Sandra Gemma

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 36

Top Venues

Journal of medicinal chemistry

Molecules (Basel, Switzerland)

ACS infectious diseases

ChemMedChem

Università degli Studi di Siena

Università degli Studi di Siena (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Università degli Studi di Siena Apr 01 2016

Italy

Professore Associato :: Dipartimento di Biotecnologie, Chimica e Farmacia

Università degli Studi di Siena Mar 01 2006 - Mar 31 2016

Italy

Ricercatore :: Department of Biotechnology, Chemistry and Pharmacy

University of Illinois at Chicago

United States

Post-doctoral fellow :: Department of Chemistry

Education History

Università degli Studi di Siena

Italy

PHD :: Dipartimento Farmaco-Chimico-Tecnologco

Publications

Sara Rossi, Valeria Tudino, Gabriele Carullo, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma . ACS infectious diseases 10 (5) (2024)
Federica Falbo, Sandra Gemma, Adrian Koch, Sarah Mazzotta, Gabriele Carullo, Anna Ramunno, Stefania Butini, Regine Schneider-Stock, Giuseppe Campiani, Francesca Aiello
Synthetic derivatives of natural cinnamic acids as potential anti-colorectal cancer agents. Chemical biology & drug design 103 (1) (2024)
Stefania Butini, Uwe Grether, Kwang-Mook Jung, Alessia Ligresti, Marco Allarà, Annemarieke G J Postmus, Samuele Maramai, Simone Brogi, Alessandro Papa, Gabriele Carullo, David Sykes, Dmitry B Veprintsev, Stefano Federico, Alessandro Grillo, Bruno Di Guglielmo, Anna Ramunno, Anna Floor Stevens, Dominik Heer, Stefania Lamponi, Sandra Gemma, Jörg Benz, Vincenzo Di Marzo, Mario van der Stelt, Daniele Piomelli, Giuseppe Campiani
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of medicinal chemistry 67 (3) (2024)
Sara Rossi, Valeria Tudino, Gabriele Carullo, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma . ACS infectious diseases 10 (5) (2024)
Gabriele Carullo, Noemi Orsini, Ilaria Piano, Luca Pozzetti, Alessandro Papa, Anna Fontana, Debora Napoli, Francesca Corsi, Beatrice Di Marco, Alessia Galante, Ludovica Marotta, Giovanna Panzeca, Justine O'Brien, Alicia Gomez Sanchez, Harry Doherty, Niamh Mahon, Leni Clarke, Chiara Contri, Silvia Pasquini, Beatrice Gorelli, Simona Saponara, Massimo Valoti, Fabrizio Vincenzi, Katia Varani, Anna Ramunno, Simone Brogi, Stefania Butini, Sandra Gemma, Breandán N Kennedy, Claudia Gargini, Enrica Strettoi, Giuseppe Campiani
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy. Journal of medicinal chemistry (2024)
Stefania Butini, Uwe Grether, Kwang-Mook Jung, Alessia Ligresti, Marco Allarà, Annemarieke G J Postmus, Samuele Maramai, Simone Brogi, Alessandro Papa, Gabriele Carullo, David Sykes, Dmitry B Veprintsev, Stefano Federico, Alessandro Grillo, Bruno Di Guglielmo, Anna Ramunno, Anna Floor Stevens, Dominik Heer, Stefania Lamponi, Sandra Gemma, Jörg Benz, Vincenzo Di Marzo, Mario van der Stelt, Daniele Piomelli, Giuseppe Campiani
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of medicinal chemistry 67 (3) (2024)
Sara Rossi, Valeria Tudino, Gabriele Carullo, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma . ACS infectious diseases 10 (5) (2024)
Stefania Butini, Uwe Grether, Kwang-Mook Jung, Alessia Ligresti, Marco Allarà, Annemarieke G J Postmus, Samuele Maramai, Simone Brogi, Alessandro Papa, Gabriele Carullo, David Sykes, Dmitry B Veprintsev, Stefano Federico, Alessandro Grillo, Bruno Di Guglielmo, Anna Ramunno, Anna Floor Stevens, Dominik Heer, Stefania Lamponi, Sandra Gemma, Jörg Benz, Vincenzo Di Marzo, Mario van der Stelt, Daniele Piomelli, Giuseppe Campiani
