Christopher A Vakulskas

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Venues

Nature communications

Blood advances

Nature medicine

Nature biotechnology

Integrated DNA Technologies Inc

University of Iowa (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Integrated DNA Technologies Inc Jul 15 2015

United States

Senior Staff Scientist :: Molecular Genetics

University of Florida Feb 10 2010 - Jul 12 2015

United States

NIH Postdoctoral Fellow :: Microbiology and Cell Science

Education History

University of Iowa Aug 10 2005 - Jan 05 2010

United States

PHD :: College of Medicine

University of Iowa Aug 10 2002 - May 16 2005

United States

BSC :: College of Liberal Arts and Sciences

Publications

Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Matthew H Porteus, Cameron L Gardner, Yusuke Nakauchi, Tomoki Kawai, Ottavia Maria Delmonte, Boaz Palterer, Marita Bosticardo, Francesca Pala, Sebastien Viel, Harry L Malech, Hana Y Ghanim, Nicole M Bode, Gavin L Kurgan, Angela M Detweiler, Christopher A Vakulskas, Norma F Neff, Adam Sheikali, Sherah T Menezes, Jade Chrobok, Elaine M Hernández González, Ravindra Majeti, Luigi Daniele Notarangelo, Matthew H Porteus
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency. Blood advances 8 (7) (2024)
Matthew H Porteus, Cameron L Gardner, Yusuke Nakauchi, Tomoki Kawai, Ottavia Maria Delmonte, Boaz Palterer, Marita Bosticardo, Francesca Pala, Sebastien Viel, Harry L Malech, Hana Y Ghanim, Nicole M Bode, Gavin L Kurgan, Angela M Detweiler, Christopher A Vakulskas, Norma F Neff, Adam Sheikali, Sherah T Menezes, Jade Chrobok, Elaine M Hernández González, Ravindra Majeti, Luigi Daniele Notarangelo, Matthew H Porteus
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency. Blood advances 8 (7) (2024)
Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Matthew H Porteus, Cameron L Gardner, Yusuke Nakauchi, Tomoki Kawai, Ottavia Maria Delmonte, Boaz Palterer, Marita Bosticardo, Francesca Pala, Sebastien Viel, Harry L Malech, Hana Y Ghanim, Nicole M Bode, Gavin L Kurgan, Angela M Detweiler, Christopher A Vakulskas, Norma F Neff, Adam Sheikali, Sherah T Menezes, Jade Chrobok, Elaine M Hernández González, Ravindra Majeti, Luigi Daniele Notarangelo, Matthew H Porteus
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency. Blood advances 8 (7) (2024)
Matthew H Porteus, Cameron L Gardner, Yusuke Nakauchi, Tomoki Kawai, Ottavia Maria Delmonte, Boaz Palterer, Marita Bosticardo, Francesca Pala, Sebastien Viel, Harry L Malech, Hana Y Ghanim, Nicole M Bode, Gavin L Kurgan, Angela M Detweiler, Christopher A Vakulskas, Norma F Neff, Adam Sheikali, Sherah T Menezes, Jade Chrobok, Elaine M Hernández González, Ravindra Majeti, Luigi Daniele Notarangelo, Matthew H Porteus
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency. Blood advances 8 (7) (2024)
Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Jacob E Corn, M Kyle Cromer, Steve E Glenn, Christopher A Vakulskas, Kay O Chmielewski, Amanda M Dudek, William N Feist, Julia Klermund, Suzette Shipp, Toni Cathomen, Daniel P Dever, Matthew H Porteus
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells. Nature communications 15 (1) (2024)
Hang Su, Yuanchun Wang, Jin Xu, Ahmad Alsayed Omar, Jude W Grosser, Milica Calovic, Liyang Zhang, Yu Feng, Christopher A Vakulskas, Nian Wang
Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation. Nature communications 14 (1) (2023)
