Ziyang Zhang

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 17

Top Venues

Nature chemical biology

Science (New York, N.Y.)

Science signaling

Nature

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

Harvard University Sep 01 2011

United States

PHD :: Chemistry

Peking University Sep 01 2007 - Jul 01 2011

China

BSC :: Chemistry

Publications

Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology (2024)
Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Qinheng Zheng, Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D. Nature chemical biology 20 (9) (2024)
Ziyang Zhang, Qiwen Fan, Xujun Luo, Kevin Lou, William A Weiss, Kevan M Shokat
Brain-restricted mTOR inhibition with binary pharmacology. Nature 609 (7928) (2022)
Ziyang Zhang, Keelan Z Guiley, Kevan M Shokat
Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S). Nature chemical biology 18 (11) (2022)
Ziyang Zhang, Johannes Morstein, Andrew K Ecker, Keelan Z Guiley, Kevan M Shokat
Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile. Journal of the American Chemical Society 144 (35) (2022)
Ziyang Zhang
Hacking the Permeability Barrier of Gram-Negative Bacteria. ACS central science 8 (8) (2022)
James D Vasta, D Matthew Peacock, Qinheng Zheng, Joel A Walker, Ziyang Zhang, Chad A Zimprich, Morgan R Thomas, Michael T Beck, Brock F Binkowski, Cesear R Corona, Matthew B Robers, Kevan M Shokat
KRAS is vulnerable to reversible switch-II pocket engagement in cells. Nature chemical biology 18 (6) (2022)
Kevin Lou, Douglas R Wassarman, Tangpo Yang, YiTing Paung, Ziyang Zhang, Thomas A O'Loughlin, Megan K Moore, Regina K Egan, Patricia Greninger, Cyril H Benes, Markus A Seeliger, Jack Taunton, Luke A Gilbert, Kevan M Shokat
IFITM proteins assist cellular uptake of diverse linked chemotypes. Science (New York, N.Y.) 378 (6624) (2022)
Yann Ehinger, Ziyang Zhang, Khanhky Phamluong, Drishti Soneja, Kevan M Shokat, Dorit Ron
Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 blockade in the periphery and reduces alcohol intake in mice. Nature communications 12 (1) (2021)
Tia A Tummino, Veronica V Rezelj, Benoit Fischer, Audrey Fischer, Matthew J O'Meara, Blandine Monel, Thomas Vallet, Kris M White, Ziyang Zhang, Assaf Alon, Heiko Schadt, Henry R Oâ Donnell, Jiankun Lyu, Romel Rosales, Briana L McGovern, Raveen Rathnasinghe, Sonia Jangra, Michael Schotsaert, Jean-René Galarneau, Nevan J Krogan, Laszlo Urban, Kevan M Shokat, Andrew C Kruse, Adolfo García-Sastre, Olivier Schwartz, Francesca Moretti, Marco Vignuzzi, Francois Pognan, Brian K Shoichet
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2. Science (New York, N.Y.) 373 (6554) (2021)
Guang Yang, Deanne Francis, James R Krycer, Mark Larance, Ziyang Zhang, Kevan M Shokat, Alexis Díaz-Vegas, Kevan M Shokat, David E James
Dissecting the biology of mTORC1 beyond rapamycin. Science signaling 14 (701) (2021)
David E Gordon, Gwendolyn M Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M White, Matthew J O'Meara, Veronica V Rezelj, Jeffrey Z Guo, Danielle L Swaney, Tia A Tummino, Ruth Hüttenhain, Robyn M Kaake, Alicia L Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J Polacco, Hannes Braberg, Jacqueline M Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J Bennett, Merve Cakir, Michael J McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T Kirby, James E Melnyk, John S Chorba, Kevin Lou, Shizhong A Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J P Mathy, Tina Perica, Kala Bharath Pilla, Sai J Ganesan, Daniel J Saltzberg, Ramachandran Rakesh, Xi Liu, Sara Brin Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, José M Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A Wankowicz, Markus Bohn, Maliheh Safari, Fatima S Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C O'Neal, Yiming Cai, Jason C J Chang, David J Broadhurst, Saker Klippsten, Phillip P Sharp, Nicole A Wenzell, Duygu Kuzuoglu-Ozturk, Hao-Yuan Wang, Raphael Trenker, Janet M Young, Devin A Cavero, Joseph Hiatt, Theodore L Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M Stroud, Alan D Frankel, Oren S Rosenberg, Kliment A Verba, David A Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark Von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe D'Enfert, Shaeri Mukherjee, Matthew P Jacobson, Harmit Singh Malik, Danica G Fujimori, Trey Ideker, Charles S Craik, Stephen N Floor, Brian K Shoichet, John D Gross, Andrej Sali, Bryan L Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M Shokat, Brian K Shoichet, Nevan J Krogan
