Seth L Masters (S L Masters)

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 55

Top Topics

Top Venues

Nature immunology

Nature communications

The Journal of experimental medicine

The EMBO journal

This page only lists publications with an associated author ORCID identifier.

Publications

Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, null null, null null, Margaret W Y Li, Carolyn Russell, Anna van Beek, Edwin P Kirk, Rebecca Walsh, Jubran Theeb Alqanatish, Abdullah Almojali, Wafaa Alsewairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E Gray, David Komander, Seth L Masters
Dominant negative OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Elina Idiiatullina, Mahmoud Al-Azab, Meng Lin, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, Caiqin Guo, Xixi Chen, Yaoying Li, Song Gao, Jun Cui, Wen-Hao Zhou, Li Liu, Yuxia Zhang, Seth L Masters
Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy. Nature communications 15 (1) (2024)
Elina Idiiatullina, Mahmoud Al-Azab, Meng Lin, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, Caiqin Guo, Xixi Chen, Yaoying Li, Song Gao, Jun Cui, Wen-Hao Zhou, Li Liu, Yuxia Zhang, Seth L Masters
Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy. Nature communications 15 (1) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, null null, null null, Margaret W Y Li, Carolyn Russell, Anna van Beek, Edwin P Kirk, Rebecca Walsh, Jubran Theeb Alqanatish, Abdullah Almojali, Wafaa Alsewairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E Gray, David Komander, Seth L Masters
Dominant negative OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, null null, null null, Margaret W Y Li, Carolyn Russell, Anna van Beek, Edwin P Kirk, Rebecca Walsh, Jubran Theeb Alqanatish, Abdullah Almojali, Wafaa Alsewairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E Gray, David Komander, Seth L Masters
Dominant negative OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, null null, null null, Margaret W Y Li, Carolyn Russell, Anna van Beek, Edwin P Kirk, Rebecca Walsh, Jubran Theeb Alqanatish, Abdullah Almojali, Wafaa Alsewairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E Gray, David Komander, Seth L Masters
Dominant negative OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Elina Idiiatullina, Mahmoud Al-Azab, Meng Lin, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, Caiqin Guo, Xixi Chen, Yaoying Li, Song Gao, Jun Cui, Wen-Hao Zhou, Li Liu, Yuxia Zhang, Seth L Masters
Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy. Nature communications 15 (1) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Author Correction: Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Sophia Davidson, Yuri Shibata, Sophie Collard, Hongyu Zheng, Klara Kong, June M Sun, Pawat Laohamonthonkul, Anthony Cerra, Tobias Kratina, null null, null null, Margaret W Y Li, Carolyn Russell, Anna van Beek, Edwin P Kirk, Rebecca Walsh, Jubran Theeb Alqanatish, Abdullah Almojali, Wafaa Alsewairi, Abdulrahman Alrasheed, Najoua Lalaoui, Paul E Gray, David Komander, Seth L Masters
Dominant negative OTULIN-related autoinflammatory syndrome. The Journal of experimental medicine 221 (6) (2024)
