European journal of drug metabolism and pharmacokinetics

Keyphrases

Publications

volume 49, number 3, 2024

Yu Zhu, Chen Li, Liming Chen, Haiyan Liu, Lun Ou, Tong Li, Xuan Wang, Tenghua Wang, Jingyuan Tian, Xintong Liang, Zhiqin Hu, Yaoxuan Zhan, Shuangshuang Xiao, Xiaole Wang, Yongmei Li, Jin He, Qingshan Zheng, Haifeng Song, Xianbo Li, Yi Fang
A Phase I Clinical Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of GB221 Injection and Trastuzumab (Herceptin ® ) in Healthy Chinese Adults. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Hao Wang, Mengdi Song, Jiaqi Xu, Zhenjing Liu, Mingyue Peng, Haoqiang Qin, Shaoqian Wang, Ziyang Wang, Kehai Liu
Long-Acting Strategies for Antibody Drugs: Structural Modification, Controlling Release, and Changing the Administration Route. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Yiming Cheng, Xiaomin Wang, Liangang Liu, Jose Silva, Michael Thomas, Yan Li
A Phase I, Open-Label, Mass Balance Study of [ 14 C]-Iberdomide in Healthy Subjects. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Hao Wang, Mengdi Song, Jiaqi Xu, Zhenjing Liu, Mingyue Peng, Haoqiang Qin, Shaoqian Wang, Ziyang Wang, Kehai Liu
Long-Acting Strategies for Antibody Drugs: Structural Modification, Controlling Release, and Changing the Administration Route. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Slobodan M Jankovic, Snežana V Janković
Anti-calcitonin Gene-Related Peptide Monoclonal Antibodies in Migraine: Focus on Clinical Pharmacokinetics. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Ewelina Gabor-Worwa, Anna Kowal-Chwast, Nilesh Gaud, Dawid Gogola, Peter Littlewood, Marek Smoluch, Krzysztof Brzózka, Kamil Kus
Uridine 5'-Diphospho-glucuronosyltransferase 1A3 (UGT1A3) Prediction of Hepatic Clearance of Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Substrate Telmisartan by Glucuronidation Using In Vitro-In Vivo Extrapolation (IVIVE). European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Xin Song, Minglan Zheng, Heping Hu, Lei Chen, Shuzhe Wang, Zhao Ding, Guangyi Fu, Luyao Sun, Liyuan Zhao, Ling Zhang, Bohua Xu, Yunliang Qiu
Pharmacokinetic Study of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles HY-088 in Rats. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Xiaoxing Wang, Martin E Dowty, Sakambari Tripathy, Vu H Le, Yeamin Huh, Madelyn Curto, Jennifer A Winton, Melissa T O'Gorman, Gary Chan, Bimal K Malhotra
Assessment of the Effects of Abrocitinib on the Pharmacokinetics of Probe Substrates of Cytochrome P450 1A2, 2B6 and 2C19 Enzymes and Hormonal Oral Contraceptives in Healthy Individuals. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)
Chuan-Fei Jin, Chao Yi, Kangzhi Chen, Haiping Liang
Safety, Tolerability, and Pharmacokinetics of the Monoamine Oxidase B Inhibitor, HEC122505, and its Major Metabolite After Single- and Multiple- Ascending Dose, and Food Effect Study in Healthy Chinese Subjects. European journal of drug metabolism and pharmacokinetics 49 (3) (2024)

