Daniel Scotcher

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 16

Top Topics

Emergency Department

Diffusion Weighted Imaging

Chronic Kidney Disease

Top Venues

Clinical pharmacology and therapeutics

CPT: pharmacometrics & systems pharmacology

Molecular pharmaceutics

This page only lists publications with an associated author ORCID identifier.

Publications

Shawn Pei Feng Tan, Annika Tillmann, Susan J Murby, Amin Rostami-Hodjegan, Daniel Scotcher, Aleksandra Galetin
Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance. Molecular pharmaceutics 21 (9) (2024)
Shawn Pei Feng Tan, Annika Tillmann, Susan J Murby, Amin Rostami-Hodjegan, Daniel Scotcher, Aleksandra Galetin
Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance. Molecular pharmaceutics (2024)
Nicola Melillo, Daniel Scotcher, J Gerry Kenna, Claudia Green, Catherine D G Hines, Iina Laitinen, Paul D Hockings, Kayode Ogungbenro, Ebony R Gunwhy, Steven Sourbron, John Charles Waterton, Gunnar Schuetz, Aleksandra Galetin
Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats. Pharmaceutics 15 (3) (2023)
Shawn Pei Feng Tan, Marie-Emilie Willemin, Jan Snoeys, Hong Shen, Amin Rostami-Hodjegan, Daniel Scotcher, Aleksandra Galetin
Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker-Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease. Clinical pharmacology and therapeutics (2023)
Nihan Izat, Jayaprakasam Bolleddula, Armina Abbasi, Lionel Cheruzel, Robert S Jones, Darren Moss, Fatima Ortega-Muro, Yannick Parmentier, Vincent C Peterkin, Dan-Dan Tian, Karthik Venkatakrishnan, Michael A Zientek, Jill Barber, J Brian Houston, Aleksandra Galetin, Daniel Scotcher
Challenges and opportunities for in vitro-in vivo extrapolation of aldehyde oxidase-mediated clearance: Towards a roadmap for quantitative translation. Drug metabolism and disposition: the biological fate of chemicals (2023)
Nicola Melillo, Daniel Scotcher, J Gerry Kenna, Claudia Green, Catherine D G Hines, Iina Laitinen, Paul D Hockings, Kayode Ogungbenro, Ebony R Gunwhy, Steven Sourbron, John Charles Waterton, Gunnar Schuetz, Aleksandra Galetin
Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats. Pharmaceutics 15 (3) (2023)
Nicola Melillo, Daniel Scotcher, J Gerry Kenna, Claudia Green, Catherine D G Hines, Iina Laitinen, Paul D Hockings, Kayode Ogungbenro, Ebony R Gunwhy, Steven Sourbron, John Charles Waterton, Gunnar Schuetz, Aleksandra Galetin
Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug-Drug Interactions in Rats. Pharmaceutics 15 (3) (2023)
Hiroyuki Takita, Daniel Scotcher, Xiaoyan Chu, Ka Lai Yee, Kayode Ogungbenro, Aleksandra Galetin
Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease. Clinical pharmacology and therapeutics 112 (3) (2022)
Shawn Pei Feng Tan, Daniel Scotcher, Amin Rostami-Hodjegan, Aleksandra Galetin
Effect of Chronic Kidney Disease on the Renal Secretion via Organic Anion Transporters 1/3: Implications for Physiologically-Based Pharmacokinetic Modeling and Dose Adjustment. Clinical pharmacology and therapeutics 112 (3) (2022)
Daniel Scotcher, Nicola Melillo, Sirisha Tadimalla, Adam S Darwich, Sabina Ziemian, Kayode Ogungbenro, Gunnar Schütz, Steven Sourbron, Aleksandra Galetin
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in Rats. Molecular pharmaceutics 18 (8) (2021)
Zubida M Al-Majdoub, Daniel Scotcher, Brahim Achour, Jill Barber, Aleksandra Galetin, Amin Rostami-Hodjegan
Quantitative Proteomic Map of Enzymes and Transporters in the Human Kidney: Stepping Closer to Mechanistic Kidney Models to Define Local Kinetics. Clinical pharmacology and therapeutics 110 (5) (2021)
Hiroyuki Takita, Daniel Scotcher, Rajkumar Chinnadurai, Philip A Kalra, Aleksandra Galetin
Physiologically-Based Pharmacokinetic Modelling of Creatinine-Drug Interactions in the Chronic Kidney Disease Population. CPT: pharmacometrics & systems pharmacology 9 (12) (2020)
Daniel Scotcher, Vikram Arya, Xinning Yang, Ping Zhao, Lei Zhang, Shiew Mei Huang, Amin Rostami-Hodjegan, Aleksandra Galetin
A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations. CPT: pharmacometrics & systems pharmacology 9 (6) (2020)
Eman El-Khateeb, Brahim Achour, Daniel Scotcher, Zubida M Al-Majdoub, Varinder S Athwal, Jill Barber, Amin Rostami-Hodjegan
Scaling Factors for Clearance in Adult Liver Cirrhosis. Drug metabolism and disposition: the biological fate of chemicals 48 (12) (2020)
Daniel Scotcher, Vikram Arya, Xinning Yang, Ping Zhao, Lei Zhang, Shiew Mei Huang, Amin Rostami-Hodjegan, Aleksandra Galetin
Mechanistic Models as Framework for Understanding Biomarker Disposition: Prediction of Creatinine-Drug Interactions. CPT: pharmacometrics & systems pharmacology 9 (5) (2020)
Takanobu Matsuzaki, Daniel Scotcher, Adam S Darwich, Aleksandra Galetin, Amin Rostami-Hodjegan
Towards Further Verification of Physiologically-Based Kidney Models: Predictability of the Effects of Urine-Flow and Urine-pH on Renal Clearance. The Journal of pharmacology and experimental therapeutics 368 (2) (2018)