David Dt Thomas (David D Thomas)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 43

Top Venues

eLife

bioRxiv : the preprint server for biology

Nature communications

Biomolecules

University of Minnesota Twin Cities

Stanford University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Minnesota Twin Cities

United States

Professor :: Biophysics, Molecular Biology and Biophysics

Education History

Stanford University

United States

PHD :: Biophysics (H. McConnell)

Stanford University

United States

BSC :: Physics

Publications

Robyn T Rebbeck, Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David Dt Thomas, Donald M Bers, Razvan L Cornea
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors. Nature communications 15 (1) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Robyn T Rebbeck, Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David Dt Thomas, Donald M Bers, Razvan L Cornea
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors. Nature communications 15 (1) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Robyn T Rebbeck, Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David Dt Thomas, Donald M Bers, Razvan L Cornea
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors. Nature communications 15 (1) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Robyn T Rebbeck, Bengt Svensson, Jingyan Zhang, Montserrat Samsó, David Dt Thomas, Donald M Bers, Razvan L Cornea
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors. Nature communications 15 (1) (2024)
Osha Roopnarine, David Dt Thomas
Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy. Applied magnetic resonance 55 (1-3) (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Bengt Svensson, Florentin R Nitu, Robyn T Rebbeck, Lindsey M McGurran, Tetsuro Oda, David Dt Thomas, Donald M Bers, Razvan L Cornea
Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State. bioRxiv : the preprint server for biology (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Jaroslava Šeflová, Jacob A Schwarz, Abigail N Smith, Bengt Svensson, Daniel J Blackwell, Taylor A Phillips, Roman Nikolaienko, Elisa Bovo, Robyn T Rebbeck, Aleksey V Zima, David Dt Thomas, Filip Van Petegem, Björn C Knollmann, Jeffrey N Johnston, Seth L Robia, Razvan L Cornea
RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. ACS chemical biology (2023)
Osha Roopnarine, David Dt Thomas
Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy. Applied magnetic resonance 55 (1-3) (2023)
Bengt Svensson, Florentin R Nitu, Robyn T Rebbeck, Lindsey M McGurran, Tetsuro Oda, David Dt Thomas, Donald M Bers, Razvan L Cornea
Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State. International journal of molecular sciences 24 (16) (2023)
Osha Roopnarine, Samantha L Yuen, Andrew R Thompson, Lauren N Roelike, Robyn T Rebbeck, Philip A Bidwell, Courtney C Aldrich, Razvan L Cornea, David Dt Thomas
FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators. bioRxiv : the preprint server for biology (2023)
Thomas A Bunch, Piyali Guhathakurta, Andrew R Thompson, Victoria C Lepak, Anna L Carter, Jennifer J Thomas, David Dt Thomas, Brett A Colson
Drug discovery for heart failure targeting myosin-binding protein C. bioRxiv : the preprint server for biology (2023)
Osha Roopnarine, David Dt Thomas
Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy. Applied magnetic resonance 55 (1-3) (2023)
Philip A Bidwell, Samantha L Yuen, Ji Li, Kaja Berg, Robyn T Rebbeck, Courtney C Aldrich, Osha Roopnarine, Razvan L Cornea, David Dt Thomas
A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules 12 (12) (2022)
Philip A Bidwell, Samantha L Yuen, Ji Li, Kaja Berg, Robyn T Rebbeck, Courtney C Aldrich, Osha Roopnarine, Razvan L Cornea, David Dt Thomas
A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules 12 (12) (2022)
Philip A Bidwell, Samantha L Yuen, Ji Li, Kaja Berg, Robyn T Rebbeck, Courtney C Aldrich, Osha Roopnarine, Razvan L Cornea, David Dt Thomas
A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules 12 (12) (2022)
Matthew Simon, Jiping Yang, Jonathan Gigas, Eric Jay Earley, Eric Hillpot, Lei Zhang, Maria Zagorulya, Greg Tombline, Michael Gilbert, Samantha L Yuen, Alexis Pope, Michael Van Meter, Stephan Emmrich, Denis Firsanov, Advait Athreya, Seyed Ali Biashad, Jeehae Han, Seungjin Ryu, Archana Tare, Yizhou Zhu, Adam D Hudgins, Gil Atzmon, Nir Barzilai, Aaron J Wolfe, Kelsey Moody, Benjamin A Garcia, David Dt Thomas, Paul D Robbins, Jan Vijg, Andrei Seluanov, Yousin Suh, Vera Gorbunova
