Ernest Fraenkel

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 44

Top Topics

Positive Breast Cancer

Amyotrophic Lateral Sclerosis

Top Venues

Nature communications

Nature computational science

Scientific data

Clinical cancer research : an official journal of the American Association for Cancer Research

This page only lists publications with an associated author ORCID identifier.

Publications

Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Maxwell P Gold, Winnie Ong, Andrew M Masteller, David R Ghasemi, Julie Anne Galindo, Noel R Park, Nhan C Huynh, Aneesh Donde, Veronika Pister, Raul A Saurez, Maria C Vladoiu, Grace H Hwang, Tanja Eisemann, Laura K Donovan, Adam D Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A Segal, Robert J Wechsler-Reya, Jill P Mesirov, Andrey Korshunov, Kristian W Pajtler, Scott L Pomeroy, Olivier Ayrault, Shawn M Davidson, Jennifer A Cotter, Michael D Taylor, Ernest Fraenkel
Developmental basis of SHH medulloblastoma heterogeneity. Nature communications 15 (1) (2024)
Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva, Aneesh Donde, Aaron Frank, Susan Lei, null null, Jennifer E Van Eyk, Steve Finkbeiner, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, Ernest Fraenkel
Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls. Nature communications 15 (1) (2024)
Maxwell P Gold, Winnie Ong, Andrew M Masteller, David R Ghasemi, Julie Anne Galindo, Noel R Park, Nhan C Huynh, Aneesh Donde, Veronika Pister, Raul A Saurez, Maria C Vladoiu, Grace H Hwang, Tanja Eisemann, Laura K Donovan, Adam D Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A Segal, Robert J Wechsler-Reya, Jill P Mesirov, Andrey Korshunov, Kristian W Pajtler, Scott L Pomeroy, Olivier Ayrault, Shawn M Davidson, Jennifer A Cotter, Michael D Taylor, Ernest Fraenkel
Developmental basis of SHH medulloblastoma heterogeneity. Nature communications 15 (1) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Maxwell P Gold, Winnie Ong, Andrew M Masteller, David R Ghasemi, Julie Anne Galindo, Noel R Park, Nhan C Huynh, Aneesh Donde, Veronika Pister, Raul A Saurez, Maria C Vladoiu, Grace H Hwang, Tanja Eisemann, Laura K Donovan, Adam D Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A Segal, Robert J Wechsler-Reya, Jill P Mesirov, Andrey Korshunov, Kristian W Pajtler, Scott L Pomeroy, Olivier Ayrault, Shawn M Davidson, Jennifer A Cotter, Michael D Taylor, Ernest Fraenkel
Developmental basis of SHH medulloblastoma heterogeneity. Nature communications 15 (1) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva, Aneesh Donde, Aaron Frank, Susan Lei, null null, Jennifer E Van Eyk, Steve Finkbeiner, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, Ernest Fraenkel
Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls. Nature communications 15 (1) (2024)
Maxwell P Gold, Winnie Ong, Andrew M Masteller, David R Ghasemi, Julie Anne Galindo, Noel R Park, Nhan C Huynh, Aneesh Donde, Veronika Pister, Raul A Saurez, Maria C Vladoiu, Grace H Hwang, Tanja Eisemann, Laura K Donovan, Adam D Walker, Joseph Benetatos, Christelle Dufour, Livia Garzia, Rosalind A Segal, Robert J Wechsler-Reya, Jill P Mesirov, Andrey Korshunov, Kristian W Pajtler, Scott L Pomeroy, Olivier Ayrault, Shawn M Davidson, Jennifer A Cotter, Michael D Taylor, Ernest Fraenkel
