David E James

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 49

Top Venues

eLife

Nature communications

The Journal of experimental medicine

International journal of obesity (2005)

University of Sydney

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Sydney

Australia

Professor :: School of Life and Environmental Sciences

Publications

Julian van Gerwen, Stewart W C Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
The genetic and dietary landscape of the muscle insulin signalling network. eLife 12 (2024)
Senthil Thillainadesan, Aaron Lambert, Kristen C Cooke, Jacqueline Stöckli, Belinda Yau, Stewart W C Masson, Anna Howell, Meg Potter, Oliver K Fuller, Yi Lin Jiang, Melkam A Kebede, Grant Morahan, David E James, Søren Madsen, Samantha L Hocking
The metabolic consequences of 'yo-yo' dieting are markedly influenced by genetic diversity. International journal of obesity (2005) 48 (8) (2024)
Stewart W C Masson, Harry B Cutler, David E James
Unlocking metabolic insights with mouse genetic diversity. The EMBO journal (2024)
Julian van Gerwen, Stewart W C Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
The genetic and dietary landscape of the muscle insulin signalling network. eLife 12 (2024)
Senthil Thillainadesan, Aaron Lambert, Kristen C Cooke, Jacqueline Stöckli, Belinda Yau, Stewart W C Masson, Anna Howell, Meg Potter, Oliver K Fuller, Yi Lin Jiang, Melkam A Kebede, Grant Morahan, David E James, Søren Madsen, Samantha L Hocking
The metabolic consequences of 'yo-yo' dieting are markedly influenced by genetic diversity. International journal of obesity (2005) 48 (8) (2024)
Julian van Gerwen, Stewart W C Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
The genetic and dietary landscape of the muscle insulin signalling network. eLife 12 (2024)
Senthil Thillainadesan, Aaron Lambert, Kristen C Cooke, Jacqueline Stöckli, Belinda Yau, Stewart W C Masson, Anna Howell, Meg Potter, Oliver K Fuller, Yi Lin Jiang, Melkam A Kebede, Grant Morahan, David E James, Søren Madsen, Samantha L Hocking
The metabolic consequences of 'yo-yo' dieting are markedly influenced by genetic diversity. International journal of obesity (2005) (2024)
Julian van Gerwen, Stewart W C Masson, Harry B Cutler, Alexis Diaz Vegas, Meg Potter, Jacqueline Stöckli, Søren Madsen, Marin E Nelson, Sean J Humphrey, David E James
The genetic and dietary landscape of the muscle insulin signalling network. eLife 12 (2024)
Senthil Thillainadesan, Aaron Lambert, Kristen C Cooke, Jacqueline Stöckli, Belinda Yau, Stewart W C Masson, Anna Howell, Meg Potter, Oliver K Fuller, Yi Lin Jiang, Melkam A Kebede, Grant Morahan, David E James, Søren Madsen, Samantha L Hocking
The metabolic consequences of 'yo-yo' dieting are markedly influenced by genetic diversity. International journal of obesity (2005) 48 (8) (2024)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Karthickeyan Chella Krishnan, Elie-Julien El Hachem, Mark Keller, Sanjeet G Patel, Luke Carroll, Alexis Diaz Vegas, Isabela Gerdes Gyuricza, Christine Light, Yang Cao, Calvin Pan, Karolina Elżbieta Kaczor-Urbanowicz, Varun Shravah, Diana Anum, Matteo Pellegrini, Chi Fung Lee, Marcus M Seldin, Nadia A Rosenthal, Gary A Churchill, Alan Attie, Benjamin Parker, David E James, Aldons J Lusis
Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy. eLife 12 (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S Abraham, Nipunie S Rajapakse, Eric W Klee, Joseph A Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R Croucher, David E James, Cindy S Ma, Robert Brink, Stuart G Tangye, Elissa K Deenick
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. The Journal of experimental medicine 220 (6) (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Stewart W C Masson, Søren Madsen, Kristen C Cooke, Meg Potter, Alexis Diaz Vegas, Luke Carroll, Senthil Thillainadesan, Harry B Cutler, Ken R Walder, Gregory J Cooney, Grant Morahan, Jacqueline Stöckli, David E James
Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance. eLife 12 (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S Abraham, Nipunie S Rajapakse, Eric W Klee, Joseph A Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R Croucher, David E James, Cindy S Ma, Robert Brink, Stuart G Tangye, Elissa K Deenick
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. The Journal of experimental medicine 220 (6) (2023)
Alexis Diaz-Vegas, Soren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Ying Lim, Miro A Astore, Jonathan Morris, Anthony Simon Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. bioRxiv : the preprint server for biology (2023)
Hooman Allayee, Charles R Farber, Marcus M Seldin, Evan Graehl Williams, David E James, Aldons J Lusis
Systems genetics approaches for understanding complex traits with relevance for human disease. eLife 12 (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S Abraham, Nipunie S Rajapakse, Eric W Klee, Joseph A Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R Croucher, David E James, Cindy S Ma, Robert Brink, Stuart G Tangye, Elissa K Deenick
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. The Journal of experimental medicine 220 (6) (2023)
Tina Nguyen, Anthony Lau, Julia Bier, Kristen C Cooke, Helen Lenthall, Stephanie Ruiz-Diaz, Danielle T Avery, Henry Brigden, David Zahra, William A Sewell, Luke Droney, Satoshi Okada, Takaki Asano, Hassan Abolhassani, Zahra Chavoshzadeh, Roshini S Abraham, Nipunie S Rajapakse, Eric W Klee, Joseph A Church, Andrew Williams, Melanie Wong, Christoph Burkhart, Gulbu Uzel, David R Croucher, David E James, Cindy S Ma, Robert Brink, Stuart G Tangye, Elissa K Deenick
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. The Journal of experimental medicine 220 (6) (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Alexis Díaz-Vegas, Søren Madsen, Kristen C Cooke, Luke Carroll, Jasmine X Y Khor, Nigel Turner, Xin Y Lim, Miro A Astore, Jonathan C Morris, Anthony S Don, Amanda Garfield, Simona Zarini, Karin A Zemski Berry, Andrew P Ryan, Bryan C Bergman, Joseph T Brozinick, David E James, James G Burchfield
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle. eLife 12 (2023)
Daniel J Fazakerley, Julian van Gerwen, Kristen C Cooke, Xiaowen Duan, Elise J Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M Norris, Amber S Shun-Shion, James R Krycer, James G Burchfield, Pengyi Yang, Mark R Wade, Joseph T Brozinick, David E James, Sean J Humphrey
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance. Nature communications 14 (1) (2023)
Yuyuan Zheng, Lei Ding, Xianhui Meng, Meg Potter, Alison L Kearney, Jie Zhang, Jie Sun, David E James, Guang Yang, Chun Zhou
Structural insights into Ras regulation by SIN1. Proceedings of the National Academy of Sciences of the United States of America 119 (19) (2022)
Jeffrey Molendijk, Ronnie Blazev, Richard J Mills, Yaan-Kit Ng, Kevin I Watt, Daryn Chau, Paul Gregorevic, Peter J Crouch, James B W Hilton, Leszek Lisowski, Peixiang Zhang, Karen Reue, Aldons J Lusis, James Hudson, David E James, Marcus M Seldin, Benjamin L Parker
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function. eLife 11 (2022)
Alexis Díaz-Vegas, Dougall M Norris, Sigrid Jall-Rogg, Kristen C Cooke, Olivia J Conway, Amber S Shun-Shion, Xiaowen Duan, Meg Potter, Julian van Gerwen, Harry Jm Baird, Sean J Humphrey, David E James, Daniel J Fazakerley, James G Burchfield
A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology. Life science alliance 6 (1) (2022)
David E James, Jacqueline Stöckli, Morris J Birnbaum
The aetiology and molecular landscape of insulin resistance. Nature reviews. Molecular cell biology 22 (11) (2021)
Ariadna Recasens, Sean J Humphrey, Michael Ellis, Monira Hoque, Ramzi H Abbassi, Brianna Chen, Mitchell Longworth, Elise J Needham, David E James, Terrance G Johns, Bryan W Day, Michael Kassiou, Pengyi Yang, Lenka Munoz
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells. Cell death discovery 7 (1) (2021)
