Anthony J O'Donoghue (Anthony O'Donoghue)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Venues

ACS omega

bioRxiv : the preprint server for biology

ACS chemical biology

Chemical science

UC San Diego

This page only lists publications with an associated author ORCID identifier.

Affiliation History

UC San Diego Jul 01 2015

United States

Assistant Professor :: Skaggs School of Pharmacy and Pharmaceutical Sciences

Publications

Zhenze Jiang, Elany Barbosa da Silva, Chenxi Liu, Pavla Fajtova, Lawrence J Liu, Nelly El-Sakkary, Danielle E Skinner, Ali Syed, Steven C Wang, Conor R Caffrey, Anthony J O'Donoghue
Development of subunit selective proteasome substrates for Schistosoma species . bioRxiv : the preprint server for biology (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Zhenze Jiang, Elany Barbosa da Silva, Chenxi Liu, Pavla Fajtova, Lawrence J Liu, Nelly El-Sakkary, Danielle E Skinner, Ali Syed, Steven C Wang, Conor R Caffrey, Anthony J O'Donoghue
Development of subunit selective proteasome substrates for Schistosoma species . bioRxiv : the preprint server for biology (2024)
Lawrence J Liu, Bobby Lucero, Cindy Manriquez-Rodriguez, Karol R Francisco, Thaiz R Teixeira, Darius J Yohannan, Carlo Ballatore, Samuel A Myers, Anthony J O'Donoghue, Conor R Caffrey
Clickable Probes for Pathogen Proteasomes: Synthesis and Applications. ACS omega 9 (32) (2024)
Lawrence J Liu, Bobby Lucero, Cindy Manriquez-Rodriguez, Karol R Francisco, Thaiz R Teixeira, Darius J Yohannan, Carlo Ballatore, Samuel A Myers, Anthony J O'Donoghue, Conor R Caffrey
Clickable Probes for Pathogen Proteasomes: Synthesis and Applications. ACS omega 9 (32) (2024)
Jehad Almaliti, Momen Alhindy, Michael C Yoon, Vivian Hook, Tadeusz F Molinski, Anthony J O'Donoghue, William H Gerwick
Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS omega 9 (3) (2024)
Zhenze Jiang, Elany Barbosa da Silva, Chenxi Liu, Pavla Fajtova, Lawrence J Liu, Nelly El-Sakkary, Danielle E Skinner, Ali Syed, Steven C Wang, Conor R Caffrey, Anthony J O'Donoghue
Development of subunit selective proteasome substrates for Schistosoma species . bioRxiv : the preprint server for biology (2024)
Lawrence J Liu, Bobby Lucero, Cindy Manriquez-Rodriguez, Karol R Francisco, Thaiz R Teixeira, Darius J Yohannan, Carlo Ballatore, Samuel A Myers, Anthony J O'Donoghue, Conor R Caffrey
Clickable Probes for Pathogen Proteasomes: Synthesis and Applications. ACS omega 9 (32) (2024)
Jehad Almaliti, Pavla Fajtova, Jaeson Santos Calla-Choque, Gregory M LaMonte, Mudong Feng, Frances Rocamora, Sabine Ottilie, Evgenia Glukhov, Evzen Boura, Raymond T Suhandynata, Jeremiah D Momper, Michael K Gilson, Elizabeth A Winzeler, William H Gerwick, Anthony J O'Donoghue
Development of Potent and Highly Selective Epoxyketone-Based Plasmodium Proteasome Inhibitors. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Pavla Fajtova, Brianna M Hurysz, Yukiko Miyamoto, Mateus Sá Magalhães Serafim, Zhenze Jiang, Diego F Trujillo, Lawrence Liu, Urvashi Somani, Jehad Almaliti, Samuel A Myers, Conor R Caffrey, William H Gerwick, Christopher J Kirk, Evzen Boura, Lars Eckmann, Anthony J O'Donoghue
Development of subunit selective substrates for Trichomonas vaginalis proteasome. bioRxiv : the preprint server for biology (2023)
Victoria Røyseth, Brianna M Hurysz, Anna Kaczorowska, Sebastian Dorawa, Anita-Elin Fedøy, Hasan Arsin, Mateus Serafim, Olesia Werbowy, Tadeusz Kaczorowski, Runar Stokke, Anthony J O'Donoghue, Ida Helene Steen
Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system. bioRxiv : the preprint server for biology (2023)
Yu-Ci Chang, Zhicheng Jin, Ke Li, Jiajing Zhou, Wonjun Yim, Justin Yeung, Yong Cheng, Maurice Retout, Matthew N Creyer, Pavla Fajtova, Tengyu He, Xi Chen, Anthony J O'Donoghue, Jesse V Jokerst
Peptide valence-induced breaks in plasmonic coupling. Chemical science 14 (10) (2023)
Yu-Ci Chang, Zhicheng Jin, Ke Li, Jiajing Zhou, Wonjun Yim, Justin Yeung, Yong Cheng, Maurice Retout, Matthew N Creyer, Pavla Fajtova, Tengyu He, Xi Chen, Anthony J O'Donoghue, Jesse V Jokerst
