Donatella Boschi

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 22

Top Topics

Acute Myeloid Leukemia

Mass Spectrometry

Molecular Dynamics Simulations

Top Venues

Journal of medicinal chemistry

Acta crystallographica. Section D, Structural biology

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

J Stuart Grossert, Andrew M J Crowell, Donatella Boschi, Marco Lucio Lolli, Robert L White
Tandem mass spectrometry of homologous 3-hydroxyfurazan and nitrile amino acids: Analysis of cooperative interactions and fragmentation processes. Journal of mass spectrometry : JMS 59 (6) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology 80 (Pt 6) (2024)
Agnese C Pippione, Chiara Vigato, Cristina Tucciarello, Samrina Hussain, Edoardo Salladini, Ha H Truong, Niel M Henriksen, Gaia Vanzetti, Giorgia Giordano, Daniele Zonari, Osman Asghar Mirza, Karla A Frydenvang, Ymera Pignochino, Simonetta Oliaro-Bosso, Donatella Boschi, Marco Lucio Lolli
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications. ACS medicinal chemistry letters 15 (8) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology 80 (Pt 6) (2024)
Marta Alberti, Giulio Poli, Luca Broggini, Stefano Sainas, Menico Rizzi, Donatella Boschi, Davide M Ferraris, Elena Martino, Stefano Ricagno, Tiziano Tuccinardi, Marco Lucio Lolli, Riccardo Miggiano
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent. Acta crystallographica. Section D, Structural biology (2024)
Agnese C Pippione, Chiara Vigato, Cristina Tucciarello, Samrina Hussain, Edoardo Salladini, Ha H Truong, Niel M Henriksen, Gaia Vanzetti, Giorgia Giordano, Daniele Zonari, Osman Asghar Mirza, Karla A Frydenvang, Ymera Pignochino, Simonetta Oliaro-Bosso, Donatella Boschi, Marco Lucio Lolli
AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications. ACS medicinal chemistry letters 15 (8) (2024)
Elena Martino, Shruti Thakur, Arun Kumar, Ashok Kumar Yadav, Donatella Boschi, Deepak Kumar, Marco Lucio Lolli
Insight in Quinazoline-based HDAC Inhibitors as Anti-cancer Agents. Mini reviews in medicinal chemistry (2024)
Tomasz M Wróbel, Katyayani Sharma, Iole Mannella, Simonetta Oliaro-Bosso, Patrycja Nieckarz, Therina Du Toit, Clarissa Daniela Voegel, Maria Natalia Rojas Velazquez, Jibira Yakubu, Anna Matveeva, Søren Therkelsen, Flemming Steen Jørgensen, Amit V Pandey, Agnese C Pippione, Marco L Lolli, Donatella Boschi, Fredrik Björkling
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis. Biomolecules 13 (9) (2023)
Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Alice Passoni, Valentina Gaidano, Agnese C Pippione, Nicoletta Vitale, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Cristina Ramondetti, Alessia Lanno, Davide M Ferraris, Barbara Canepa, Barbara Buccinnà, Marco Piccinini, Menico Rizzi, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Riccardo Miggiano, Tiziano Tuccinardi, Marco Lucio Lolli
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety. Journal of medicinal chemistry 65 (19) (2022)
Giulia Sibille, Anna Luganini, Stefano Sainas, Donatella Boschi, Marco Lucio Lolli, Giorgio Gribaudo
The Novel h DHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis. Viruses 14 (10) (2022)
Salvatore Galati, Stefano Sainas, Marta Giorgis, Donatella Boschi, Marco L Lolli, Gabriella Ortore, Giulio Poli, Tiziano Tuccinardi
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study. Molecules (Basel, Switzerland) 27 (12) (2022)
Valentina Gaidano, Mohammad Houshmand, Nicoletta Vitale, Giovanna Carrà, Alessandro Morotti, Valerio Tenace, Stefania Rapelli, Stefano Sainas, Agnese Chiara Pippione, Marta Giorgis, Donatella Boschi, Marco Lucio Lolli, Daniela Cilloni, Alessandro Cignetti, Giuseppe Saglio, Paola Circosta
The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia. Cancers 13 (5) (2021)
