Frank B Furnari (Frank Furnari)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Venues

bioRxiv : the preprint server for biology

Life science alliance

Disease models & mechanisms

Neuro-oncology advances

Ludwig Institute for Cancer Research San Diego Branch

UNC Health Care System (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Ludwig Institute for Cancer Research San Diego Branch Jan 01 2016

United States

Full Member :: Tumor Biology

Ludwig Institute for Cancer Research San Diego Branch Nov 02 2011 - Dec 31 2015

United States

Senior Investigator :: Tumor Biology

Ludwig Institute for Cancer Research San Diego Branch Apr 02 2007 - Nov 01 2011

United States

Associate Investigator :: Tumor Biology

Ludwig Institute for Cancer Research San Diego Branch Aug 01 2000 - Apr 01 2007

United States

Assistant Investigator :: Tumor Biology

Ludwig Institute for Cancer Research San Diego Branch Feb 23 1993 - Jul 01 2000

United States

postdoctoral fellow :: Tumor Biology

Education History

UNC Health Care System Aug 15 1987 - Jan 10 1993

United States

PHD :: Microbiology

Publications

Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, David H Gutmann
Stem cell modeling of nervous system tumors. Disease models & mechanisms 17 (2) (2024)
Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, David H Gutmann
Stem cell modeling of nervous system tumors. Disease models & mechanisms 17 (2) (2024)
Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, David H Gutmann
Stem cell modeling of nervous system tumors. Disease models & mechanisms 17 (2) (2024)
Brett Taylor, Nanyun Tang, Yue Hao, Matthew Lee, Sen Peng, Rita Bybee, Lauren Hartman, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Jianhui Ma, Alison D Parisian, Frank B Furnari, Harshil D Dhruv, Michael E Berens
Glioblastoma vulnerability to neddylation inhibition is dependent on PTEN status, and dysregulation of the cell cycle and DNA replication. Neuro-oncology advances 6 (1) (2024)
Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, David H Gutmann
Stem cell modeling of nervous system tumors. Disease models & mechanisms 17 (2) (2024)
Danielle Maeser, Robert F Gruener, Robert T Galvin, Adam Lee, Tomoyuki Koga, Florina-Nicoleta Grigore, Yuta Suzuki, Frank B Furnari, Clark Chen, Rong Stephanie Huang
Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma. Cancers 16 (9) (2024)
Danielle Maeser, Robert F Gruener, Robert T Galvin, Adam Lee, Tomoyuki Koga, Florina-Nicoleta Grigore, Yuta Suzuki, Frank B Furnari, Clark Chen, Rong Stephanie Huang
Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma. Cancers 16 (9) (2024)
Brett Taylor, Nanyun Tang, Yue Hao, Matthew Lee, Sen Peng, Rita Bybee, Lauren Hartman, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Jianhui Ma, Alison D Parisian, Frank B Furnari, Harshil D Dhruv, Michael E Berens
Glioblastoma vulnerability to neddylation inhibition is dependent on PTEN status, and dysregulation of the cell cycle and DNA replication. Neuro-oncology advances 6 (1) (2024)
Brett Taylor, Nanyun Tang, Yue Hao, Matthew Lee, Sen Peng, Rita Bybee, Lauren Hartman, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Jianhui Ma, Alison D Parisian, Frank B Furnari, Harshil D Dhruv, Michael E Berens
Glioblastoma vulnerability to neddylation inhibition is dependent on PTEN status, and dysregulation of the cell cycle and DNA replication. Neuro-oncology advances 6 (1) (2024)
Danielle Maeser, Robert F Gruener, Robert T Galvin, Adam Lee, Tomoyuki Koga, Florina-Nicoleta Grigore, Yuta Suzuki, Frank B Furnari, Clark Chen, Rong Stephanie Huang
Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma. Cancers 16 (9) (2024)
Siavash Raeisi Dehkordi, Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad, Lena Krockenberger, Guanghui Xu, Biswanath Chowdhury, Utkrisht Rajkumar, Ann Caplin, Daniel Muliaditan, Ceyda Coruh, Qiushi Jin, Kristen Turner, Shu Xian Teo, Andy Wing Chun Pang, Ludmil B Alexandrov, Christelle En Lin Chua, Frank B Furnari, Thomas G Paulson, Julie A Law, Howard Y Chang, Feng Yue, Ramanuj DasGupta, Jean Zhao, Paul S Mischel, Vineet Bafna