Peptide valence-induced breaks in plasmonic coupling. Chemical science 14 (10) (2023)
Joleen P Z Goh, Fiorella Ruchti, Si En Poh, Winston L C Koh, Kiat-Yi Tan, Yan Ting Lim, Steven T G Thng, Radoslaw Mikolaj Sobota, Shawn S Hoon, Chenxi Liu, Anthony J O'Donoghue, Salomé LeibundGut-Landmann, Hazel Hweeboon Oon, Hao Li, Thomas L Dawson
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (49) (2022)
Michael C Yoon, Mitchell P Christy, Von V Phan, William H Gerwick, Gregory Hook, Anthony J O'Donoghue, Vivian Hook
Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B. Biochemistry 61 (4) (2022)
Zhicheng Jin, Yash Mantri, Maurice Retout, Yong Cheng, Jiajing Zhou, Alec Jorns, Pavla Fajtova, Wonjun Yim, Colman A Moore, Ming Xu, Matthew N Creyer, Raina M Borum, Jingcheng Zhou, Zhuohong Wu, Tengyu He, William F Penny, Anthony J O'Donoghue, Jesse V Jokerst
A Charge-Switchable Zwitterionic Peptide for Rapid Detection of SARS-CoV-2 Main Protease. Angewandte Chemie (International ed. in English) 61 (9) (2022)
Elany Barbosa da Silva, Vandna Sharma, Lilian Hernandez-Alvarez, Arthur H Tang, Alexander Stoye, Anthony J O'Donoghue, William H Gerwick, Richard J Payne, James H McKerrow, Larissa M Podust
Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi . Journal of medicinal chemistry 65 (5) (2022)
Lucianna H Santos, Thales Kronenberger, Renata G Almeida, Elany Barbosa da Silva, Rafael E O Rocha, Joyce C Oliveira, Luiza V Barreto, Danielle Skinner, Pavla Fajtová, Miriam A Giardini, Brendon Woodworth, Conner Bardine, André L Lourenço, Charles S Craik, Antti Poso, Larissa M Podust, James H McKerrow, Jair Lage Siqueira-Neto, Anthony J O'Donoghue, Eufrânio N da Silva Júnior, Rafaela Salgado Ferreira
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M pro and Papain-like Protease PL pro of SARS-CoV-2. Journal of chemical information and modeling (2022)
Ming Xu, Jiajing Zhou, Yong Cheng, Zhicheng Jin, Alex E Clark, Tengyu He, Wonjun Yim, Yi Li, Yu-Ci Chang, Zhuohong Wu, Pavla Fajtová, Anthony J O'Donoghue, Aaron F Carlin, Michael D Todd, Jesse V Jokerst
A Self-Immolative Fluorescent Probe for Selective Detection of SARS-CoV-2 Main Protease. Analytical chemistry 94 (34) (2022)
Jason Johansen-Leete, Sven Ullrich, Sarah E Fry, Rebecca Frkic, Max J Bedding, Anupriya Aggarwal, Anneliese S Ashhurst, Kasuni B Ekanayake, Mithun C Mahawaththa, Vishnu M Sasi, Stephanie Luedtke, Daniel J Ford, Anthony J O'Donoghue, Toby Passioura, Mark Larance, Gottfried Otting, Stuart Turville, Colin J Jackson, Christoph Nitsche, Richard J Payne
Antiviral cyclic peptides targeting the main protease of SARS-CoV-2. Chemical science 13 (13) (2022)
Sonia Podvin, Zhenze Jiang, Ben Boyarko, Leigh-Ana Rossitto, Anthony J O'Donoghue, Robert A Rissman, Vivian Hook
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer's Disease Brain. ACS chemical neuroscience 13 (13) (2022)
Kathleen Luskin, Diba Mortazavi, Sherry Bai-Tong, Kerri Bertrand, Christina Chambers, Keriann Schulkers-Escalante, Alla Ahmad, Stephanie Luedtke, Anthony J O'Donoghue, Majid Ghassemian, Bob Geng, Sandra L Leibel, Sydney A Leibel
Allergen Content and Protease Activity in Milk Feeds from Mothers of Preterm Infants. Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine 17 (11) (2022)
Von V Phan, Charles Mosier, Michael C Yoon, Evgenia Glukhov, Conor R Caffrey, Anthony J O'Donoghue, William H Gerwick, Vivian Hook
Discovery of pH-Selective Marine and Plant Natural Product Inhibitors of Cathepsin B Revealed by Screening at Acidic and Neutral pH Conditions. ACS omega 7 (29) (2022)
Ittipat Meewan, Jacob Kattoula, Julius Y Kattoula, Danielle Skinner, Pavla Fajtová, Miriam A Giardini, Brendon Woodworth, James H McKerrow, Jair Lage Siqueira-Neto, Anthony J O'Donoghue, Ruben Abagyan
Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L. Pharmaceuticals (Basel, Switzerland) 15 (6) (2022)