Arianna Calistri, Anna Luganini, Barbara Mognetti, Elizabeth Elder, Giulia Sibille, Valeria Conciatori, Claudia Del Vecchio, Stefano Sainas, Donatella Boschi, Nuria Montserrat, Ali Mirazimi, Marco Lucio Lolli, Giorgio Gribaudo, Cristina Parolin
The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses. Microorganisms 9 (8) (2021)
Stefano Sainas, Marta Giorgis, Paola Circosta, Valentina Gaidano, Davide Bonanni, Agnese C Pippione, Renzo Bagnati, Alice Passoni, Yaqi Qiu, Carina Florina Cojocaru, Barbara Canepa, Alessandro Bona, Barbara Rolando, Mariia Mishina, Cristina Ramondetti, Barbara Buccinnà, Marco Piccinini, Mohammad Houshmand, Alessandro Cignetti, Enrico Giraudo, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety. Journal of medicinal chemistry 64 (9) (2021)
Elina Rubin, Agnese C Pippione, Matthew Boyko, Giacomo Einaudi, Stefano Sainas, Massimo Collino, Carlo Cifani, Marco L Lolli, Naim Abu Freha, Jacob Kaplanski, Donatella Boschi, Abed N Azab
A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats. Brain sciences 12 (1) (2021)
Ana R N Santos, Helen M Sheldrake, Ali I M Ibrahim, Chhanda Charan Danta, Davide Bonanni, Martina Daga, Simonetta Oliaro-Bosso, Donatella Boschi, Marco Lucio Lolli, Klaus Pors
Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo-keto reductase 1C3 target affinity. MedChemComm 10 (8) (2019)
Alessandro Giraudo, Jacob Krall, Francesco Bavo, Birgitte Nielsen, Kenneth Thermann Kongstad, Barbara Rolando, Rossella De Blasio, David E Gloriam, Rebekka Löffler, Louise Thiesen, Kasper Harpsøe, Karla A Frydenvang, Donatella Boschi, Petrine Wellendorph, Marco Lucio Lolli, Anders A Jensen, Bente Frølund
Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at γ-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters. Journal of medicinal chemistry 62 (12) (2019)
Stefano Sainas, Piero Temperini, Jill C Farnsworth, Feng Yi, Stine Møllerud, Anders A Jensen, Birgitte Nielsen, Alice Passoni, Jette Sandholm Kastrup, Kasper B Hansen, Donatella Boschi, Darryl S Pickering, Rasmus Prætorius Clausen, Marco Lucio Lolli
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. Journal of medicinal chemistry 62 (9) (2019)
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Valentina Gaidano, Parveen Goyal, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Alex Ducime, Mikael Andersson, Michael A Järvå, Rosmarie Friemann, Marco Piccinini, Cristina Ramondetti, Barbara Buccinnà, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli
Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors. Journal of medicinal chemistry 62 (3) (2019)
Stefano Sainas, Agnese C Pippione, Elisa Lupino, Marta Giorgis, Paola Circosta, Valentina Gaidano, Parveen Goyal, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Alex Ducime, Mikael Andersson, Michael A Järvå, Rosmarie Friemann, Marco Piccinini, Cristina Ramondetti, Barbara Buccinnà, Salam Al-Karadaghi, Donatella Boschi, Giuseppe Saglio, Marco Lucio Lolli
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors. Journal of medicinal chemistry 61 (14) (2018)
Agnese C Pippione, Stefano Sainas, Antonella Federico, Elisa Lupino, Marco Piccinini, Michael Kubbutat, Jean-Marie Contreras, Christophe Morice, Alessandro Barge, Alex Ducime, Donatella Boschi, Salam Al-Karadaghi, Marco Lucio Lolli
N-Acetyl-3-aminopyrazoles block the non-canonical NF-kB cascade by selectively inhibiting NIK. MedChemComm 9 (6) (2018)
Agnese C Pippione, Antonella Federico, Alex Ducime, Stefano Sainas, Donatella Boschi, Alessandro Barge, Elisa Lupino, Marco Piccinini, Michael Kubbutat, Jean-Marie Contreras, Christophe Morice, Salam Al-Karadaghi, Marco Lucio Lolli
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade. MedChemComm 8 (9) (2017)