Sebastian Schafer

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 19

Top Venues

Nature

Nature communications

Clinical and experimental pharmacology & physiology

Circulation research

Duke-NUS Graduate Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Duke-NUS Graduate Medical School Sep 01 2016

Singapore

Asst. Prof. :: CVMD

National Heart Centre Singapore Dec 01 2014

Singapore

Senior Research Fellow :: NHRIS

Publications

Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature (2024)
Anissa Anindya Widjaja, Wei Wen Lim, Sivakumar Viswanathan, Sonia Chothani, Ben Corden, Cibi Mary Dasan, Joyce Wei Ting Goh, Radiance Lim, Brijesh Kumar Singh, Jessie Tan, Chee Jian Pua, Sze Yun Lim, Eleonora Adami, Sebastian Schafer, Benjamin L George, Mark Sweeney, Chen Xie, Madhulika Tripathi, Natalie A Sims, Norbert Hübner, Enrico Petretto, Dominic J Withers, Lena Ho, Jesús Gil, David Carling, Stuart Alexander Cook
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632 (8023) (2024)
Anissa Anindya Widjaja, Sivakumar Viswanathan, Shamini G Shekeran, Eleonora Adami, Wei Wen Lim, Sonia Chothani, Jessie Tan, Joyce Wei Ting Goh, Hui Mei Chen, Sze Yun Lim, Carine M Boustany-Kari, Julie Hawkins, Enrico Petretto, Norbert Hübner, Sebastian Schafer, Thomas M Coffman, Stuart Alexander Cook
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. Nature communications 13 (1) (2022)
Wei Wen Lim, Jinrui Dong, Benjamin Ng, Anissa Anindya Widjaja, Chen Xie, Liping Su, Xiu-Yi Kwek, Nicole G Z Tee, Chee Jian Pua, Sebastian Schafer, Sivakumar Viswanathan, Stuart Alexander Cook
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome. Circulation research 130 (5) (2022)
Nicola Whiffin, Konrad J Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J Smith, D Gareth Evans, Angharad M Roberts, Nicholas M Quaife, Sebastian Schafer, Owen Rackham, Jessica Alfoldi, Anne H O'Donnell-Luria, Laurent C Francioli, null null, null null, Stuart Alexander Cook, Paul J R Barton, Daniel G MacArthur, James Simon Ware
Author Correction: Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals. Nature communications 12 (1) (2021)
Jinrui Dong, Sivakumar Viswanathan, Eleonora Adami, Brijesh K Singh, Sonia P Chothani, Benjamin Ng, Wei Wen Lim, Jin Zhou, Madhulika Tripathi, Nicole S J Ko, Shamini G Shekeran, Jessie Tan, Sze Yun Lim, Mao Wang, Pei Min Lio, Paul M Yen, Sebastian Schafer, Stuart Alexander Cook, Anissa Anindya Widjaja
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH. Nature communications 12 (1) (2021)
Cheryl Q E Lee, Baptiste Kerouanton, Sonia Chothani, Shan Zhang, Ying Chen, Chinmay Kumar Mantri, Daniella Helena Hock, Radiance Lim, Rhea Nadkarni, Vinh Thang Huynh, Daryl Lim, Wei Leong Chew, Franklin Lei Zhong, David Arthur Stroud, Sebastian Schafer, Vinay Tergaonkar, Ashley Lauren St John, Owen J L Rackham, Lena Ho
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity. Nature communications 12 (1) (2021)
Wei Wen Lim, Ben Corden, Lei Ye, Sivakumar Viswanathan, Anissa Anindya Widjaja, Chen Xie, Liping Su, Nicole G Z Tee, Sebastian Schafer, Stuart Alexander Cook
Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload. Clinical and experimental pharmacology & physiology 48 (4) (2021)
Nicola Whiffin, Konrad J Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J Smith, D Gareth Evans, Angharad M Roberts, Nicholas M Quaife, Sebastian Schafer, Owen Rackham, Jessica Alfoldi, Anne H O'Donnell-Luria, Laurent C Francioli, null null, null null, Stuart Alexander Cook, Paul J R Barton, Daniel G MacArthur, James Simon Ware
Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals. Nature communications 11 (1) (2020)
Benjamin Ng, Jinrui Dong, Giuseppe Alessandro D'Agostino, Sivakumar Viswanathan, Anissa Anindya Widjaja, Wei Wen Lim, Nicole S J Ko, Jessie Tan, Sonia P Chothani, Benjamin Huang, Chen Xie, Chee Jian Pua, Ann-Marie Chacko, Nuno Guimarães-Camboa, Sylvia M Evans, Adam J Byrne, Toby M Maher, Jiurong Liang, Dianhua Jiang, Paul W Noble, Sebastian Schafer, Stuart Alexander Cook
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis. Science translational medicine 11 (511) (2020)
Huimei Chen, Aida Moreno-Moral, Francesco Pesce, Nithya Devapragash, Massimiliano Mancini, Ee Ling Heng, Maxime Rotival, Prashant K Srivastava, Nathan Harmston, Kirill Shkura, Owen J L Rackham, Wei-Ping Yu, Xi-Ming Sun, Nicole Gui Zhen Tee, Elisabeth Li Sa Tan, Paul J R Barton, Leanne E Felkin, Enrique Lara-Pezzi, Gianni Angelini, Cristina Beltrami, Michal Pravenec, Sebastian Schafer, Leonardo Bottolo, Norbert Hubner, Costanza Emanueli, Stuart Alexander Cook, Enrico Petretto
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nature communications 10 (1) (2019)
Huimei Chen, Aida Moreno-Moral, Francesco Pesce, Nithya Devapragash, Massimiliano Mancini, Ee Ling Heng, Maxime Rotival, Prashant K Srivastava, Nathan Harmston, Kirill Shkura, Owen J L Rackham, Wei-Ping Yu, Xi-Ming Sun, Nicole Gui Zhen Tee, Elisabeth Li Sa Tan, Paul J R Barton, Leanne E Felkin, Enrique Lara-Pezzi, Gianni Angelini, Cristina Beltrami, Michal Pravenec, Sebastian Schafer, Leonardo Bottolo, Norbert Hubner, Costanza Emanueli, Stuart Alexander Cook, Enrico Petretto
Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling. Nature communications 10 (1) (2019)

Sebastian Schafer.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Sebastian Schafer