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of medicinal chemistry 67 (3) (2024)
Stefania Butini, Uwe Grether, Kwang-Mook Jung, Alessia Ligresti, Marco Allarà, Annemarieke G J Postmus, Samuele Maramai, Simone Brogi, Alessandro Papa, Gabriele Carullo, David Sykes, Dmitry B Veprintsev, Stefano Federico, Alessandro Grillo, Bruno Di Guglielmo, Anna Ramunno, Anna Floor Stevens, Dominik Heer, Stefania Lamponi, Sandra Gemma, Jörg Benz, Vincenzo Di Marzo, Mario van der Stelt, Daniele Piomelli, Giuseppe Campiani
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of medicinal chemistry (2024)
Gabriele Carullo, Sara Rossi, Valentina Giudice, Alex Pezzotta, Ugo Chianese, Pasqualina Scala, Sabrina Carbone, Anna Fontana, Giovanna Panzeca, Silvia Pasquini, Chiara Contri, Sandra Gemma, Anna Ramunno, Simona Saponara, Francesca Galvani, Alessio Lodola, Marco Mor, Rosaria Benedetti, Carmine Selleri, Katia Varani, Stefania Butini, Lucia Altucci, Fabrizio Vincenzi, Anna Pistocchi, Giuseppe Campiani
Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies. ACS pharmacology & translational science 7 (7) (2024)
Federica Falbo, Sandra Gemma, Adrian Koch, Sarah Mazzotta, Gabriele Carullo, Anna Ramunno, Stefania Butini, Regine Schneider-Stock, Giuseppe Campiani, Francesca Aiello
Synthetic derivatives of natural cinnamic acids as potential anti-colorectal cancer agents. Chemical biology & drug design 103 (1) (2024)
Stefania Butini, Uwe Grether, Kwang-Mook Jung, Alessia Ligresti, Marco Allarà, Annemarieke G J Postmus, Samuele Maramai, Simone Brogi, Alessandro Papa, Gabriele Carullo, David Sykes, Dmitry B Veprintsev, Stefano Federico, Alessandro Grillo, Bruno Di Guglielmo, Anna Ramunno, Anna Floor Stevens, Dominik Heer, Stefania Lamponi, Sandra Gemma, Jörg Benz, Vincenzo Di Marzo, Mario van der Stelt, Daniele Piomelli, Giuseppe Campiani
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. Journal of medicinal chemistry 67 (3) (2024)
Gabriele Carullo, Sara Rossi, Valentina Giudice, Alex Pezzotta, Ugo Chianese, Pasqualina Scala, Sabrina Carbone, Anna Fontana, Giovanna Panzeca, Silvia Pasquini, Chiara Contri, Sandra Gemma, Anna Ramunno, Simona Saponara, Francesca Galvani, Alessio Lodola, Marco Mor, Rosaria Benedetti, Carmine Selleri, Katia Varani, Stefania Butini, Lucia Altucci, Fabrizio Vincenzi, Anna Pistocchi, Giuseppe Campiani
Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies. ACS pharmacology & translational science 7 (7) (2024)
Sara Rossi, Valeria Tudino, Gabriele Carullo, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Metalloenzyme Inhibitors against Zoonotic Infections: Focus on Leishmania and Schistosoma . ACS infectious diseases (2024)
Riccardo Fedeli, Ludovica Marotta, Luca Frattaruolo, Alice Panti, Gabriele Carullo, Fabio Fusi, Simona Saponara, Sandra Gemma, Stefania Butini, Anna Rita Cappello, Andrea Vannini, Giuseppe Campiani, Stefano Loppi
Nutritionally enriched tomatoes (Solanum lycopersicum L.) grown with wood distillate: chemical and biological characterization for quality assessment. Journal of food science (2023)
Gabriele Carullo, Giovanni Di Bonaventura, Sara Rossi, Veronica Lupetti, Valeria Tudino, Simone Brogi, Stefania Butini, Giuseppe Campiani, Sandra Gemma, Arianna Pompilio
Development of Quinazolinone Derivatives as Modulators of Virulence Factors of Pseudomonas aeruginosa Cystic Fibrosis Strains. Molecules (Basel, Switzerland) 28 (18) (2023)
Alessandro Papa, Silvia Pasquini, Chiara Contri, Sandra Gemma, Giuseppe Campiani, Stefania Butini, Katia Varani, Fabrizio Vincenzi
