Rasmus O Bak (R O Bak)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 35

Top Venues

Communications biology

Nature communications

eLife

Leukemia

Aarhus University

Aarhus Universitet (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Aarhus University Aug 01 2018

Denmark

Associate Professor :: Aarhus Institute of Advanced Studies

Aarhus University Oct 01 2017 - Aug 01 2018

Denmark

Assistant Professor :: Aarhus Institute of Advanced Studies (AIAS)

Stanford University Aug 01 2014 - Aug 01 2017

United States

Postdoctoral Research Fellow :: Dept. of Pediatrics

Education History

Aarhus Universitet

Denmark

PHD :: Dept. of Biomedicine

Aarhus Universitet - Mar 19 2010

Denmark

MSC

Aarhus Universitet Aug 20 2004

Denmark

BSC

Publications

Chaochao Chai, Langchao Liang, Nanna S Mikkelsen, Wei Wang, Wandong Zhao, Chengcheng Sun, Rasmus O Bak, Hanbo Li, Lin Lin, Fei Wang, Yonglun Luo
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer. Communications biology 7 (1) (2024)
Chaochao Chai, Langchao Liang, Nanna S Mikkelsen, Wei Wang, Wandong Zhao, Chengcheng Sun, Rasmus O Bak, Hanbo Li, Lin Lin, Fei Wang, Yonglun Luo
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer. Communications biology 7 (1) (2024)
Huiqiang Cai, Bin Zhang, Johanne Ahrenfeldt, Justin V Joseph, Maria Riedel, Zongliang Gao, Sofie K Thomsen, Ditte S Christensen, Rasmus O Bak, Henrik Hager, Mikkel H Vendelbo, Xin Gao, Nicolai Juul Birkbak, Martin K Thomsen
CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression. Nature communications 15 (1) (2024)
Huiqiang Cai, Bin Zhang, Johanne Ahrenfeldt, Justin V Joseph, Maria Riedel, Zongliang Gao, Sofie K Thomsen, Ditte S Christensen, Rasmus O Bak, Henrik Hager, Mikkel H Vendelbo, Xin Gao, Nicolai Juul Birkbak, Martin K Thomsen
CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression. Nature communications 15 (1) (2024)
Demi van der Horst, Naziia Kurmasheva, Mikkel H S Marqvorsen, Sonia Assil, Anna Halling Folkmar Andersen, Christoph F Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B Iversen, Fanghui Ren, Trine I Jensen, Ryo Narita, Vivien R Schack, Bao-Cun Zhang, Rasmus O Bak, Claudio Sette, Robert A Fenton, Jacob G Mikkelsen, Soren Riis Paludan, David Olagnier
SAM68 directs STING signaling to apoptosis in macrophages. Communications biology 7 (1) (2024)
Chaochao Chai, Langchao Liang, Nanna S Mikkelsen, Wei Wang, Wandong Zhao, Chengcheng Sun, Rasmus O Bak, Hanbo Li, Lin Lin, Fei Wang, Yonglun Luo
Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancer. Communications biology 7 (1) (2024)
Huiqiang Cai, Bin Zhang, Johanne Ahrenfeldt, Justin V Joseph, Maria Riedel, Zongliang Gao, Sofie K Thomsen, Ditte S Christensen, Rasmus O Bak, Henrik Hager, Mikkel H Vendelbo, Xin Gao, Nicolai Juul Birkbak, Martin K Thomsen
CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression. Nature communications 15 (1) (2024)
Demi van der Horst, Naziia Kurmasheva, Mikkel H S Marqvorsen, Sonia Assil, Anna Halling Folkmar Andersen, Christoph F Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B Iversen, Fanghui Ren, Trine I Jensen, Ryo Narita, Vivien R Schack, Bao-Cun Zhang, Rasmus O Bak, Claudio Sette, Robert A Fenton, Jacob G Mikkelsen, Soren Riis Paludan, David Olagnier
SAM68 directs STING signaling to apoptosis in macrophages. Communications biology 7 (1) (2024)
Huiqiang Cai, Bin Zhang, Johanne Ahrenfeldt, Justin V Joseph, Maria Riedel, Zongliang Gao, Sofie K Thomsen, Ditte S Christensen, Rasmus O Bak, Henrik Hager, Mikkel H Vendelbo, Xin Gao, Nicolai Juul Birkbak, Martin K Thomsen
CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression. Nature communications 15 (1) (2024)
Demi van der Horst, Naziia Kurmasheva, Mikkel H S Marqvorsen, Sonia Assil, Anna Halling Folkmar Andersen, Christoph F Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B Iversen, Fanghui Ren, Trine I Jensen, Ryo Narita, Vivien R Schack, Bao-Cun Zhang, Rasmus O Bak, Claudio Sette, Robert A Fenton, Jacob G Mikkelsen, Soren Riis Paludan, David Olagnier
