Duane D Miller

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 38

Top Topics

Structural Basis

Prostate Cancer

Radical Prostatectomy

Top Venues

Journal of medicinal chemistry

Proceedings of the National Academy of Sciences of the United States of America

ACS pharmacology & translational science

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Satyanarayana Pochampally, Kelli L Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Keyur R Parmar, Hyunseo Park, Bernd Meibohm, Stephen W White, Wei Li, Duane D Miller
Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. ACS pharmacology & translational science 6 (4) (2023)
Satyanarayana Pochampally, Kelli L Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Keyur R Parmar, Hyunseo Park, Bernd Meibohm, Stephen W White, Wei Li, Duane D Miller
Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. ACS pharmacology & translational science 6 (4) (2023)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 66 (5) (2023)
Satyanarayana Pochampally, Kelli L Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Keyur R Parmar, Hyunseo Park, Bernd Meibohm, Stephen W White, Wei Li, Duane D Miller
Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. ACS pharmacology & translational science 6 (4) (2023)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 66 (5) (2023)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 66 (5) (2023)
Satyanarayana Pochampally, Kelli L Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Keyur R Parmar, Hyunseo Park, Bernd Meibohm, Stephen W White, Wei Li, Duane D Miller
Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo. ACS pharmacology & translational science 6 (4) (2023)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 66 (5) (2023)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry (2023)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Shanshan Deng, Raisa I Krutilina, Kelli L Hartman, Hao Chen, Deanna N Parke, Rui Wang, Sasha H Shafikhani, Dejian Ma, Pradeep B Lukka, Bernd Meibohm, Tiffany N Seagroves, Duane D Miller, Wei Li
Colchicine-Binding Site Agent CH-2-77 as a Potent Tubulin Inhibitor Suppressing Triple-Negative Breast Cancer. Molecular cancer therapeutics 21 (7) (2022)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Raisa I Krutilina, Kelli L Hartman, Damilola Oluwalana, Hilaire C Playa, Deanna N Parke, Hao Chen, Duane D Miller, Wei Li, Tiffany N Seagroves
Sabizabulin, a Potent Orally Bioavailable Colchicine Binding Site Agent, Suppresses HER2+ Breast Cancer and Metastasis. Cancers 14 (21) (2022)
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Kirsten L Young, Daniel L Johnson, Vera Bocharova, Weidong Zhou, Abhinav K Jain, Emanuel F Petricoin, Zheng Yin, Lawrence M Pfeffer, Duane D Miller, Ramesh Narayanan
Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer. Proceedings of the National Academy of Sciences of the United States of America 120 (1) (2022)
Chuanhe Yang, Yinan Wang, Michelle M Sims, Yali He, Duane D Miller, Lawrence M Pfeffer
Targeting the Bromodomain of BRG-1/BRM Subunit of the SWI/SNF Complex Increases the Anticancer Activity of Temozolomide in Glioblastoma. Pharmaceuticals (Basel, Switzerland) 14 (9) (2021)
Sicheng Zhang, Duane D Miller, Wei Li
Non-Musculoskeletal Benefits of Vitamin D beyond the Musculoskeletal System. International journal of molecular sciences 22 (4) (2021)
Souvik Banerjee, Shalini Yadav, Sourav Banerjee, Sayo O Fakayode, Jyothi Parvathareddy, Walter Reichard, Surekha Surendranathan, Foyez Mahmud, Ryan Whatcott, Joshua Thammathong, Bernd Meibohm, Duane D Miller, Colleen Beth Jonsson, Kshatresh Dutta Dubey
Drug Repurposing to Identify Nilotinib as a Potential SARS-CoV-2 Main Protease Inhibitor: Insights from a Computational and In Vitro Study. Journal of chemical information and modeling 61 (11) (2021)
Monica L Brown Lobbins, Andrzej T Słominski, Karen A Hasty, Sicheng Zhang, Duane D Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Robert Charles Tuckey, Imara-Safi O Scott, Linda K Myers, Arnold E Postlethwaite
Modulation by 17,20S(OH) 2 pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis. International journal of molecular sciences 23 (1) (2021)
Yali He, Dong-Jin Hwang, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 64 (15) (2021)
