Donglu Zhang

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 19

Top Venues

Drug metabolism and disposition: the biological fate of chemicals

Journal of medicinal chemistry

Drug metabolism reviews

Communications medicine

University of Utah (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Utah

United States

PHD :: Chemistry

Publications

Donglu Zhang, Bin Ma, Peter S Dragovich, Li Ma, Shu Chen, Eugene C Chen, Xiaofen Ye, Joyce Liu, Jennifer Pizzano, Elizabeth Bortolon, Emily Chan, Xing Zhang, Yi-Chen Chen, Elizabeth S Levy, Robert L Yauch, S Cyrus Khojasteh, Cornelis E C A Hop
Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs. Communications medicine 4 (1) (2024)
Sungjoon Cho, Lionel Cheruzel, Jingwei Cai, Stephen K Wrigley, Renia T Gemmell, Tetsuo Kokubun, Jonathan C P Steele, Laurent Salphati, Donglu Zhang, S Cyrus Khojasteh
Discovery of Unprecedented Human Stercobilin Conjugates . Drug metabolism and disposition: the biological fate of chemicals (2024)
Donglu Zhang, Bin Ma, Peter S Dragovich, Li Ma, Shu Chen, Eugene C Chen, Xiaofen Ye, Joyce Liu, Jennifer Pizzano, Elizabeth Bortolon, Emily Chan, Xing Zhang, Yi-Chen Chen, Elizabeth S Levy, Robert L Yauch, S Cyrus Khojasteh, Cornelis E C A Hop
Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs. Communications medicine 4 (1) (2024)
Sungjoon Cho, Lionel Cheruzel, Jingwei Cai, Stephen K Wrigley, Renia T Gemmell, Tetsuo Kokubun, Jonathan C P Steele, Laurent Salphati, Donglu Zhang, S Cyrus Khojasteh
Discovery of Unprecedented Human Stercobilin Conjugates. Drug metabolism and disposition: the biological fate of chemicals 52 (9) (2024)
Donglu Zhang, Bin Ma, Peter S Dragovich, Li Ma, Shu Chen, Eugene C Chen, Xiaofen Ye, Joyce Liu, Jennifer Pizzano, Elizabeth Bortolon, Emily Chan, Xing Zhang, Yi-Chen Chen, Elizabeth S Levy, Robert L Yauch, S Cyrus Khojasteh, Cornelis E C A Hop
Tissue distribution and retention drives efficacy of rapidly clearing VHL-based PROTACs. Communications medicine 4 (1) (2024)
Shuai Wang, Upendra A Argikar, Maria Chatzopoulou, Sungjoon Cho, Rachel D Crouch, Deepika Dhaware, Ting-Jia Gu, Carley J S Heck, Kevin M Johnson, Amit S Kalgutkar, Joyce Liu, Bin Ma, Grover P Miller, Jessica A Rowley, Herana Kamal Seneviratne, Donglu Zhang, S Cyrus Khojasteh
Bioactivation and reactivity research advances - 2023 year in review. Drug metabolism reviews (2024)
Shuai Wang, T Eric Ballard, Lisa J Christopher, Robert S Foti, Chungang Gu, S Cyrus Khojasteh, Joyce Liu, Shuguang Ma, Bin Ma, R Scott Obach, Simone Schadt, Zhoupeng Zhang, Donglu Zhang
The Importance of Tracking "Missing" Metabolites: How and Why? Journal of medicinal chemistry (2023)
Ponien Kou, Elizabeth S Levy, An D Nguyen, Donglu Zhang, Shu Chen, Yusi Cui, Xing Zhang, Fabio Broccatelli, Jennifer Pizzano, Jennifer Cantley, Elizabeth Bortolon, Emma Rousseau, Michael Berlin, Peter Dragovich, Vijay Sethuraman
Development of Liposome Systems for Enhancing the PK Properties of Bivalent PROTACs. Pharmaceutics 15 (8) (2023)
Chenghong Zhang, Dian Su, Edna F Choo, Lichuan Liu, Sudheer Bobba, Jamie Jorski, Quynh Ho, Jing Wang, Jane Kenny, S Cyrus Khojasteh, Donglu Zhang
Identification of a Discrete Diglucuronide of GDC-0810 in Human Plasma after Oral Administration . Drug metabolism and disposition: the biological fate of chemicals (2023)
Klarissa D Jackson, Upendra A Argikar, Sungjoon Cho, Rachel D Crouch, James P Driscoll, Carley J S Heck, Lloyd King, Hlaing Holly Maw, Grover P Miller, Herana Kamal Seneviratne, Shuai Wang, Cong Wei, Donglu Zhang, S Cyrus Khojasteh
