Pieter Van Vlierberghe (P Van Vlierberghe)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2023
Publications (10 Years): 54

Top Topics

Acute Lymphoblastic Leukemia

Top Venues

Science advances

Nature immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Dieter Tulkens, Marthe Boelens, Thomas Naert, Marjolein Carron, Suzan Demuynck, Sylviane Dewaele, Gert Van Isterdael, David Creytens, Tim Pieters, Steven Goossens, Pieter Van Vlierberghe, Kris Vleminckx
Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis. Leukemia (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology (2023)
Lien Provez, Tom Putteman, Mattias Landfors, Juliette Roels, Lindy Reunes, Sara T'Sas, Wouter Van Loocke, Béatrice Lintermans, Stien De Coninck, Morgan Thenoz, Wouter Sleeckx, Natalia Maćkowska, Tom Taghon, Marc R Mansour, Nadine Farah, Koen Norga, Peter Vandenberghe, Rishi Sury Kotecha, Steven Goossens, Sofie Degerman, Renate De Smedt, Pieter Van Vlierberghe
Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma. Cancers 15 (3) (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology (2023)
Bieke Decaesteker, Amber Louwaige, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D'haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S Roberts, Johannes Hubertus Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark W Zimmerman, Katleen De Preter, Frank Speleman
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry. Nature communications 14 (1) (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology 24 (3) (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology 24 (3) (2023)
Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Boehme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van De Walle, Stephanie Sontag, Jolien Vandewalle, Bart Vandekerckhove, Georges Leclerq, Pieter Van Vlierberghe, Claude Libert, Filip Van Nieuwerburgh, Roman Fischer, Roland E Kontermann, Klaus Pfizenmaier, Gina Doody, Martin Zenke, Tom Taghon
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF. Nature immunology 24 (3) (2023)
Lien Provez, Tom Putteman, Mattias Landfors, Juliette Roels, Lindy Reunes, Sara T'Sas, Wouter Van Loocke, Béatrice Lintermans, Stien De Coninck, Morgan Thenoz, Wouter Sleeckx, Natalia Maćkowska, Tom Taghon, Marc R Mansour, Nadine Farah, Koen Norga, Peter Vandenberghe, Rishi Sury Kotecha, Steven Goossens, Sofie Degerman, Renate De Smedt, Pieter Van Vlierberghe
Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma. Cancers 15 (3) (2023)
Richard Eric Kast, Alex Alfieri, Hazem I Assi, Terry C Burns, Ashraf M Elyamany, Maria Gonzales Cao, Georg Karpel-Massler, Christine Marosi, Michael E Salacz, Iacopo Sardi, Pieter Van Vlierberghe, Mohamed Saad Zaghloul, Marc-Eric Halatsch
MDACT: A New Principle of Adjunctive Cancer Treatment Using Combinations of Multiple Repurposed Drugs, with an Example Regimen. Cancers 14 (10) (2022)
Dieter Tulkens, Dionysia Dimitrakopoulou, Marthe Boelens, Tom Van Nieuwenhuysen, Suzan Demuynck, Wendy Toussaint, David Creytens, Pieter Van Vlierberghe, Kris Vleminckx
Engraftment of Allotransplanted Tumor Cells in Adult rag2 Mutant Xenopus tropicalis . Cancers 14 (19) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Sigrid Wahlen, Filip Matthijssens, Wouter Van Loocke, Sylvie Taveirne, Laura Kiekens, Eva Persyn, Els Van Ammel, Zenzi De Vos, Stijn De Munter, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, Georges Leclerq
The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency. eLife 11 (2022)
Monika Drobna, Natalia Maćkowska, Roman Jaksik, Maria Kosmalska, Bronisława Szarzyńska, Monika Lejman, Łukasz Sędek, Shaji K Kumar, Tom Taghon, Pieter Van Vlierberghe, Michał Witt, Małgorzata Dawidowska
Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL: Focus on miR-363-3p and promoter methylation. Genes, chromosomes & cancer 61 (12) (2022)
