Elgene Lim

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 35

Top Topics

Positive Breast Cancer

Clostridium Difficile

Endoplasmic Reticulum

Estrogen Receptor

Top Venues

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical cancer research : an official journal of the American Association for Cancer Research

Growth factors (Chur, Switzerland)

This page only lists publications with an associated author ORCID identifier.

Publications

Emma J Thompson, Samantha Escarbe, Denis Tvorogov, Gelareh Farshid, Philip A Gregory, Yeesim Khew-Goodall, Stephen Madden, Wendy V Ingman, Geoffrey J Lindeman, Elgene Lim, Angel F Lopez, Claudine S Bonder
Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth factors (Chur, Switzerland) 42 (2) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Miguel Martin, Elgene Lim, Mariana Chavez Mac Gregor, Aditya Bardia, Jiong Wu, Qingyuan Zhang, Zbigniew Nowecki, Felipe José Silva Melo Cruz, Rustem Safin, Sung-Bae Kim, Christian Schem, Alberto J Montero, Sarah Khan, Reeti Bandyopadhyay, Heather M Moore, Mahesh Shivhare, Monika Patre, Jorge Martinalbo, Laura Roncoroni, Pablo Diego Pérez-Moreno, Joo Hyuk Sohn, null null
Giredestrant for Estrogen Receptor-Positive, HER2-Negative, Previously Treated Advanced Breast Cancer: Results From the Randomized, Phase II acelERA Breast Cancer Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Miguel Martin, Elgene Lim, Mariana Chavez Mac Gregor, Aditya Bardia, Jiong Wu, Qingyuan Zhang, Zbigniew Nowecki, Felipe José Silva Melo Cruz, Rustem Safin, Sung-Bae Kim, Christian Schem, Alberto J Montero, Sarah Khan, Reeti Bandyopadhyay, Heather M Moore, Mahesh Shivhare, Monika Patre, Jorge Martinalbo, Laura Roncoroni, Pablo Diego Pérez-Moreno, Joo Hyuk Sohn, null null
Giredestrant for Estrogen Receptor-Positive, HER2-Negative, Previously Treated Advanced Breast Cancer: Results From the Randomized, Phase II acelERA Breast Cancer Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Miguel Martin, Elgene Lim, Mariana Chavez Mac Gregor, Aditya Bardia, Jiong Wu, Qingyuan Zhang, Zbigniew Nowecki, Felipe José Silva Melo Cruz, Rustem Safin, Sung-Bae Kim, Christian Schem, Alberto J Montero, Sarah Khan, Reeti Bandyopadhyay, Heather M Moore, Mahesh Shivhare, Monika Patre, Jorge Martinalbo, Laura Roncoroni, Pablo Diego Pérez-Moreno, Joo Hyuk Sohn, null null
Giredestrant for Estrogen Receptor-Positive, HER2-Negative, Previously Treated Advanced Breast Cancer: Results From the Randomized, Phase II acelERA Breast Cancer Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Emma J Thompson, Samantha Escarbe, Denis Tvorogov, Gelareh Farshid, Philip A Gregory, Yeesim Khew-Goodall, Stephen Madden, Wendy V Ingman, Geoffrey J Lindeman, Elgene Lim, Angel F Lopez, Claudine S Bonder
Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth factors (Chur, Switzerland) (2024)
Emma J Thompson, Samantha Escarbe, Denis Tvorogov, Gelareh Farshid, Philip A Gregory, Yeesim Khew-Goodall, Stephen Madden, Wendy V Ingman, Geoffrey J Lindeman, Elgene Lim, Angel F Lopez, Claudine S Bonder
Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth factors (Chur, Switzerland) 42 (2) (2024)
Emma J Thompson, Samantha Escarbe, Denis Tvorogov, Gelareh Farshid, Philip A Gregory, Yeesim Khew-Goodall, Stephen Madden, Wendy V Ingman, Geoffrey J Lindeman, Elgene Lim, Angel F Lopez, Claudine S Bonder