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature 583 (7816) (2020)
David E Gordon, Joseph Hiatt, Mehdi Bouhaddou, Veronica V Rezelj, Svenja Ulferts, Hannes Braberg, Alexander S Jureka, Kirsten Obernier, Jeffrey Z Guo, Jyoti Batra, Robyn M Kaake, Andrew R Weckstein, Tristan W Owens, Meghna Gupta, Sergei Pourmal, Erron W Titus, Merve Cakir, Margaret Soucheray, Michael J McGregor, Zeynep Cakir, Gwendolyn M Jang, Matthew J O'Meara, Tia A Tummino, Ziyang Zhang, Helene Foussard, Ajda Rojc, Yuan Zhou, Dmitry Kuchenov, Ruth Hüttenhain, Jiewei Xu, Manon Eckhardt, Danielle L Swaney, Jacqueline M Fabius, Manisha Ummadi, Beril Tutuncuoglu, Ujjwal Rathore, Maya Modak, Paige Haas, Kelsey M Haas, Zun Zar Chi Naing, Ernst H Pulido, Ying Shi, Inigo Barrio-Hernandez, Danish Memon, Eirini Petsalaki, Alistair S Dunham, Miguel Correa Marrero, David Francis Burke, Cassandra Koh, Thomas Vallet, Jesus A Silvas, Caleigh M Azumaya, Christian B Billesbølle, Axel F Brilot, Melody G Campbell, Amy Diallo, Miles Sasha Dickinson, Devan Diwanji, Nadia Herrera, Nicholas Hoppe, Huong T Kratochvil, Yanxin Liu, Gregory E Merz, Michelle Moritz, Henry C Nguyen, Carlos A Nowotny, Cristina Puchades, Alexandrea N Rizo, Ursula Schulze-Gahmen, Amber M Smith, Ming Sun, Iris D Young, Jianhua Zhao, Daniel Asarnow, Justin T Biel, Alisa Bowen, Julian R Braxton, Jen Chen, Cynthia M Chio, Un Seng Chio, Ishan Deshpande, Loan Doan, Bryan Faust, Sebastian Flores, Mingliang Jin, Sun Kyung Kim, Victor L Lam, Fei Li, Junrui Li, Grant J Jensen, Yang Li, Xi Liu, Megan Lo, Kyle E Lopez, Arthur A Melo, Frank R Moss, Phuong Nguyen, Joana Paulino, Komal Ishwar Pawar, Jessica K Peters, Thomas H Pospiech, Maliheh Safari, Smriti Sangwan, Kaitlin Schaefer, Paul V Thomas, Aye C Thwin, Raphael Trenker, Eric Tse, Tsz Kin Martin Tsui, Feng Wang, Natalie Whitis, Zanlin Yu, Kaihua Zhang, Sunny Zhang, Fengbo Zhou, Daniel J Saltzberg, null null, Anthony J Hodder, Amber S Shun-Shion, Daniel M Williams, Kris M White, Romel Rosales, Thomas Kehrer, Lisa Miorin, Elena Moreno, Arvind H Patel, Suzannah J Rihn, Mir Mubashir Khalid, Albert Vallejo-Gracia, Parinaz Fozouni, Camille R Simoneau, Theodore L Roth, David Wu, Mohd Anisul Karim, Maya Ghoussaini, Ian Dunham, Francesco Berardi, Sebastian Weigang, Maxime Chazal, Jisoo Park, James P Logue, Marisa E McGrath, Stuart M Weston, Robert E Haupt, C James Hastie, Matthew Elliott, Fiona Brown, Kerry A Burness, Elaine Reid, Mark Dorward, Clare Johnson, Stuart G Wilkinson, Anna Geyer, Daniel M Giesel, Carla Baillie, Samantha Raggett, Hannah Leech, Rachel Toth, Nicola Goodman, Kathleen C Keough, Abigail L Lind, null null, Reyna J Klesh, Kafi R Hemphill, Jared Carlson-Stevermer, Jennifer Oki, Kevin Holden, Travis Maures, Katherine S Pollard, Andrej Sali, David A Agard, Yifan Cheng, Brian K Shoichet, Adam Frost, Natalia Jura, Tanja Kortemme, Aashish Manglik, Daniel R Southworth, Robert M Stroud, Dario R Alessi, Paul Davies, Matthew B Friemann, Trey Ideker, Carmen Abate, Nolwenn Jouvenet, Georg Kochs, Brian K Shoichet, Melanie M Ott, Massimo Palmarini, Kevan M Shokat, Adolfo García-Sastre, Jeremy A Rassen, Robert Grosse, Oren S Rosenberg, Kliment A Verba, Christopher F Basler, Marco Vignuzzi, Andrew A Peden, Pedro Beltrao, Nevan J Krogan
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.) 370 (6521) (2020)
Yoko Katsuno, Dominique Stephan Meyer, Ziyang Zhang, Kevan M Shokat, Rosemary J Akhurst, Kohei Miyazono, Rik Derynck
Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition. Science signaling 12 (570) (2019)
Ziyang Zhang, Kevan M Shokat
Bifunctional Small-Molecule Ligands of K-Ras Induce Its Association with Immunophilin Proteins. Angewandte Chemie (International ed. in English) 58 (45) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ziyang Zhang