Michael R Sawaya (Michael Sawaya)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 61

Top Venues

Nature communications

Nature structural & molecular biology

Acta crystallographica. Section F, Structural biology communications

Acta crystallographica. Section D, Structural biology

University of California Los Angeles

University of California San Diego (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of California Los Angeles Feb 01 2000

United States

Research Faculty :: Molecular Biology Institute

Harvard Medical School Jun 01 1997 - Jan 29 2000

United States

Postdoctoral Fellow :: Biological Chemistry and Molecular Pharmacology

University of California San Diego Dec 15 1994 - May 15 1997

United States

Postdoctoral fellow :: Chemistry

Education History

University of California San Diego Sep 15 1989 - Dec 07 1994

United States

PHD :: Chemistry

San Diego State University Aug 05 1985 - Aug 15 1985

United States

BSC :: Chemistry

Publications

Matthew P Agdanowski, Roger Castells-Graells, Michael R Sawaya, Duilio Cascio, Todd O Yeates, Mark A Arbing
X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta crystallographica. Section F, Structural biology communications 80 (Pt 5) (2024)
Matthew P Agdanowski, Roger Castells-Graells, Michael R Sawaya, Duilio Cascio, Todd O Yeates, Mark A Arbing
X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta crystallographica. Section F, Structural biology communications 80 (Pt 5) (2024)
Justin E Miller, Matthew P Agdanowski, Joshua L Dolinsky, Michael R Sawaya, Duilio Cascio, Jose A Rodriguez, Todd O Yeates
AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta crystallographica. Section D, Structural biology 80 (Pt 4) (2024)
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria Del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Román González-Prieto, Michael R Sawaya, David S Eisenberg, Merrill Douglas Benson, Lorena Saelices
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nature communications 15 (1) (2024)
Matthew P Agdanowski, Roger Castells-Graells, Michael R Sawaya, Duilio Cascio, Todd O Yeates, Mark A Arbing
X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta crystallographica. Section F, Structural biology communications (2024)
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria Del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Román González-Prieto, Michael R Sawaya, David S Eisenberg, Merrill Douglas Benson, Lorena Saelices
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nature communications 15 (1) (2024)
David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria Del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Román González-Prieto, Michael R Sawaya, David S Eisenberg, Merrill Douglas Benson, Lorena Saelices
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nature communications 15 (1) (2024)
Justin E Miller, Matthew P Agdanowski, Joshua L Dolinsky, Michael R Sawaya, Duilio Cascio, Jose A Rodriguez, Todd O Yeates
AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta crystallographica. Section D, Structural biology 80 (Pt 4) (2024)
Ke Hou, Hope Pan, Hedieh Shahpasand-Kroner, Carolyn Hu, Romany Abskharon, Paul Matthew Seidler, Marisa Mekkittikul, Melinda Balbirnie, Carter Lantz, Michael R Sawaya, Joshua L Dolinsky, Mychica Jones, Xiaohong Zuo, Joseph A Loo, Sally A Frautschy, Gregory M Cole, David S Eisenberg
D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease. Science advances 10 (18) (2024)
Matthew P Agdanowski, Roger Castells-Graells, Michael R Sawaya, Duilio Cascio, Todd O Yeates, Mark A Arbing
X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta crystallographica. Section F, Structural biology communications 80 (Pt 5) (2024)
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria Del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Román González-Prieto, Michael R Sawaya, David S Eisenberg, Merrill Douglas Benson, Lorena Saelices