Interleukin-3 production by basal-like breast cancer cells is associated with poor prognosis. Growth factors (Chur, Switzerland) 42 (2) (2024)
Miguel Martin, Elgene Lim, Mariana Chavez Mac Gregor, Aditya Bardia, Jiong Wu, Qingyuan Zhang, Zbigniew Nowecki, Felipe José Silva Melo Cruz, Rustem Safin, Sung-Bae Kim, Christian Schem, Alberto J Montero, Sarah Khan, Reeti Bandyopadhyay, Heather M Moore, Mahesh Shivhare, Monika Patre, Jorge Martinalbo, Laura Roncoroni, Pablo Diego Pérez-Moreno, Joo Hyuk Sohn, null null
Giredestrant for Estrogen Receptor-Positive, HER2-Negative, Previously Treated Advanced Breast Cancer: Results From the Randomized, Phase II acelERA Breast Cancer Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 42 (18) (2024)
Komal L Jhaveri, Elgene Lim, Rinath M Jeselsohn, Cynthia X Ma, Erika Paige Hamilton, Cynthia Osborne, Manali Bhave, Peter A Kaufman, J Thaddeus Beck, Luis Manso Sanchez, Ritesh Parajuli, Hwei-Chung Wang, Jessica J Tao, Seock-Ah Im, Kathleen K Harnden, Kan Yonemori, Ajay Dhakal, Patrick Neven, Philippe Aftimos, Jean-Yves Pierga, Yen-Shen Lu, Timothy Larson, Yolanda Jerez, Kostandinos Sideras, Joo Hyuk Sohn, Sung-Bae Kim, Cristina Saura, Aditya Bardia, Sarah L Sammons, Francesca Bacchion, Yujia Li, Eunice Yuen, Shawn T Estrem, Vanessa Rodrik-Outmezguine, Bastien Nguyen, Roohi Ismail-Khan, Lillian M Smyth, Muralidhar Beeram
Imlunestrant, an Oral Selective Estrogen Receptor Degrader, as Monotherapy and in Combination With Targeted Therapy in Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Phase Ia/Ib EMBER Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Victoria Lee, Xanthe L Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S Guaman, Daniel A Reed, Kendelle J Murphy, Brooke A Pereira, Pauline Mélénec, Cecilia R Chambers, Sharissa L Latham, Helen Lenthall, Elissa K Deenick, Yuanqing Ma, Tri Giang Phan, Elgene Lim, Anthony M Joshua, Stacey N Walters, Shane T Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R Croucher, Andy Philp, Colinda L G J Scheele, David Herrmann, Owen James Sansom, Jennifer P Morton, Antonella Papa, Jody Jonathan Haigh, Max Nobis, Paul Timpson
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse. Science advances 9 (17) (2023)
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Victoria Lee, Xanthe L Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S Guaman, Daniel A Reed, Kendelle J Murphy, Brooke A Pereira, Pauline Mélénec, Cecilia R Chambers, Sharissa L Latham, Helen Lenthall, Elissa K Deenick, Yuanqing Ma, Tri Giang Phan, Elgene Lim, Anthony M Joshua, Stacey N Walters, Shane T Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R Croucher, Andy Philp, Colinda L G J Scheele, David Herrmann, Owen James Sansom, Jennifer P Morton, Antonella Papa, Jody Jonathan Haigh, Max Nobis, Paul Timpson
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse. Science advances 9 (17) (2023)
Komal L Jhaveri, Meritxell Bellet-Ezquerra, Nicholas C Turner, Sherene Loi, Aditya Bardia, Valentina Boni, Joo Hyuk Sohn, Tomas G Neilan, Rafael Villanueva-Vázquez, Peter Kabos, Laura García Estévez, Elena Lopez-Miranda, José Alejandro Pérez-Fidalgo, Jose Manuel Perez-Garcia, Jiajie Yu, Jill Fredrickson, Heather M Moore, Ching-Wei Chang, John W Bond, Jennifer Eng-Wong, Mary R Gates, Elgene Lim