volume 49, number 4, 2024

Niels Westra, Paul D Kruithof, Sander Croes, Robin M J M van Geel, Lizza E L Hendriks, Daan J Touw, Thijs H Oude Munnink, Paola Mian
Systematic Evaluation of Osimertinib Population Pharmacokinetic Models in a Cohort of Dutch Adults with Non-Small Cell Lung Cancer. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Alejandra Schiavo, Pietro Fagiolino, Marta Vázquez, Iñaki Tróconiz, Manuel Ibarra
Model-Based Bioequivalence Analysis to Assess and Predict the Relative Bioavailability of Valproic Acid Formulations. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Mir Amir Hossein Hosseini, Ali Akbar Alizadeh, Ali Shayanfar
Prediction of the First-Pass Metabolism of a Drug After Oral Intake Based on Structural Parameters and Physicochemical Properties. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Niels Westra, Paul D Kruithof, Sander Croes, Robin M J M van Geel, Lizza E L Hendriks, Daan J Touw, Thijs H Oude Munnink, Paola Mian
Systematic Evaluation of Osimertinib Population Pharmacokinetic Models in a Cohort of Dutch Adults with Non-Small Cell Lung Cancer. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Huybrecht T'jollyn, Raja Venkatasubramanian, Martine Neyens, Srihari Gopal, Alberto Russu, Partha Nandy, Juan Jose Perez-Ruixo, Oliver Ackaert
Model-Informed Clinical Development of 6-Monthly Injection of Paliperidone Palmitate in Patients with Schizophrenia: Dosing Strategies Guided by Population Pharmacokinetic Modeling and Simulation (Part II). European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Lisa T van der Heijden, Frans L Opdam, Jos H Beijnen, Alwin D R Huitema
The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Niels Westra, Paul D Kruithof, Sander Croes, Robin M J M van Geel, Lizza E L Hendriks, Daan J Touw, Thijs H Oude Munnink, Paola Mian
Systematic Evaluation of Osimertinib Population Pharmacokinetic Models in a Cohort of Dutch Adults with Non-Small Cell Lung Cancer. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Mohamed T Khayyal, Mahmoud H Teaima, Hoda M Marzouk, Rania M El -Hazek, Frank Behnam, Dariush Behnam
Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Huybrecht T'jollyn, Alberto Russu, Raja Venkatasubramanian, Srihari Gopal, Partha Nandy, Martine Neyens, Ruben Faelens, Mahesh N Samtani, Oliver Ackaert, Juan Jose Perez-Ruixo
Model-Informed Clinical Development of Once-Every-6-Month Injection of Paliperidone Palmitate in Patients with Schizophrenia: A Pharmacometric Bridging Approach (Part I). European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Lisa T van der Heijden, Frans L Opdam, Jos H Beijnen, Alwin D R Huitema
The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Mehdi El Hassani, Uwe Liebchen, Amélie Marsot
Does Sample Size, Sampling Strategy, or Handling of Concentrations Below the Lower Limit of Quantification Matter When Externally Evaluating Population Pharmacokinetic Models? European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Mohamed T Khayyal, Mahmoud H Teaima, Hoda M Marzouk, Rania M El -Hazek, Frank Behnam, Dariush Behnam
Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Jing Yang, Jinxingyi Wang, Lijie Ning, Changsong Wu, Yang Liu, Jie Xia, Yanping Guan, Qian Liu, Jianghuan Zheng
Influence of UGT2B7, UGT1A4 and ABCG2 Polymorphisms on the Pharmacokinetics and Therapeutic Efficacy of Lamotrigine in Patients with Epilepsy. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Jing Yang, Jinxingyi Wang, Lijie Ning, Changsong Wu, Yang Liu, Jie Xia, Yanping Guan, Qian Liu, Jianghuan Zheng
Influence of UGT2B7, UGT1A4 and ABCG2 Polymorphisms on the Pharmacokinetics and Therapeutic Efficacy of Lamotrigine in Patients with Epilepsy. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Lisa T van der Heijden, Frans L Opdam, Jos H Beijnen, Alwin D R Huitema
The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Mohamed T Khayyal, Mahmoud H Teaima, Hoda M Marzouk, Rania M El -Hazek, Frank Behnam, Dariush Behnam
Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)
Niels Westra, Paul D Kruithof, Sander Croes, Robin M J M van Geel, Lizza E L Hendriks, Daan J Touw, Thijs H Oude Munnink, Paola Mian
Systematic Evaluation of Osimertinib Population Pharmacokinetic Models in a Cohort of Dutch Adults with Non-Small Cell Lung Cancer. European journal of drug metabolism and pharmacokinetics 49 (4) (2024)

