Yu-Xi Wang (Yuxi Wang)

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 33

Top Topics

Tyrosine Kinase

Crystal Structure

Top Venues

Journal of medicinal chemistry

Journal of agricultural and food chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Aoxue Wang, Wen Shuai, Chengyong Wu, Junping Pei, Panpan Yang, Xin Wang, Shutong Li, Jiaxi Liu, Yu-Xi Wang, Guan Wang, Liang Ouyang
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR L858R/T790M /ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers. Journal of medicinal chemistry (2024)
Yisha Huang, Tong Liu, Qi Huang, Yu-Xi Wang
From Organ-on-a-Chip to Human-on-a-Chip: A Review of Research Progress and Latest Applications. ACS sensors (2024)
Yisha Huang, Tong Liu, Qi Huang, Yu-Xi Wang
From Organ-on-a-Chip to Human-on-a-Chip: A Review of Research Progress and Latest Applications. ACS sensors 9 (7) (2024)
Aoxue Wang, Wen Shuai, Chengyong Wu, Junping Pei, Panpan Yang, Xin Wang, Shutong Li, Jiaxi Liu, Yu-Xi Wang, Guan Wang, Liang Ouyang
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR L858R/T790M /ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers. Journal of medicinal chemistry 67 (4) (2024)
Xinqi Liang, Ruixian Chen, Chengdi Wang, Yu-Xi Wang, Jifa Zhang
Targeting HSP90 for Cancer Therapy: Current Progress and Emerging Prospects. Journal of medicinal chemistry (2024)
Aoxue Wang, Wen Shuai, Chengyong Wu, Junping Pei, Panpan Yang, Xin Wang, Shutong Li, Jiaxi Liu, Yu-Xi Wang, Guan Wang, Liang Ouyang
Design, Synthesis, and Biological Evaluation of Dual Inhibitors of EGFR L858R/T790M /ACK1 to Overcome Osimertinib Resistance in Nonsmall Cell Lung Cancers. Journal of medicinal chemistry 67 (4) (2024)
Chunlin Qian, Xiaoxue Li, Jifa Zhang, Yu-Xi Wang
Small Molecular Inhibitors That Target ATM for Drug Discovery: Current Research and Potential Prospective. Journal of medicinal chemistry (2024)
Lun Tan, Chengyong Wu, Jifa Zhang, Quanwei Yu, Xiye Wang, Lele Zhang, Meiyi Ge, Zhijia Wang, Liang Ouyang, Yu-Xi Wang
Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site. Journal of medicinal chemistry (2023)
Lun Tan, Chengyong Wu, Jifa Zhang, Quanwei Yu, Xiye Wang, Lele Zhang, Meiyi Ge, Zhijia Wang, Liang Ouyang, Yu-Xi Wang
Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site. Journal of medicinal chemistry 66 (5) (2023)
Yijia Chen, Yu-Xi Wang, Jiaxing Wang, Zhilan Zhou, Shu Cao, Jifa Zhang
Strategies of Targeting CK2 in Drug Discovery: Challenges, Opportunities, and Emerging Prospects. Journal of medicinal chemistry 66 (4) (2023)
Lichao Tang, Jiyuan Yang, Yu-Xi Wang, Ruijie Deng
Recent Advances in Cardiovascular Disease Biosensors and Monitoring Technologies. ACS sensors (2023)
Junping Pei, Guan Wang, Aoxue Wang, Chengyong Wu, Xiaoli Pan, Wen Shuai, Faqian Bu, Yumeng Zhu, Yu-Xi Wang, Liang Ouyang, Weimin Li
Design, Synthesis, and Antitumor Activity of Potent and Selective EGFR L858R/T790M Inhibitors and Identification of a Combination Therapy to Overcome Acquired Resistance in Models of Non-small-cell Lung Cancer. Journal of medicinal chemistry (2023)
Lun Tan, Chengyong Wu, Jifa Zhang, Quanwei Yu, Xiye Wang, Lele Zhang, Meiyi Ge, Zhijia Wang, Liang Ouyang, Yu-Xi Wang
Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site. Journal of medicinal chemistry 66 (5) (2023)
Yijia Chen, Yu-Xi Wang, Jiaxing Wang, Zhilan Zhou, Shu Cao, Jifa Zhang
Strategies of Targeting CK2 in Drug Discovery: Challenges, Opportunities, and Emerging Prospects. Journal of medicinal chemistry (2023)
Yijia Chen, Yu-Xi Wang, Jiaxing Wang, Zhilan Zhou, Shu Cao, Jifa Zhang
Strategies of Targeting CK2 in Drug Discovery: Challenges, Opportunities, and Emerging Prospects. Journal of medicinal chemistry 66 (4) (2023)
Yichang Ren, Yu-Xi Wang, Jin Liu, Ting Liu, Lin Yuan, Chengyong Wu, Zichao Yang, Jianjun Chen
X-ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma. Journal of medicinal chemistry (2023)
Yijia Chen, Yu-Xi Wang, Jiaxing Wang, Zhilan Zhou, Shu Cao, Jifa Zhang
Strategies of Targeting CK2 in Drug Discovery: Challenges, Opportunities, and Emerging Prospects. Journal of medicinal chemistry 66 (4) (2023)