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A. The EMBO journal 41 (21) (2022)
Philip A Bidwell, Samantha L Yuen, Ji Li, Kaja Berg, Robyn T Rebbeck, Courtney C Aldrich, Osha Roopnarine, Razvan L Cornea, David Dt Thomas
A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules 12 (12) (2022)
Philip A Bidwell, Samantha L Yuen, Ji Li, Kaja Berg, Robyn T Rebbeck, Courtney C Aldrich, Osha Roopnarine, Razvan L Cornea, David Dt Thomas
A Large-Scale High-Throughput Screen for Modulators of SERCA Activity. Biomolecules 12 (12) (2022)
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V S Manu, Fernando Porcelli, Donald K Blumenthal, David Dt Thomas, David A Bernlohr, Sanford M Simon, Susan S Taylor, Gianluigi Veglia
Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A. Communications biology 4 (1) (2021)
Daniel K Weber, U Venkateswara Reddy, Songlin Wang, Erik K Larsen, Tata Gopinath, Martin B Gustavsson, Razvan L Cornea, David Dt Thomas, Alfonso De Simone, Gianluigi Veglia
Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation. eLife 10 (2021)
Adak Karamafrooz, Jack Brennan, David Dt Thomas, Laurie L Parker
Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A (PRKACA) and Its Oncogenic Mutant DNAJB1-PRKACA. Journal of proteome research 20 (10) (2021)
Joseph M Autry, Bengt Svensson, Samuel F Carlson, Zhenhui Chen, Razvan L Cornea, David Dt Thomas, Stephanie J Valberg
Sarcoplasmic Reticulum from Horse Gluteal Muscle Is Poised for Enhanced Calcium Transport. Veterinary sciences 8 (12) (2021)
Abir Majumdar, David J Burban, Joseph M Muretta, Andrew R Thompson, Tiffany A Engel, Damien M Rasmussen, Manu V Subrahmanian, Gianluigi Veglia, David Dt Thomas, Nicholas M Levinson
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors. Nature chemical biology 17 (4) (2021)
Cristina Olivieri, Caitlin Walker, Adak Karamafrooz, Yingjie Wang, V S Manu, Fernando Porcelli, Donald K Blumenthal, David Dt Thomas, David A Bernlohr, Sanford M Simon, Susan S Taylor, Gianluigi Veglia
Author Correction: Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A. Communications biology 4 (1) (2021)
Robyn T Rebbeck, Daniel P Singh, Kevyn A Janicek, Donald M Bers, David Dt Thomas, Bradley S Launikonis, Razvan L Cornea
RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. Scientific reports 10 (1) (2020)
Piyali Guhathakurta, Lien A Phung, Ewa Prochniewicz, Sarah Lichtenberger, Anna Wilson, David Dt Thomas
Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac muscle. The Journal of biological chemistry 295 (41) (2020)
Cristina Olivieri, Yingjie Wang, Geoffrey C Li, Manu V S, Jonggul Kim, Benjamin R Stultz, Matthew Neibergall, Fernando Porcelli, Joseph M Muretta, David Dt Thomas, Jiali Gao, Donald K Blumenthal, Susan S Taylor, Gianluigi Veglia
Multi-state recognition pathway of the intrinsically disordered protein kinase inhibitor by protein kinase A. eLife 9 (2020)
Joseph M Autry, Christine B Karim, Sudeep Perumbakkam, Carrie J Finno, Erica C McKenzie, David Dt Thomas, Stephanie J Valberg
Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle. Veterinary sciences 7 (4) (2020)
Tory M Schaaf, Evan Kleinboehl, Samantha L Yuen, Lauren N Roelike, Bengt Svensson, Andrew R Thompson, Razvan L Cornea, David Dt Thomas
Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules that Enhance Ca2+ Transport. Cells 9 (5) (2020)
Lien A Phung, Aurora D Foster, Mark S Miller, Dawn A Lowe, David Dt Thomas
Super-relaxed state of myosin in human skeletal muscle is fiber-type dependent. American journal of physiology. Cell physiology 319 (6) (2020)
Yahor Savich, Benjamin P Binder, Andrew R Thompson, David Dt Thomas
Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels. The Journal of general physiology 151 (8) (2019)
Piyali Guhathakurta, Ewa Prochniewicz, David Dt Thomas
Actin-Myosin Interaction: Structure, Function and Drug Discovery. International journal of molecular sciences 19 (9) (2018)
Tory M Schaaf, Ang Li, Benjamin D Grant, Kurt Peterson, Samantha Yuen, Prachi Bawaskar, Evan Kleinboehl, Ji Li, David Dt Thomas, Gregory D Gillispie
Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening. Biosensors 8 (4) (2018)
Adam W Avery, Michael E Fealey, Fengbin Wang, Albina Orlova, Andrew R Thompson, David Dt Thomas, Thomas S Hays, Edward H Egelman
Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation. Nature communications 8 (1) (2017)

David Dt Thomas.css-eqlu8i{font-size:small;padding-left:4px;} (David D Thomas)

Publication Activity (10 Years)

Top Topics

Top Venues

David Dt Thomas (David D Thomas)