Christoph Nitsche

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 39

Top Topics

Magnetic Resonance

Top Venues

Angewandte Chemie (International ed. in English)

Chemistry (Weinheim an der Bergstrasse, Germany)

Chemical science

This page only lists publications with an associated author ORCID identifier.

Publications

Yi Jiun Tan, Elwy H Abdelkader, Eliza Tarcoveanu, Ansis Maleckis, Christoph Nitsche, Gottfried Otting
(2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19 F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect. Biochemistry (2024)
Katriona Harrison, Patrick W Carlos, Sven Ullrich, Anupriya Aggarwal, Jason Johansen-Leete, Vishnu Mini Sasi, Isabel Barter, Joshua W C Maxwell, Max J Bedding, Mark Larance, Stuart Turville, Alexander Norman, Colin J Jackson, Christoph Nitsche, Richard J Payne
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (44) (2024)
Junming He, Christoph Nitsche
Biocompatible Synthesis of Macrocyclic Thiazol(in)e Peptides. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (38) (2024)
Yi Jiun Tan, Elwy H Abdelkader, Eliza Tarcoveanu, Ansis Maleckis, Christoph Nitsche, Gottfried Otting
(2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19 F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect. Biochemistry 63 (11) (2024)
Rebecca L Frkic, Yi Jiun Tan, Elwy H Abdelkader, Ansis Maleckis, Eliza Tarcoveanu, Christoph Nitsche, Gottfried Otting, Colin J Jackson
Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein. Biochemistry (2024)
Saan Voss, Liam D Adair, Katharina Achazi, Heeyoung Kim, Silke Bergemann, Ralf F W Bartenschlager, Elizabeth J New, Jörg Rademann, Christoph Nitsche
Cell-Penetrating Peptide-Bismuth Bicycles. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Saan Voss, Liam D Adair, Katharina Achazi, Heeyoung Kim, Silke Bergemann, Ralf F W Bartenschlager, Elizabeth J New, Jörg Rademann, Christoph Nitsche
Cell-Penetrating Peptide-Bismuth Bicycles. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Saan Voss, Liam D Adair, Katharina Achazi, Heeyoung Kim, Silke Bergemann, Ralf F W Bartenschlager, Elizabeth J New, Jörg Rademann, Christoph Nitsche
Cell-Penetrating Peptide-Bismuth Bicycles. Angewandte Chemie (International ed. in English) 63 (10) (2024)
Katriona Harrison, Patrick W Carlos, Sven Ullrich, Anupriya Aggarwal, Jason Johansen-Leete, Vishnu Mini Sasi, Isabel Barter, Joshua W C Maxwell, Max J Bedding, Mark Larance, Stuart Turville, Alexander Norman, Colin J Jackson, Christoph Nitsche, Richard J Payne
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Junming He, Christoph Nitsche
Biocompatible Synthesis of Macrocyclic Thiazol(in)e Peptides. Chemistry (Weinheim an der Bergstrasse, Germany) (2024)
Junming He, Pritha Ghosh, Christoph Nitsche
Biocompatible strategies for peptide macrocyclisation. Chemical science 15 (7) (2024)
Junming He, Pritha Ghosh, Christoph Nitsche
Biocompatible strategies for peptide macrocyclisation. Chemical science 15 (7) (2024)
Rebecca L Frkic, Yi Jiun Tan, Elwy H Abdelkader, Ansis Maleckis, Eliza Tarcoveanu, Christoph Nitsche, Gottfried Otting, Colin J Jackson
Conformational Preferences of the Non-Canonical Amino Acids (2 S ,4 S )-5-Fluoroleucine, (2 S ,4 R )-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein. Biochemistry 63 (11) (2024)
Sven Ullrich, Upamali Somathilake, Ming-Hao Shang, Christoph Nitsche
Phage-encoded bismuth bicycles enable instant access to targeted bioactive peptides. Communications chemistry 7 (1) (2024)
Sven Ullrich, Upamali Somathilake, Ming-Hao Shang, Christoph Nitsche
Phage-encoded bismuth bicycles enable instant access to targeted bioactive peptides. Communications chemistry 7 (1) (2024)
Junming He, Christoph Nitsche
Biocompatible Synthesis of Macrocyclic Thiazol(in)e Peptides. Chemistry (Weinheim an der Bergstrasse, Germany) 30 (38) (2024)
Sven Ullrich, Upamali Somathilake, Ming-Hao Shang, Christoph Nitsche
Phage-encoded bismuth bicycles enable instant access to targeted bioactive peptides. Communications chemistry 7 (1) (2024)
Saan Voss, Liam D Adair, Katharina Achazi, Heeyoung Kim, Silke Bergemann, Ralf F W Bartenschlager, Elizabeth J New, Jörg Rademann, Christoph Nitsche
Cell-Penetrating Peptide-Bismuth Bicycles. Angewandte Chemie (International ed. in English) (2023)
Minglong Liu, Richard Morewood, Ryoji Yoshisada, Mirte N Pascha, Antonius J P Hopstaken, Eliza Tarcoveanu, David A Poole, Cornelis A M de Haan, Christoph Nitsche, Seino A K Jongkees
Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis. Chemical science 14 (38) (2023)