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nature communications 15 (1) (2024)
Ke Hou, Hope Pan, Hedieh Shahpasand-Kroner, Carolyn Hu, Romany Abskharon, Paul Matthew Seidler, Marisa Mekkittikul, Melinda Balbirnie, Carter Lantz, Michael R Sawaya, Joshua L Dolinsky, Mychica Jones, Xiaohong Zuo, Joseph A Loo, Sally A Frautschy, Gregory M Cole, David S Eisenberg
D-peptide-magnetic nanoparticles fragment tau fibrils and rescue behavioral deficits in a mouse model of Alzheimer's disease. Science advances 10 (18) (2024)
Justin E Miller, Matthew P Agdanowski, Joshua L Dolinsky, Michael R Sawaya, Duilio Cascio, Jose A Rodriguez, Todd O Yeates
AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta crystallographica. Section D, Structural biology (2024)
David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
Binh An Nguyen, Virender Singh, Shumaila Afrin, Anna Yakubovska, Lanie Wang, Yasmin Ahmed, Rose Pedretti, Maria Del Carmen Fernandez-Ramirez, Preeti Singh, Maja Pękała, Luis O Cabrera Hernandez, Siddharth Kumar, Andrew Lemoff, Román González-Prieto, Michael R Sawaya, David S Eisenberg, Merrill Douglas Benson, Lorena Saelices
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy. Nature communications 15 (1) (2024)
David S Eisenberg, Ke Hou, Peng Ge, Michael R Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David R Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon
How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism. Research square (2024)
Justin E Miller, Matthew P Agdanowski, Joshua L Dolinsky, Michael R Sawaya, Duilio Cascio, Jose A Rodriguez, Todd O Yeates
AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta crystallographica. Section D, Structural biology 80 (Pt 4) (2024)
Logan S Richards, Maria D Flores, Claudia Millán, Calina Glynn, Chih-Te Zee, Michael R Sawaya, Marcus Gallagher-Jones, Rafael J Borges, Isabel Usón, José A Rodríguez
Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. ACS bio & med chem Au 3 (2) (2023)
Logan S Richards, Maria D Flores, Claudia Millán, Calina Glynn, Chih-Te Zee, Michael R Sawaya, Marcus Gallagher-Jones, Rafael J Borges, Isabel Usón, José A Rodríguez
Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. ACS bio & med chem Au 3 (2) (2023)
Amaruka Hazari, Michael R Sawaya, Maria Sajimon, Niko Vlahakis, Jose Rodriguez, David Eisenberg, Jevgenij A Raskatov
Racemic Peptides from Amyloid β and Amylin Form Rippled β-Sheets Rather Than Pleated β-Sheets. Journal of the American Chemical Society (2023)
Andrew Stewart, Philip Dershwitz, Charles Stewart, Michael R Sawaya, Todd O Yeates, Jeremy D Semrau, Hans Zischka, Alan A DiSpirito, Thomas A Bobik
Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2. Acta crystallographica. Section F, Structural biology communications 79 (Pt 5) (2023)
Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nature communications 14 (1) (2023)
Kyle Meador, Roger Castells-Graells, Roman Aguirre, Michael R Sawaya, Mark A Arbing, Trent Sherman, Chethaka Senarathne, Todd O Yeates
A Suite of Designed Protein Cages Using Machine Learning Algorithms and Protein Fragment-Based Protocols. bioRxiv : the preprint server for biology (2023)
Andrew Stewart, Philip Dershwitz, Charles Stewart, Michael R Sawaya, Todd O Yeates, Jeremy D Semrau, Hans Zischka, Alan A DiSpirito, Thomas A Bobik
Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2. Acta crystallographica. Section F, Structural biology communications 79 (Pt 5) (2023)
Gregory M Rosenberg, Romany Abskharon, David R Boyer, Peng Ge, Michael R Sawaya, David S Eisenberg
Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. PNAS nexus 2 (12) (2023)
Logan S Richards, Maria D Flores, Claudia Millán, Calina Glynn, Chih-Te Zee, Michael R Sawaya, Marcus Gallagher-Jones, Rafael J Borges, Isabel Usón, José A Rodríguez
Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. ACS bio & med chem Au 3 (2) (2023)
Romany Abskharon, Hope Pan, Michael R Sawaya, Paul Matthew Seidler, Eileen J Olivares, Yu Chen, Kevin A Murray, Jeffrey Zhang, Carter Lantz, Megan Bentzel, David R Boyer, Duilio Cascio, Binh A Nguyen, Ke Hou, Xinyi Cheng, Els Pardon, Christopher K Williams, Alissa L Nana, Harry V Vinters, Salvatore Spina, Lea Tenenholz Grinberg, William W Seeley, Jan Steyaert, Charles G Glabe, Rachel R Ogorzalek Loo, Joseph A Loo, David S Eisenberg
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proceedings of the National Academy of Sciences of the United States of America 120 (41) (2023)
Logan S Richards, Maria D Flores, Claudia Millán, Calina Glynn, Chih-Te Zee, Michael R Sawaya, Marcus Gallagher-Jones, Rafael J Borges, Isabel Usón, José A Rodríguez
Fragment-Based Ab Initio Phasing of Peptidic Nanocrystals by MicroED. ACS bio & med chem Au 3 (2) (2023)
Roger Castells-Graells, Kyle Meador, Mark A Arbing, Michael R Sawaya, Morgan Gee, Duilio Cascio, Emma Gleave, Judit É Debreczeni, Jason Breed, Karoline Leopold, Ankoor Patel, Dushyant Jahagirdar, Bronwyn Lyons, Sriram Subramaniam, Chris Phillips, Todd O Yeates
Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold. Proceedings of the National Academy of Sciences of the United States of America 120 (37) (2023)
Einav Tayeb-Fligelman, Jeannette T Bowler, Christen E Tai, Michael R Sawaya, Yi Xiao Jiang, Gustavo Garcia, Sarah L Griner, Xinyi Cheng, Lukasz Salwinski, Liisa Lutter, Paul M Seidler, Jiahui Lu, Gregory M Rosenberg, Ke Hou, Romany Abskharon, Hope Pan, Chih-Te Zee, David R Boyer, Yan Li, Daniel H Anderson, Kevin A Murray, Genesis Falcon, Duilio Cascio, Lorena Saelices, Robert Damoiseaux, Vaithilingaraja Arumugaswami, Feng Guo, David S Eisenberg
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nature communications 14 (1) (2023)
Andrew Stewart, Philip Dershwitz, Charles Stewart, Michael R Sawaya, Todd O Yeates, Jeremy D Semrau, Hans Zischka, Alan A DiSpirito, Thomas A Bobik
Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2. Acta crystallographica. Section F, Structural biology communications 79 (Pt 5) (2023)
Guillaume Tetreau, Michael R Sawaya, Elke De Zitter, Elena A Andreeva, Anne-Sophie Banneville, Natalie A Schibrowsky, Nicolas Coquelle, Aaron S Brewster, Marie Luise Grünbein, Gabriela Nass Kovacs, Mark S Hunter, Marco Kloos, Raymond G Sierra, Giorgio Schiro, Pei Qiao, Myriam Stricker, Dennis Bideshi, Iris D Young, Ninon Zala, Sylvain Engilberge, Alexander Gorel, Luca Signor, Jean-Marie Teulon, Mario Hilpert, Lutz Foucar, Johan Bielecki, Richard Bean, Raphael de Wijn, Tokushi Sato, Henry J Kirkwood, Romain Letrun, Alexander Batyuk, Irina Snigireva, Daphna Fenel, Robin Schubert, Ethan J Canfield, Mario M Alba, Frédéric Laporte, Laurence Després, Maria Bacia, Amandine Roux, Christian Chapelle, François Riobé, Olivier Maury, Wai Li Ling, Sébastien Boutet, Adrian Mancuso, Irina Gutsche, Eric Girard, Thomas R M Barends, Jean-Luc Pellequer, Hyun-Woo Park, Arthur D Laganowsky, Jose Rodriguez, Manfred Burghammer, Robert L Shoeman, R Bruce Doak, Martin Weik, Nicholas K Sauter, Brian Federici, Duilio Cascio, Ilme Schlichting, Jacques-Philippe Colletier
De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nature communications 13 (1) (2022)
Yi Xiao Jiang, Qin Cao, Michael R Sawaya, Romany Abskharon, Peng Ge, Michael DeTure, Gourisankar Ghosh, Janine Y Fu, Rachel R Ogorzalek Loo, Joseph A Loo, David S Eisenberg
Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43. Nature 605 (7909) (2022)
Kevin A Murray, Declan Evans, Michael P Hughes, Michael R Sawaya, Carolyn J Hu, Kendall N Houk, David Eisenberg
Extended β-Strands Contribute to Reversible Amyloid Formation. ACS nano 16 (2) (2022)