Eva Persyn, Sigrid Wahlen, Laura Kiekens, Sylvie Taveirne, Wouter Van Loocke, Els Van Ammel, Filip Van Nieuwerburgh, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, Georges Leclerq
TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality. International journal of molecular sciences 23 (19) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Tim Pieters, André Almeida, Sara T'Sas, Kelly Lemeire, Tino Hochepied, Geert Berx, Alex Kentsis, Steven Goossens, Pieter Van Vlierberghe
Myb drives B-cell neoplasms and myeloid malignancies in vivo. Blood advances 6 (10) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Qi Jin, Blanca T Gutierrez-Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Van Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L Safgren, Yi-Chien Tsai, Beat C Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia. Science advances 8 (49) (2022)
Maaike Van Trimpont, Evelien Peeters, Yanti De Visser, Amanda M Schalk, Veerle Mondelaers, Barbara De Moerloose, Arnon Lavie, Tim Lammens, Steven Goossens, Pieter Van Vlierberghe
Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy. Cancers 14 (4) (2022)
Erwin Pannecoucke, Maaike Van Trimpont, Johan Desmet, Tim Pieters, Lindy Reunes, Lisa Demoen, Marnik Vuylsteke, Stefan Loverix, Karen Vandenbroucke, Philippe Alard, Paula Henderikx, Sabrina Deroo, Franky Baatz, Eric Lorent, Sophie Thiolloy, Klaartje Somers, Yvonne McGrath, Pieter Van Vlierberghe, Ignace Lasters, Savvas N Savvides
Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Science advances 7 (13) (2021)
Emilie Logie, Chandra S Chirumamilla, Claudina Perez Novo, Priyanka Shaw, Ken Declerck, Ajay Palagani, Savithri Rangarajan, Bart Cuypers, Nicolas De Neuter, Fazil Mobashar Hussain Urf Turabe, Navin Kumar Verma, Annemie Bogaerts, Kris Laukens, Fritz Offner, Pieter Van Vlierberghe, Xaveer Van Ostade, Wim Vanden Berghe
Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells. Cancers 13 (7) (2021)
Despoina Kerselidou, Bushra Saeed Dohai, David Roy Nelson, Sarah Daakour, Nicolas De Cock, Zahra Al Oula Hassoun, Dae-Kyum Kim, Julien Olivet, Diana C El Assal, Ashish Jaiswal, Amnah Alzahmi, Deeya Saha, Charlotte Pain, Filip Matthijssens, Pierre Lemaitre, Michael Herfs, Julien Chapuis, Bart Ghesquiere, Didier Vertommen, Verena Kriechbaumer, Kèvin Knoops, Carmen Lopez-Iglesias, Marc van Zandvoort, Jean-Charles Lambert, Julien Hanson, Christophe J Desmet, Marc Thiry, Kyle J Lauersen, Marc Vidal, Pieter Van Vlierberghe, Franck Dequiedt, Kourosh Salehi-Ashtiani, Jean-Claude Twizere
Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells. Science advances 7 (19) (2021)
Tim Pieters, Sara T'Sas, Stijn Vanhee, André Almeida, Yasmine Driege, Juliette Roels, Wouter Van Loocke, Willem Daneels, Mathijs Baens, Arnaud Marchand, Maaike Van Trimpont, Filip Matthijssens, Julie Morscio, Kelly Lemeire, Béatrice Lintermans, Lindy Reunes, Patrick Chaltin, Fritz Offner, Jo Van Dorpe, Tino Hochepied, Geert Berx, Rudi Beyaert, Jens Staal, Pieter Van Vlierberghe, Steven Goossens
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice. The Journal of experimental medicine 218 (10) (2021)
Valentina Bardelli, Silvia Arniani, Valentina Pierini, Tiziana Pierini, Danika Di Giacomo, Paolo Gorello, Martina Moretti, Fabrizia Pellanera, Loredana Elia, Antonella Vitale, Clelia Tiziana Storlazzi, Doron Tolomeo, Elena Mastrodicasa, Maurizio Caniglia, Sabina Chiaretti, Loredana Ruggeri, Giovanni Roti, Claire Schwab, Christine J Harrison, André Almeida, Tim Pieters, Pieter Van Vlierberghe, Cristina Mecucci, Roberta La Starza
MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia. Genes, chromosomes & cancer 60 (7) (2021)
Emilie Logie, Claudina Perez Novo, Amber Driesen, Pieter Van Vlierberghe, Wim Vanden Berghe
Phosphocatalytic Kinome Activity Profiling of Apoptotic and Ferroptotic Agents in Multiple Myeloma Cells. International journal of molecular sciences 22 (23) (2021)
