Chunlai Chen

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Topics

High Efficiency

Single Molecule

Top Venues

Nucleic acids research

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Wenjing Xing, Danyuan Li, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET. Nucleic acids research 52 (15) (2024)
Weifeng Zhang, Lingling Cheng, Kuan Li, Leiming Xie, Jinyao Ji, Xue Lei, Anjie Jiang, Chunlai Chen, Haitao Li, Pilong Li, Qianwen Sun
Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants. Nature plants 10 (8) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Shouyue Zhang, Ao Sun, Jing-Mei Qian, Shuo Lin, Wenjing Xing, Yun Yang, Han-Zhou Zhu, Xin-Yi Zhou, Yan-Shuo Guo, Yun Liu, Yu Meng, Shu-Lin Jin, Wenhao Song, Cheng-Ping Li, Zhaofu Li, Shuai Jin, Jian-Hua Wang, Meng-Qiu Dong, Caixia Gao, Chunlai Chen, Yang Bai, Jun-Jie Gogo Liu
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature (2024)
Shouyue Zhang, Ao Sun, Jing-Mei Qian, Shuo Lin, Wenjing Xing, Yun Yang, Han-Zhou Zhu, Xin-Yi Zhou, Yan-Shuo Guo, Yun Liu, Yu Meng, Shu-Lin Jin, Wenhao Song, Cheng-Ping Li, Zhaofu Li, Shuai Jin, Jian-Hua Wang, Meng-Qiu Dong, Caixia Gao, Chunlai Chen, Yang Bai, Jun-Jie Gogo Liu
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature 630 (8016) (2024)
Shouyue Zhang, Ao Sun, Jing-Mei Qian, Shuo Lin, Wenjing Xing, Yun Yang, Han-Zhou Zhu, Xin-Yi Zhou, Yan-Shuo Guo, Yun Liu, Yu Meng, Shu-Lin Jin, Wenhao Song, Cheng-Ping Li, Zhaofu Li, Shuai Jin, Jian-Hua Wang, Meng-Qiu Dong, Caixia Gao, Chunlai Chen, Yang Bai, Jun-Jie Gogo Liu
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature 630 (8016) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Weifeng Zhang, Lingling Cheng, Kuan Li, Leiming Xie, Jinyao Ji, Xue Lei, Anjie Jiang, Chunlai Chen, Haitao Li, Pilong Li, Qianwen Sun
Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants. Nature plants 10 (8) (2024)
Shouyue Zhang, Ao Sun, Jing-Mei Qian, Shuo Lin, Wenjing Xing, Yun Yang, Han-Zhou Zhu, Xin-Yi Zhou, Yan-Shuo Guo, Yun Liu, Yu Meng, Shu-Lin Jin, Wenhao Song, Cheng-Ping Li, Zhaofu Li, Shuai Jin, Jian-Hua Wang, Meng-Qiu Dong, Caixia Gao, Chunlai Chen, Yang Bai, Jun-Jie Gogo Liu
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature 630 (8016) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Weifeng Zhang, Lingling Cheng, Kuan Li, Leiming Xie, Jinyao Ji, Xue Lei, Anjie Jiang, Chunlai Chen, Haitao Li, Pilong Li, Qianwen Sun
Evolutional heterochromatin condensation delineates chromocenter formation and retrotransposon silencing in plants. Nature plants (2024)
Shouyue Zhang, Ao Sun, Jing-Mei Qian, Shuo Lin, Wenjing Xing, Yun Yang, Han-Zhou Zhu, Xin-Yi Zhou, Yan-Shuo Guo, Yun Liu, Yu Meng, Shu-Lin Jin, Wenhao Song, Cheng-Ping Li, Zhaofu Li, Shuai Jin, Jian-Hua Wang, Meng-Qiu Dong, Caixia Gao, Chunlai Chen, Yang Bai, Jun-Jie Gogo Liu
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Wenjing Xing, Danyuan Li, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET. Nucleic acids research 52 (15) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Wenjing Xing, Danyuan Li, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET. Nucleic acids research 52 (15) (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Elizabeth White, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Ligand efficacy modulates conformational dynamics of the µ-opioid receptor. Nature 629 (8011) (2024)
Wenjing Xing, Danyuan Li, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Conformational dynamics of CasX (Cas12e) in mediating DNA cleavage revealed by single-molecule FRET. Nucleic acids research (2024)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Jie Heng, Yunfei Hu, Guillermo Pérez Hernández, Asuka Inoue, Jiawei Zhao, Xiuyan Ma, Xiaoou Sun, Kouki Kawakami, Tatsuya Ikuta, Jienv Ding, Yujie Yang, Lujia Zhang, Sijia Peng, Xiaogang Niu, Hongwei Li, Ramon Guixà-Gonzaléz, Changwen Jin, Peter W Hildebrand, Chunlai Chen, Brian K Kobilka
Function and dynamics of the intrinsically disordered carboxyl terminus of β2 adrenergic receptor. Nature communications 14 (1) (2023)
Ruirui Sun, Yuqian Zhao, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Nonspecific interactions between Cas12a and dsDNA located downstream of the PAM mediate target search and assist AsCas12a for DNA cleavage. Chemical science 14 (14) (2023)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Jiaxin Zhang, Lili Li, Yu Miao, Xiaojing Liu, Haitao Sun, Meiqian Jiang, Xiaoli Li, Zhen Li, Cong Liu, Bao-Hua Liu, Xingzhi Xu, Qinhong Cao, Wenya Hou, Chunlai Chen, Huiqiang Lou