SAM68 directs STING signaling to apoptosis in macrophages. Communications biology 7 (1) (2024)
Demi van der Horst, Naziia Kurmasheva, Mikkel H S Marqvorsen, Sonia Assil, Anna Halling Folkmar Andersen, Christoph F Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B Iversen, Fanghui Ren, Trine I Jensen, Ryo Narita, Vivien R Schack, Bao-Cun Zhang, Rasmus O Bak, Claudio Sette, Robert A Fenton, Jacob G Mikkelsen, Soren Riis Paludan, David Olagnier
SAM68 directs STING signaling to apoptosis in macrophages. Communications biology 7 (1) (2024)
Francisco Xavier Galdos, Carissa Lee, Soah Lee, Sharon Paige, William Goodyer, Sidra Xu, Tahmina Samad, Gabriela V Escobar, Adrija Darsha, Aimee Beck, Rasmus O Bak, Matthew H Porteus, Sean M Wu
Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation. eLife 12 (2023)
Fanghui Ren, Ryo Narita, Ahmad S Rashidi, Stefanie Fruhwürth, Zongliang Gao, Rasmus O Bak, Martin K Thomsen, Georges G M G M Verjans, Line S Reinert, Soren Riis Paludan
ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2. The EMBO journal (2023)
Eileen Wedge, Ulvi Ahmadov, Thomas B Hansen, Zongliang Gao, Morten Tulstrup, Christophe Rm Côme, Sridhar Nonavinkere Srivatsan, Tanzir Ahmed, Jakob Schmidt Jespersen, Balthasar Clemens Schlotmann, Claudia Schöllkopf, Klas Raaschou-Jensen, Niels Ødum, Jørgen Kjems, Rasmus O Bak, Matthew J Walter, Kirsten Grønbaek, Lasse Sommer Kristensen
Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms. Leukemia (2023)
Eileen Wedge, Ulvi Ahmadov, Thomas B Hansen, Zongliang Gao, Morten Tulstrup, Christophe Rm Côme, Sridhar Nonavinkere Srivatsan, Tanzir Ahmed, Jakob Schmidt Jespersen, Balthasar Clemens Schlotmann, Claudia Schöllkopf, Klas Raaschou-Jensen, Niels Ødum, Jørgen Kjems, Rasmus O Bak, Matthew J Walter, Kirsten Grønbaek, Lasse Sommer Kristensen
Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms. Leukemia (2023)
Signe Neldeborg, Johannes Frasez Soerensen, Charlotte Thornild Møller, Marie Bill, Zongliang Gao, Rasmus O Bak, Kasper Holm, Boe Sandahl Sørensen, Mette Nygaard, Yonglun Luo, Peter Hokland, Magnus Stougaard, Maja Ludvigsen, Christian Kanstrup Holm
Dual intron-targeted CRISPR-Cas9-mediated disruption of the AML RUNX1-RUNX1T1 fusion gene effectively inhibits proliferation and decreases tumor volume in vitro and in vivo. Leukemia (2023)
Nanna S Mikkelsen, Rasmus O Bak
Enrichment strategies to enhance genome editing. Journal of biomedical science 30 (1) (2023)
Nanna S Mikkelsen, Rasmus O Bak
Enrichment strategies to enhance genome editing. Journal of biomedical science 30 (1) (2023)
Frederik Holm Rothemejer, Nanna Pi Lauritsen, Anna Karina Juhl, Mariane Høgsbjerg Schleimann, Saskia König, Ole Schmeltz Søgaard, Rasmus O Bak, Martin Tolstrup
Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus. Viruses 15 (1) (2023)
Frederik Holm Rothemejer, Nanna Pi Lauritsen, Anna Karina Juhl, Mariane Høgsbjerg Schleimann, Saskia König, Ole Schmeltz Søgaard, Rasmus O Bak, Martin Tolstrup
Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus. Viruses 15 (1) (2023)
Frederik Holm Rothemejer, Nanna Pi Lauritsen, Anna Karina Juhl, Mariane Høgsbjerg Schleimann, Saskia König, Ole Schmeltz Søgaard, Rasmus O Bak, Martin Tolstrup
Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus. Viruses 15 (1) (2023)
Maya Graham Pedersen, Bjarne Kuno Møller, Rasmus O Bak
Recent Advances in the Development of Anti-FLT3 CAR T-Cell Therapies for Treatment of AML. Biomedicines 10 (10) (2022)
Sabina Sánchez Hernández, Martin Roelsgaard Jakobsen, Rasmus O Bak
Plasmacytoid Dendritic Cells as a Novel Cell-Based Cancer Immunotherapy. International journal of molecular sciences 23 (19) (2022)
