David Bikard

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 34

Top Venues

Nature

Nucleic acids research

Science advances

Comptes rendus biologies

Institut Pasteur

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institut Pasteur

France

Head of Lab :: Microbiology

Publications

Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature 632 (8026) (2024)
Nathaniel Burman, Svetlana Belukhina, Florence Depardieu, Royce A Wilkinson, Mikhail Skutel, Andrew Santiago-Frangos, Ava B Graham, Alexei Livenskyi, Anna Chechenina, Natalia Morozova, Trevor Zahl, William S Henriques, Murat Buyukyoruk, Christophe Rouillon, Baptiste Saudemont, Elena Y Shyrokova, Tatsuaki Kurata, Vasili Hauryliuk, Konstantin Severinov, Justine Groseille, Agnès Thierry, Romain Koszul, Florian Tesson, Aude Bernheim, David Bikard, Blake Wiedenheft, Artem Isaev
A virally-encoded tRNA neutralizes the PARIS antiviral defence system. Nature (2024)
Nathaniel Burman, Svetlana Belukhina, Florence Depardieu, Royce A Wilkinson, Mikhail Skutel, Andrew Santiago-Frangos, Ava B Graham, Alexei Livenskyi, Anna Chechenina, Natalia Morozova, Trevor Zahl, William S Henriques, Murat Buyukyoruk, Christophe Rouillon, Baptiste Saudemont, Elena Y Shyrokova, Tatsuaki Kurata, Vasili Hauryliuk, Konstantin Severinov, Justine Groseille, Agnès Thierry, Romain Koszul, Florian Tesson, Aude Bernheim, David Bikard, Blake Wiedenheft, Artem Isaev
A virally-encoded tRNA neutralizes the PARIS antiviral defence system. Nature (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature 632 (8026) (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature 632 (8026) (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature 632 (8026) (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature (2024)
Egill Richard, Baptiste Darracq, Eloi Littner, Claire Vit, Clémence Whiteway, Julia Bos, Florian Fournes, Geneviève Garriss, Valentin Conte, Delphine Lapaillerie, Vincent Parissi, François Rousset, Ole Skovgaard, David Bikard, Eduardo P C Rocha, Didier Mazel, Céline Loot
Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems. Science advances 10 (2) (2024)
Andreas K Brödel, Loïc H Charpenay, Matthieu Galtier, Fabien J Fuche, Rémi Terrasse, Chloé Poquet, Jan Havránek, Simone Pignotti, Antonina Krawczyk, Marion Arraou, Gautier Prevot, Dalila Spadoni, Matthew T N Yarnall, Edith M Hessel, Jesus Fernandez-Rodriguez, Xavier Duportet, David Bikard
In situ targeted base editing of bacteria in the mouse gut. Nature (2024)
Egill Richard, Baptiste Darracq, Eloi Littner, Claire Vit, Clémence Whiteway, Julia Bos, Florian Fournes, Geneviève Garriss, Valentin Conte, Delphine Lapaillerie, Vincent Parissi, François Rousset, Ole Skovgaard, David Bikard, Eduardo P C Rocha, Didier Mazel, Céline Loot
Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems. Science advances 10 (2) (2024)
William Rostain, Theophile Grebert, Danylo Vyhovskyi, Paula Thiel Pizarro, Gatwa Tshinsele-Van Bellingen, Lun Cui, David Bikard
Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity. Nucleic acids research (2023)
Cyril Malbranke, William Rostain, Florence Depardieu, Simona Cocco, Rémi Monasson, David Bikard
Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment. PLoS computational biology 19 (11) (2023)
David Bikard
How has microbiology changed 200 years after Pasteur's birth? Comptes rendus biologies 345 (3) (2022)
Damien Piel, Maxime Bruto, Yannick Labreuche, François Blanquart, David Goudenège, Rubén Barcia-Cruz, Sabine Chenivesse, Sophie Le Panse, Adèle James, Javier Dubert, Bruno Petton, Erica Lieberman, K Mathias Wegner, Fatima A Hussain, Kathryn M Kauffman, Martin F Polz, David Bikard, Sylvain Gandon, Eduardo P C Rocha, Frédérique Le Roux
Phage-host coevolution in natural populations. Nature microbiology 7 (7) (2022)
Eduardo P C Rocha, David Bikard
Microbial defenses against mobile genetic elements and viruses: Who defends whom from what? PLoS biology 20 (1) (2022)
David Bikard
How has microbiology changed 200 years after Pasteur's birth? Comptes rendus biologies 345 (3) (2022)
Alex Hawkins-Hooker, Florence Depardieu, Sebastien Baur, Guillaume Couairon, Arthur Chen, David Bikard
Generating functional protein variants with variational autoencoders. PLoS computational biology 17 (2) (2021)
François Rousset, Jose Cabezas-Caballero, Florence Piastra-Facon, Jesús Fernández-Rodríguez, Olivier Clermont, Erick Denamur, Eduardo P C Rocha, David Bikard
The impact of genetic diversity on gene essentiality within the Escherichia coli species. Nature microbiology 6 (3) (2021)
David Ranava, Yiying Yang, Luis Orenday-Tapia, François Rousset, Catherine Turlan, Violette Morales, Lun Cui, Cyril Moulin, Carine Froment, Gladys Munoz, Jérôme Rech, Julien Marcoux, Anne Caumont-Sarcos, Cécile Albenne, David Bikard, Raffaele Ieva
Lipoprotein DolP supports proper folding of BamA in the bacterial outer membrane promoting fitness upon envelope stress. eLife 10 (2021)
Aleksandra Nivina, Maj Svea Grieb, Céline Loot, David Bikard, Jean Cury, Laila Shehata, Juliana Silva Bernardes, Didier Mazel
Structure-specific DNA recombination sites: Design, validation, and machine learning-based refinement. Science advances 6 (30) (2020)
Antoine Vigouroux, David Bikard
CRISPR Tools To Control Gene Expression in Bacteria. Microbiology and molecular biology reviews : MMBR 84 (2) (2020)
François Rousset, Lun Cui, Elise Siouve, Christophe Becavin, Florence Depardieu, David Bikard
Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors. PLoS genetics 14 (11) (2018)
Lun Cui, Antoine Vigouroux, François Rousset, Hugo Varet, Varun Khanna, David Bikard
A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9. Nature communications 9 (1) (2018)
Antoine Vigouroux, Enno R Oldewurtel, Lun Cui, David Bikard, Sven van Teeffelen
Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes. Molecular systems biology 14 (3) (2018)
Aude Bernheim, Alicia Calvo-Villamañán, Clovis Basier, Lun Cui, Eduardo P C Rocha, Marie Touchon, David Bikard
Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria. Nature communications 8 (1) (2017)
Julian R Garneau, Florence Depardieu, Louis-Charles Fortier, David Bikard, Marc Monot
PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data. Scientific reports 7 (1) (2017)
Lun Cui, David Bikard
Consequences of Cas9 cleavage in the chromosome of Escherichia coli. Nucleic acids research 44 (9) (2016)
David Bikard, Chad W Euler, Wenyan Jiang, Philip M Nussenzweig, Gregory W Goldberg, Xavier Duportet, Vincent A Fischetti, Luciano A Marraffini
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials. Nature biotechnology 32 (11) (2014)

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Publication Activity (10 Years)

Top Topics

Top Venues

David Bikard