Mara Pavel-Dinu, Cameron L Gardner, Yusuke Nakauchi, Tomoki Kawai, Ottavia Maria Delmonte, Boaz Palterer, Marita Bosticardo, Francesca Pala, Sebastien Viel, Harry L Malech, Hana Y Ghanim, Nicole M Bode, Gavin L Kurgan, Angela M Detweiler, Christopher A Vakulskas, Norma F Neff, Adam Sheikali, Sherah T Menezes, Jade Chrobok, Elaine M Hernández González, Ravindra Majeti, Luigi Daniele Notarangelo, Matthew H Porteus
Genetically Corrected RAG2-SCID Human Hematopoietic Stem Cells Restore V(D)J-Recombinase and Rescue Lymphoid Deficiency. Blood advances (2023)
Matthew T N Yarnall, Eleonora I Ioannidi, Cian Schmitt-Ulms, Rohan N Krajeski, Justin Lim, Lukas Villiger, Wenyuan Zhou, Kaiyi Jiang, Sofya K Garushyants, Nathaniel Roberts, Liyang Zhang, Christopher A Vakulskas, John A Walker, Anastasia P Kadina, Adrianna E Zepeda, Kevin Holden, Hong Ma, Jun Xie, Guangping Gao, Lander Foquet, Greg Bial, Sara K Donnelly, Yoshinari Miyata, Daniel R Radiloff, Jordana M Henderson, Andrew Ujita, Omar O Abudayyeh, Jonathan Samuel Gootenberg
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases. Nature biotechnology (2022)
Liyang Zhang, John A Zuris, Ramya Viswanathan, Jasmine N Edelstein, Rolf Turk, Bernice Thommandru, H Tomas Rube, Steve E Glenn, Michael A Collingwood, Nicole M Bode, Sarah F Beaudoin, Swarali Lele, Sean N Scott, Kevin M Wasko, Steven Sexton, Christopher M Borges, Mollie S Schubert, Gavin L Kurgan, Matthew S McNeill, Cecilia A Fernandez, Vic E Myer, Richard A Morgan, Mark A Behlke, Christopher A Vakulskas
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines. Nature communications 12 (1) (2021)
M Kyle Cromer, Joab Camarena, Renata M Martin, Benjamin J Lesch, Christopher A Vakulskas, Nicole M Bode, Gavin L Kurgan, Michael A Collingwood, Garrett R Rettig, Mark A Behlke, Viktor T Lemgart, Yankai Zhang, Ankush Goyal, Feifei Zhao, Ezequiel Ponce, Waracharee Srifa, Rasmus O Bak, Naoya Uchida, Ravindra Majeti, Vivien A Sheehan, John F Tisdale, Daniel P Dever, Matthew H Porteus
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells. Nature medicine 27 (4) (2021)
Liyang Zhang, John A Zuris, Ramya Viswanathan, Jasmine N Edelstein, Rolf Turk, Bernice Thommandru, H Tomas Rube, Steve E Glenn, Michael A Collingwood, Nicole M Bode, Sarah F Beaudoin, Swarali Lele, Sean N Scott, Kevin M Wasko, Steven Sexton, Christopher M Borges, Mollie S Schubert, Gavin L Kurgan, Matthew S McNeill, Cecilia A Fernandez, Vic E Myer, Richard A Morgan, Mark A Behlke, Christopher A Vakulskas
Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines. Nature communications 12 (1) (2021)
Carsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, Joab Camarena, Viktor T Lemgart, M Kyle Cromer, Christopher A Vakulskas, Michael A Collingwood, Liyang Zhang, Nicole M Bode, Mark A Behlke, Beruh Dejene, Brandon Cieniewicz, Rosa Romano, Benjamin J Lesch, Natalia Gomez-Ospina, Sruthi Mantri, Mara Pavel-Dinu, Kenneth I Weinberg, Matthew H Porteus
Identification of preexisting adaptive immunity to Cas9 proteins in humans. Nature medicine 25 (2) (2019)
Christopher A Vakulskas, Daniel P Dever, Garrett R Rettig, Rolf Turk, Ashley M Jacobi, Michael A Collingwood, Nicole M Bode, Matthew S McNeill, Shuqi Yan, Joab Camarena, Ciaran M Lee, So Hyun Park, Volker Wiebking, Rasmus O Bak, Natalia Gomez-Ospina, Mara Pavel-Dinu, Wenchao Sun, Gang Bao, Matthew H Porteus, Mark A Behlke
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells. Nature medicine 24 (8) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Christopher A Vakulskas