Kevin A Murray, Michael P Hughes, Carolyn J Hu, Michael R Sawaya, Lukasz Salwinski, Hope Pan, Samuel W French, Paul M Seidler, David S Eisenberg
Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nature structural & molecular biology 29 (6) (2022)
Romany Abskharon, Michael R Sawaya, David R Boyer, Qin Cao, Binh A Nguyen, Duilio Cascio, David S Eisenberg
Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation. Proceedings of the National Academy of Sciences of the United States of America 119 (15) (2022)
Paul M Seidler, Kevin A Murray, David R Boyer, Peng Ge, Michael R Sawaya, Carolyn J Hu, Xinyi Cheng, Romany Abskharon, Hope Pan, Michael A DeTure, Christopher K Williams, Gourisankar Ghosh, Harry V Vinters, David S Eisenberg
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro. Nature communications 13 (1) (2022)
Catharine C Shipps, H Ray Kelly, Peter J Dahl, Sophia M Yi, Dennis Vu, David R Boyer, Calina Glynn, Michael R Sawaya, David S Eisenberg, Victor S Batista, Nikhil S Malvankar
Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines. Proceedings of the National Academy of Sciences of the United States of America 118 (2) (2021)
Qin Cao, David R Boyer, Michael R Sawaya, Romany Abskharon, Lorena Saelices, Binh An Nguyen, Jiahui Lu, Kevin A Murray, Fouad Kandeel, David S Eisenberg
Cryo-EM structures of hIAPP fibrils seeded by patient-extracted fibrils reveal new polymorphs and conserved fibril cores. Nature structural & molecular biology 28 (9) (2021)
Jessica M Ochoa, Oscar Mijares, Andrea A Acosta, Xavier Escoto, Nancy Leon-Rivera, Joanna D Marshall, Michael R Sawaya, Todd O Yeates
Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments. Acta crystallographica. Section F, Structural biology communications 77 (Pt 9) (2021)
Saken Sherkhanov, Tyler P Korman, Sum Chan, Salem Faham, Hongjiang Liu, Michael R Sawaya, Wan-Ting Hsu, Ellee Vikram, Tiffany Yi-Mei Cheng, James U Bowie
Isobutanol production freed from biological limits using synthetic biochemistry. Nature communications 11 (1) (2020)
Romany Abskharon, Paul Matthew Seidler, Michael R Sawaya, Duilio Cascio, Tianxiao P Yang, Stephan Philipp, Christopher Kazu Williams, Kathy L Newell, Bernardino F Ghetti, Michael A DeTure, Dennis W Dickson, Harry V Vinters, Philip L Felgner, Rie Nakajima, Charles G Glabe, David S Eisenberg
Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. The Journal of biological chemistry 295 (31) (2020)
Jiahui Lu, Qin Cao, Michael P Hughes, Michael R Sawaya, David R Boyer, Duilio Cascio, David S Eisenberg
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid. Nature communications 11 (1) (2020)
Calina Glynn, Michael R Sawaya, Peng Ge, Marcus Gallagher-Jones, Connor W Short, Ronquiajah Bowman, Marcin Apostol, Z Hong Zhou, David S Eisenberg, José A Rodriguez
Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core. Nature structural & molecular biology 27 (5) (2020)
Guillaume Tetreau, Anne-Sophie Banneville, Elena A Andreeva, Aaron S Brewster, Mark S Hunter, Raymond G Sierra, Jean-Marie Teulon, Iris D Young, Niamh Burke, Tilman A Grünewald, Joël Beaudouin, Irina Snigireva, Maria Teresa Fernandez-Luna, Alister Burt, Hyun-Woo Park, Luca Signor, Jayesh A Bafna, Rabia Sadir, Daphna Fenel, Elisabetta Boeri-Erba, Maria Bacia, Ninon Zala, Frédéric Laporte, Laurence Després, Martin Weik, Sébastien Boutet, Martin Rosenthal, Nicolas Coquelle, Manfred Burghammer, Duilio Cascio, Michael R Sawaya, Mathias Winterhalter, Enrico Gratton, Irina Gutsche, Brian Federici, Jean-Luc Pellequer, Nicholas K Sauter, Jacques-Philippe Colletier
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade. Nature communications 11 (1) (2020)
Qin Cao, David R Boyer, Michael R Sawaya, Peng Ge, David S Eisenberg
Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nature structural & molecular biology 27 (7) (2020)
