Franklin Lei Zhong (Franklin L Zhong, Franklin Zhong)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 17

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

The Journal of experimental medicine

Nature communications

Science (New York, N.Y.)

Nanyang Technological University

Stanford University School of Medicine (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Nanyang Technological University

Singapore

Assistant Professor :: Lee Kong Chian School of Medicine

Skin Research Insitute of Singapore Apr 01 2019

Singapore

Group Leader

Education History

Stanford University School of Medicine Sep 01 2008 - May 01 2014

United States

PHD :: Cancer Biology Program

Publications

Pritisha Rozario, Miriam Pinilla, Leana Gorse, Anna Constance Vind, Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, José Francisco Martínez, Swat Kim Kerk, Zhewang Lin, John C Chambers, Simon Bekker-Jensen, Etienne Meunier, Franklin Lei Zhong
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Pritisha Rozario, Miriam Pinilla, Leana Gorse, Anna Constance Vind, Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, José Francisco Martínez, Swat Kim Kerk, Zhewang Lin, John C Chambers, Simon Bekker-Jensen, Etienne Meunier, Franklin Lei Zhong
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Pritisha Rozario, Miriam Pinilla, Leana Gorse, Anna Constance Vind, Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, José Francisco Martínez, Swat Kim Kerk, Zhewang Lin, John C Chambers, Simon Bekker-Jensen, Etienne Meunier, Franklin Lei Zhong
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Pritisha Rozario, Miriam Pinilla, Leana Gorse, Anna Constance Vind, Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, José Francisco Martínez, Swat Kim Kerk, Zhewang Lin, John C Chambers, Simon Bekker-Jensen, Etienne Meunier, Franklin Lei Zhong
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Pritisha Rozario, Miriam Pinilla, Leana Gorse, Anna Constance Vind, Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, José Francisco Martínez, Swat Kim Kerk, Zhewang Lin, John C Chambers, Simon Bekker-Jensen, Etienne Meunier, Franklin Lei Zhong
Mechanistic basis for potassium efflux-driven activation of the human NLRP1 inflammasome. Proceedings of the National Academy of Sciences of the United States of America 121 (2) (2024)
Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, Khek-Chian Tham, Pritisha Rozario, Chrissie Kaishi Lim, Ying Xiu Toh, Zhi Heng Lau, Sophie Charlotte Binder, Jacob Mayer, Carine Bonnard, Florian Ingo Schmidt, John Edmund Armourer Common, Franklin Lei Zhong
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis. The Journal of experimental medicine 220 (10) (2023)
Miriam Pinilla, Raoul Mazars, Romain Vergé, Leana Gorse, Margaux Paradis, Bastien Suire, Karin Santoni, Kim Samirah Robinson, Gee Ann Toh, Laure Prouvensier, Stephen Adonai Leon-Icaza, Audrey Hessel, David Péricat, Marlène S Murris, Hélène Guet-Revillet, Anthony K Henras, Julien M Buyck, Emmanuel Ravet, Franklin Lei Zhong, Céline Cougoule, Rémi Planès, Etienne Meunier
EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption. The Journal of experimental medicine 220 (10) (2023)
Tomasz Próchnicki, Matilde B Vasconcelos, Kim S Robinson, Matthew S J Mangan, Dennis M De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A Kufer, Florian Ingo Schmidt, Franklin Lei Zhong, Eicke Latz
Mitochondrial damage activates the NLRP10 inflammasome. Nature immunology (2023)