Jiayu Wang, Jifa Zhang, Jiaxing Wang, Xinyue Hu, Liang Ouyang, Yu-Xi Wang
Small-Molecule Modulators Targeting Toll-like Receptors for Potential Anticancer Therapeutics. Journal of medicinal chemistry (2023)
Lun Tan, Chengyong Wu, Jifa Zhang, Quanwei Yu, Xiye Wang, Lele Zhang, Meiyi Ge, Zhijia Wang, Liang Ouyang, Yu-Xi Wang
Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X-ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site. Journal of medicinal chemistry 66 (5) (2023)
Lichao Tang, Jiyuan Yang, Yu-Xi Wang, Ruijie Deng
Recent Advances in Cardiovascular Disease Biosensors and Monitoring Technologies. ACS sensors 8 (3) (2023)
Yingxu Fang, Jiaxing Wang, Min Zhao, Qinwen Zheng, Changyu Ren, Yu-Xi Wang, Jifa Zhang
Progress and Challenges in Targeted Protein Degradation for Neurodegenerative Disease Therapy. Journal of medicinal chemistry 65 (17) (2022)
Ting Xue, Ying Lu, Hao Yang, Xinyue Hu, Kaixiang Zhang, Yao Ren, Chengyong Wu, Xuhan Xia, Ruijie Deng, Yu-Xi Wang
Isothermal RNA Amplification for the Detection of Viable Pathogenic Bacteria to Estimate the Salmonella Virulence for Causing Enteritis. Journal of agricultural and food chemistry 70 (5) (2022)
Lun Tan, Jifa Zhang, Yu-Xi Wang, Xiye Wang, Yanyan Wang, Zhixiong Zhang, Wen Shuai, Guan Wang, Juncheng Chen, Chengdi Wang, Liang Ouyang, Wei-Min Li
Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy. Journal of medicinal chemistry 65 (7) (2022)
Juncheng Chen, Pan Tang, Yu-Xi Wang, Jiaxing Wang, Chengcan Yang, Yang Li, Gaoxia Yang, Fengbo Wu, Jifa Zhang, Liang Ouyang
Targeting Bromodomain-Selective Inhibitors of BET Proteins in Drug Discovery and Development. Journal of medicinal chemistry 65 (7) (2022)
Jifa Zhang, Chengcan Yang, Pan Tang, Juncheng Chen, Dan Zhang, Yang Li, Gaoxia Yang, Yun Liu, Yiwen Zhang, Yu-Xi Wang, Jie Liu, Liang Ouyang
Discovery of 4-Hydroxyquinazoline Derivatives as Small Molecular BET/PARP1 Inhibitors That Induce Defective Homologous Recombination and Lead to Synthetic Lethality for Triple-Negative Breast Cancer Therapy. Journal of medicinal chemistry 65 (9) (2022)
Jifa Zhang, Lele Zhang, Jiaxing Wang, Liang Ouyang, Yu-Xi Wang
Polo-like Kinase 1 Inhibitors in Human Cancer Therapy: Development and Therapeutic Potential. Journal of medicinal chemistry 65 (15) (2022)
Weirong Lai, Shengyan Zhao, Qinhuai Lai, Wei Zhou, Mengdan Wu, Xiaohua Jiang, Xin Wang, Yujia Peng, Xian Wei, Liang Ouyang, Lantu Gou, Hao Chen, Yu-Xi Wang, Jinliang Yang
Design, Synthesis, and Bioevaluation of a Novel Hybrid Molecular Pyrrolobenzodiazepine-Anthracenecarboxyimide as a Payload for Antibody-Drug Conjugate. Journal of medicinal chemistry 65 (17) (2022)
Kunyu Shi, Jifa Zhang, Enda Zhou, Jiaxing Wang, Yu-Xi Wang
Small-Molecule Receptor-Interacting Protein 1 (RIP1) Inhibitors as Therapeutic Agents for Multifaceted Diseases: Current Medicinal Chemistry Insights and Emerging Opportunities. Journal of medicinal chemistry 65 (22) (2022)
Jia-Hong Lei, Ling-Ling Ma, Jing-Hong Xian, Hai Chen, Jian-Jian Zhou, Hao Chen, Qian Lei, Yu-Yan Li, Yan-Yan Wang, Yu-Xi Wang
Structural insights into targeting of the colchicine binding site by ELR510444 and parbendazole to achieve rational drug design. RSC advances 11 (31) (2021)
Aoxue Wang, Junping Pei, Wen Shuai, Congcong Lin, Lu Feng, Yu-Xi Wang, Feng Lin, Liang Ouyang, Guan Wang
Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of Cancers. Journal of medicinal chemistry 64 (22) (2021)
Souvik Banerjee, Foyez Mahmud, Shanshan Deng, Lingling Ma, Mi-Kyung Yun, Sayo O Fakayode, Kinsie E Arnst, Lei Yang, Hao Chen, Zhongzhi Wu, Pradeep B Lukka, Keyur Parmar, Bernd Meibohm, Stephen W White, Yu-Xi Wang, Wei Li, Duane D Miller
X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor. Journal of medicinal chemistry 64 (17) (2021)
Ting Xue, Weikun Wu, Ning Guo, Chengyong Wu, Jian Huang, Lipeng Lai, Hong Liu, Yalun Li, Tianyuan Wang, Yu-Xi Wang
Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay. RSC advances 11 (24) (2021)
Wen Shuai, Guan Wang, Yiwen Zhang, Faqian Bu, Sicheng Zhang, Duane D Miller, Wei Li, Liang Ouyang, Yu-Xi Wang
Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy. Journal of medicinal chemistry 64 (12) (2021)