Chase L Beisel (Chase Beisel, C L Beisel)

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 64

Top Topics

Mass Spectrometry

Dna Methylation

Klebsiella Pneumoniae

Top Venues

Nature communications

Nucleic acids research

This page only lists publications with an associated author ORCID identifier.

Publications

Nils Birkholz, Kotaro Kamata, Maximilian Feussner, Max E Wilkinson, Christian Cuba Samaniego, Angela Migur, Dari Kimanius, Marijn Ceelen, Sam C Went, Ben Usher, Tim R Blower, Warren P Tate, Chase L Beisel, Zasha Weinberg, Robert D Fagerlund, Simon A Jackson, Peter C Fineran
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature (2024)
Chunlei Jiao, Natalia L Peeck, Jiaqi Yu, Mohammad Ghaem Maghami, Sarah Kono, Daphne Collias, Sandra L Martinez Diaz, Rachael Larose, Chase L Beisel
TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases. Nature communications 15 (1) (2024)
Gianluca Prezza, Chunyu Liao, Sarah Reichardt, Chase L Beisel, Alexander J Westermann
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron . Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Gianluca Prezza, Chunyu Liao, Sarah Reichardt, Chase L Beisel, Alexander J Westermann
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron . Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Aset Khakimzhan, Ziane Izri, Seth Thompson, Oleg Dmytrenko, Patrick Fischer, Chase L Beisel, Vincent Noireaux
Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins. Communications biology 7 (1) (2024)
Nils Birkholz, Kotaro Kamata, Maximilian Feussner, Max E Wilkinson, Christian Cuba Samaniego, Angela Migur, Dari Kimanius, Marijn Ceelen, Sam C Went, Ben Usher, Tim R Blower, Warren P Tate, Chase L Beisel, Zasha Weinberg, Robert D Fagerlund, Simon A Jackson, Peter C Fineran
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature 631 (8021) (2024)
Sandra Gawlitt, Scott P Collins, Yanying Yu, Samuel A Blackman, Lars Barquist, Chase L Beisel
Expanding the flexibility of base editing for high-throughput genetic screens in bacteria. Nucleic acids research 52 (7) (2024)
Nicolas Krink, Pablo Iván Nikel, Chase L Beisel
A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist. EMBO reports 25 (4) (2024)
Sandra Gawlitt, Scott P Collins, Yanying Yu, Samuel A Blackman, Lars Barquist, Chase L Beisel
Expanding the flexibility of base editing for high-throughput genetic screens in bacteria. Nucleic acids research 52 (7) (2024)
Chunlei Jiao, Natalia L Peeck, Jiaqi Yu, Mohammad Ghaem Maghami, Sarah Kono, Daphne Collias, Sandra L Martinez Diaz, Rachael Larose, Chase L Beisel
TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases. Nature communications 15 (1) (2024)
Aset Khakimzhan, Ziane Izri, Seth Thompson, Oleg Dmytrenko, Patrick Fischer, Chase L Beisel, Vincent Noireaux
Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins. Communications biology 7 (1) (2024)
Nicolas Krink, Pablo Iván Nikel, Chase L Beisel
A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist. EMBO reports 25 (4) (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Nicolas Krink, Pablo Iván Nikel, Chase L Beisel
A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist. EMBO reports (2024)
Nils Birkholz, Kotaro Kamata, Maximilian Feussner, Max E Wilkinson, Christian Cuba Samaniego, Angela Migur, Dari Kimanius, Marijn Ceelen, Sam C Went, Ben Usher, Tim R Blower, Warren P Tate, Chase L Beisel, Zasha Weinberg, Robert D Fagerlund, Simon A Jackson, Peter C Fineran
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature 631 (8021) (2024)
Sandra Gawlitt, Scott P Collins, Yanying Yu, Samuel A Blackman, Lars Barquist, Chase L Beisel
Expanding the flexibility of base editing for high-throughput genetic screens in bacteria. Nucleic acids research (2024)
Nils Birkholz, Kotaro Kamata, Maximilian Feussner, Max E Wilkinson, Christian Cuba Samaniego, Angela Migur, Dari Kimanius, Marijn Ceelen, Sam C Went, Ben Usher, Tim R Blower, Warren P Tate, Chase L Beisel, Zasha Weinberg, Robert D Fagerlund, Simon A Jackson, Peter C Fineran