David R Boyer, Binsen Li, Chuanqi Sun, Weijia Fan, Michael R Sawaya, Lin Jiang, David S Eisenberg
Structures of fibrils formed by α-synuclein hereditary disease mutant H50Q reveal new polymorphs. Nature structural & molecular biology 26 (11) (2019)
Vasantha Basavalingappa, Santu Bera, Bin Xue, Ido Azuri, Yiming Tang, Kai Tao, Linda J W Shimon, Michael R Sawaya, Sofiya Kolusheva, David S Eisenberg, Leeor Kronik, Yi Cao, Guanghong Wei, Ehud Gazit
Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nature communications 10 (1) (2019)
Rebeccah A Warmack, David R Boyer, Chih-Te Zee, Logan S Richards, Michael R Sawaya, Duilio Cascio, Tamir Gonen, David S Eisenberg, Steven G Clarke
Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. Nature communications 10 (1) (2019)
Paul Matthew Seidler, David R Boyer, Kevin A Murray, Tianxiao P Yang, Megan Bentzel, Michael R Sawaya, Gregory Rosenberg, Duilio Cascio, Christopher Kazu Williams, Kathy L Newell, Bernardino Ghetti, Michael A DeTure, Dennis W Dickson, Harry V Vinters, David S Eisenberg
Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. The Journal of biological chemistry 294 (44) (2019)
Chih-Te Zee, Calina Glynn, Marcus Gallagher-Jones, Jennifer Miao, Carlos G Santiago, Duilio Cascio, Tamir Gonen, Michael R Sawaya, José A Rodríguez
Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ. IUCrJ 6 (Pt 2) (2019)
Qin Cao, David R Boyer, Michael R Sawaya, Peng Ge, David S Eisenberg
Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nature structural & molecular biology 26 (7) (2019)
Michele D Kattke, Jason E Gosschalk, Orlando E Martinez, Garima Kumar, Robert T Gale, Duilio Cascio, Michael R Sawaya, Martin Philips, Eric D Brown, Robert T Clubb
Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria. PLoS pathogens 15 (4) (2019)
Elizabeth L Guenther, Qin Cao, Hamilton Trinh, Jiahui Lu, Michael R Sawaya, Duilio Cascio, David R Boyer, José A Rodriguez, Michael P Hughes, David S Eisenberg
Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nature structural & molecular biology 25 (6) (2018)
Binsen Li, Peng Ge, Kevin A Murray, Phorum Sheth, Meng Zhang, Gayatri Nair, Michael R Sawaya, Woo Shik Shin, David R Boyer, Shulin Ye, David S Eisenberg, Z Hong Zhou, Lin Jiang
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. Nature communications 9 (1) (2018)
Qin Cao, Woo Shik Shin, Henry Chan, Celine K Vuong, Bethany Dubois, Binsen Li, Kevin A Murray, Michael R Sawaya, Juli Feigon, Douglas L Black, David S Eisenberg, Lin Jiang
Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design. Nature chemistry 10 (12) (2018)
Michael P Hughes, Michael R Sawaya, David R Boyer, Lukasz Goldschmidt, José A Rodriguez, Duilio Cascio, Lisa Chong, Tamir Gonen, David S Eisenberg
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks. Science (New York, N.Y.) 359 (6376) (2018)
Laura McPartland, Danielle M Heller, David S Eisenberg, Ann Hochschild, Michael R Sawaya
Atomic insights into the genesis of cellular filaments by globular proteins. Nature structural & molecular biology 25 (8) (2018)
Pascal Krotee, Jose A Rodriguez, Michael R Sawaya, Duilio Cascio, Francis E Reyes, Dan Shi, Johan Hattne, Brent L Nannenga, Marie E Oskarsson, Stephan Philipp, Sarah Griner, Lin Jiang, Charles G Glabe, Gunilla T Westermark, Tamir Gonen, David S Eisenberg
Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity. eLife 6 (2017)
Einav Tayeb-Fligelman, Orly Tabachnikov, Asher Moshe, Orit Goldshmidt-Tran, Michael R Sawaya, Nicolas Coquelle, Jacques-Philippe Colletier, Meytal Landau
The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril. Science (New York, N.Y.) 355 (6327) (2017)

Michael R Sawaya.css-eqlu8i{font-size:small;padding-left:4px;} (Michael Sawaya)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael R Sawaya (Michael Sawaya)