Guo-Bo Li

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 31

Top Topics

Molecular Docking

Antimicrobial Resistance

Klebsiella Pneumoniae

Top Venues

Journal of medicinal chemistry

Signal transduction and targeted therapy

The Journal of organic chemistry

Chemical communications (Cambridge, England)

This page only lists publications with an associated author ORCID identifier.

Publications

Jun Mou, Xiang-Li Ning, Xin-Yue Wang, Shu-Yan Hou, Fan-Bo Meng, Cong Zhou, Jing-Wei Wu, Chunyan Li, Tao Jia, Xiaoai Wu, Yong Wu, Yongping Chen, Guo-Bo Li
X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model. Journal of medicinal chemistry 67 (11) (2024)
Yu-Hang Yan, Liu-Liu Wei, Jing-Wei Wu, Si-Qi Wei, Ying-Ying Jiang, Jun-Lin Yu, Ling-Ling Yang, Guo-Bo Li
Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform. Journal of medicinal chemistry 67 (16) (2024)
Yu-Hang Yan, Liu-Liu Wei, Jing-Wei Wu, Si-Qi Wei, Ying-Ying Jiang, Jun-Lin Yu, Ling-Ling Yang, Guo-Bo Li
Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform. Journal of medicinal chemistry 67 (16) (2024)
Yu-Hang Yan, Liu-Liu Wei, Jing-Wei Wu, Si-Qi Wei, Ying-Ying Jiang, Jun-Lin Yu, Ling-Ling Yang, Guo-Bo Li
Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform. Journal of medicinal chemistry (2024)
Wen-Jing Wang, Xiang-Min Dong, Guo-Bo Li
Macrocyclic peptides: up-and-coming weapons to combat antimicrobial resistance. Signal transduction and targeted therapy 9 (1) (2024)
Wen-Jing Wang, Xiang-Min Dong, Guo-Bo Li
Macrocyclic peptides: up-and-coming weapons to combat antimicrobial resistance. Signal transduction and targeted therapy 9 (1) (2024)
Jun Mou, Xiang-Li Ning, Xin-Yue Wang, Shu-Yan Hou, Fan-Bo Meng, Cong Zhou, Jing-Wei Wu, Chunyan Li, Tao Jia, Xiaoai Wu, Yong Wu, Yongping Chen, Guo-Bo Li
X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model. Journal of medicinal chemistry (2024)
Wen-Jing Wang, Xiang-Min Dong, Guo-Bo Li
Macrocyclic peptides: up-and-coming weapons to combat antimicrobial resistance. Signal transduction and targeted therapy 9 (1) (2024)
Hong-Jiao He, Rui-Qi Wang, Lin-Xi Wan, Li-Yan Zhou, Hong-Yan Li, Guo-Bo Li, You-Cai Xiao, Xiangtao Chen
Organocatalytic Asymmetric Morita-Baylis-Hillman Reaction of Isatins with Vinyl Sulfones. The Journal of organic chemistry (2023)
Yu-Hang Yan, Ting-Ting Zhang, Rong Li, Si-Yao Wang, Liu-Liu Wei, Xin-Yue Wang, Kai-Rong Zhu, Shan-Rui Li, Guo-Qing Liang, Zeng-Bao Yang, Ling-Ling Yang, Shangshang Qin, Guo-Bo Li
Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. Journal of medicinal chemistry (2023)
Luohe Mou, Lina Yang, Shuyan Hou, Bo Wang, Xinyue Wang, Lei Hu, Jianlin Deng, Jiayu Liu, Xi Chen, Yingying Jiang, Weifeng Zhang, Pengcheng Lei, Lijiao Wang, Rong Li, Ping Fu, Guo-Bo Li, Liang Ma, Ling-Ling Yang
Structure-Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney Injury. Journal of medicinal chemistry (2023)
Hong-Jiao He, Rui-Qi Wang, Lin-Xi Wan, Li-Yan Zhou, Hong-Yan Li, Guo-Bo Li, You-Cai Xiao, Xiangtao Chen
Organocatalytic Asymmetric Morita-Baylis-Hillman Reaction of Isatins with Vinyl Sulfones. The Journal of organic chemistry 88 (6) (2023)
Gen Li, Qing-Qing Dai, Guo-Bo Li
MeCOM: A Method for Comparing Three-Dimensional Metalloenzyme Active Sites. Journal of chemical information and modeling 62 (3) (2022)
Guan-Jun Dong, Jiahui Zuo, Junlin Yu, Jiale Xu, Ge Gao, Guo-Bo Li, Wen Zhao, Bin Yu
Structure-Based Design of the Indole-Substituted Triazolopyrimidines as New EED-H3K27me3 Inhibitors for the Treatment of Lymphoma. Journal of medicinal chemistry (2022)
Guan-Jun Dong, Jiahui Zuo, Junlin Yu, Jiale Xu, Ge Gao, Guo-Bo Li, Wen Zhao, Bin Yu
Structure-Based Design of the Indole-Substituted Triazolopyrimidines as New EED-H3K27me3 Inhibitors for the Treatment of Lymphoma. Journal of medicinal chemistry 66 (1) (2022)
Guan-Jun Dong, Jiahui Zuo, Junlin Yu, Jiale Xu, Ge Gao, Guo-Bo Li, Wen Zhao, Bin Yu
Structure-Based Design of the Indole-Substituted Triazolopyrimidines as New EED-H3K27me3 Inhibitors for the Treatment of Lymphoma. Journal of medicinal chemistry 66 (1) (2022)