Developmental basis of SHH medulloblastoma heterogeneity. Nature communications 15 (1) (2024)
Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva, Aneesh Donde, Aaron Frank, Susan Lei, null null, Jennifer E Van Eyk, Steve Finkbeiner, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, Ernest Fraenkel
Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls. Nature communications 15 (1) (2024)
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Heraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen, Ariel Feiglin, Weihan Liu, Francisco Hermida-Prado, Nikolas Kesten, Wen Ma, Carmine De Angelis, Antonio Morlando, Madison O'Donnell, Sergey Naumenko, Shixia Huang, Quang-De Nguyen, Ying Huang, Luca Malorni, Johann S Bergholz Villafane, Jean J Zhao, Ernest Fraenkel, Elgene Lim, Rachel Schiff, Geoffrey I Shapiro, Rinath M Jeselsohn
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (9) (2024)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Pier Paolo Peruzzi, Christine Dominas, Geoffrey G Fell, Joshua D Bernstock, Sarah E Blitz, Debora Mazzetti, Mykola Zdioruk, Hassan Y Dawood, Daniel V Triggs, Sebastian W Ahn, Sharath K Bhagavatula, Shawn M Davidson, Zuzana Tatarova, Michael Pannell, Kyla Truman, Anna Ball, Maxwell P Gold, Veronika Pister, Ernest Fraenkel, E Antonio Chiocca, Keith L Ligon, Patrick Yung Wen, Oliver Jonas
Intratumoral drug-releasing microdevices allow in situ high-throughput pharmaco phenotyping in patients with gliomas. Science translational medicine 15 (712) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Andrea D Matlock, Vineet Vaibhav, Ronald Holewinski, Vidya Venkatraman, Victoria Dardov, Danica-Mae Manalo, Brandon Shelley, Loren Ornelas, Maria Banuelos, Berhan Mandefro, Renan Escalante-Chong, Jonathan Li, Steven Finkbeiner, Ernest Fraenkel, Jeffrey D Rothstein, Leslie M Thompson, Dhruv Sareen, Clive N Svendsen, null null, Jennifer E Van Eyk
NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Scientific data 10 (1) (2023)
Owen S Chapman, Jens Luebeck, Sunita Sridhar, Ivy Tsz-Lo Wong, Deobrat Dixit, Shanqing Wang, Gino Prasad, Utkrisht Rajkumar, Meghana S Pagadala, Jon D Larson, Britney Jiayu He, King L Hung, Joshua T Lange, Siavash R Dehkordi, Sahaana Chandran, Miriam Adam, Ling Morgan, Sameena Wani, Ashutosh Tiwari, Caitlin Guccione, Yingxi Lin, Aditi Dutta, Yan Yuen Lo, Edwin Juarez, James T Robinson, Andrey Korshunov, John-Edward A Michaels, Yoon-Jae Cho, Denise M Malicki, Nicole G Coufal, Michael L Levy, Charlotte Hobbs, Richard H Scheuermann, John R Crawford, Scott L Pomeroy, Jeremy N Rich, Xinlian Zhang, Howard Y Chang, Jesse R Dixon, Anindya Bagchi, Aniruddha J Deshpande, Hannah Carter, Ernest Fraenkel, Paul S Mischel, Robert J Wechsler-Reya, Vineet Bafna, Jill P Mesirov, Lukas Chavez
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nature genetics (2023)
Soukayna Mouatadid, Paulo Orenstein, Genevieve Flaspohler, Judah Cohen, Miruna Oprescu, Ernest Fraenkel, Lester Mackey
Adaptive bias correction for improved subseasonal forecasting. Nature communications 14 (1) (2023)
Elad Yom-Tov, Indu Navar, Ernest Fraenkel, James D Berry