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. bioRxiv : the preprint server for biology (2023)
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network. Life science alliance 6 (8) (2023)
Siavash Raeisi Dehkordi, Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad, Lena Krockenberger, Guanghui Xu, Biswanath Chowdhury, Utkrisht Rajkumar, Ann Caplin, Daniel Muliaditan, Ceyda Coruh, Qiushi Jin, Kristen Turner, Shu Xian Teo, Andy Wing Chun Pang, Ludmil B Alexandrov, Christelle En Lin Chua, Frank B Furnari, Thomas G Paulson, Julie A Law, Howard Y Chang, Feng Yue, Ramanuj DasGupta, Jean Zhao, Paul S Mischel, Vineet Bafna
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. bioRxiv : the preprint server for biology (2023)
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network. Life science alliance 6 (8) (2023)
Siavash Raeisi Dehkordi, Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad, Lena Krockenberger, Guanghui Xu, Biswanath Chowdhury, Utkrisht Rajkumar, Ann Caplin, Daniel Muliaditan, Ceyda Coruh, Qiushi Jin, Kristen Turner, Shu Xian Teo, Andy Wing Chun Pang, Ludmil B Alexandrov, Christelle En Lin Chua, Frank B Furnari, Thomas G Paulson, Julie A Law, Howard Y Chang, Feng Yue, Ramanuj DasGupta, Jean Zhao, Paul S Mischel, Vineet Bafna
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. bioRxiv : the preprint server for biology (2023)
Kasey R Skinner, Tomoyuki Koga, Shunichiro Miki, Robert F Gruener, Florina-Nicoleta Grigore, Emma H Torii, Davis M Seelig, Yuta Suzuki, Daisuke Kawauchi, Benjamin Lin, Denise M Malicki, Clark C Chen, Etty N Benveniste, Rakesh P Patel, Braden C McFarland, Rong Stephanie Huang, Chris Jones, Alan Mackay, C Ryan Miller, Frank B Furnari
Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars. bioRxiv : the preprint server for biology (2023)
Kasey R Skinner, Tomoyuki Koga, Shunichiro Miki, Robert F Gruener, Florina-Nicoleta Grigore, Emma H Torii, Davis M Seelig, Yuta Suzuki, Daisuke Kawauchi, Benjamin Lin, Denise M Malicki, Clark C Chen, Etty N Benveniste, Rakesh P Patel, Braden C McFarland, Rong Stephanie Huang, Chris Jones, Alan Mackay, C Ryan Miller, Frank B Furnari
Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars. bioRxiv : the preprint server for biology (2023)
Siavash Raeisi Dehkordi, Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad, Lena Krockenberger, Guanghui Xu, Biswanath Chowdhury, Utkrisht Rajkumar, Ann Caplin, Daniel Muliaditan, Ceyda Coruh, Qiushi Jin, Kristen Turner, Shu Xian Teo, Andy Wing Chun Pang, Ludmil B Alexandrov, Christelle En Lin Chua, Frank B Furnari, Thomas G Paulson, Julie A Law, Howard Y Chang, Feng Yue, Ramanuj DasGupta, Jean Zhao, Paul S Mischel, Vineet Bafna
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. bioRxiv : the preprint server for biology (2023)
Raghavendra Vadla, Shunichiro Miki, Brett Taylor, Daisuke Kawauchi, Brandon M Jones, Nidhi Nathwani, Philip Pham, Jonathan Tsang, David A Nathanson, Frank B Furnari
Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex. bioRxiv : the preprint server for biology (2023)
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network. Life science alliance 6 (8) (2023)
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network. Life science alliance 6 (8) (2023)
Siavash Raeisi Dehkordi, Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad, Lena Krockenberger, Guanghui Xu, Biswanath Chowdhury, Utkrisht Rajkumar, Ann Caplin, Daniel Muliaditan, Ceyda Coruh, Qiushi Jin, Kristen Turner, Shu Xian Teo, Andy Wing Chun Pang, Ludmil B Alexandrov, Christelle En Lin Chua, Frank B Furnari, Thomas G Paulson, Julie A Law, Howard Y Chang, Feng Yue, Ramanuj DasGupta, Jean Zhao, Paul S Mischel, Vineet Bafna
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change. bioRxiv : the preprint server for biology (2023)