Phase Ia/b Study of Giredestrant ±Palbociclib and ±Luteinizing Hormone-releasing Hormone Agonists in Estrogen Receptor-positive, HER2-negative, Locally Advanced/Metastatic Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Joshua Hurwitz, Lucy Roxana Haggstrom, Elgene Lim
Antibody-Drug Conjugates: Ushering in a New Era of Cancer Therapy. Pharmaceutics 15 (8) (2023)
Joanne Wing Yan Chiu, Soo-Chin Lee, Chung Man James Ho, Yeon Hee Park, Ta-Chung Chao, Sung-Bae Kim, Elgene Lim, Ching-Hung Lin, Sherene Loi, Su Ying Low, Lynette Li San Teo, Winnie Yeo, Rebecca A Dent
Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel. Drug safety (2023)
Teesha D Downton, Fiona Zhou, Davendra Segara, Rinath M Jeselsohn, Elgene Lim
Oral Selective Estrogen Receptor Degraders (SERDs) in Breast Cancer: Advances, Challenges, and Current Status. Drug design, development and therapy 16 (2022)
Riley J Morrow, Amr H Allam, Belinda Yeo, Siddhartha Deb, Carmel Murone, Elgene Lim, Cameron N Johnstone, Matthias Ernst
Paracrine IL-6 Signaling Confers Proliferation between Heterogeneous Inflammatory Breast Cancer Sub-Clones. Cancers 14 (9) (2022)
Jean Berthelet, Momeneh Foroutan, Dharmesh D Bhuva, Holly J Whitfield, Farrah El-Saafin, Joseph Cursons, Antonin Serrano, Michal Merdas, Elgene Lim, Emmanuelle Charafe-Jauffret, Christophe Ginestier, Matthias Ernst, Frédéric Hollande, Robin L Anderson, Bhupinder Pal, Belinda Yeo, Melissa J Davis, Delphine Merino
Computational Screening of Anti-Cancer Drugs Identifies a New BRCA Independent Gene Expression Signature to Predict Breast Cancer Sensitivity to Cisplatin. Cancers 14 (10) (2022)
Lauren Julia Brown, Joanna Achinger-Kawecka, Neil Portman, Susan Clark, Clare Stirzaker, Elgene Lim
Epigenetic Therapies and Biomarkers in Breast Cancer. Cancers 14 (3) (2022)
Keith Wong, Gemma Sheehan-Dare, Andrew Nguyen, Bao Ho, Victor Liu, Jonathan Lee, Lauren Julia Brown, Rachel Dear, Lyn Chan, Shikha Sharma, Alessandra Malaroda, Isabelle Smith, Elgene Lim, Louise Emmett
64 Cu-SAR-Bombesin PET-CT Imaging in the Staging of Estrogen/Progesterone Receptor Positive, HER2 Negative Metastatic Breast Cancer Patients: Safety, Dosimetry and Feasibility in a Phase I Trial. Pharmaceuticals (Basel, Switzerland) 15 (7) (2022)
Lucy Roxana Haggstrom, Janette L Vardy, Emma-Kate Carson, Davendra Segara, Elgene Lim, Belinda E Kiely
Effects of Endocrine Therapy on Cognitive Function in Patients with Breast Cancer: A Comprehensive Review. Cancers 14 (4) (2022)
Neil Portman, Elgene Lim
A new sophistication for breast cancer PDXs. Nature cancer 3 (2) (2022)
Elgene Lim, Frances Boyle, Meena Okera, Sherene Loi, Sema Sezgin Goksu, Gertjan van Hal, Sonya C Chapman, Jonathon Colby Gable, Yanyun Chen, Gregory L Price, Anwar M Hossain, M Corona Gainford, Meritxell Bellet Ezquerra
An open label, randomized phase 2 trial assessing the impact of food on the tolerability of abemaciclib in patients with advanced breast cancer. Breast cancer research and treatment 195 (3) (2022)