Mahmoud Al-Azab, Elina Idiiatullina, Ziyang Liu, Meng Lin, Katja Hrovat-Schaale, Huifang Xian, Jianheng Zhu, Mandy Yang, Bingtai Lu, Zhiyao Zhao, Yiyi Liu, Jingjie Chang, Xiaotian Li, Caiqin Guo, Yunfeng Liu, Qi Wu, Jiazhang Chen, Chaoting Lan, Ping Zeng, Jun Cui, Xia Gao, Wenhao Zhou, Yan Zhang, Yuxia Zhang, Seth L Masters
Genetic variants in UNC93B1 predispose to childhood-onset systemic lupus erythematosus. Nature immunology 25 (6) (2024)
Yaoyuan Zhang, Rhiannon Morris, Grant J Brown, Ayla May D Lorenzo, Xiangpeng Meng, Nadia J Kershaw, Pamudika Kiridena, Gaetan Burgio, Simon Gross, Jean Y Cappello, Qian Shen, Hao Wang, Cynthia Turnbull, Tom N Lea-Henry, Maurice Stanley, Zhijia Yu, Fiona D Ballard, Aaron Chuah, James C Lee, Ann-Maree Hatch, Anselm Enders, Seth L Masters, Alexander P Headley, Peter Trnka, Dominic Mallon, Jeffery T Fletcher, Giles D Walters, Mario Šestan, Marija Jelusic, Matthew C Cook, Vicki Athanasopoulos, David A Fulcher, Jeffrey J Babon, Carola G Vinuesa, Julia I Ellyard
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. The Journal of experimental medicine 221 (4) (2024)
Elina Idiiatullina, Mahmoud Al-Azab, Meng Lin, Katja Hrovat-Schaale, Ziyang Liu, Xiaotian Li, Caiqin Guo, Xixi Chen, Yaoying Li, Song Gao, Jun Cui, Wen-Hao Zhou, Li Liu, Yuxia Zhang, Seth L Masters
Heterozygous de novo dominant negative mutation of REXO2 results in interferonopathy. Nature communications 15 (1) (2024)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Elisabeth Mulazzani, Klara Kong, Juan Ignacio Aróstegui, Ashley P Ng, Nishika Ranathunga, Waruni Abeysekera, Alexandra L Garnham, Sze-Ling Ng, Paul J Baker, Jacob T Jackson, John D Lich, Margaret L Hibbs, Ian P Wicks, Cynthia Louis, Seth L Masters
G-CSF drives autoinflammation in APLAID. Nature immunology (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal (2023)
L S Tran, Le Ying, K D'Costa, G Wray-McCann, G Kerr, L Le, C C Allison, J Ferrand, H Chaudhry, J Emery, A De Paoli, Nina Colon, S Creed, Maria Kaparakis-Liaskos, J Como, Jennifer K Dowling, Priscilla Johanesen, Thomas A Kufer, J S Pedersen, Ashley Mansell, Dana J Philpott, K D Elgass, Helen E Abud, U Nachbur, Ben A Croker, Seth L Masters, Richard L Ferrero
NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nature communications 14 (1) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
L S Tran, Le Ying, K D'Costa, G Wray-McCann, G Kerr, L Le, C C Allison, J Ferrand, H Chaudhry, J Emery, A De Paoli, Nina Colon, S Creed, Maria Kaparakis-Liaskos, J Como, Jennifer K Dowling, Priscilla Johanesen, Thomas A Kufer, J S Pedersen, Ashley Mansell, Dana J Philpott, K D Elgass, Helen E Abud, U Nachbur, Ben A Croker, Seth L Masters, Richard L Ferrero
NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nature communications 14 (1) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
Seth L Masters
Ten things to know about NLRP10. Nature immunology (2023)
L S Tran, Le Ying, K D'Costa, G Wray-McCann, G Kerr, L Le, C C Allison, J Ferrand, H Chaudhry, J Emery, A De Paoli, Nina Colon, S Creed, Maria Kaparakis-Liaskos, J Como, Jennifer K Dowling, Priscilla Johanesen, Thomas A Kufer, J S Pedersen, Ashley Mansell, Dana J Philpott, K D Elgass, Helen E Abud, U Nachbur, Ben A Croker, Seth L Masters, Richard L Ferrero
NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nature communications 14 (1) (2023)
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, Ngee Kiat Chua, Jiyi Pang, Jascinta P Santavanond, Rochelle Tixeira, Marcel Doerflinger, Yexuan Deng, Chien-Hsiung Yu, Natasha Silke, Stephanie A Conos, Daniel Frank, Daniel S Simpson, James G Murphy, Kate E Lawlor, Jaclyn S Pearson, John Silke, Marc Pellegrini, Marco J Herold, Ivan K H Poon, Seth L Masters, Mingsong Li, Qin Tang, Yuxia Zhang, Maryam Rashidi, Lan-Lan Geng, James E Vince
Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency. The EMBO journal 42 (5) (2023)
L S Tran, Le Ying, K D'Costa, G Wray-McCann, G Kerr, L Le, C C Allison, J Ferrand, H Chaudhry, J Emery, A De Paoli, Nina Colon, S Creed, Maria Kaparakis-Liaskos, J Como, Jennifer K Dowling, Priscilla Johanesen, Thomas A Kufer, J S Pedersen, Ashley Mansell, Dana J Philpott, K D Elgass, Helen E Abud, U Nachbur, Ben A Croker, Seth L Masters, Richard L Ferrero
NOD1 mediates interleukin-18 processing in epithelial cells responding to Helicobacter pylori infection in mice. Nature communications 14 (1) (2023)
Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R van Eijk, Matthieu Moisse, Sali M K Farhan, Yehuda M Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy Sarah Yacovzada, Shu-Ting Hung, Johnathan Cooper-Knock, Chien-Hsiung Yu, Cynthia Louis, Seth L Masters, Kevin P Kenna, Rick A A van der Spek, William Sproviero, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Ashley R Jones, Yael Elbaz-Alon, Yahel Cohen, Elik Chapnik, Daphna Rothschild, Omer Weissbrod, Gilad Beck, Elena Ainbinder, Shifra Ben-Dor, Sebastian Werneburg, Dorothy P Schafer, Robert H Brown, Pamela J Shaw, Philip Van Damme, Leonard H van den Berg, Hemali Phatnani, Eran Segal, Justin K Ichida, Ammar Al Chalabi, Jan Herman Veldink, null null, null null, Eran Hornstein
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS. Nature neuroscience 25 (4) (2022)
Kim Samirah Robinson, Gee Ann Toh, Pritisha Rozario, Rae Chua, Stefan Bauernfried, Zijin Sun, Muhammad Jasrie Firdaus, Shima Bayat, Rhea Nadkarni, Zhi Sheng Poh, Khek-Chian Tham, Cassandra R Harapas, Chrissie Kaishi Lim, Werncui Chu, Celest W S Tay, Kiat-Yi Tan, Tianyun Zhao, Carine Bonnard, Radoslaw Mikolaj Sobota, John E Connolly, John Edmund Armourer Common, Seth L Masters, Kaiwen W Chen, Lena Ho, Bin Wu, Veit Hornung, Franklin Lei Zhong
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome. Science (New York, N.Y.) 377 (6603) (2022)
Sophia Davidson, Chien-Hsiung Yu, Annemarie Steiner, Frédéric Ebstein, Paul J Baker, Valentina Jarur-Chamy, Katja Hrovat-Schaale, Pawat Laohamonthonkul, Klara Kong, Dale J Calleja, Cassandra R Harapas, Katherine R Balka, Jacob T Mitchell, Jacob T Jackson, Niall D Geoghegan, Fiona Moghaddas, Kelly L Rogers, Katrin D Mayer-Barber, Adriana Almeida de Jesus, Dominic De Nardo, Benjamin T Kile, Anthony J Sadler, Maria Cecilia Poli, Elke Krüger, Raphaela Goldbach Mansky, Seth L Masters
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24. Science immunology 7 (68) (2022)