Drake M Mellott, Chien-Te Tseng, Aleksandra Drelich, Pavla Fajtová, Bala C Chenna, Demetrios H Kostomiris, Jason Hsu, Jiyun Zhu, Zane W Taylor, Klaudia I Kocurek, Vivian Tat, Ardala Katzfuss, Linfeng Li, Miriam A Giardini, Danielle Skinner, Ken Hirata, Michael C Yoon, Sungjun Beck, Aaron F Carlin, Alex E Clark, Laura Beretta, Daniel Maneval, Vivian Hook, Felix Frueh, Brett L Hurst, Hong Wang, Frank M Raushel, Anthony J O'Donoghue, Jair Lage de Siqueira-Neto, Thomas D Meek, James H McKerrow
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells. ACS chemical biology 16 (4) (2021)
Colman A Moore, Raina M Borum, Yash Mantri, Ming Xu, Pavla Fajtová, Anthony J O'Donoghue, Jesse V Jokerst
Activatable Carbocyanine Dimers for Photoacoustic and Fluorescent Detection of Protease Activity. ACS sensors 6 (6) (2021)
Zhenze Jiang, Christopher B Lietz, Sonia Podvin, Michael C Yoon, Thomas Toneff, Vivian Hook, Anthony J O'Donoghue
Differential Neuropeptidomes of Dense Core Secretory Vesicles (DCSV) Produced at Intravesicular and Extracellular pH Conditions by Proteolytic Processing. ACS chemical neuroscience 12 (13) (2021)
Matthew Mahoney, Vishnu C Damalanka, Michael A Tartell, Dong Hee Chung, André Luiz Lourenço, Dustin Pwee, Anne E Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P Azouz, Andrea M Klingler, Paul W Rothlauf, Cassandra E Thompson, Melody Lee, Lidija Klampfer, Christina L Stallings, Marc E Rothenberg, Stefan H Pöhlmann, Sean P J Whelan, Anthony J O'Donoghue, Charles S Craik, James W Janetka
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America 118 (43) (2021)
George R Wendt, Lu Zhao, Rui Chen, Chenxi Liu, Anthony J O'Donoghue, Conor R Caffrey, Michael L Reese, James J Collins
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. Science (New York, N.Y.) 369 (6511) (2020)
Lena Keller, Kirley Marques Canuto, Chenxi Liu, Brian M Suzuki, Jehad Almaliti, Asfandyar Sikandar, C Benjamin Naman, Evgenia Glukhov, Danmeng Luo, Brendan M Duggan, Hendrik Luesch, Jesko Koehnke, Anthony J O'Donoghue, William H Gerwick
Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. ACS chemical biology 15 (3) (2020)
Elisa Maffioli, Zhenze Jiang, Simona Nonnis, Armando Negri, Valentina Romeo, Christopher B Lietz, Vivian Hook, Giuseppe Ristagno, Giuseppe Baselli, Erik B Kistler, Federico Aletti, Anthony J O'Donoghue, Gabriella Tedeschi
High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma. Molecules (Basel, Switzerland) 25 (18) (2020)
Betsaida Bibo-Verdugo, Steven C Wang, Jehad Almaliti, Anh P Ta, Zhenze Jiang, Derek A Wong, Christopher B Lietz, Brian M Suzuki, Nelly El-Sakkary, Vivian Hook, Guy S Salvesen, William H Gerwick, Conor R Caffrey, Anthony J O'Donoghue
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni. ACS infectious diseases 5 (10) (2019)
Vishnu C Damalanka, Zhenfu Han, Partha Karmakar, Anthony J O'Donoghue, Florencia La Greca, Tommy Kim, Shishir M Pant, Jonathan Helander, Juha Klefström, Charles S Craik, James W Janetka
Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. Journal of medicinal chemistry 62 (2) (2019)
Anthony J O'Donoghue, Betsaida Bibo-Verdugo, Yukiko Miyamoto, Steven C Wang, Justin Z Yang, Douglas E Zuill, Shoun Matsuka, Zhenze Jiang, Jehad Almaliti, Conor R Caffrey, William H Gerwick, Lars Eckmann
20S Proteasome as a Drug Target in Trichomonas vaginalis. Antimicrobial agents and chemotherapy 63 (11) (2019)
Janice H Xu, Zhenze Jiang, Angelo Solania, Sandip Chatterjee, Brian Suzuki, Christopher B Lietz, Vivian Y H Hook, Anthony J O'Donoghue, Dennis W Wolan
A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. ACS chemical biology 13 (9) (2018)
Michael B Winter, Florencia La Greca, Shirin Arastu-Kapur, Francesco Caiazza, Peter Cimermancic, Tonia J Buchholz, Janet L Anderl, Matthew Ravalin, Markus F Bohn, Andrej Sali, Anthony J O'Donoghue, Charles S Craik
Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6 (2017)

Anthony J O'Donoghue.css-eqlu8i{font-size:small;padding-left:4px;} (Anthony O'Donoghue)

Publication Activity (10 Years)

Top Topics

Top Venues

Anthony J O'Donoghue (Anthony O'Donoghue)