Dylan Hong Zheng Koh, Tomoki Naito, Minyoung Na, Yee Jie Yeap, Pritisha Rozario, Franklin Lei Zhong, Kah-Leong Lim, Yasunori Saheki
Visualization of accessible cholesterol using a GRAM domain-based biosensor. Nature communications 14 (1) (2023)
Kim Samirah Robinson, Gee Ann Toh, Pritisha Rozario, Rae Chua, Stefan Bauernfried, Zijin Sun, Muhammad Jasrie Firdaus, Shima Bayat, Rhea Nadkarni, Zhi Sheng Poh, Khek-Chian Tham, Cassandra R Harapas, Chrissie Kaishi Lim, Werncui Chu, Celest W S Tay, Kiat-Yi Tan, Tianyun Zhao, Carine Bonnard, Radoslaw Mikolaj Sobota, John E Connolly, John Edmund Armourer Common, Seth L Masters, Kaiwen W Chen, Lena Ho, Bin Wu, Veit Hornung, Franklin Lei Zhong
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome. Science (New York, N.Y.) 377 (6603) (2022)
Cassandra R Harapas, Kim Samirah Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott B Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D Gorrell, Sophia Davidson, Chien-Hsiung Yu, Mark Daniel Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoglu, Jean Laurent Casanova, Jonathan A Bernstein, Franklin Lei Zhong, Seth L Masters, Bruno Reversade
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling. Science immunology 7 (75) (2022)
Rhea Nadkarni, Wern Cui Chu, Cheryl Q E Lee, Yasir Mohamud, Lynn Yap, Gee Ann Toh, Sheryl Beh, Radiance Lim, Yiyun Michelle Fan, Yizhuo Lyanne Zhang, Kim Samirah Robinson, Karl Tryggvason, Honglin Luo, Franklin Lei Zhong, Lena Ho
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system. The Journal of experimental medicine 219 (10) (2022)
Menghang Huang, Xiaoxiao Zhang, Gee Ann Toh, Qin Gong, Jia Wang, Zhifu Han, Bin Wu, Franklin Lei Zhong, Jijie Chai
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9. Nature 592 (7856) (2021)
Cheryl Q E Lee, Baptiste Kerouanton, Sonia Chothani, Shan Zhang, Ying Chen, Chinmay Kumar Mantri, Daniella Helena Hock, Radiance Lim, Rhea Nadkarni, Vinh Thang Huynh, Daryl Lim, Wei Leong Chew, Franklin Lei Zhong, David Arthur Stroud, Sebastian Schafer, Vinay Tergaonkar, Ashley Lauren St John, Owen J L Rackham, Lena Ho
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity. Nature communications 12 (1) (2021)
Qin Gong, Kim Robinson, Chenrui Xu, Phuong Thao Huynh, Kelvin Han Chung Chong, Eddie Yong Jun Tan, Jiawen Zhang, Zhao Zhi Boo, Daniel Eng Thiam Teo, Kenneth Lay, Yaming Zhang, John Soon Yew Lim, Wah Ing Goh, Graham Wright, Franklin Lei Zhong, Bruno Reversade, Bin Wu
Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8. Nature communications 12 (1) (2021)
Kim Samirah Robinson, Daniel Eng Thiam Teo, Kai Sen Tan, Gee Ann Toh, Hsiao Hui Ong, Chrissie Kaishi Lim, Kenneth Lay, Bijin Veonice Au, Tian Sheng Lew, Justin Jang Hann Chu, Vincent Tak Kwong Chow, De Yun Wang, Franklin Lei Zhong, Bruno Reversade
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia. Science (New York, N.Y.) 370 (6521) (2020)
Poh Hui Chia, Franklin Lei Zhong, Shinsuke Niwa, Carine Bonnard, Kagistia Hana Utami, Ruizhu Zeng, Hane Lee, Ascia Eskin, Stanley F Nelson, William H Xie, Samah Al-Tawalbeh, Mohammad El-Khateeb, Mohammad Shboul, Mahmoud A Pouladi, Mohammed Al-Raqad, Bruno Reversade
A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability. eLife 7 (2018)

Franklin Lei Zhong.css-eqlu8i{font-size:small;padding-left:4px;} (Franklin L Zhong, Franklin Zhong)

Publication Activity (10 Years)

Top Topics

Top Venues

Franklin Lei Zhong (Franklin L Zhong, Franklin Zhong)