Polypharmacological Approaches for CNS Diseases: Focus on Endocannabinoid Degradation Inhibition. Cells 11 (3) (2022)
Simone Brogi, Roberta Ibba, Sara Rossi, Stefania Butini, Vincenzo Calderone, Sandra Gemma, Giuseppe Campiani
Covalent Reversible Inhibitors of Cysteine Proteases Containing the Nitrile Warhead: Recent Advancement in the Field of Viral and Parasitic Diseases. Molecules (Basel, Switzerland) 27 (8) (2022)
Julio Abel Alfredo Dos Santos Simone Come, Yibin Zhuang, Tianzhen Li, Simone Brogi, Sandra Gemma, Tao Liu, Edson Roberto da Silva
In Vitro and In Silico Analyses of New Cinnamid and Rosmarinic Acid-Derived Compounds Biosynthesized in Escherichia coli as Leishmania amazonensis Arginase Inhibitors. Pathogens (Basel, Switzerland) 11 (9) (2022)
Luca Pozzetti, Roberta Ibba, Sara Rossi, Taglialatela-Scafati Orazio, Donatella Taramelli, Nicoletta Basilico, Sarah D'Alessandro, Silvia Parapini, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity. Molecules (Basel, Switzerland) 27 (2) (2022)
Anna Fontana, Ilaria Cursaro, Gabriele Carullo, Sandra Gemma, Stefania Butini, Giuseppe Campiani
A Therapeutic Perspective of HDAC8 in Different Diseases: An Overview of Selective Inhibitors. International journal of molecular sciences 23 (17) (2022)
Theo Battista, Stefano Federico, Simone Brogi, Luca Pozzetti, Tuhina Khan, Stefania Butini, Anna Ramunno, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Annarita Fiorillo, Cécile Exertier, Daniel Di Risola, Gianni Colotti, Sandra Gemma, Andrea Ilari, Giuseppe Campiani
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach. ACS infectious diseases 8 (8) (2022)
Nicola Relitti, Akella Prasanth Saraswati, Gabriele Carullo, Alessandro Papa, Alessandra Monti, Rosaria Benedetti, Eugenia Passaro, Simone Brogi, Vincenzo Calderone, Stefania Butini, Sandra Gemma, Lucia Altucci, Giuseppe Campiani, Nunzianna Doti
Design and Synthesis of Oligopeptidic Parvulin Inhibitors. ChemMedChem 17 (11) (2022)
Luca Pozzetti, Maddalena Sguizzato, Ludovica Marotta, Sandra Gemma, Stefania Butini, Mascia Benedusi, Fabio Fusi, Amer Ahmed, Serena Pomponi, Stefano Ferrari, Matteo Perini, Anna Ramunno, Giacomo Pepe, Pietro Campiglia, Giuseppe Valacchi, Gabriele Carullo, Giuseppe Campiani
Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals. Antioxidants (Basel, Switzerland) 11 (3) (2022)
Alessandro Grillo, Filomena Fezza, Giulia Chemi, Roberto Colangeli, Simone Brogi, Domenico Fazio, Stefano Federico, Alessandro Papa, Nicola Relitti, Roberto Di Maio, Gianluca Giorgi, Stefania Lamponi, Massimo Valoti, Beatrice Gorelli, Simona Saponara, Mascia Benedusi, Alessandra Pecorelli, Patrizia Minetti, Giuseppe Valacchi, Stefania Butini, Giuseppe Campiani, Sandra Gemma, Mauro Maccarrone, Giuseppe Di Giovanni
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents. ACS chemical neuroscience 12 (9) (2021)
Giuseppe Campiani, Caterina Cavella, Jeremy D Osko, Margherita Brindisi, Nicola Relitti, Simone Brogi, A Prasanth Saraswati, Stefano Federico, Giulia Chemi, Samuele Maramai, Gabriele Carullo, Benedikt Jaeger, Alfonso Carleo, Rosaria Benedetti, Federica Sarno, Stefania Lamponi, Paola Rottoli, Elena Bargagli, Carlo Bertucci, Daniele Tedesco, Daniel Herp, Johanna Senger, Giovina Ruberti, Fulvio Saccoccia, Simona Saponara, Beatrice Gorelli, Massimo Valoti, Breandán N Kennedy, Husvinee Sundaramurthi, Stefania Butini, Manfred Jung, Katy M Roach, Lucia Altucci, Peter Bradding, David W Christianson, Sandra Gemma, Antje Prasse
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors. Journal of medicinal chemistry 64 (14) (2021)