Bioactivation and reactivity research advances - 2021 year in review. Drug metabolism reviews 54 (3) (2022)
Donglu Zhang, Cong Wei, Cornelis E C A Hop, Matthew R Wright, Ming Hu, Yurong Lai, S Cyrus Khojasteh, W Griff Humphreys
Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs. Journal of medicinal chemistry 64 (11) (2021)
Donglu Zhang, Cong Wei, Cornelis E C A Hop, Matthew R Wright, Ming Hu, Yurong Lai, S Cyrus Khojasteh, W Griff Humphreys
Correction to "Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Molecule Drugs". Journal of medicinal chemistry 64 (21) (2021)
Wei Wang, Mulder Teresa, Jingwei Cai, Chenghong Zhang, Susan Wong, Zhengyin Yan, S Cyrus Khojasteh, Donglu Zhang
Comparative assessment for rat strain differences in metabolic profiles of 14 drugs in Wistar Han and Sprague Dawley hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems 51 (1) (2020)
S Cyrus Khojasteh, James P Driscoll, Klarissa D Jackson, Grover P Miller, Kaushik Mitra, Ivonne M C M Rietjens, Donglu Zhang
Novel advances in biotransformation and bioactivation research-2019 year in review. Drug metabolism reviews 52 (3) (2020)
Donglu Zhang, Peter S Dragovich, Shang-Fan Yu, Yong Ma, Thomas H Pillow, Jack D Sadowsky, Dian Su, Wei Wang, Andrew Polson, S Cyrus Khojasteh, Cornelis E C A Hop
Exposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to Tissues. Drug metabolism and disposition: the biological fate of chemicals 47 (10) (2019)
Donglu Zhang, Hoa Le, Josefa Dela Cruz-Chuh, Sudheer Bobba, Jun Guo, Leanna Staben, Chenghong Zhang, Yong Ma, Katherine R Kozak, Gail D Lewis Phillips, Breanna S Vollmar, Jack D Sadowsky, Richard Vandlen, BinQing Wei, Dian Su, Peter Fan, Peter S Dragovich, S Cyrus Khojasteh, Cornelis E C A Hop, Thomas H Pillow
Immolation of p-Aminobenzyl Ether Linker and Payload Potency and Stability Determine the Cell-Killing Activity of Antibody-Drug Conjugates with Phenol-Containing Payloads. Bioconjugate chemistry 29 (2) (2018)
Zhonghua Pei, Chunjiao Chen, Jinhua Chen, Josefa Dela Cruz-Chuh, Reginald Delarosa, Yuzhong Deng, Aimee Fourie-O'Donohue, Isabel Figueroa, Jun Guo, Weiwei Jin, S Cyrus Khojasteh, Katherine R Kozak, Brandon Latifi, James Lee, Guangmin Li, Eva Lin, Liling Liu, Jiawei Lu, Scott Martin, Carl Ng, Trung Nguyen, Rachana Ohri, Gail Lewis Phillips, Thomas H Pillow, Rebecca K Rowntree, Nicola J Stagg, David Stokoe, Sheila Ulufatu, Vishal A Verma, John Wai, Jing Wang, Keyang Xu, Zijin Xu, Hui Yao, Shang-Fan Yu, Donglu Zhang, Peter S Dragovich
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates. Molecular pharmaceutics 15 (9) (2018)
Yong Ma, Yue Fu, S Cyrus Khojasteh, Deepak Dalvie, Donglu Zhang
Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8). Journal of medicinal chemistry 60 (21) (2017)
Jack D Sadowsky, Thomas H Pillow, Jinhua Chen, Fang Fan, Changrong He, Yanli Wang, Gang Yan, Hui Yao, Zijin Xu, Shanique Martin, Donglu Zhang, Phillip Chu, Josefa Dela Cruz-Chuh, Aimee O'Donohue, Guangmin Li, Geoffrey Del Rosario, Jintang He, Luna Liu, Carl Ng, Dian Su, Gail D Lewis Phillips, Katherine R Kozak, Shang-Fan Yu, Keyang Xu, Douglas Leipold, John Wai
Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein- and Peptide-Payload Conjugates: Application to THIOMAB Antibody-Drug Conjugates. Bioconjugate chemistry 28 (8) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Donglu Zhang