Renée M van der Sluis, Lamin B Cham, Albert Gris-Oliver, Kristine R Gammelgaard, Jesper G Pedersen, Manja Idorn, Ulvi Ahmadov, Sabina Sanches Hernandez, Ena Cémalovic, Stine H Godsk, Jacob Thyrsted, Jesper Damsgaard Gunst, Silke D Nielsen, Janni J Jørgensen, Tobias Wang Bjerg, Anders Laustsen, Line S Reinert, David Olagnier, Rasmus O Bak, Mads Kjolby, Christian Kanstrup Holm, Martin Tolstrup, Soren Riis Paludan, Lasse S Kristensen, Ole Schmeltz Søgaard, Martin Roelsgaard Jakobsen
TLR2 and TLR7 mediate distinct immunopathological and antiviral plasmacytoid dendritic cell responses to SARS-CoV-2 infection. The EMBO journal 41 (10) (2022)
Anders Laustsen, Renée M van der Sluis, Albert Gris-Oliver, Sabina Sánchez Hernández, Ena Cemalovic, Hai Q Tang, Lars Henning Pedersen, Niels Uldbjerg, Martin Roelsgaard Jakobsen, Rasmus O Bak
Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells. eLife 10 (2021)
Trine I Jensen, Nanna S Mikkelsen, Zongliang Gao, Johannes Foßelteder, Gabriel Pabst, Esben Axelgaard, Anders Laustsen, Saskia König, Andreas Reinisch, Rasmus O Bak
Targeted regulation of transcription in primary cells using CRISPRa and CRISPRi. Genome research 31 (11) (2021)
M Kyle Cromer, Joab Camarena, Renata M Martin, Benjamin J Lesch, Christopher A Vakulskas, Nicole M Bode, Gavin L Kurgan, Michael A Collingwood, Garrett R Rettig, Mark A Behlke, Viktor T Lemgart, Yankai Zhang, Ankush Goyal, Feifei Zhao, Ezequiel Ponce, Waracharee Srifa, Rasmus O Bak, Naoya Uchida, Ravindra Majeti, Vivien A Sheehan, John F Tisdale, Daniel P Dever, Matthew H Porteus
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells. Nature medicine 27 (4) (2021)
Bao-Cun Zhang, Ramya Nandakumar, Line S Reinert, Jinrong Huang, Anders Laustsen, Zong-Liang Gao, Cheng-Long Sun, Søren Beck Jensen, Anne Troldborg, Sonia Assil, Martin F Berthelsen, Carsten Scavenius, Yan Zhang, Samuel J Windross, David Olagnier, Thaneas Prabakaran, Chiranjeevi Bodda, Ryo Narita, Yujia Cai, Cong-Gang Zhang, Harald Alfred Stenmark, Christine M Doucet, Takeshi Noda, Zheng Guo, Raphaela Goldbach-Mansky, Rune Hartmann, Zhijian J Chen, Jan J Enghild, Rasmus O Bak, Martin K Thomsen, Soren Riis Paludan
STEEP mediates STING ER exit and activation of signaling. Nature immunology 21 (8) (2020)
Trine I Jensen, Esben Axelgaard, Rasmus O Bak
Therapeutic gene editing in haematological disorders with CRISPR/Cas9. British journal of haematology 185 (5) (2019)
Natalia Gomez-Ospina, Samantha G Scharenberg, Nathalie Mostrel, Rasmus O Bak, Sruthi Mantri, Rolen M Quadros, Channabasavaiah Basavaraju Gurumurthy, Ciaran M Lee, Gang Bao, Carlos J Suarez, Shaukat Khan, Kazuki Sawamoto, Shunji Tomatsu, Nitin Raj, Laura D Attardi, Laure Aurelian, Matthew H Porteus
Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I. Nature communications 10 (1) (2019)
Christopher A Vakulskas, Daniel P Dever, Garrett R Rettig, Rolf Turk, Ashley M Jacobi, Michael A Collingwood, Nicole M Bode, Matthew S McNeill, Shuqi Yan, Joab Camarena, Ciaran M Lee, So Hyun Park, Volker Wiebking, Rasmus O Bak, Natalia Gomez-Ospina, Mara Pavel-Dinu, Wenchao Sun, Gang Bao, Matthew H Porteus, Mark A Behlke
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells. Nature medicine 24 (8) (2018)
Rasmus O Bak, Daniel P Dever, Andreas Reinisch, David Cruz Hernandez, Ravindra Majeti, Matthew H Porteus
Correction: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. eLife 7 (2018)
A Laustsen, Rasmus O Bak, C Krapp, L Kjær, J H Egedahl, C C Petersen, S Pillai, H Q Tang, N Uldbjerg, M Porteus, N R Roan, Mette Nyegaard, Paul W Denton, Martin Roelsgaard Jakobsen
Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function. Nature communications 9 (1) (2018)
Rasmus O Bak, Daniel P Dever, Matthew H Porteus
CRISPR/Cas9 genome editing in human hematopoietic stem cells. Nature protocols 13 (2) (2018)
Rasmus O Bak, Daniel P Dever, Andreas Reinisch, David Cruz Hernandez, Ravindra Majeti, Matthew H Porteus
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. eLife 6 (2017)

Rasmus O Bak.css-eqlu8i{font-size:small;padding-left:4px;} (R O Bak)

Publication Activity (10 Years)

Top Topics

Top Venues

Rasmus O Bak (R O Bak)