Alexandra E Coram, Richard Morewood, Saan Voss, Joshua L Price, Christoph Nitsche
Exploring biocompatible chemistry to create stapled and photoswitchable variants of the antimicrobial peptide aurein 1.2. Journal of peptide science : an official publication of the European Peptide Society (2023)
Kasuni B Ekanayake, Mithun C Mahawaththa, Haocheng Qianzhu, Elwy H Abdelkader, Josemon George, Sven Ullrich, Rhys B Murphy, Sarah E Fry, Jason Johansen-Leete, Richard J Payne, Christoph Nitsche, Thomas Huber, Gottfried Otting
Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids. Journal of medicinal chemistry (2023)
Lani J Davies, Laura M Shuttleworth, Xiaobai Zhang, Sherry Peng, Christoph Nitsche
Bioorthogonal Peptide Macrocyclization Using Oxime Ligation. Organic letters (2023)
Yuwen Jia, Barbara Schroeder, Yvonne Pfeifer, Christopher Fröhlich, Lihua Deng, Christoph Arkona, Benno Kuropka, Jana Sticht, Kenichi Ataka, Silke Bergemann, Gerhard Wolber, Christoph Nitsche, Martin Mielke, Hanna-Kirsti S Leiros, Guido Werner, Jörg Rademann
Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase-1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems. Journal of medicinal chemistry (2023)
Sven Ullrich, Christoph Nitsche
SARS-CoV-2 Papain-Like Protease: Structure, Function and Inhibition. Chembiochem : a European journal of chemical biology 23 (19) (2022)
Sven Ullrich, Josemon George, Alexandra E Coram, Richard Morewood, Christoph Nitsche
Biocompatible and Selective Generation of Bicyclic Peptides. Angewandte Chemie (International ed. in English) 61 (43) (2022)
Vishnu M Sasi, Sven Ullrich, Jennifer Ton, Sarah E Fry, Jason Johansen-Leete, Richard J Payne, Christoph Nitsche, Colin J Jackson
Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening. Biochemistry 61 (22) (2022)
Qing Miao, Christoph Nitsche, Henry Orton, Mark Overhand, Gottfried Otting, Marcellus Ubbink
Paramagnetic Chemical Probes for Studying Biological Macromolecules. Chemical reviews 122 (10) (2022)
Elwy H Abdelkader, Haocheng Qianzhu, Josemon George, Rebecca L Frkic, Colin J Jackson, Christoph Nitsche, Gottfried Otting, Thomas Huber
Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction. Angewandte Chemie (International ed. in English) 61 (13) (2022)
Richard Morewood, Christoph Nitsche
Bioinspired peptide stapling generates stable enzyme inhibitors. Chemical communications (Cambridge, England) 58 (77) (2022)
Jason Johansen-Leete, Sven Ullrich, Sarah E Fry, Rebecca Frkic, Max J Bedding, Anupriya Aggarwal, Anneliese S Ashhurst, Kasuni B Ekanayake, Mithun C Mahawaththa, Vishnu M Sasi, Stephanie Luedtke, Daniel J Ford, Anthony J O'Donoghue, Toby Passioura, Mark Larance, Gottfried Otting, Stuart Turville, Colin J Jackson, Christoph Nitsche, Richard J Payne
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2. Chemical science 13 (13) (2022)
Mithun C Mahawaththa, Henry W Orton, Ibidolapo Adekoya, Thomas Huber, Gottfried Otting, Christoph Nitsche
Organoarsenic probes to study proteins by NMR spectroscopy. Chemical communications (Cambridge, England) 58 (5) (2022)
Nitin A Patil, Jun-Ping Quek, Barbara Schroeder, Richard Morewood, Jörg Rademann, Dahai Luo, Christoph Nitsche
2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease. ACS medicinal chemistry letters 12 (5) (2021)
Barbara Schroeder, Peter Demirel, Christina Fischer, Enaam Masri, Stephanie Kallis, Lisa Redl, Thomas Rudolf, Silke Bergemann, Christoph Arkona, Christoph Nitsche, Ralf Bartenschlager, Jörg Rademann
Nanoparticular Inhibitors of Flavivirus Proteases from Zika, West Nile and Dengue Virus Are Cell-Permeable Antivirals. ACS medicinal chemistry letters 12 (12) (2021)
Saan Voss, Christoph Nitsche
Targeting the protease of West Nile virus. RSC medicinal chemistry 12 (8) (2021)
Saan Voss, Jörg Rademann, Christoph Nitsche
Peptide-Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity. Angewandte Chemie (International ed. in English) (2021)
Richard Morewood, Christoph Nitsche
A biocompatible stapling reaction for in situ generation of constrained peptides. Chemical science 12 (2) (2020)
Christoph Nitsche, Hideki Onagi, Jun-Ping Quek, Gottfried Otting, Dahai Luo, Thomas Huber
Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors. Organic letters 21 (12) (2019)
Christoph Nitsche
Proteases from dengue, West Nile and Zika viruses as drug targets. Biophysical reviews 11 (2) (2019)
Walter Becker, Luke A Adams, Bim Graham, Gabriel E Wagner, Klaus Zangger, Gottfried Otting, Christoph Nitsche
Trimethylsilyl tag for probing protein-ligand interactions by NMR. Journal of biomolecular NMR 70 (4) (2018)