Jacqueline S Gerritsen, Joseph S Faraguna, Rudy Bonavia, Frank B Furnari, Forest M White
Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network. Life science alliance 6 (8) (2023)
Julia M T Ledderose, Jorge A Benitez, Amanda J Roberts, Rachel Reed, Willem Bintig, Matthew E Larkum, Robert N S Sachdev, Frank B Furnari, Britta J Eickholt
The impact of phosphorylated PTEN at threonine 366 on cortical connectivity and behaviour. Brain : a journal of neurology 145 (10) (2022)
Shayesteh R Ferdosi, Brett Taylor, Matthew Lee, Nanyun Tang, Sen Peng, Rita Bybee, George Reid, Lauren Hartman, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Jianhui Ma, Alison D Parisian, Frank B Furnari, Harshil D Dhruv, Michael E Berens
PTEN loss drives resistance to the neddylation inhibitor MLN4924 in glioblastoma and can be overcome with TOP2A inhibitors. Neuro-oncology 24 (11) (2022)
Nicole Oatman, Nupur Dasgupta, Priyanka Arora, Kwangmin Choi, Mruniya V Gawali, Nishtha Gupta, Sreeja Parameswaran, Joseph Salomone, Julie A Reisz, Sean E Lawler, Frank B Furnari, Cameron Brennan, Jianqiang Wu, Larry Sallans, Gary Gudelsky, Pankaj B Desai, Brian Gebelein, Matthew T Weirauch, Angelo D'Alessandro, Kakajan Komurov, Biplab DasGupta
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Science advances 7 (7) (2021)
Jie Li, Megan M Kaneda, Jun Ma, Ming Li, Ryan M Shepard, Kunal Patel, Tomoyuki Koga, Aaron Sarver, Frank B Furnari, Beibei Xu, Sanjay Dhawan, Jiangfang Ning, Hua Zhu, An-Hua Wu, Gan You, Tao Jiang, Andrew S Venteicher, Jeremy N Rich, Christopher K Glass, Judith A Varner, Clark C Chen
PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response. Proceedings of the National Academy of Sciences of the United States of America 118 (16) (2021)
Alison D Parisian, Tomoyuki Koga, Shunichiro Miki, Pascal D Johann, Marcel Kool, John R Crawford, Frank B Furnari
SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability. Genes & development 34 (19-20) (2020)
Afsheen Banisadr, Mariam Eick, Pranjali Beri, Alison D Parisian, Benjamin Yeoman, Jesse K Placone, Adam J Engler, Frank B Furnari
EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration. Journal of cell science 133 (24) (2020)
Tomoyuki Koga, Isaac A Chaim, Jorge A Benitez, Sebastian Markmiller, Alison D Parisian, Robert F Hevner, Kristen M Turner, Florian M Hessenauer, Matteo D'Antonio, Nam-Phuong D Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D Boyer, John Ravits, Kelly A Frazer, Vineet Bafna, Clark C Chen, Paul S Mischel, Gene W Yeo, Frank B Furnari
Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nature communications 11 (1) (2020)
Tomoyuki Koga, Isaac A Chaim, Jorge A Benitez, Sebastian Markmiller, Alison D Parisian, Robert F Hevner, Kristen M Turner, Florian M Hessenauer, Matteo D'Antonio, Nam-Phuong D Nguyen, Shahram Saberi, Jianhui Ma, Shunichiro Miki, Antonia D Boyer, John Ravits, Kelly A Frazer, Vineet Bafna, Clark C Chen, Paul S Mischel, Gene W Yeo, Frank B Furnari
Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nature communications 11 (1) (2020)
Laura Orellana, Amy H Thorne, Rafael Lema, Johan Gustavsson, Alison D Parisian, Adam Hospital, Tiago N Cordeiro, Pau Bernadó, Andrew M Scott, Isabelle Brun-Heath, Erik Lindahl, Webster K Cavenee, Frank B Furnari, Modesto Orozco
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope. Proceedings of the National Academy of Sciences of the United States of America 116 (20) (2019)
Sarmistha Talukdar, Anjan K Pradhan, Praveen Bhoopathi, Xue-Ning Shen, Laura A August, Jolene J Windle, Devanand Sarkar, Frank B Furnari, Webster K Cavenee, Swadesh K Das, Luni Emdad, Paul B Fisher
Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin. Autophagy 14 (10) (2018)

Frank B Furnari.css-eqlu8i{font-size:small;padding-left:4px;} (Frank Furnari)

Publication Activity (10 Years)

Top Topics

Top Venues

Frank B Furnari (Frank Furnari)