davidson, Paul Verkade, Martin Frank, Imre Berger, Christiane Schaffitzel
The free fatty acid-binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron. Science advances 8 (47) (2022)
Francesco Aulicino, Martin Pelosse, Christine Toelzer, Julien Capin, Erwin Ilegems, Parisa Meysami, Ruth Rollarson, Per-Olof Berggren, Mark Simon Dillingham, Christiane Schaffitzel, Moin A Saleem, Gavin I Welsh, Imre Berger
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus. Nucleic acids research 50 (13) (2022)
Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K Shoemark, Ana Sofia F Oliveira, David A Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K N Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Pius Spatz, Adrian J Mulholland, Andrew D Davidson, Christiane Schaffitzel, Imre Berger
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2. Nature communications 13 (1) (2022)
Deborah K Shoemark, Charlotte K Colenso, Christine Toelzer, Kapil Gupta, Richard B Sessions, Andrew D Davidson, Imre Berger, Christiane Schaffitzel, James Spencer, Adrian J Mulholland
Frontispiz: Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 133 (13) (2021)
Kyle T Powers, Flint Stevenson-Jones, Sathish K N Yadav, Beate Amthor, Joshua C Bufton, Ufuk Borucu, Dakang Shen, Jonas P Becker, Daria Lavysh, Matthias W Hentze, Andreas E Kulozik, Gabriele Neu-Yilik, Christiane Schaffitzel
Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic acids research 49 (13) (2021)
Deborah K Shoemark, Charlotte K Colenso, Christine Toelzer, Kapil Gupta, Richard B Sessions, Andrew D Davidson, Imre Berger, Christiane Schaffitzel, James Spencer, Adrian J Mulholland
Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein*. Angewandte Chemie (International ed. in English) 60 (13) (2021)
Christine Toelzer, Kapil Gupta, Sathish K N Yadav, Ufuk Borucu, Andrew D Davidson, Maia Kavanagh Williamson, Deborah K Shoemark, Frederic Garzoni, Oskar Staufer, Rachel Milligan, Julien Capin, Adrian J Mulholland, Joachim Spatz, Daniel Fitzgerald, Imre Berger, Christiane Schaffitzel
Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein. Science (New York, N.Y.) 370 (6517) (2020)
Imre Berger, Christiane Schaffitzel
The SARS-CoV-2 spike protein: balancing stability and infectivity. Cell research 30 (12) (2020)
Charles Vragniau, Joshua C Bufton, Frédéric Garzoni, Emilie Stermann, Fruzsina Rabi, Céline Coiffier, Véronique Josserand, Matt Williams, Christopher J Woods, Gerardo Viedma, Phil Bates, Bernard Verrier, Laurence Chaperot, Christiane Schaffitzel, Imre Berger, Pascal Fender
Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display. Science advances 5 (9) (2019)
Kapil Gupta, Christine Toelzer, Duygu Sari, Daniel J Fitzgerald, Christiane Schaffitzel, Imre Berger
MultiBac: Baculovirus-Mediated Multigene DNA Cargo Delivery in Insect and Mammalian Cells. Viruses 11 (3) (2019)
Etienne Raimondeau, Joshua C Bufton, Christiane Schaffitzel
New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors. Biochemical Society transactions 46 (3) (2018)
Imran Khan, Sudarsan Krishnaswamy, Miheer Sabale, David Groth, Linda Wijaya, Michael Morici, Imre Berger, Christiane Schaffitzel, Paul E Fraser, Ralph N Martins, Giuseppe Verdile
Efficient production of a mature and functional gamma secretase protease. Scientific reports 8 (1) (2018)
Manikandan Karuppasamy, Beata Kusmider, Taiana M Oliveira, Christl Gaubitz, Manoel Prouteau, Robbie Loewith, Christiane Schaffitzel
Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2. Nature communications 8 (1) (2017)

Christiane Schaffitzel.css-eqlu8i{font-size:small;padding-left:4px;} (C Schaffitzel)

Publication Activity (10 Years)

Top Topics

Top Venues

Christiane Schaffitzel (C Schaffitzel)