Ciaran M Lee (Ciaran Lee, E Lee)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 27

Top Venues

Gut microbes

Microbial biotechnology

Nature communications

Science translational medicine

University College Cork APC Microbiome Institute

University College Cork (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University College Cork APC Microbiome Institute

Ireland

Senior Postdoctoral Fellow

Rice University Jul 01 2015

United States

Director Genome Editing Core :: Bioengineering

Georgia Institute of Technology Jul 01 2013 - Jun 30 2015

United States

Postdoctoral Scholar :: Biomedical Engineering

University College Cork Oct 01 2010 - Sep 30 2012

Ireland

Postdoctoral Fellow :: Physiology

Education History

University College Cork Oct 01 2006 - Dec 30 2011

Ireland

PHD :: Physiology

University College Cork Sep 01 2002 - Jun 01 2006

Ireland

BSC :: Biochemistry

Publications

Sonia Mirjam Rizzo, Laura Maria Vergna, Giulia Alessandri, Ciaran M Lee, Federico Fontana, Gabriele Andrea Lugli, Luca Carnevali, Massimiliano G Bianchi, Margherita Barbetti, Giuseppe Taurino, Andrea Sgoifo, Ovidio Bussolati, Francesca Turroni, Douwe Van Sinderen, Marco Ventura
GH136-encoding gene (perB) is involved in gut colonization and persistence by Bifidobacterium bifidum PRL2010. Microbial biotechnology (2024)
Lisa Friess, Francesca Bottacini, Fionnuala M Mcauliffe, Ian J O'Neill, Paul D Cotter, Ciaran M Lee, Jose Munoz-Munoz, Douwe van Sinderen
Two extracellular α-arabinofuranosidases are required for cereal-derived arabinoxylan metabolism by Bifidobacterium longum subsp. longum . Gut microbes 16 (1) (2024)
Rocio Sanchez-Gallardo, Paula M O'Connor, Ian J O'Neill, Brian McDonnell, Ciaran M Lee, Rebecca L Moore, Fionnuala M Mcauliffe, Paul D Cotter, Douwe van Sinderen
Pseudocin 196, a novel lantibiotic produced by Bifidobacterium pseudocatenulatum elicits antimicrobial activity against clinically relevant pathogens. Gut microbes 16 (1) (2024)
Sonia Mirjam Rizzo, Laura Maria Vergna, Giulia Alessandri, Ciaran M Lee, Federico Fontana, Gabriele Andrea Lugli, Luca Carnevali, Massimiliano G Bianchi, Margherita Barbetti, Giuseppe Taurino, Andrea Sgoifo, Ovidio Bussolati, Francesca Turroni, Douwe Van Sinderen, Marco Ventura
GH136-encoding gene (perB) is involved in gut colonization and persistence by Bifidobacterium bifidum PRL2010. Microbial biotechnology 17 (2) (2024)
Sonia Mirjam Rizzo, Laura Maria Vergna, Giulia Alessandri, Ciaran M Lee, Federico Fontana, Gabriele Andrea Lugli, Luca Carnevali, Massimiliano G Bianchi, Margherita Barbetti, Giuseppe Taurino, Andrea Sgoifo, Ovidio Bussolati, Francesca Turroni, Douwe Van Sinderen, Marco Ventura
GH136-encoding gene (perB) is involved in gut colonization and persistence by Bifidobacterium bifidum PRL2010. Microbial biotechnology 17 (2) (2024)
Lisa Friess, Francesca Bottacini, Fionnuala M Mcauliffe, Ian J O'Neill, Paul D Cotter, Ciaran M Lee, Jose Munoz-Munoz, Douwe van Sinderen
Two extracellular α-arabinofuranosidases are required for cereal-derived arabinoxylan metabolism by Bifidobacterium longum subsp. longum . Gut microbes 16 (1) (2024)
Rocio Sanchez-Gallardo, Paula M O'Connor, Ian J O'Neill, Brian McDonnell, Ciaran M Lee, Rebecca L Moore, Fionnuala M Mcauliffe, Paul D Cotter, Douwe van Sinderen
Pseudocin 196, a novel lantibiotic produced by Bifidobacterium pseudocatenulatum elicits antimicrobial activity against clinically relevant pathogens. Gut microbes 16 (1) (2024)
Rocio Sanchez-Gallardo, Paula M O'Connor, Ian J O'Neill, Brian McDonnell, Ciaran M Lee, Rebecca L Moore, Fionnuala M Mcauliffe, Paul D Cotter, Douwe van Sinderen