Siska Van Belle, Sara El Ashkar, Kateřina Čermáková, Filip Matthijssens, Steven Goossens, Alessandro Canella, Courtney H Hodges, Frauke Christ, Jan De Rijck, Pieter Van Vlierberghe, Vaclav Veverka, Zeger Debyser
Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival. Cells 10 (1) (2021)
Hesham D Abdulla, Anh Vo, Benjamin J Shields, Tenae J Davies, Jacob T Jackson, Raed Alserihi, Elizabeth M Viney, Tin Wong, Feng Alex Yan, Nicholas C Wong, Lisa Demoen, David J Curtis, Warren S Alexander, Pieter Van Vlierberghe, Ross A Dickins, Matthew P McCormack
T-ALL can evolve to oncogene independence. Leukemia 35 (8) (2021)
Juliette Roels, Anna A Kuchmiy, Matthias De Decker, Steven Strubbe, Marieke Lavaert, Kai Ling Liang, Georges Leclerq, Bart Vandekerckhove, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development. Nature immunology 21 (10) (2020)
Siebe Loontiens, Suzanne Vanhauwaert, Lisa Depestel, Givani Dewyn, Wouter Van Loocke, Finola E Moore, Elaine G Garcia, Lance Batchelor, Chiara Borga, Barbara Squiban, Megan Malone-Perez, Pieter-Jan Volders, Volodimir Olexiouk, Pieter Van Vlierberghe, David M Langenau, J Kimble Frazer, Kaat Durink, Frank Speleman
A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models. Leukemia 34 (12) (2020)
Karolina Slowicka, Ioanna Petta, Gillian Blancke, Esther Hoste, Emilie Dumas, Mozes Sze, Hanna Vikkula, Enrico Radaelli, Jody J Haigh, Sven Jonckheere, Joachim Taminau, Niels Vandamme, Andy Wullaert, Eugene Tulchinsky, David Nittner, Pieter Van Vlierberghe, Gert De Hertogh, Pamela Baldin, Hakki Emre Etlioglu, Pratyaksha Wirapati, Louis Boon, Bart N Lambrecht, Chris Callewaert, Sabine Tejpar, Steven Goossens, Geert Berx, Lars Vereecke, Geert van Loo
Zeb2 drives invasive and microbiota-dependent colon carcinoma. Nature cancer 1 (6) (2020)
Valeria Tosello, Deborah Bongiovanni, Jingjing Liu, Qingfei Pan, Koon-Kiu Yan, Valentina Saccomani, Maaike Van Trimpont, Marco Pizzi, Martina Mazzoni, Angelo Paolo Dei Tos, Alberto Amadori, Paola Zanovello, Pieter Van Vlierberghe, Jiyang Yu, Erich Piovan
Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination. Leukemia 35 (4) (2020)
Anne-Catherine Dolens, Kaat Durinck, Marieke Lavaert, Joni Van der Meulen, Imke Velghe, Jelle De Medts, Karin Weening, Juliette Roels, Katrien De Mulder, Pieter-Jan Volders, Katleen De Preter, Tessa Kerre, Bart Vandekerckhove, Georges Leclercq, Jo Vandesompele, Pieter Mestdagh, Pieter Van Vlierberghe, Frank Speleman, Tom Taghon
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development. EMBO reports 21 (5) (2020)
E G Garcia, Alexandra Veloso, M L Oliveira, James R Allen, Siebe Loontiens, D Brunson, D Do, Chuan Yan, R Morris, S Iyer, Sara P Garcia, N Iftimia, W Van Loocke, F Matthijssens, K McCarthy, Joao T Barata, Frank Speleman, Tom Taghon, Alejandro Gutierrez, Pieter Van Vlierberghe, W Haas, J S Blackburn, David M Langenau
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia 35 (3) (2020)
Andreas Kloetgen, Palaniraja Thandapani, Panagiotis Ntziachristos, Yohana Ghebrechristos, Sofia Nomikou, Charalampos Lazaris, Xufeng Chen, Hai Hu, Sofia Bakogianni, Jingjing Wang, Yi Fu, Francesco Boccalatte, Hua Zhong, Elisabeth Paietta, Thomas Trimarchi, Yixing Zhu, Pieter Van Vlierberghe, Giorgio Ga Inghirami, Timothee Lionnet, Iannis Aifantis, Aristotelis Tsirigos
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia. Nature genetics 52 (4) (2020)
Mattias Hofmans, Stefan Suciu, Alina Ferster, Pieter Van Vlierberghe, Françoise Mazingue, Nicolas Sirvent, Vitor Costa, Karima Yakouben, Catherine Paillard, Anne Uyttebroeck, Dominique Plantaz, Geneviève Plat, Pauline Simon, Frédéric Millot, Marilyne Poirée, Jutte van der Werff Ten Bosch, Caroline Piette, Odile Minckes, Pierre Rohrlich, Sandrine Girard, Hélène Cavé, Yves Bertrand, Barbara De Moerloose
Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL). British journal of haematology 186 (5) (2019)
Tim Pieters, Sara T'Sas, Lisa Demoen, André Almeida, Lieven Haenebalcke, Filip Matthijssens, Kelly Lemeire, Jinke D'Hont, Frederique Van Rockeghem, Tino Hochepied, Beatrice Lintermans, Lindy Reunes, Tim Lammens, Geert Berx, Jody J Haigh, Steven Goossens, Pieter Van Vlierberghe
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies. Scientific reports 9 (1) (2019)
Hexiu Su, Juncheng Hu, Liang Huang, Yang Yang, Morgan Thenoz, Anna Kuchmiy, Yufeng Hu, Peng Li, Hui Feng, Yu Zhou, Tom Taghon, Pieter Van Vlierberghe, Guoliang Qing, Zhichao Chen, Hudan Liu
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival. Nature communications 9 (1) (2018)
Steven Goossens, Pieter Van Vlierberghe
Novel oncogenic noncoding mutations in T-ALL. Blood 129 (24) (2018)
Valeria Tosello, Gloria Milani, Annalisa Martines, Nadia Macri, Wouder Van Loocke, Filip Matthijssens, Barbara Buldini, Sonia Anna Minuzzo, Deborah Bongiovanni, Richard Fabian Schumacher, Alberto Amadori, Pieter Van Vlierberghe, Erich Piovan
A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia. Cells 7 (10) (2018)
Ingrid M Ariës, Kimberly Bodaar, Salmaan A Karim, Triona Ni Chonghaile, Laura Hinze, Melissa A Burns, Maren Pfirrmann, James Degar, Jack T Landrigan, Sebastian Balbach, Sofie Peirs, Björn Menten, Randi Isenhart, Kristen E Stevenson, Donna S Neuberg, Meenakshi Devidas, Mignon L Loh, Stephen P Hunger, David T Teachey, Karen R Rabin, Stuart S Winter, Kimberly P Dunsmore, Brent L Wood, Lewis B Silverman, Stephen E Sallan, Pieter Van Vlierberghe, Stuart H Orkin, Birgit Knoechel, Anthony G Letai, Alejandro Gutierrez
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia. The Journal of experimental medicine 215 (12) (2018)
Marjolijn Renard, Suzanne Vanhauwaert, Marine Vanhomwegen, Ali Rihani, Niels Vandamme, Steven Goossens, Geert Berx, Pieter Van Vlierberghe, Jody J Haigh, Bieke Decaesteker, Jolien Van Laere, Irina Lambertz, Frank Speleman, Jo Vandesompele, Andy Willaert
Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice. Scientific reports 8 (1) (2018)
Gloria Milani, Filip Matthijssens, Wouter Van Loocke, Kaat Durinck, Juliette Roels, Sofie Peirs, Morgan Thénoz, Tim Pieters, Lindy Reunes, Beatrice Lintermans, Niels Vandamme, Tim Lammens, Nadine Van Roy, Filip Van Nieuwerburgh, Dieter Deforce, Claire Schwab, Susana Raimondi, Luciano Dalla Pozza, Andrew J Carroll, Barbara De Moerloose, Yves Benoit, Steven Goossens, Geert Berx, Christine J Harrison, Giuseppe Basso, Hélène Cavé, Rosemary Sutton, Vahid Asnafi, Jules Meijerink, Charles G Mullighan, Mignon Loh, Pieter Van Vlierberghe
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia. British journal of haematology 185 (1) (2018)
Annelynn Wallaert, Wouter Van Loocke, Lucie Hernandez, Tom Taghon, Frank Speleman, Pieter Van Vlierberghe
Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing. Scientific reports 7 (1) (2017)
Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser, Jan De Rijck
LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis. Blood 131 (1) (2017)
S Degryse, C E de Bock, S Demeyer, I Govaerts, S Bornschein, D Verbeke, K Jacobs, S Binos, D A Skerrett-Byrne, H C Murray, N M Verrills, Pieter Van Vlierberghe, J Cools, M D Dun
Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia. Leukemia 32 (3) (2017)
Hetty Hilde Helsmoortel, Silvia Bresolin, Tim Lammens, Hélène Cavé, Peter Noellke, Aurélie Caye, Farzaneh Ghazavi, Andrica de Vries, Henrik Hasle, Veerle Labarque, Riccardo Masetti, Jan Stary, Marry M M van den Heuvel-Eibrink, Jan Philippé, Nadine Van Roy, Yves Benoit, Frank Speleman, Charlotte Niemeyer, Christian Flotho, Giuseppe Basso, Geertruy Te Kronnie, Pieter Van Vlierberghe, Barbara De Moerloose
LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia. Blood 127 (9) (2015)