Michael Papanicolaou, Amelia L Parker, Michelle Yam, Elysse C Filipe, Sunny Z Wu, Jessica L Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N Skhinas, Morghan C Lucas, David Herrmann, Max Nobis, Brooke A Pereira, Andrew M K Law, Lesley Castillo, Kendelle J Murphy, Anaiis Zaratzian, Jordan F Hastings, David R Croucher, Elgene Lim, Brian G Oliver, Fatima Valdes Mora, Benjamin L Parker, David Gallego Ortega, Alexander Swarbrick, Sandra O'Toole, Paul Timpson, Thomas R Cox
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis. Nature communications 13 (1) (2022)
Sunny Z Wu, Ghamdan Al-Eryani, Daniel Lee Roden, Simon R Junankar, Kate Harvey, Alma Andersson, Aatish Thennavan, Chenfei Wang, James R Torpy, Nenad Bartonicek, Taopeng Wang, Ludvig Larsson, Dominik C Kaczorowski, Neil I Weisenfeld, Cedric R Uytingco, Jennifer G Chew, Zachary W Bent, Chia-Ling Chan, Vikkitharan Gnanasambandapillai, Charles-Antoine Dutertre, Laurence Gluch, Mun N Hui, Jane Beith, Andrew Parker, Elizabeth Robbins, Davendra Segara, Caroline Cooper, Cindy Mak, Belinda Chan, Sanjay Warrier, Florent Ginhoux, Ewan Millar, Joseph E Powell, Stephen R Williams, X Shirley Liu, Sandra O'Toole, Elgene Lim, Joakim Lundeberg, Charles M Perou, Alexander Swarbrick
A single-cell and spatially resolved atlas of human breast cancers. Nature genetics 53 (9) (2021)
Lauren J Brown, Thomas Meredith, Jie Yu, Anushka Patel, Bruce C Neal, Clare Arnott, Elgene Lim
Heart Failure Therapies for the Prevention of HER2-Monoclonal Antibody-Mediated Cardiotoxicity: A Systematic Review and Meta-Analysis of Randomized Trials. Cancers 13 (21) (2021)
Theresa E Hickey, Luke A Selth, Kee Ming Chia, Geraldine Laven-Law, Heloisa H Milioli, Daniel Lee Roden, Shalini Jindal, Mun Hui, Jessica Finlay-Schultz, Esmaeil Ebrahimie, Stephen N Birrell, Suzan Stelloo, Richard Iggo, Sarah Alexandrou, C Elizabeth Caldon, Tarek M Abdel-Fatah, Ian O Ellis, Wilbert Zwart, Carlo Palmieri, Carol A Sartorius, Alexander Swarbrick, Elgene Lim, Jason S Carroll, Wayne D Tilley
The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. Nature medicine 27 (2) (2021)
Carla L Alves, Sidse Ehmsen, Mikkel G Terp, Neil Portman, Martina Tuttolomondo, Odd L Gammelgaard, Monique F Hundebøl, Kamila Kaminska, Lene E Johansen, Martin Bak, Gabriella Honeth, Ana Bosch, Elgene Lim, Henrik Jørn Ditzel
Publisher Correction: Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer. Nature communications 12 (1) (2021)
Allegra Freelander, Lauren J Brown, Andrew Parker, Davendra Segara, Neil Portman, Brandon Lau, Elgene Lim
Molecular Biomarkers for Contemporary Therapies in Hormone Receptor-Positive Breast Cancer. Genes 12 (2) (2021)
Sanjeev Kumar, Allegra Freelander, Elgene Lim
Type 1 Nuclear Receptor Activity in Breast Cancer: Translating Preclinical Insights to the Clinic. Cancers 13 (19) (2021)
Diar Aziz, Neil Portman, Kristine J Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop-Guevara, Zoe Phan, Aliza Yong, Ashleigh Wilkinson, C Marcelo Sergio, Danielle Ferraro, Dariush Etemadmoghadam, David D Bowtell, null null, Violeta Serra, Paul Waring, Elgene Lim, C Elizabeth Caldon
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition. NPJ breast cancer 7 (1) (2021)
Carla L Alves, Sidse Ehmsen, Mikkel G Terp, Neil Portman, Martina Tuttolomondo, Odd L Gammelgaard, Monique F Hundebøl, Kamila Kaminska, Lene E Johansen, Martin Bak, Gabriella Honeth, Ana Bosch, Elgene Lim, Henrik Jørn Ditzel
Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer. Nature communications 12 (1) (2021)