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature (2024)
Aset Khakimzhan, Ziane Izri, Seth Thompson, Oleg Dmytrenko, Patrick Fischer, Chase L Beisel, Vincent Noireaux
Cell-free expression with a quartz crystal microbalance enables rapid, dynamic, and label-free characterization of membrane-interacting proteins. Communications biology 7 (1) (2024)
Gianluca Prezza, Chunyu Liao, Sarah Reichardt, Chase L Beisel, Alexander J Westermann
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron . Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Elena Vialetto, Solange Miele, Moran G Goren, Jiaqi Yu, Yanying Yu, Daphne Collias, Beatriz Beamud, Lisa Osbelt, Marta Lourenço, Till Strowig, Sylvain Brisse, Lars Barquist, Qimron Udi, David Bikard, Chase L Beisel
Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity. Nucleic acids research 52 (10) (2024)
Chunlei Jiao, Natalia L Peeck, Jiaqi Yu, Mohammad Ghaem Maghami, Sarah Kono, Daphne Collias, Sandra L Martinez Diaz, Rachael Larose, Chase L Beisel
TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases. Nature communications 15 (1) (2024)
Nicolas Krink, Pablo Iván Nikel, Chase L Beisel
A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist. EMBO reports 25 (4) (2024)
Gianluca Prezza, Chunyu Liao, Sarah Reichardt, Chase L Beisel, Alexander J Westermann
CRISPR-based screening of small RNA modulators of bile susceptibility in Bacteroides thetaiotaomicron . Proceedings of the National Academy of Sciences of the United States of America 121 (6) (2024)
Nicolas Krink, Pablo Iván Nikel, Chase L Beisel
A Hitchhiker's guide to CRISPR editing tools in bacteria : CRISPR can help unlock the bacterial world, but technical and regulatory barriers persist. EMBO reports 25 (4) (2024)
Nils Birkholz, Kotaro Kamata, Maximilian Feussner, Max E Wilkinson, Christian Cuba Samaniego, Angela Migur, Dari Kimanius, Marijn Ceelen, Sam C Went, Ben Usher, Tim R Blower, Warren P Tate, Chase L Beisel, Zasha Weinberg, Robert D Fagerlund, Simon A Jackson, Peter C Fineran
Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature 631 (8021) (2024)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Daphne Collias, Elena Vialetto, Jiaqi Yu, Khoa Co, Éva D H Almási, Ann-Sophie Rüttiger, Tatjana Achmedov, Till Strowig, Chase L Beisel
Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria. Nature communications 14 (1) (2023)
Daphne Collias, Elena Vialetto, Jiaqi Yu, Khoa Co, Éva D H Almási, Ann-Sophie Rüttiger, Tatjana Achmedov, Till Strowig, Chase L Beisel
Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria. Nature communications 14 (1) (2023)
Daphne Collias, Elena Vialetto, Jiaqi Yu, Khoa Co, Éva D H Almási, Ann-Sophie Rüttiger, Tatjana Achmedov, Till Strowig, Chase L Beisel
Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria. Nature communications 14 (1) (2023)
Sarah P Esser, Janina Rahlff, Weishu Zhao, Michael Predl, Julia Plewka, Katharina Sures, Franziska Wimmer, Janey Lee, Panagiotis S Adam, Julia McGonigle, Victoria Turzynski, Indra Banas, Katrin Schwank, Mart Krupovic, Till L V Bornemann, Perla Abigail Figueroa-Gonzalez, Jessica K Jarett, Thomas Rattei, Yuki Amano, Ian K Blaby, Jan-Fang Cheng, William J Brazelton, Chase L Beisel, Tanja Woyke, Ying Zhang, Alexander J Probst
A predicted CRISPR-mediated symbiosis between uncultivated archaea. Nature microbiology (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Chunlei Jiao, Claas Reckstadt, Fabian König, Christina Homberger, Jiaqi Yu, Jörg Vogel, Alexander J Westermann, Cynthia Mira Sharma, Chase L Beisel
RNA recording in single bacterial cells using reprogrammed tracrRNAs. Nature biotechnology (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Chunlei Jiao, Claas Reckstadt, Fabian König, Christina Homberger, Jiaqi Yu, Jörg Vogel, Alexander J Westermann, Cynthia Mira Sharma, Chase L Beisel
RNA recording in single bacterial cells using reprogrammed tracrRNAs. Nature biotechnology (2023)
