Jette Sandholm Kastrup (Jette S Kastrup)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 21

Top Venues

The FEBS journal

ACS chemical neuroscience

Journal of medicinal chemistry

FEBS letters

University of Copenhagen

Royal Danish School of Pharmacy & Cheminova Agro A/S (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Copenhagen Oct 01 2016

Denmark

Professor :: Department of Drug Design and Pharmacology

The Faculty of Health and Medical Sciences, University of Copenhagen

Denmark

Professor (MSO) in structure-based drug design :: Department of Drug Design and Pharmacology

The Danish University of Pharmaceutical Sciences

Denmark

Associate professor :: Department of Medicinal Chemistry

Royal Danish School of Pharmacy

Denmark

Senior scientist :: Department of Medicinal Chemistry

Royal Danish School of Pharmacy

Denmark

Post doc :: Department of Medicinal Chemistry

Royal Danish School of Pharmacy

Denmark

Teaching assistant :: Deptartment of Organic Chemistry

Tårnby Apotek

Denmark

Periodic substitute

Education History

Royal Danish School of Pharmacy & Cheminova Agro A/S

Denmark

PHD

The Royal Danish School of Pharmacy

Denmark

MSC

Publications

Yasmin Bay, Mie Egeberg Jeppesen, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Darryl S Pickering, Anders Skov Kristensen, Jette Sandholm Kastrup
The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2. FEBS letters (2024)
Yasmin Bay, Mie Egeberg Jeppesen, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Darryl S Pickering, Anders Skov Kristensen, Jette Sandholm Kastrup
The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2. FEBS letters 598 (7) (2024)
Yasmin Bay, Raminta Venskutonytė, Stine M Frantsen, Thor S Thorsen, Maria Musgaard, Karla A Frydenvang, Pierre Francotte, Bernard Pirotte, Philip Charles Biggin, Anders S Kristensen, Thomas Boesen, Darryl S Pickering, Michael Gajhede, Jette Sandholm Kastrup
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The FEBS journal 291 (7) (2024)
Dilip Narayanan, Anne Sofie G Larsen, Stine Juul Gauger, Ruth Adafia, Rikke Bartschick Hammershøi, Louise Hamborg, Jesper Bruus-Jensen, Nane Griem-Krey, Christine L Gee, Bente Frølund, Margaret M Stratton, John Kuriyan, Jette Sandholm Kastrup, Annette Eva Langkilde, Petrine Wellendorph, Sara M Ø Solbak
Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity. Protein science : a publication of the Protein Society 33 (10) (2024)
Yasmin Bay, Mie Egeberg Jeppesen, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Darryl S Pickering, Anders Skov Kristensen, Jette Sandholm Kastrup
The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2. FEBS letters 598 (7) (2024)
Yasmin Bay, Raminta Venskutonytė, Stine M Frantsen, Thor S Thorsen, Maria Musgaard, Karla A Frydenvang, Pierre Francotte, Bernard Pirotte, Philip Charles Biggin, Anders S Kristensen, Thomas Boesen, Darryl S Pickering, Michael Gajhede, Jette Sandholm Kastrup
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The FEBS journal 291 (7) (2024)
Yasmin Bay, Raminta Venskutonytė, Stine M Frantsen, Thor S Thorsen, Maria Musgaard, Karla A Frydenvang, Pierre Francotte, Bernard Pirotte, Philip Charles Biggin, Anders S Kristensen, Thomas Boesen, Darryl S Pickering, Michael Gajhede, Jette Sandholm Kastrup
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The FEBS journal (2023)
Yasmin Bay, Raminta Venskutonytė, Stine M Frantsen, Thor S Thorsen, Maria Musgaard, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Philip C Biggin, Anders S Kristensen, Thomas Boesen, Darryl S Pickering, Michael Gajhede, Jette Sandholm Kastrup
Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure. The FEBS journal (2023)
Magdalena Masternak, Angela Koch, Saara Laulumaa, Daniel Tapken, Michael Hollmann, Flemming Steen Jørgensen, Jette Sandholm Kastrup
Differences between the GluD1 and GluD2 receptors revealed by GluD1 X-ray crystallography, binding studies and molecular dynamics. The FEBS journal (2022)