Stefano Federico, Luca Pozzetti, Alessandro Papa, Gabriele Carullo, Sandra Gemma, Stefania Butini, Giuseppe Campiani, Nicola Relitti
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists. Journal of medicinal chemistry 63 (22) (2020)
Sandra Gemma
Structure-Based Design of Biologically Active Compounds. Molecules (Basel, Switzerland) 25 (14) (2020)
Gabriele Carullo, Stefano Federico, Nicola Relitti, Sandra Gemma, Stefania Butini, Giuseppe Campiani
Retinitis Pigmentosa and Retinal Degenerations: Deciphering Pathways and Targets for Drug Discovery and Development. ACS chemical neuroscience 11 (15) (2020)
Margherita Brindisi, A Prasanth Saraswati, Simone Brogi, Sandra Gemma, Stefania Butini, Giuseppe Campiani
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases. Journal of medicinal chemistry 63 (1) (2019)
Fulvio Saccoccia, Margherita Brindisi, Roberto Gimmelli, Nicola Relitti, Alessandra Guidi, A Prasanth Saraswati, Caterina Cavella, Simone Brogi, Giulia Chemi, Stefania Butini, Giuliana Papoff, Johanna Senger, Daniel Herp, Manfred Jung, Giuseppe Campiani, Sandra Gemma, Giovina Ruberti
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents. ACS infectious diseases 6 (1) (2019)
Jean Jacques Vanden Eynde, Arduino Aleksander Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A C Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Gennaro Chiappetta, Jean Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, Francisco Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, Maria Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdieroa, Hong Liu, Peter J H Scott, Cristóbal de Los Ríos, Luigi A Agrofoglio, Simona Collina, Rita C Guedes, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6. Molecules (Basel, Switzerland) 25 (1) (2019)
Arduino Aleksander Mangoni, Jean Jacques Vanden Eynde, Josef Jampilek, Dimitra Hadjipavlou-Litina, Hong Liu, Jóhannes Reynisson, Maria Emília Sousa, Paula A C Gomes, Katalin Prokai-Tatrai, Tiziano Tuccinardi, Jean Marc Sabatier, Francisco Javier Luque, Jarkko Rautio, Rafik Karaman, Maria Helena Vasconcelos, Sandra Gemma, Stefania Galdieroa, Christopher Hulme, Simona Collina, Michael Gütschow, George Kokotos, Carlo Siciliano, Raffaele Capasso, Luigi A Agrofoglio, Rino Ragno, Diego Muñoz-Torrero
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5. Molecules (Basel, Switzerland) 24 (13) (2019)
Basem Battah, Giulia Chemi, Stefania Butini, Giuseppe Campiani, Simone Brogi, Giovanni Delogu, Sandra Gemma
A Repurposing Approach for Uncovering the Anti-Tubercular Activity of FDA-Approved Drugs with Potential Multi-Targeting Profiles. Molecules (Basel, Switzerland) 24 (23) (2019)
Simone Brogi, Margherita Brindisi, Stefania Butini, Giridhar U Kshirsagar, Samuele Maramai, Giulia Chemi, Sandra Gemma, Giuseppe Campiani, Ettore Novellino, Paolo Fiorenzani, Jessica Pinassi, Anna Maria Aloisi, Mikko Gynther, Raminta Venskutonytė, Liwei Han, Karla Frydenvang, Jette Sandholm Kastrup, Darryl S Pickering
( S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation. Journal of medicinal chemistry 61 (5) (2018)
Marco Paolino, Margherita Brindisi, Alessandra Vallone, Stefania Butini, Giuseppe Campiani, Chiara Nannicini, Germano Giuliani, Maurizio Anzini, Stefania Lamponi, Gianluca Giorgi, Diego Sbardella, Davide M Ferraris, Stefano Marini, Massimo Coletta, Ivana Palucci, Mariachiara Minerva, Giovanni Delogu, Ilaria Pepponi, Delia Goletti, Andrea Cappelli, Sandra Gemma, Simone Brogi
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages. ChemMedChem 13 (5) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Sandra Gemma