Cassandra R Harapas, Kim Samirah Robinson, Kenneth Lay, Jasmine Wong, Ricardo Moreno Traspas, Nasrin Nabavizadeh, Annick Rass-Rothschild, Bertrand Boisson, Scott B Drutman, Pawat Laohamonthonkul, Devon Bonner, Jingwei Rachel Xiong, Mark D Gorrell, Sophia Davidson, Chien-Hsiung Yu, Mark Daniel Fleming, Jonas Gudera, Jerry Stein, Miriam Ben-Harosh, Emily Groopman, Akiko Shimamura, Hannah Tamary, Hülya Kayserili, Nevin Hatipoglu, Jean Laurent Casanova, Jonathan A Bernstein, Franklin Lei Zhong, Seth L Masters, Bruno Reversade
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling. Science immunology 7 (75) (2022)
Annemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, Chien-Hsiung Yu, Pawat Laohamonthonkul, Cassandra R Harapas, Ronnie Ren Jie Low, Dominic De Nardo, Laura F Dagley, Michael J Mlodzianoski, Kelly L Rogers, Thomas Zillinger, Gunther Hartmann, Michael P Gantier, Marco Gattorno, Matthias Geyer, Stefano Volpi, Sophia Davidson, Seth L Masters
Deficiency in coatomer complex I causes aberrant activation of STING signalling. Nature communications 13 (1) (2022)
Cassandra R Harapas, Elina Idiiatullina, Mahmoud Al-Azab, Katja Hrovat-Schaale, Thomas Reygaerts, Annemarie Steiner, Pawat Laohamonthonkul, Sophia Davidson, Chien-Hsiung Yu, Lee M Booty, Seth L Masters
Organellar homeostasis and innate immune sensing. Nature reviews. Immunology 22 (9) (2022)
Kathy Triantafilou, Christopher J K Ward, Magdalena A Czubala, Robert G Ferris, Emma Koppe, Curt Haffner, Vincent Piguet, Vipulkumar K Patel, Heather Amrine-Madsen, Louise K Modis, Seth L Masters, Martha Triantafilou
Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages. PLoS pathogens 17 (4) (2021)
Marilou H Barrios, Alexandra L Garnham, Andrew D Foers, Lesley Cheng-Sim, Seth L Masters, Ken C Pang
Small Extracellular Vesicle Enrichment of a Retrotransposon-Derived Double-Stranded RNA: A Means to Avoid Autoinflammation? Biomedicines 9 (9) (2021)
Joanne M Hildebrand, Maria Kauppi, Ian J Majewski, Zikou Liu, Allison J Cox, Sanae Miyake, Emma J Petrie, Michael A Silk, Zhixiu Li, Maria C Tanzer, Gabriela Brumatti, Samuel N Young, Cathrine Hall, Sarah E Garnish, Jason Corbin, Michael D Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C Josefsson, Kristin Rigbye, Holly Anderton, James A Rickard, Anne Tripaydonis, Julie M Sheridan, Thomas S Scerri, Victoria E Jackson, Peter E Czabotar, Jian-Guo Zhang, Leila Varghese, Cody C Allison, Marc Pellegrini, Gillian M Tannahill, Esme C Hatchell, Tracy A Willson, Dina Stockwell, Carolyn A de Graaf, Janelle Collinge, Adrienne Hilton, Natasha Silke, Sukhdeep K Spall, Diep Chau, Vicki Athanasopoulos, Donald Metcalf, Ronald M Laxer, Alexander G Bassuk, Benjamin W Darbro, Maria A Fiatarone Singh, Nicole Vlahovich, David Hughes, Maria Kozlovskaia, David Benjamin Ascher, Klaus Warnatz, Nils Venhoff, Jens Thiel, Christine Biben, Stefan Blum, John Reveille, Michael S Hildebrand, Carola G Vinuesa, Pamela A McCombe, Matthew A Brown, Benjamin T Kile, Catriona A Mclean, Melanie Bahlo, Seth L Masters, Hiroyasu Nakano, Polly J Ferguson, James G Murphy, Warren S Alexander, John Silke
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction. Nature communications 11 (1) (2020)
Soren Riis Paludan, Thomas Pradeu, Seth L Masters, Trine H Mogensen
Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature reviews. Immunology 21 (3) (2020)