Koffi Sénam Etsè, Jerzy Dorosz, Katrine McLain Christensen, Jean-Yves Thomas, Iuliana Botez Pop, Eric Goffin, Thomas Colson, Pierre Lestage, Laurence Danober, Bernard Pirotte, Jette Sandholm Kastrup, Pierre Francotte
Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors. ACS chemical neuroscience 12 (14) (2021)
Karla A Frydenvang, Darryl S Pickering, Jette Sandholm Kastrup
Structural basis for positive allosteric modulation of AMPA and kainate receptors. The Journal of physiology (2021)
Karla A Frydenvang, Darryl S Pickering, Giridhar U Kshirsagar, Giulia Chemi, Sandra Gemma, Desiree Sprogøe, Anne Mette Kærn, Simone Brogi, Giuseppe Campiani, Stefania Butini, Jette Sandholm Kastrup
Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions. ACS chemical neuroscience 11 (12) (2020)
Christian Krintel, Jerzy Dorosz, Andreas Haahr Larsen, Thor Seneca Thorsen, Raminta Venskutonytė, Osman Asghar Mirza, Michael Gajhede, Thomas Boesen, Jette Sandholm Kastrup
Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. The FEBS journal 288 (3) (2020)
Jakob Pallesen, Stine Møllerud, Karla A Frydenvang, Darryl S Pickering, Jan Bornholdt, Birgitte Nielsen, Diletta Pasini, Liwei Han, Laura Marconi, Jette Sandholm Kastrup, Tommy N Johansen
N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology. ACS chemical neuroscience 10 (3) (2019)
Stine Møllerud, Rie B Hansen, Jakob Pallesen, Piero Temperini, Diletta Pasini, Jan Bornholt, Birgitte Nielsen, Esmira Mamedova, Paulina Chalupnik, Ana V Paternain, Juan Lerma, Marta Diaz-delCastillo, Jesper T Andreasen, Karla A Frydenvang, Jette Sandholm Kastrup, Tommy N Johansen, Darryl S Pickering
N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo Pharmacology. ACS chemical neuroscience 10 (11) (2019)
Stefano Sainas, Piero Temperini, Jill C Farnsworth, Feng Yi, Stine Møllerud, Anders A Jensen, Birgitte Nielsen, Alice Passoni, Jette Sandholm Kastrup, Kasper B Hansen, Donatella Boschi, Darryl S Pickering, Rasmus Prætorius Clausen, Marco Lucio Lolli
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. Journal of medicinal chemistry 62 (9) (2019)
Simone Brogi, Margherita Brindisi, Stefania Butini, Giridhar U Kshirsagar, Samuele Maramai, Giulia Chemi, Sandra Gemma, Giuseppe Campiani, Ettore Novellino, Paolo Fiorenzani, Jessica Pinassi, Anna Maria Aloisi, Mikko Gynther, Raminta Venskutonytė, Liwei Han, Karla Frydenvang, Jette Sandholm Kastrup, Darryl S Pickering
( S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation. Journal of medicinal chemistry 61 (5) (2018)
Thomas Drapier, Pierre Geubelle, Charlotte Bouckaert, Lise Nielsen, Saara Laulumaa, Eric Goffin, Sébastien Dilly, Pierre Francotte, Julien Hanson, Lionel Pochet, Jette Sandholm Kastrup, Bernard Pirotte
Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds. Journal of medicinal chemistry 61 (12) (2018)
Andreas Haahr Larsen, Jerzy Dorosz, Thor Seneca Thorsen, Nicolai Tidemand Johansen, Tamim A Darwish, Søren Roi Midtgaard, Lise Arleth, Jette Sandholm Kastrup
Small-angle neutron scattering studies on the AMPA receptor GluA2 in the resting, AMPA-bound and GYKI-53655-bound states. IUCrJ 5 (Pt 6) (2018)
Eric Goffin, Thomas Drapier, Anja Probst Larsen, Pierre Geubelle, Christopher P Ptak, Saara Laulumaa, Karoline Rovinskaja, Julie Gilissen, Pascal de Tullio, Lars Olsen, Karla Frydenvang, Bernard Pirotte, Julien Hanson, Robert E Oswald, Jette Sandholm Kastrup, Pierre Francotte
7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. Journal of medicinal chemistry 61 (1) (2017)
Stine Møllerud, Andrea Pinto, Laura Marconi, Karla Frydenvang, Thor Seneca Thorsen, Saara Laulumaa, Raminta Venskutonytė, Sebastian Winther, Ana Maria Cuñado Moral, Lucia Tamborini, Paola Conti, Darryl S Pickering, Jette Sandholm Kastrup
Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors. ACS chemical neuroscience 8 (9) (2017)

Jette Sandholm Kastrup.css-eqlu8i{font-size:small;padding-left:4px;} (Jette S Kastrup)

Publication Activity (10 Years)

Top Topics

Top Venues

Jette Sandholm Kastrup (Jette S Kastrup)