volume 49, number 5, 2024

Prajakta Harish Patil, Mrunal Desai, Sumit Birangal, Gautham Shenoy Gurupur, Mahadev Rao, Anandkumar Yadav, Vishwanath Kurawattimath, Avinash Chaudhari, Tarun Sharma, Jakir Pinjari, Puralae Channabasavaiah Jagadish
The Effect of Concomitant Administration of Proton Pump Inhibitors on the Pharmacokinetics of CDK4/6 Inhibitors in Rats: Implications for the Evaluation of Hepatic and Transporter-Mediated Drug-Drug Interactions. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Wenjing Li, Yufan Xue, Feng Zhang, Ling Xiao, Zhu Huang, Wenjuan Li, Liangliang Zhu, Guangbo Ge
In Vitro Ciclopirox Glucuronidation in Liver Microsomes from Humans and Various Experimental Animals. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Wenjing Li, Yufan Xue, Feng Zhang, Ling Xiao, Zhu Huang, Wenjuan Li, Liangliang Zhu, Guangbo Ge
In Vitro Ciclopirox Glucuronidation in Liver Microsomes from Humans and Various Experimental Animals. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Frida S Boer-Pérez, Victoria Lima-Rogel, Ana Ruth Mejía-Elizondo, Susanna Edith Medellín-Garibay, Ana S Rodríguez-Báez, Cristian J Rodríguez-Pinal, Rosa Del Carmen Milán Segovia, Silvia Romano Moreno
External Evaluation of Population Pharmacokinetic Models of Piperacillin in Preterm and Term Patients from Neonatal Intensive Care. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Wenjing Li, Yufan Xue, Feng Zhang, Ling Xiao, Zhu Huang, Wenjuan Li, Liangliang Zhu, Guangbo Ge
In Vitro Ciclopirox Glucuronidation in Liver Microsomes from Humans and Various Experimental Animals. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Olivier Fardel, Amélie Moreau, Jennifer Carteret, Claire Denizot, Marc Le Vée, Yannick Parmentier
The Competitive Counterflow Assay for Identifying Drugs Transported by Solute Carriers: Principle, Applications, Challenges/Limits, and Perspectives. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Fawzy A Elbarbry, Tamer M Ibrahim, Mohamed A Abdelrahman, Claudiu T Supuran, Wagdy M Eldehna
Inhibitory Effect of Two Carbonic Anhydrases Inhibitors on the Activity of Major Cytochrome P450 Enzymes. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Levin Thomas, Arun Prasath Raju, Surulivel Rajan M, Mahadev Rao
Precision Medicine Strategies to Improve Isoniazid Therapy in Patients with Tuberculosis. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Qi Shen, Wenxuan Chen, Wei Wang, Shuyue Kang, Yuxin Du, Jiaxi Shi, Limei Yao, Wei-Rong Li
Drug Interactions between Traditional Chinese Medicines and Cardiovascular Drugs. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Levin Thomas, Arun Prasath Raju, Surulivel Rajan M, Mahadev Rao
Precision Medicine Strategies to Improve Isoniazid Therapy in Patients with Tuberculosis. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Qi Shen, Wenxuan Chen, Wei Wang, Shuyue Kang, Yuxin Du, Jiaxi Shi, Limei Yao, Wei-Rong Li
Drug Interactions between Traditional Chinese Medicines and Cardiovascular Drugs. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Levin Thomas, Arun Prasath Raju, Surulivel Rajan M, Mahadev Rao
Precision Medicine Strategies to Improve Isoniazid Therapy in Patients with Tuberculosis. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Fawzy A Elbarbry, Tamer M Ibrahim, Mohamed A Abdelrahman, Claudiu T Supuran, Wagdy M Eldehna
Inhibitory Effect of Two Carbonic Anhydrases Inhibitors on the Activity of Major Cytochrome P450 Enzymes. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Levin Thomas, Arun Prasath Raju, Surulivel Rajan M, Mahadev Rao