Pseudocin 196, a novel lantibiotic produced by Bifidobacterium pseudocatenulatum elicits antimicrobial activity against clinically relevant pathogens. Gut microbes 16 (1) (2024)
Sonia Mirjam Rizzo, Laura Maria Vergna, Giulia Alessandri, Ciaran M Lee, Federico Fontana, Gabriele Andrea Lugli, Luca Carnevali, Massimiliano G Bianchi, Margherita Barbetti, Giuseppe Taurino, Andrea Sgoifo, Ovidio Bussolati, Francesca Turroni, Douwe Van Sinderen, Marco Ventura
GH136-encoding gene (perB) is involved in gut colonization and persistence by Bifidobacterium bifidum PRL2010. Microbial biotechnology 17 (2) (2024)
Lisa Friess, Francesca Bottacini, Fionnuala M Mcauliffe, Ian J O'Neill, Paul D Cotter, Ciaran M Lee, Jose Munoz-Munoz, Douwe van Sinderen
Two extracellular α-arabinofuranosidases are required for cereal-derived arabinoxylan metabolism by Bifidobacterium longum subsp. longum . Gut microbes 16 (1) (2024)
Lisa Friess, Francesca Bottacini, Fionnuala M Mcauliffe, Ian J O'Neill, Paul D Cotter, Ciaran M Lee, Jose Munoz-Munoz, Douwe van Sinderen
Two extracellular α-arabinofuranosidases are required for cereal-derived arabinoxylan metabolism by Bifidobacterium longum subsp. longum . Gut microbes 16 (1) (2024)
Sonia Mirjam Rizzo, Laura Maria Vergna, Giulia Alessandri, Ciaran M Lee, Federico Fontana, Gabriele Andrea Lugli, Luca Carnevali, Massimiliano G Bianchi, Margherita Barbetti, Giuseppe Taurino, Andrea Sgoifo, Ovidio Bussolati, Francesca Turroni, Douwe Van Sinderen, Marco Ventura
GH136-encoding gene (perB) is involved in gut colonization and persistence by Bifidobacterium bifidum PRL2010. Microbial biotechnology 17 (2) (2024)
Rocio Sanchez-Gallardo, Paula M O'Connor, Ian J O'Neill, Brian McDonnell, Ciaran M Lee, Rebecca L Moore, Fionnuala M Mcauliffe, Paul D Cotter, Douwe van Sinderen
Pseudocin 196, a novel lantibiotic produced by Bifidobacterium pseudocatenulatum elicits antimicrobial activity against clinically relevant pathogens. Gut microbes 16 (1) (2024)
Annalisa Lattanzi, Joab Camarena, Premanjali Lahiri, Helen Segal, Waracharee Srifa, Christopher A Vakulskas, Richard L Frock, Josefin Kenrick, Ciaran M Lee, Narae Talbott, Jason Skowronski, M Kyle Cromer, Carsten T Charlesworth, Rasmus O Bak, Sruthi Mantri, Gang Bao, David DiGiusto, John F Tisdale, J Fraser Wright, Neehar Bhatia, Maria Grazia Roncarolo, Daniel P Dever, Matthew H Porteus
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease. Science translational medicine 13 (598) (2021)
Jerzy A Woznicki, Nisha Saini, Peter Flood, Subhasree Rajaram, Ciaran M Lee, Panagiota Stamou, Agnieszka Skowyra, Milan Bustamante-Garrido, Karine Regazzoni, Nyree Crawford, Simon S McDade, Daniel B Longley, Pedro Aza-Blanc, Fergus Shanahan, Syed A Zulquernain, Jane McCarthy, Silvia Melgar, Bradford L McRae, Ken Nally
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells. Cell death & disease 12 (10) (2021)
Nicole N Thadani, Joanna Yang, Buhle Moyo, Ciaran M Lee, Maria Y Chen, Gang Bao, Junghae Suh
Site-Specific Post-translational Surface Modification of Adeno-Associated Virus Vectors Using Leucine Zippers. ACS synthetic biology 9 (3) (2020)
M Goodwin, Ciaran M Lee, U Lakshmanan, S Shipp, Luise J Froessl, F Barzaghi, L Passerini, M Narula, A Sheikali, C M Lee, G Bao, C S Bauer, H K Miller, M Garcia-Lloret, Manish J Butte, Alice Bertaina, Ami J Shah, Matthew H Porteus, A Hendel, Matthew H Porteus, M G Roncarolo, Rosa Bacchetta
CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells. Science advances 6 (19) (2020)