Taiyun Kim, Owen Tang, Stephen T Vernon, Katharine A Kott, Yen Chin Koay, John Park, David E James, Stuart M Grieve, Terence P Speed, Pengyi Yang, Gemma A Figtree, John F O'Sullivan, Jean Yee Hwa Yang
A hierarchical approach to removal of unwanted variation for large-scale metabolomics data. Nature communications 12 (1) (2021)
Milad Ghomlaghi, Guang Yang, Sung-Young Shin, David E James, Lan K Nguyen
Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1. PLoS computational biology 17 (9) (2021)
Elise J Needham, Janne R Hingst, Benjamin L Parker, Kaitlin R Morrison, Guang Yang, Johan Onslev, Jonas M Kristensen, Kurt Højlund, Naomi X Y Ling, Jonathan S Oakhill, Erik Arne Richter, Bente Kiens, Janni Petersen, Christian Pehmøller, David E James, Jørgen F P Wojtaszewski, Sean J Humphrey
Personalized phosphoproteomics identifies functional signaling. Nature biotechnology (2021)
Guang Yang, Deanne Francis, James R Krycer, Mark Larance, Ziyang Zhang, Kevan M Shokat, Alexis Díaz-Vegas, Kevan M Shokat, David E James
Dissecting the biology of mTORC1 beyond rapamycin. Science signaling 14 (701) (2021)
Alison L Kearney, Dougall M Norris, Milad Ghomlaghi, Martin Kin Lok Wong, Sean J Humphrey, Luke Carroll, Guang Yang, Kristen C Cooke, Pengyi Yang, Thomas A Geddes, Sungyoung Shin, Daniel J Fazakerley, Lan K Nguyen, David E James, James G Burchfield
Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis. eLife 10 (2021)
Amira Klip, Timothy E McGraw, David E James
Thirty sweet years of GLUT4. The Journal of biological chemistry 294 (30) (2019)
Alison L Kearney, Kristen C Cooke, Dougall M Norris, Armella Zadoorian, James R Krycer, Daniel J Fazakerley, James G Burchfield, David E James
Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes. The Journal of biological chemistry 294 (45) (2019)
Marin E Nelson, Benjamin L Parker, James G Burchfield, Nolan J Hoffman, Elise J Needham, Kristen C Cooke, Timur Naim, Lykke Sylow, Naomi Xy Ling, Deanne Francis, Dougall M Norris, Rima Chaudhuri, Jonathan S Oakhill, Erik Arne Richter, Gordon S Lynch, Jacqueline Stöckli, David E James
Phosphoproteomics reveals conserved exercise-stimulated signaling and AMPK regulation of store-operated calcium entry. The EMBO journal 38 (24) (2019)
Daniel J Fazakerley, Rima Chaudhuri, Pengyi Yang, Ghassan J Maghzal, Kristen C Thomas, James R Krycer, Sean J Humphrey, Benjamin L Parker, Kelsey H Fisher-Wellman, Christopher C Meoli, Nolan J Hoffman, Ciana Diskin, James G Burchfield, Mark J Cowley, Warren Kaplan, Zora Modrusan, Ganesh Kolumam, Jean Yh Yang, Daniel L Chen, Dorit Samocha-Bonet, Jerry R Greenfield, Kyle L Hoehn, Roland Stocker, David E James
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance. eLife 7 (2018)
Guang Yang, Sean J Humphrey, Danielle S Murashige, Deanne Francis, Qiao-Ping Wang, Kristen C Cooke, G Gregory Neely, David E James
RagC phosphorylation autoregulates mTOR complex 1. The EMBO journal 38 (3) (2018)
Richard J Mills, Drew M Titmarsh, Xaver Koenig, Benjamin L Parker, James G Ryall, Gregory A Quaife-Ryan, Holly K Voges, Mark P Hodson, Charles Ferguson, Lauren Drowley, Alleyn T Plowright, Elise J Needham, Qing-Dong Wang, Paul Gregorevic, Mei Xin, Walter G Thomas, Robert G Parton, Lars K Nielsen, Bradley S Launikonis, David E James, David A Elliott, Enzo R Porrello, James Edward Hudson
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America 114 (40) (2017)
Dougall M Norris, Pengyi Yang, James R Krycer, Daniel J Fazakerley, David E James, James G Burchfield
An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction. Journal of cell science 130 (16) (2017)
Zhipeng Li, Ryan J Schulze, Shaun G Weller, Eugene W Krueger, Micah B Schott, Xiaodong Zhang, Carol A Casey, Jun Liu, Jacqueline Stöckli, David E James, Mark A McNiven
A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets. Science advances 2 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

David E James