Precision Medicine Strategies to Improve Isoniazid Therapy in Patients with Tuberculosis. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Frida S Boer-Pérez, Victoria Lima-Rogel, Ana Ruth Mejía-Elizondo, Susanna Edith Medellín-Garibay, Ana S Rodríguez-Báez, Cristian J Rodríguez-Pinal, Rosa Del Carmen Milán Segovia, Silvia Romano Moreno
External Evaluation of Population Pharmacokinetic Models of Piperacillin in Preterm and Term Patients from Neonatal Intensive Care. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Fawzy A Elbarbry, Tamer M Ibrahim, Mohamed A Abdelrahman, Claudiu T Supuran, Wagdy M Eldehna
Inhibitory Effect of Two Carbonic Anhydrases Inhibitors on the Activity of Major Cytochrome P450 Enzymes. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Bo-Yu Chen, Jia-Huan Xu, Qian-Qing Chen, Huan-Xian Wu, Bao-Fang Ou, Zhiwei Zhou, Fei Xu, Shao-Yu Wu, Shui-Lin Xie, Ding-Sheng Wen
Pharmacokinetics and Bioavailability Study of a Novel Smoothened Inhibitor TPB15 for Treatment of Triple-Negative Breast Cancer in Rats by High Performance Liquid Chromatography-Mass Spectrometry. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Yuheng Shan, Yuying Cen, Xiaojiao Xu, Ping Li, Jing Chen, Zhiyong Nie, Jiatang Zhang
The ATP-Binding Cassette Transporter-Mediated Efflux Transport of Ganciclovir at the Blood-Brain Barrier. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Yuheng Shan, Yuying Cen, Xiaojiao Xu, Ping Li, Jing Chen, Zhiyong Nie, Jiatang Zhang
The ATP-Binding Cassette Transporter-Mediated Efflux Transport of Ganciclovir at the Blood-Brain Barrier. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Prajakta Harish Patil, Mrunal Desai, Sumit Birangal, Gautham Shenoy Gurupur, Mahadev Rao, Anandkumar Yadav, Vishwanath Kurawattimath, Avinash Chaudhari, Tarun Sharma, Jakir Pinjari, Puralae Channabasavaiah Jagadish
The Effect of Concomitant Administration of Proton Pump Inhibitors on the Pharmacokinetics of CDK4/6 Inhibitors in Rats: Implications for the Evaluation of Hepatic and Transporter-Mediated Drug-Drug Interactions. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Prajakta Harish Patil, Mrunal Desai, Sumit Birangal, Gautham Shenoy Gurupur, Mahadev Rao, Anandkumar Yadav, Vishwanath Kurawattimath, Avinash Chaudhari, Tarun Sharma, Jakir Pinjari, Puralae Channabasavaiah Jagadish
The Effect of Concomitant Administration of Proton Pump Inhibitors on the Pharmacokinetics of CDK4/6 Inhibitors in Rats: Implications for the Evaluation of Hepatic and Transporter-Mediated Drug-Drug Interactions. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Olivier Fardel, Amélie Moreau, Jennifer Carteret, Claire Denizot, Marc Le Vée, Yannick Parmentier
The Competitive Counterflow Assay for Identifying Drugs Transported by Solute Carriers: Principle, Applications, Challenges/Limits, and Perspectives. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Bo-Yu Chen, Jia-Huan Xu, Qian-Qing Chen, Huan-Xian Wu, Bao-Fang Ou, Zhiwei Zhou, Fei Xu, Shao-Yu Wu, Shui-Lin Xie, Ding-Sheng Wen
Pharmacokinetics and Bioavailability Study of a Novel Smoothened Inhibitor TPB15 for Treatment of Triple-Negative Breast Cancer in Rats by High Performance Liquid Chromatography-Mass Spectrometry. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)
Qi Shen, Wenxuan Chen, Wei Wang, Shuyue Kang, Yuxin Du, Jiaxi Shi, Limei Yao, Wei-Rong Li
Drug Interactions between Traditional Chinese Medicines and Cardiovascular Drugs. European journal of drug metabolism and pharmacokinetics 49 (5) (2024)