Diane Ramsden

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2023
Publications (10 Years): 10

Top Venues

Drug metabolism and disposition: the biological fate of chemicals

European journal of drug metabolism and pharmacokinetics

Clinical pharmacology and therapeutics

Xenobiotica; the fate of foreign compounds in biological systems

Alnylam Pharmaceuticals Inc

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Alnylam Pharmaceuticals Inc Jan 16o 2018

United States

Senior Scientist :: Early Development (DMPK)

Publications

Paresh P Chothe, Vikram Arya, Bhagwat Prasad, Diane Ramsden, Kunal Taskar
Innovations, Opportunities and Challenges for Predicting Alteration in Drug Metabolizing Enzymes and Transporters Activity in Specific Populations . Drug metabolism and disposition: the biological fate of chemicals (2023)
Sandeepraj Pusalkar, Swapan K Chowdhury, Richard Czerniak, Xiaochun Zhu, Yuexian Li, Suresh K Balani, Diane Ramsden
Clinical and Nonclinical Disposition and In Vitro Drug-Drug Interaction Potential of Felcisetrag, a Highly Selective and Potent 5-HT 4 Receptor Agonist. European journal of drug metabolism and pharmacokinetics 47 (3) (2022)
Diane Ramsden, Cody L Fullenwider
Characterization of Correction Factors to Enable Assessment of Clinical Risk from In Vitro CYP3A4 Induction Data and Basic Drug-Drug Interaction Models. European journal of drug metabolism and pharmacokinetics 47 (4) (2022)
Srinivasan Krishnan, Diane Ramsden, Douglas Ferguson, Simone H Stahl, Joanne Wang, Dermot F McGinnity, Niresh Hariparsad
Challenges and Opportunities for Improved Drug-Drug Interaction Predictions for Renal OCT2 and MATE1/2-K Transporters. Clinical pharmacology and therapeutics 112 (3) (2022)
Mitsuhiro Nishihara, Diane Ramsden, Suresh K Balani
Evaluation of the drug-drug interaction potential for trazpiroben (TAK-906), a D2/D3 receptor antagonist for gastroparesis, towards cytochrome P450s and transporters. Xenobiotica; the fate of foreign compounds in biological systems 51 (6) (2021)
Saeho Chong, Sagar Agarwal, Saket Agarwal, Krishna C Aluri, Michael Arciprete, Christopher Brown, Klaus Charisse, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeff Kurz, Jing Li, Steven Liou, Ju Liu, Xiumin Liu, Christopher Maclauchlin, Martin Maier, Muthiah Manoharan, Robin McDougall, Jay Nair, Diane Ramsden, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Jing-Tao Wu, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev, Elena Castellanos-Rizaldos
The Nonclinical Disposition and PK/PD Properties of GalNAc-conjugated siRNA Are Highly Predictable and Build Confidence in Translation to Man. Drug metabolism and disposition: the biological fate of chemicals (2021)
Diane Ramsden, Elke S Perloff, Andrea Whitcher-Johnstone, Thuy Ho, Reena Patel, Kirk D Kozminski, Cody L Fullenwider, J George Zhang
Predictive In Vitro-In Vivo Extrapolation for Time Dependent Inhibition of CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP2D6 Using Pooled Human Hepatocytes, Human Liver Microsomes, and a Simple Mechanistic Static Model. Drug metabolism and disposition: the biological fate of chemicals (2021)
Simon G Wong, Diane Ramsden, Shannon Dallas, Conrad Fung, Heidi J Einolf, Jairam Palamanda, Liangfu Chen, Theunis C Goosen, Y Amy Siu, George Zhang, Donald Tweedie, Niresh Hariparsad, Barry Jones, Phillip D Yates
Considerations from the Innovation and Quality Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Guidelines on Model Fitting and Recommendations on Time Course for In Vitro Cytochrome P450 Induction Studies Including Impact on Drug Interaction Risk Assessment. Drug metabolism and disposition: the biological fate of chemicals 49 (1) (2020)
Diane Ramsden, Jing-Tao Wu, Brad Zerler, Sajida Iqbal, Jim Jiang, Valerie Clausen, Krishna C Aluri, Yongli Gu, Sean Dennin, Joohwan Kim, Saeho Chong
In Vitro Drug-Drug Interaction Evaluation of GalNAc Conjugated siRNAs Against CYP450 Enzymes and Transporters. Drug metabolism and disposition: the biological fate of chemicals 47 (10) (2019)
Diane Ramsden, Conrad Fung, Niresh Hariparsad, Jane R Kenny, Michael Mohutsky, Neil J Parrott, Sarah Robertson, Donald J Tweedie
Perspectives from the Innovation and Quality Consortium Induction Working Group on Factors Impacting Clinical Drug-Drug Interactions Resulting from Induction: Focus on Cytochrome 3A Substrates. Drug metabolism and disposition: the biological fate of chemicals 47 (10) (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

Diane Ramsden