David R Boyer (David Boyer)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 18

Top Topics

Electron Microscopy

Cognitive Decline

Protein Protein

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Research square

This page only lists publications with an associated author ORCID identifier.

Publications

David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nature communications 14 (1) (2023)
Gregory M Rosenberg, Romany Abskharon, David R Boyer, Peng Ge, Michael R Sawaya, David S Eisenberg
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. PNAS nexus 2 (12) (2023)
Romany Abskharon, Hope Pan, Michael R Sawaya, Paul Matthew Seidler, Eileen J Olivares, Yu Chen, Kevin A Murray, Jeffrey Zhang, Carter Lantz, Megan Bentzel, David R Boyer, Duilio Cascio, Binh A Nguyen, Ke Hou, Xinyi Cheng, Els Pardon, Christopher K Williams, Alissa L Nana, Harry V Vinters, Salvatore Spina, Lea Tenenholz Grinberg, William W Seeley, Jan Steyaert, Charles G Glabe, Rachel R Ogorzalek Loo, Joseph A Loo, David S Eisenberg
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proceedings of the National Academy of Sciences of the United States of America 120 (41) (2023)
Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nature communications 14 (1) (2023)
Romany Abskharon, Michael R Sawaya, David R Boyer, Qin Cao, Binh A Nguyen, Duilio Cascio, David S Eisenberg
Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. Proceedings of the National Academy of Sciences of the United States of America 119 (15) (2022)
Paul M Seidler, Kevin A Murray, David R Boyer, Peng Ge, Michael R Sawaya, Carolyn J Hu, Xinyi Cheng, Romany Abskharon, Hope Pan, Michael A DeTure, Christopher K Williams, Gourisankar Ghosh, Harry V Vinters, David S Eisenberg
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro. Nature communications 13 (1) (2022)
Catharine C Shipps, H Ray Kelly, Peter J Dahl, Sophia M Yi, Dennis Vu, David R Boyer, Calina Glynn, Michael R Sawaya, David S Eisenberg, Victor S Batista, Nikhil S Malvankar
Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines. Proceedings of the National Academy of Sciences of the United States of America 118 (2) (2021)
Qin Cao, David R Boyer, Michael R Sawaya, Romany Abskharon, Lorena Saelices, Binh An Nguyen, Jiahui Lu, Kevin A Murray, Fouad Kandeel, David S Eisenberg
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. Nature structural & molecular biology 28 (9) (2021)
David R Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, Kang Zhou, Michael P Hughes, Michael R Sawaya, Lin Jiang, David S Eisenberg
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure. Proceedings of the National Academy of Sciences of the United States of America 117 (7) (2020)
Jiahui Lu, Qin Cao, Michael P Hughes, Michael R Sawaya, David R Boyer, Duilio Cascio, David S Eisenberg
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nature communications 11 (1) (2020)
Qin Cao, David R Boyer, Michael R Sawaya, Peng Ge, David S Eisenberg
Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nature structural & molecular biology 27 (7) (2020)
David R Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, Michael R Sawaya, Lin Jiang, David S Eisenberg
Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs. Nature structural & molecular biology 26 (11) (2019)
Qin Cao, David R Boyer, Michael R Sawaya, Peng Ge, David S Eisenberg
Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nature structural & molecular biology 26 (7) (2019)
Binsen Li, Peng Ge, Kevin A Murray, Phorum Sheth, Meng Zhang, Gayatri Nair, Michael R Sawaya, Woo Shik Shin, David R Boyer, Shulin Ye, David S Eisenberg, Z Hong Zhou, Lin Jiang
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. Nature communications 9 (1) (2018)
Michael P Hughes, Michael R Sawaya, David R Boyer, Lukasz Goldschmidt, José A Rodriguez, Duilio Cascio, Lisa Chong, Tamir Gonen, David S Eisenberg
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks. Science (New York, N.Y.) 359 (6376) (2018)