Symmetric control of sister chromatid cohesion establishment. Nucleic acids research (2023)
Jiawei Zhao, Matthias Elgeti, Evan S O'Brien, Cecília P Sár, Amal Ei Daibani, Jie Heng, Xiaoou Sun, Tao Che, Wayne L Hubbell, Brian K Kobilka, Chunlai Chen
Conformational dynamics of the μ-opioid receptor determine ligand intrinsic efficacy. bioRxiv : the preprint server for biology (2023)
Xiaolin Niu, Zhonghe Xu, Yufan Zhang, Xiao-Bing Zuo, Chunlai Chen, Xian-Yang Fang
Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch. Nature communications 14 (1) (2023)
Tianlun Ding, Jinyao Ji, Weiying Zhang, Yuheng Liu, Boqi Liu, Yiyang Han, Chunlai Chen, Li Yu
The phosphatidylinositol (4,5)-bisphosphate-Rab35 axis regulates migrasome formation. Cell research (2023)
Yuan Zhang, Chen Yang, Sijia Peng, Jing Ling, Peng Chen, Yumiao Ma, Wenjuan Wang, Zhixing Chen, Chunlai Chen
General Strategy To Improve the Photon Budget of Thiol-Conjugated Cyanine Dyes. Journal of the American Chemical Society (2023)
Zhichao Du, Wenjing Wang, Siyuan Luo, Lingjie Zhang, Shuowei Yuan, Yongzhen Hei, Zhangbin Bao, Chunlai Chen, Yi Lin, Ling Chu
Self-Renewable Tag for Photostable Fluorescence Imaging of Proteins. Journal of the American Chemical Society (2023)
Yirong Yao, Wenjuan Wang, Chunlai Chen
Mechanisms of phase-separation-mediated cGAS activation revealed by dcFCCS. PNAS nexus 1 (3) (2022)
Yirong Yao, Wenjuan Wang, Chunlai Chen
Mechanisms of phase-separation-mediated cGAS activation revealed by dcFCCS. PNAS nexus 1 (3) (2022)
Yanping Hu, Yan Wang, Jaideep Singh, Ruirui Sun, Lilei Xu, Xiaolin Niu, Keyun Huang, Guangcan Bai, Guoquan Liu, Xiaobing Zuo, Chunlai Chen, Peter Z Qin, Xian-Yang Fang
Phosphorothioate-Based Site-Specific Labeling of Large RNAs for Structural and Dynamic Studies. ACS chemical biology 17 (9) (2022)
Jingfei Xu, Lingyun Zhao, Sijia Peng, Huiying Chu, Rui Liang, Meng Tian, Philip P Connell, Guohui Li, Chunlai Chen, Hong-Wei Wang
Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination. Nucleic acids research (2021)
Mengyi Yang, Ruirui Sun, Pujuan Deng, Yuzhuo Yang, Wenjuan Wang, Jun-Jie Gogo Liu, Chunlai Chen
Nonspecific interactions between SpCas9 and dsDNA sites located downstream of the PAM mediate facilitated diffusion to accelerate target search. Chemical science 12 (38) (2021)
Sijia Peng, Xiaowei Wang, Lu Zhang, Shanshan He, Xin Sheng Zhao, Xuhui Huang, Chunlai Chen
Target search and recognition mechanisms of glycosylase AlkD revealed by scanning FRET-FCS and Markov state models. Proceedings of the National Academy of Sciences of the United States of America 117 (36) (2020)
Sijia Peng, Weiping Li, Yirong Yao, Wenjing Xing, Pilong Li, Chunlai Chen
Phase separation at the nanoscale quantified by dcFCCS. Proceedings of the National Academy of Sciences of the United States of America 117 (44) (2020)
Bin Liu, Chunlai Chen
Retraction for Liu and Chen, "Translation Elongation Factor 4 (LepA) Contributes to Tetracycline Susceptibility by Stalling Elongating Ribosomes". Antimicrobial agents and chemotherapy 63 (2) (2019)
Shanshan He, Chen Yang, Sijia Peng, Chunlai Chen, Xin Sheng Zhao
Single-molecule study on conformational dynamics of M.HhaI. RSC advances 9 (26) (2019)
Sijia Peng, Mengyi Yang, Rui Ning Sun, Yang Liu, Wenjuan Wang, Qiaoran Xi, Haipeng Gong, Chunlai Chen
Mechanism of actions of Oncocin, a proline-rich antimicrobial peptide, in early elongation revealed by single-molecule FRET. Protein & cell 9 (10) (2019)
Bin Liu, Chunlai Chen
Translation Elongation Factor 4 (LepA) Contributes to Tetracycline Susceptibility by Stalling Elongating Ribosomes. Antimicrobial agents and chemotherapy 62 (8) (2018)
Sijia Peng, Wenjuan Wang, Chunlai Chen
Surface Transient Binding-Based Fluorescence Correlation Spectroscopy (STB-FCS), a Simple and Easy-to-Implement Method to Extend the Upper Limit of the Time Window to Seconds. The journal of physical chemistry. B 122 (18) (2018)
Sijia Peng, Ruirui Sun, Wenjuan Wang, Chunlai Chen
Single-Molecule Photoactivation FRET: A General and Easy-To-Implement Approach To Break the Concentration Barrier. Angewandte Chemie (International ed. in English) 56 (24) (2017)
Sijia Peng, Wenjuan Wang, Chunlai Chen
Breaking the Concentration Barrier for Single-Molecule Fluorescence Measurements. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (5) (2017)