David Leys

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 21

Top Topics

Molecular Dynamics Simulations

Wastewater Treatment

Top Venues

Nature communications

Angewandte Chemie (International ed. in English)

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Shaowei Zhang, Laura N Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O Johannissen, Lingyun Zhu, Matthew J Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W Levy, David Leys, Derren J Heyes, Nigel S Scrutton
Photocobilins integrate B 12 and bilin photochemistry for enzyme control. Nature communications 15 (1) (2024)
Shaowei Zhang, Laura N Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O Johannissen, Lingyun Zhu, Matthew J Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W Levy, David Leys, Derren J Heyes, Nigel S Scrutton
Photocobilins integrate B 12 and bilin photochemistry for enzyme control. Nature communications 15 (1) (2024)
Shaowei Zhang, Laura N Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O Johannissen, Lingyun Zhu, Matthew J Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W Levy, David Leys, Derren J Heyes, Nigel S Scrutton
Photocobilins integrate B 12 and bilin photochemistry for enzyme control. Nature communications 15 (1) (2024)
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O Johannissen, Colin W Levy, Laura N Jeffreys, Shaowei Zhang, Michiyo Sakuma, Jacques-Philippe Colletier, Sam Hay, Giorgio Schirò, Martin Weik, Nigel S Scrutton, David Leys
Redox driven B 12 -ligand switch drives CarH photoresponse. Nature communications 14 (1) (2023)
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys, David J Procter
A Vitamin B 2 -Photocatalysed Approach to Methionine Analogues. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (50) (2022)
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys, David J Procter
A Vitamin B 2 -Photocatalysed Approach to Methionine Analogues. Angewandte Chemie (International ed. in English) 61 (50) (2022)
Samuel Bloor, Iaroslav Michurin, Gabriel R Titchiner, David Leys
Prenylated flavins: structures and mechanisms. The FEBS journal (2022)
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys, David J Procter
A Vitamin B 2 -Photocatalysed Approach to Methionine Analogues. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 134 (50) (2022)
Godwin A Aleku, Gabriel R Titchiner, George W Roberts, Sasha R Derrington, James R Marshall, Florian Hollfelder, Nicholas J Turner, David Leys
Enzymatic N -Allylation of Primary and Secondary Amines Using Renewable Cinnamic Acids Enabled by Bacterial Reductive Aminases. ACS sustainable chemistry & engineering 10 (20) (2022)
Stephen A Marshall, Karl A P Payne, Karl Fisher, Gabriel R Titchiner, Colin Levy, Sam Hay, David Leys
UbiD domain dynamics underpins aromatic decarboxylation. Nature communications 12 (1) (2021)
Hanan L Messiha, Karl A P Payne, Nigel S Scrutton, David Leys
A Biological Route to Conjugated Alkenes: Microbial Production of Hepta-1,3,5-triene. ACS synthetic biology 10 (2) (2021)
Annica Saaret, Benoît Villiers, François Stricher, Macha Anissimova, Mélodie Cadillon, Reynard Spiess, Sam Hay, David Leys
Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production. Nature communications 12 (1) (2021)
Arune Balaikaite, Malama Chisanga, Karl Fisher, Derren J Heyes, Reynard Spiess, David Leys
Ferulic Acid Decarboxylase Controls Oxidative Maturation of the Prenylated Flavin Mononucleotide Cofactor. ACS chemical biology 15 (9) (2020)
David Leys, Nigel S Scrutton
Flavin doesn't put all oxygens in one basket. Nature chemical biology 16 (5) (2020)
Godwin A Aleku, Annica Saaret, Ruth T Bradshaw-Allen, Sasha R Derrington, Gabriel R Titchiner, Irina Gostimskaya, Deepankar Gahloth, David A Parker, Sam Hay, David Leys
Enzymatic C-H activation of aromatic compounds through CO2 fixation. Nature chemical biology 16 (11) (2020)
Samuel S Bailey, Karl A P Payne, Annica Saaret, Stephen A Marshall, Irina Gostimskaya, Iaroslav Kosov, Karl Fisher, Sam Hay, David Leys
Enzymatic control of cycloadduct conformation ensures reversible 1,3-dipolar cycloaddition in a prFMN-dependent decarboxylase. Nature chemistry 11 (11) (2019)
Fraser A Collins, Karl Fisher, Karl A P Payne, Samantha Gaytan Mondragon, Stephen E J Rigby, David Leys
NADPH-Driven Organohalide Reduction by a Nonrespiratory Reductive Dehalogenase. Biochemistry 57 (25) (2018)
Bat-Erdene Jugder, Karl A P Payne, Karl Fisher, Susanne Bohl, Helene Lebhar, Mike Manefield, Matthew Lee, David Leys, Christopher P Marquis
Heterologous Production and Purification of a Functional Chloroform Reductive Dehalogenase. ACS chemical biology 13 (3) (2018)
Stefan E Payer, Stephen A Marshall, Natalie Bärland, Xiang Sheng, Tamara Reiter, Andela Dordic, Georg Steinkellner, Christiane Wuensch, Susann Kaltwasser, Karl Fisher, Stephen E J Rigby, Peter Macheroux, Janet Vonck, Karl Gruber, Kurt Faber, Fahmi Himo, David Leys, Tea Pavkov-Keller, Silvia M Glueck
Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase. Angewandte Chemie (International ed. in English) 56 (44) (2017)
Antonios Lygidakis, Vijaykumar Karuppiah, Robin Hoeven, Aisling Ní Cheallaigh, David Leys, John M Gardiner, Helen S Toogood, Nigel S Scrutton
Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angewandte Chemie (International ed. in English) 55 (33) (2016)
Antonios Lygidakis, Vijaykumar Karuppiah, Robin Hoeven, Aisling Ní Cheallaigh, David Leys, John M Gardiner, Helen S Toogood, Nigel S Scrutton
Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 128 (33) (2016)