Dragana Dragoljevic, Man Kit Sam Lee, Cynthia Louis, Waled Shihata, Michael J Kraakman, Jacinta Hansen, Seth L Masters, Beatriz Y Hanaoka, Prabhakara R Nagareddy, Graeme I Lancaster, Ian P Wicks, Andrew J Murphy
Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis. Clinical & translational immunology 9 (11) (2020)
Paul J Baker, Seth L Masters
Caspase substrates won't be defined by a four-letter code. The Journal of biological chemistry 293 (18) (2019)
Tan A Nguyen, Blake R C Smith, Kirstin D Elgass, Sarah J Creed, Shane Cheung, Michelle D Tate, Gabrielle T Belz, Ian P Wicks, Seth L Masters, Ken C Pang
SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm. Journal of immunology (Baltimore, Md. : 1950) 202 (12) (2019)
Hazel Tye, Chien-Hsiung Yu, Lisa A Simms, Marcel R de Zoete, Man Lyang Kim, Martha Zakrzewski, Jocelyn Sietsma Penington, Cassandra R Harapas, Fernando Souza-Fonseca-Guimaraes, Leesa F Wockner, Adele Preaudet, Lisa A Mielke, Stephen A Wilcox, Yasunori Ogura, Sinead C Corr, Komal Kanojia, Konstantinos A Kouremenos, David P De Souza, Malcolm J McConville, Richard A Flavell, Mordechay Gerlic, Benjamin T Kile, Anthony T Papenfuss, Tracy L Putoczki, Graham L Radford-Smith, Seth L Masters
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease. Nature communications 9 (1) (2018)
Dominic De Nardo, Katherine R Balka, Yamel Cardona Gloria, Vikram R Rao, Eicke Latz, Seth L Masters
Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling. The Journal of biological chemistry 293 (39) (2018)
Franklin L Zhong, Kim Robinson, Daniel Eng Thiam Teo, Kiat-Yi Tan, Chrissie Lim, Cassandra R Harapas, Chien-Hsiung Yu, William Haowei Xie, Radoslaw M Sobota, Bijin Veonice Au, Richard Hopkins, Andrea D'Osualdo, John C Reed, John E Connolly, Seth L Masters, Bruno Reversade
Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding. The Journal of biological chemistry 293 (49) (2018)
Viola Neudecker, Moritz Haneklaus, Owen Jensen, Ludmila Khailova, Joanne C Masterson, Hazel Tye, Kathryn Biette, Paul Jedlicka, Kelley S Brodsky, Mark E Gerich, Matthias Mack, Avril A B Robertson, Matthew A Cooper, Glenn T Furuta, Charles A Dinarello, Luke A O'Neill, Holger K Eltzschig, Seth L Masters, Eoin N McNamee
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. The Journal of experimental medicine 214 (6) (2017)
Paul J Baker, Dominic De Nardo, Fiona Moghaddas, Le Son Tran, Annabell Bachem, Tan Nguyen, Thomas Hayman, Hazel Tye, James E Vince, Sammy Bedoui, Richard L Ferrero, Seth L Masters
Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition. Physiological reviews 97 (3) (2017)
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz, Daniel E Croker, Mark S Butler, Moritz Haneklaus, Caroline E Sutton, Gabriel Núñez, Eicke Latz, Daniel L Kastner, Kingston H G Mills, Seth L Masters, Kate Schroder, Matthew A Cooper, Luke A J O'Neill
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature medicine 21 (3) (2015)
Ajithkumar Vasanthakumar, Kazuyo Moro, Annie Xin, Yang Liao, Renee Gloury, Shimpei Kawamoto, Sidonia Fagarasan, Lisa A Mielke, Shoukat Afshar-Sterle, Seth L Masters, Susumu Nakae, Hirohisa Saito, John M Wentworth, Peng Li, Wei Liao, Warren J Leonard, Gordon K Smyth, Wei Shi, Stephen L Nutt, Shigeo Koyasu, Axel Kallies
The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells. Nature immunology 16 (3) (2015)