Olivier Humbert, Stefan Radtke, Clare Samuelson, Ray R Carrillo, Anai M Perez, Sowmya S Reddy, Christopher Lux, Sowmya Pattabhi, Lauren E Schefter, Olivier Negre, Ciaran M Lee, Gang Bao, Jennifer E Adair, Christopher W Peterson, David J Rawlings, Andrew M Scharenberg, Hans-Peter Kiem
Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates. Science translational medicine 11 (503) (2020)
Volker Wiebking, James O Patterson, Renata M Martin, Monica K Chanda, Ciaran M Lee, Waracharee Srifa, Gang Bao, Matthew H Porteus
Metabolic engineering generates a transgene-free safety switch for cell therapy. Nature biotechnology 38 (12) (2020)
Mara Pavel-Dinu, Volker Wiebking, Beruh T Dejene, Waracharee Srifa, Sruthi Mantri, Carmencita E Nicolas, Ciaran M Lee, Gang Bao, Eric J Kildebeck, Niraj Punjya, Camille Sindhu, Matthew A Inlay, Nivedita Saxena, Suk See DeRavin, Harry Malech, Maria Grazia Roncarolo, Kenneth I Weinberg, Matthew H Porteus
Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nature communications 10 (1) (2019)
Yu-Cheng Lee, Antonina V Kurtova, Jing Xiao, Fotis Nikolos, Kazukuni Hayashi, Zoe Tramel, Antrix Jain, Fengju Chen, Mithil Chokshi, Ciaran M Lee, Gang Bao, Xiang Zhang, Jianjun Shen, Qianxing Mo, Sung Yun Jung, David Rowley, Keith Syson Chan
Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung. Nature communications 10 (1) (2019)
Mara Pavel-Dinu, Volker Wiebking, Beruh T Dejene, Waracharee Srifa, Sruthi Mantri, Carmencita E Nicolas, Ciaran M Lee, Gang Bao, Eric J Kildebeck, Niraj Punjya, Camille Sindhu, Matthew A Inlay, Nivedita Saxena, Suk See DeRavin, Harry Malech, Maria Grazia Roncarolo, Kenneth I Weinberg, Matthew H Porteus
Author Correction: Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nature communications 10 (1) (2019)
Mara Pavel-Dinu, Volker Wiebking, Beruh T Dejene, Waracharee Srifa, Sruthi Mantri, Carmencita E Nicolas, Ciaran M Lee, Gang Bao, Eric J Kildebeck, Niraj Punjya, Camille Sindhu, Matthew A Inlay, Nivedita Saxena, Suk See DeRavin, Harry Malech, Maria Grazia Roncarolo, Kenneth I Weinberg, Matthew H Porteus
Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nature communications 10 (1) (2019)
Natalia Gomez-Ospina, Samantha G Scharenberg, Nathalie Mostrel, Rasmus O Bak, Sruthi Mantri, Rolen M Quadros, Channabasavaiah Basavaraju Gurumurthy, Ciaran M Lee, Gang Bao, Carlos J Suarez, Shaukat Khan, Kazuki Sawamoto, Shunji Tomatsu, Nitin Raj, Laura D Attardi, Laure Aurelian, Matthew H Porteus
Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I. Nature communications 10 (1) (2019)
Christopher A Vakulskas, Daniel P Dever, Garrett R Rettig, Rolf Turk, Ashley M Jacobi, Michael A Collingwood, Nicole M Bode, Matthew S McNeill, Shuqi Yan, Joab Camarena, Ciaran M Lee, So Hyun Park, Volker Wiebking, Rasmus O Bak, Natalia Gomez-Ospina, Mara Pavel-Dinu, Wenchao Sun, Gang Bao, Matthew H Porteus, Mark A Behlke
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells. Nature medicine 24 (8) (2018)
Haibao Zhu, Linlin Zhang, Sheng Tong, Ciaran M Lee, Harshavardhan Deshmukh, Gang Bao
Spatial control of in vivo CRISPR-Cas9 genome editing via nanomagnets. Nature biomedical engineering 3 (2) (2018)
Ciaran M Lee, Timothy H Davis, Gang Bao
Examination of CRISPR/Cas9 design tools and the effect of target site accessibility on Cas9 activity. Experimental physiology 103 (4) (2017)

Ciaran M Lee.css-eqlu8i{font-size:small;padding-left:4px;} (Ciaran Lee, E Lee)

Publication Activity (10 Years)

Top Topics

Top Venues

Ciaran M Lee (Ciaran Lee, E Lee)