Monica L Brown Lobbins, Imara-Safi O Scott, Andrzej T Słominski, Karen A Hasty, Sicheng Zhang, Duane D Miller, Wei Li, Tae-Kang Kim, Zorica Janjetovic, Tejesh S Patel, Linda K Myers, Arnold E Postlethwaite
17,20S(OH)2pD Can Prevent the Development of Skin Fibrosis in the Bleomycin-Induced Scleroderma Mouse Model. International journal of molecular sciences 22 (16) (2021)
Souvik Banerjee, Foyez Mahmud, Shanshan Deng, Lingling Ma, Mi-Kyung Yun, Sayo O Fakayode, Kinsie E Arnst, Lei Yang, Hao Chen, Zhongzhi Wu, Pradeep B Lukka, Keyur Parmar, Bernd Meibohm, Stephen W White, Yu-Xi Wang, Wei Li, Duane D Miller
X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor. Journal of medicinal chemistry 64 (17) (2021)
Wen Shuai, Guan Wang, Yiwen Zhang, Faqian Bu, Sicheng Zhang, Duane D Miller, Wei Li, Liang Ouyang, Yu-Xi Wang
Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy. Journal of medicinal chemistry 64 (12) (2021)
Hao Chen, Shanshan Deng, Najah Albadari, Mi-Kyung Yun, Sicheng Zhang, Yong Li, Dejian Ma, Deanna N Parke, Lei Yang, Tiffany N Seagroves, Stephen W White, Duane D Miller, Wei Li
Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents. Journal of medicinal chemistry 64 (16) (2021)
Michael L Mohler, Arunima Sikdar, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Duane D Miller, Ramesh Narayanan
An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer. International journal of molecular sciences 22 (4) (2021)
Yali He, Dong-Jin Hwang, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Ramesh Narayanan, Duane D Miller
Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer. Journal of medicinal chemistry 63 (21) (2020)
Hao Chen, Shanshan Deng, Yuxi Wang, Najah Albadari, Gyanendra Kumar, Dejian Ma, Weimin Li, Stephen W White, Duane D Miller, Wei Li
Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. Journal of medicinal chemistry 63 (2) (2020)
Shanshan Deng, Raisa I Krutilina, Qinghui Wang, Zongtao Lin, Deanna N Parke, Hilaire C Playa, Hao Chen, Duane D Miller, Tiffany N Seagroves, Wei Li
An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance. Molecular cancer therapeutics 19 (2) (2019)
Kinsie E Arnst, Souvik Banerjee, Yuxi Wang, Hao Chen, Yong Li, Lei Yang, Weimin Li, Duane D Miller, Wei Li
X-ray Crystal Structure Guided Discovery and Antitumor Efficacy of Dihydroquinoxalinone as Potent Tubulin Polymerization Inhibitors. ACS chemical biology 14 (12) (2019)
Qinghui Wang, Kinsie E Arnst, Yuxi Wang, Gyanendra Kumar, Dejian Ma, Stephen W White, Duane D Miller, Weimin Li, Wei Li
Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. Journal of medicinal chemistry 62 (14) (2019)
Kinsie E Arnst, Souvik Banerjee, Hao Chen, Shanshan Deng, Dong-Jin Hwang, Wei Li, Duane D Miller
Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy. Medicinal research reviews 39 (4) (2019)
Dmitry N Voylov, Vera Bocharova, Nickolay V Lavrik, Ivan V Vlassiouk, Georgios Polizos, Alexei Volodin, Yury M Shulga, Alexander Kisliuk, Thirumagal Thiyagarajan, Duane D Miller, Ramesh Narayanan, Bobby G Sumpter, Alexei P Sokolov
Noncontact tip-enhanced Raman spectroscopy for nanomaterials and biomedical applications. Nanoscale advances 1 (9) (2019)
Souvik Banerjee, Kinsie E Arnst, Yuxi Wang, Gyanendra Kumar, Shanshan Deng, Lei Yang, Guo-Bo Li, Jinliang Yang, Stephen W White, Wei Li, Duane D Miller
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. Journal of medicinal chemistry 61 (4) (2018)
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Michael L Mohler, Thirumagal Thiyagarajan, Iain J McEwan, Ramesh Narayanan, Duane D Miller
New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity. Journal of medicinal chemistry 62 (2) (2018)
Qinghui Wang, Kinsie E Arnst, Yuxi Wang, Gyanendra Kumar, Dejian Ma, Hao Chen, Zhongzhi Wu, Jinliang Yang, Stephen W White, Duane D Miller, Wei Li
Structural Modification of the 3,4,5-Trimethoxyphenyl Moiety in the Tubulin Inhibitor VERU-111 Leads to Improved Antiproliferative Activities. Journal of medicinal chemistry 61 (17) (2018)
Souvik Banerjee, Derek D Norman, Sue Chin Lee, Abby L Parrill, Truc Chi T Pham, Daniel L Baker, Gabor J Tigyi, Duane D Miller
Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. Journal of medicinal chemistry 60 (4) (2017)