Identifying amyotrophic lateral sclerosis through interactions with an internet search engine. Muscle & nerve (2023)
Ang Cui, Teddy Huang, Shuqiang Li, Aileen Ma, Jorge L Pérez, Chris Sander, Derin B Keskin, Catherine J Wu, Ernest Fraenkel, Nir Hacohen
Dictionary of immune responses to cytokines at single-cell resolution. Nature (2023)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Divya Ramamoorthy, Kristen Severson, Soumya Ghosh, Karen Sachs, null null, Jonathan D Glass, Christina N Fournier, null null, null null, Todd M Herrington, James D Berry, Kenney Ng, Ernest Fraenkel
Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data. Nature computational science 2 (9) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Sean M Gross, Mark A Dane, Rebecca L Smith, Kaylyn L Devlin, Ian C McLean, Daniel S Derrick, Caitlin E Mills, Kartik Subramanian, Alexandra B London, Denis Torre, John Erol Evangelista, Daniel J B Clarke, Zhuorui Xie, Cemal Erdem, Nicholas Lyons, Ted Natoli, Sarah Pessa, Xiaodong Lu, James Mullahoo, Jonathan Li, Miriam Adam, Brook Wassie, Moqing Liu, David F Kilburn, Tiera A Liby, Elmar Bucher, Crystal Sanchez-Aguila, Kenneth Daily, Larsson Omberg, Yunguan Wang, Connor Jacobson, Clarence Yapp, Mirra Chung, Dusica Vidovic, Yiling Lu, Stephan C Schürer, Albert Lee, Ajay Pillai, Aravind Subramanian, Malvina Papanastasiou, Ernest Fraenkel, Heidi S Feiler, Gordon B Mills, Jacob D Jaffe, Avi Ma'ayan, Marc R Birtwistle, Peter Karl Sorger, James E Korkola, Joe W Gray, Laura M Heiser
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses. Communications biology 5 (1) (2022)
Emily G Baxi, Terri Thompson, Jonathan Li, Julia A Kaye, Ryan G Lim, Jie Wu, Divya Ramamoorthy, Leandro Lima, Vineet Vaibhav, Andrea Matlock, Aaron Frank, Alyssa N Coyne, Barry Landin, Loren Ornelas, Elizabeth Mosmiller, Sara Thrower, S Michelle Farr, Lindsey Panther, Emilda Gomez, Erick Galvez, Daniel Perez, Imara Meepe, Susan Lei, Berhan Mandefro, Hannah Trost, Louis Pinedo, Maria G Banuelos, Chunyan Liu, Ruby Moran, Veronica Garcia, Michael Workman, Ritchie Ho, Stacia Wyman, Jennifer Roggenbuck, Matthew B Harms, Jennifer Stocksdale, Ricardo Miramontes, Keona Wang, Vidya Venkatraman, Ronald Holewenski, Niveda Sundararaman, Rakhi Pandey, Danica-Mae Manalo, Aneesh Donde, Nhan Huynh, Miriam Adam, Brook T Wassie, Edward Vertudes, Naufa Amirani, Krishna Raja, Reuben Thomas, Lindsey Hayes, Alex Lenail, Aianna Cerezo, Sarah Luppino, Alanna Farrar, Lindsay Pothier, Carolyn Prina, Todd Morgan, Arish Jamil, Sarah Heintzman, Jennifer Jockel-Balsarotti, Elizabeth Karanja, Jesse Markway, Molly McCallum, Ben Joslin, Deniz Alibazoglu, Stephen J Kolb, Senda Ajroud-Driss, Robert H Baloh, Daragh Heitzman, Tim Miller, Jonathan D Glass, Natasha Leanna Patel-Murray, Hong Yu, Ervin Sinani, Prasha Vigneswaran, Alexander V Sherman, Omar Ahmad, Promit Roy, Jay C Beavers, Steven Zeiler, John W Krakauer, Carla Agurto, Guillermo A Cecchi, Mary Bellard, Yogindra Raghav, Karen Sachs, Tobias Ehrenberger, Elizabeth Bruce, Merit E Cudkowicz, Nicholas J Maragakis, Raquel Norel, Jennifer E Van Eyk, Steven Finkbeiner, James Berry, Dhruv Sareen, Leslie M Thompson, Ernest Fraenkel, Clive N Svendsen, Jeffrey D Rothstein
Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nature neuroscience 25 (2) (2022)
Ryan G Lim, Osama Al-Dalahmah, Jie Wu, Maxwell P Gold, Jack C Reidling, Guomei Tang, Miriam Adam, David K Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M Reyes-Ortiz, Alice Lau, Richard A Hickman, Fatima Khan, Fahad Paryani, Alice Tang, Kenneth Ofori, Emily Miyoshi, Neethu Michael, Nicolette McClure, Xena E Flowers, Jean Paul Vonsattel, Shawn Davidson, Vilas Menon, Vivek Swarup, Ernest Fraenkel, James E Goldman, Leslie M Thompson
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation. Nature communications 13 (1) (2022)
Michal Sheffer, Emily Lowry, Nicky Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris C Mader, Jennifer A Roth, Aviad Tsherniak, Samuel S Freeman, Olga Dashevsky, Sara Gandolfi, Samantha Bender, Jordan G Bryan, Cong Zhu, Li Wang, Ifrah Tariq, Govinda M Kamath, Ricardo De Matos Simoes, Eugen Dhimolea, Channing Yu, Yiguo Hu, Olli Dufva, Marios Giannakis, Vasilis Syrgkanis, Ernest Fraenkel, Todd R Golub, Rizwan Romee, Mohamed El Missiry, Aedin C Culhane, Lotte Wieten, Constantine S Mitsiades
Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. Nature genetics 53 (8) (2021)
Estela Area-Gomez, Delfina Larrea, Marta Pera, Rishi R Agrawal, David N Guilfoyle, Leila Pirhaji, Kathleen Shannon, Hirra A Arain, Archana Ashok, Qiuying Chen, Allissa A Dillman, Helen Y Figueroa, Mark R Cookson, Steven S Gross, Ernest Fraenkel, Karen E Duff, Tal Nuriel
APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice. Scientific reports 10 (1) (2020)
Souvarish Sarkar, Michael A Murphy, Eric B Dammer, Abby L Olsen, Srikant Rangaraju, Ernest Fraenkel, Mel B Feany
Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy. NPJ Parkinson's disease 6 (1) (2020)
Natasha L Patel-Murray, Miriam Adam, Nhan Huynh, Brook T Wassie, Pamela Milani, Ernest Fraenkel
A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules. Scientific reports 10 (1) (2020)
Liqun Wang, Jing Xia, Jonathan Li, Tracy L Hagemann, Jeffrey R Jones, Ernest Fraenkel, David A Weitz, Su-Chun Zhang, Albee Messing, Mel B Feany
Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease. Nature communications 9 (1) (2018)
Murodzhon Akhmedov, Amanda J Kedaigle, Renan Escalante Chong, Roberto Montemanni, Francesco Bertoni, Ernest Fraenkel, Ivo Kwee
PCSF: An R-package for network-based interpretation of high-throughput data. PLoS computational biology 13 (7) (2017)
Leila Pirhaji, Pamela Milani, Simona Dalin, Brook T Wassie, Denise E Dunn, Robert J Fenster, Julian Avila-Pacheco, Paul Greengard, Andrew T Chan, Myriam Heiman, Donald C Lo, Ernest Fraenkel
Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements. Nature communications 8 (1) (2017)
Nurcan Tuncbag, Sara J C Gosline, Amanda J Kedaigle, Anthony R Soltis, Anthony Gitter, Ernest Fraenkel
Network-Based Interpretation of Diverse High-Throughput Datasets through the Omics Integrator Software Package. PLoS computational biology 12 (4) (2016)
Leila Pirhaji, Pamela Milani, Mathias Leidl, Timothy Curran, Julian Avila-Pacheco, Andrew T Chan, Forest M White, Alan Saghatelian, Ernest Fraenkel
Revealing disease-associated pathways by network integration of untargeted metabolomics. Nature methods 13 (9) (2016)