Jun-Lin Yu, Song Wu, Cong Zhou, Qing-Qing Dai, Christopher J Schofield, Guo-Bo Li
MeDBA: the Metalloenzyme Data Bank and Analysis platform. Nucleic acids research (2022)
Guan-Jun Dong, Jiahui Zuo, Junlin Yu, Jiale Xu, Ge Gao, Guo-Bo Li, Wen Zhao, Bin Yu
Structure-Based Design of the Indole-Substituted Triazolopyrimidines as New EED-H3K27me3 Inhibitors for the Treatment of Lymphoma. Journal of medicinal chemistry 66 (1) (2022)
Shuo Yuan, Bo Wang, Qing-Qing Dai, Xiao-Nan Zhang, Jing-Ya Zhang, Jia-Hui Zuo, Hui Liu, Zhe-Sheng Chen, Guo-Bo Li, Shaomeng Wang, Hong-Min Liu, Bin Yu
Discovery of New 4-Indolyl Quinazoline Derivatives as Highly Potent and Orally Bioavailable P-Glycoprotein Inhibitors. Journal of medicinal chemistry 64 (19) (2021)
You-Cai Xiao, Xiao-Pan Chen, Ji Deng, Yu-Hang Yan, Kai-Rong Zhu, Gen Li, Jun-Lin Yu, Jürgen Brem, Fener Chen, Christopher J Schofield, Guo-Bo Li
Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance. Chemical communications (Cambridge, England) 57 (62) (2021)
Xiang-Li Ning, Yu-Zhi Li, Cui Huo, Ji Deng, Cheng Gao, Kai-Rong Zhu, Miao Wang, Yu-Xiang Wu, Jun-Lin Yu, Ya-Li Ren, Zong-Yuan Luo, Gen Li, Yang Chen, Si-Yao Wang, Cheng Peng, Ling-Ling Yang, Zhou-Yu Wang, Yong Wu, Shan Qian, Guo-Bo Li
X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease. Journal of medicinal chemistry 64 (12) (2021)
You-Cai Xiao, Jun-Lin Yu, Qing-Qing Dai, Gen Li, Guo-Bo Li
Targeting Metalloenzymes by Boron-Containing Metal-Binding Pharmacophores. Journal of medicinal chemistry (2021)
Yu-Hang Yan, Gen Li, Guo-Bo Li
Principles and current strategies targeting metallo-β-lactamase mediated antibacterial resistance. Medicinal research reviews 40 (5) (2020)
Yuesen Shi, Huimin Xing, Tianle Huang, Xuexin Liu, Jian Chen, Xiaoyu Guo, Guo-Bo Li, Yong Wu
Divergent C-H activation synthesis of chalcones, quinolones and indoles. Chemical communications (Cambridge, England) 56 (10) (2020)
Yu-Hang Yan, Jian Chen, Zhen Zhan, Zhu-Jun Yu, Gen Li, Li Guo, Guo-Bo Li, Yong Wu, Yongxiang Zheng
Discovery of mercaptopropanamide-substituted aryl tetrazoles as new broad-spectrum metallo-β-lactamase inhibitors. RSC advances 10 (52) (2020)
Yao Hu, Ting Wang, Yanzhao Liu, Ruifang Nie, Ninghong Yang, Qiantao Wang, Guo-Bo Li, Yong Wu
Practical Synthesis of Benzimidazo[1,2-a]quinolines via Rh(III)-Catalyzed C-H Activation Cascade Reaction from Imidamides and Anthranils. Organic letters 22 (2) (2019)
Yao-Ling Wang, Sha Liu, Zhu-Jun Yu, Yuan Lei, Meng-Yi Huang, Yu-Hang Yan, Qiang Ma, Yang Zheng, Hui Deng, Ying Sun, Chengyong Wu, Yamei Yu, Qiang Chen, Zhenling Wang, Yong Wu, Guo-Bo Li
Structure-Based Development of (1-(3'-Mercaptopropanamido)methyl)boronic Acid Derived Broad-Spectrum, Dual-Action Inhibitors of Metallo- and Serine-β-lactamases. Journal of medicinal chemistry 62 (15) (2019)
Souvik Banerjee, Kinsie E Arnst, Yuxi Wang, Gyanendra Kumar, Shanshan Deng, Lei Yang, Guo-Bo Li, Jinliang Yang, Stephen W White, Wei Li, Duane D Miller
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. Journal of medicinal chemistry 61 (4) (2018)
Ling-Ling Yang, Wei Xu, Jie Yan, Hui-Lin Su, Chen Yuan, Chao Li, Xing Zhang, Zhu-Jun Yu, Yu-Hang Yan, Yamei Yu, Qiang Chen, Zhouyu Wang, Lin Li, Shan Qian, Guo-Bo Li
Crystallographic and SAR analyses reveal the high requirements needed to selectively and potently inhibit SIRT2 deacetylase and decanoylase. MedChemComm 10 (1) (2018)
Guo-Bo Li, Zhu-Jun Yu, Sha Liu, Lu-Yi Huang, Ling-Ling Yang, Christopher T Lohans, Sheng-Yong Yang
IFPTarget: A Customized Virtual Target Identification Method Based on Protein-Ligand Interaction Fingerprinting Analyses. Journal of chemical information and modeling 57 (7) (2017)
Sha Liu, Sen Ji, Zhu-Jun Yu, Hua-Li Wang, Xu Cheng, Wei-Jian Li, Li Jing, Yamei Yu, Qiang Chen, Ling-Ling Yang, Guo-Bo Li, Yong Wu
Structure-based discovery of new selective small-molecule sirtuin 5 inhibitors. Chemical biology & drug design 91 (1) (2017)