Franziska Wimmer, Frank Englert, Katharina G Wandera, Omer S Alkhnbashi, Scott P Collins, Rolf Backofen, Chase L Beisel
Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation. Nucleic acids research (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Sandra Gawlitt, Chunyu Liao, Tatjana Achmedov, Chase L Beisel
Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint. RNA biology 20 (1) (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Daphne Collias, Elena Vialetto, Jiaqi Yu, Khoa Co, Éva D H Almási, Ann-Sophie Rüttiger, Tatjana Achmedov, Till Strowig, Chase L Beisel
Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria. Nature communications 14 (1) (2023)
Jack P K Bravo, Thomson Hallmark, Bronson Naegle, Chase L Beisel, Ryan N Jackson, David W Taylor
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2. Nature 613 (7944) (2023)
Oleg Dmytrenko, Gina C Neumann, Thomson Hallmark, Dylan J Keiser, Valerie M Crowley, Elena Vialetto, Ioannis Mougiakos, Katharina G Wandera, Hannah Domgaard, Johannes Weber, Thomas Gaudin, Josie Metcalf, Benjamin N Gray, Matthew B Begemann, Ryan N Jackson, Chase L Beisel
Cas12a2 elicits abortive infection through RNA-triggered destruction of dsDNA. Nature 613 (7944) (2023)
Chunyu Liao, Sahil Sharma, Sarah L Svensson, Anuja Kibe, Zasha Weinberg, Omer S Alkhnbashi, Thorsten Bischler, Rolf Backofen, Neva Caliskan, Cynthia Mira Sharma, Chase L Beisel
Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA. Nature microbiology 7 (4) (2022)
Anke Sparmann, Chase L Beisel
CRISPR memories in single cells. Molecular systems biology 18 (4) (2022)
Daphne Collias, Chase L Beisel
CRISPR technologies and the search for the PAM-free nuclease. Nature communications 12 (1) (2021)
Chrysanthi Taxiarchi, Andrea Beaghton, Nayomi Illansinhage Don, Kyros Kyrou, Matthew Gribble, Dammy Shittu, Scott P Collins, Chase L Beisel, Roberto Galizi, Andrea Crisanti
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression. Nature communications 12 (1) (2021)
Chunlei Jiao, Sahil Sharma, Gaurav Dugar, Natalia L Peeck, Thorsten Bischler, Franziska Wimmer, Yanying Yu, Lars Barquist, Christoph Schoen, Oliver Kurzai, Cynthia Mira Sharma, Chase L Beisel
Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9. Science (New York, N.Y.) 372 (6545) (2021)
Daphne Collias, R T Leenay, Rebecca A Slotkowski, Z Zuo, S P Collins, B A McGirr, Jin Liu, Chase L Beisel
A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9. Science advances 6 (29) (2020)
Adrian Pickar-Oliver, Joshua B Black, Mae M Lewis, Kevin J Mutchnick, Tyler S Klann, Kylie A Gilcrest, Madeleine J Sitton, Christopher E Nelson, Alejandro Barrera, Luke C Bartelt, Timothy E Reddy, Chase L Beisel, Rodolphe Barrangou, Charles A Gersbach
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. Nature biotechnology 37 (12) (2019)
Chunyu Liao, Fani Ttofali, Rebecca A Slotkowski, Steven R Denny, Taylor D Cecil, Ryan T Leenay, Albert J Keung, Chase L Beisel
Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis. Nature communications 10 (1) (2019)
Justin M Vento, Nathan C Crook, Chase L Beisel
Barriers to genome editing with CRISPR in bacteria. Journal of industrial microbiology & biotechnology 46 (9-10) (2019)
Alexandra Westbrook, Xun Tang, Ryan Marshall, Colin S Maxwell, James Chappell, Deepak K Agrawal, Mary J Dunlop, Vincent Noireaux, Chase L Beisel, Julius B Lucks, Elisa Franco
Distinct timescales of RNA regulators enable the construction of a genetic pulse generator. Biotechnology and bioengineering 116 (5) (2019)
David Garenne, Chase L Beisel, Vincent Noireaux
Characterization of the all-E. coli transcription-translation system myTXTL by mass spectrometry. Rapid communications in mass spectrometry : RCM 33 (11) (2019)
Chunyu Liao, Rebecca A Slotkowski, Tatjana Achmedov, Chase L Beisel
The Francisella novicida Cas12a is sensitive to the structure downstream of the terminal repeat in CRISPR arrays. RNA biology 16 (4) (2018)