Radoslaw Mikolaj Sobota (Radoslaw Sobota, Radoslaw M Sobota)

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 48

Top Venues

Nature communications

Cell death & disease

Nature cell biology

Oncogene

Agency for Science Technology and Research

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Agency for Science Technology and Research

Singapore

Principal Investigator :: Institute of Molecular and Cell Biology

Publications

Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Author Correction: METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (7) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Author Correction: METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (7) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V Grinchuk, Yajing Liang, Jayshree L Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
METTL8 links mt-tRNA m 3 C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity. Cell death & disease 15 (5) (2024)
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw Mikolaj Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications 14 (1) (2023)
Lin Yu, Xin Xu, Wan-Zhen Chua, Hao Feng, Zheng Ser, Kai Shao, Jian Shi, Yumei Wang, Zongli Li, Radoslaw Mikolaj Sobota, Lok-To Sham, Min Luo
Structural basis of peptide secretion for Quorum sensing by ComA. Nature communications 14 (1) (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology 25 (5) (2023)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Maxine S Y Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J Y Aw, Damien Zhi Ming Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw Mikolaj Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma. Nature communications 14 (1) (2023)
Maxine S Y Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J Y Aw, Damien Zhi Ming Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw Mikolaj Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma. Nature communications 14 (1) (2023)
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw Mikolaj Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications 14 (1) (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology (2023)
Shivankari Krishnananthasivam, Hao Li, Rania Bouzeyen, Bhuvaneshwari Shunmuganathan, Kiren Purushotorman, Xinlei Liao, Fengjiao Du, Claudia Guldager Kring Friis, Felicity Crawshay-Williams, Low Heng Boon, Qian Xinlei, Conrad En Zuo Chan, Radoslaw Mikolaj Sobota, Mary Kozma, Valeria Barcelli Jo, Guirong Wang, Hairong Huang, R Andres Floto, Pablo Bifani, Babak Javid, Paul Anthony MacAry
An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis. NPJ vaccines 8 (1) (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology (2023)
Maxine S Y Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J Y Aw, Damien Zhi Ming Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw Mikolaj Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma. Nature communications 14 (1) (2023)
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw Mikolaj Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications 14 (1) (2023)
Maxine S Y Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J Y Aw, Damien Zhi Ming Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw Mikolaj Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma. Nature communications 14 (1) (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology 25 (5) (2023)
Xiaosai Yao, Jing Han Hong, Amrita M Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, P Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw Mikolaj Sobota, Patrick Boon-Ooi Tan, Bin Tean Teh
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma. Nature cell biology 25 (5) (2023)
Dong Shin Park, Tatsuya Kozaki, Satish Kumar Tiwari, Marco Moreira, Ahad Khalilnezhad, Federico Torta, Nicolas Olivié, Chung Hwee Thiam, Oniko Liani, Aymeric Silvin, Wint Wint Phoo, Liang Gao, Alexander Triebl, Wai Kin Tham, Leticia Gonçalves, Wan Ting Kong, Sethi Raman, Xiao Meng Zhang, Garett Dunsmore, Charles-Antoine Dutertre, Salanne Lee, Jia Min Ong, Akhila Balachander, Shabnam Khalilnezhad, Josephine Lum, Kaibo Duan, Ze Ming Lim, Leonard Tan, Ivy Low, Kagistia Hana Utami, Xin Yi Yeo, Sylvaine Di Tommaso, Jean-William Dupuy, Balazs V Varga, Ragnhildur Thóra Káradóttir, Mufeeda Changaramvally Madathummal, Isabelle Bonne, Benoît Malleret, Zainab Yasin Binte, Ngan Wei Da, Yingrou Tan, Wei Jie Wong, Jinqiu Zhang, Jinmiao Chen, Radoslaw Mikolaj Sobota, Shanshan Wu Howland, Lai Guan Ng, Frédéric Saltel, David Castel, Jacques Grill, Veronique Minard, Salvatore Albani, Jerry K Y Chan, Morgane Sonia Thion, Sang Yong Jung, Markus R Wenk, Mahmoud A Pouladi, Claudia Pasqualini, Veronique Angeli, Olivier N F Cexus, Florent Ginhoux
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer. Nature (2023)
You Heng Chuah, Emmy Xue Yun Tay, Oleg V Grinchuk, Jeehyun Yoon, Jia Feng, Srinivasaraghavan Kannan, Matius Robert, Rekha Jakhar, Yajing Liang, Bernice Woon Li Lee, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Guang Lu, Boon Chuan Low, Karen Carmelina Crasta, Chandra Shekhar Verma, Zhewang Lin, Derrick Sek Tong Ong
CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma. Cell death and differentiation (2023)
Yu Xing Teo, Kah Yin Lee, Corinna Jie Hui Goh, Loo Chien Wang, Radoslaw Mikolaj Sobota, Keng-Hwee Chiam, Chan Du, Andrew C A Wan
Fungus-derived protein particles as cell-adhesive matrices for cell-cultivated food. NPJ science of food 7 (1) (2023)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Alex Rialdi, Mary Duffy, Alex P Scopton, Frank Fonseca, Julia Nanyi Zhao, Megan Schwarz, Pedro Molina-Sanchez, Slim Mzoughi, Elisa Arceci, Jordi Abril-Fornaguera, Austin Meadows, Marina Ruiz de Galarreta, Denis Torre, Kyna Reyes, Yan Ting Lim, Felix Rosemann, Zaigham M Khan, Kevin Mohammed, Xuedi Wang, Xufen Yu, Manikandan Lakshmanan, Ravisankar Rajarethinam, Soo Yong Tan, Jian Jin, Augusto Villanueva, Eleftherios Michailidis, Ype P De Jong, Charles M Rice, Ivan Marazzi, Dan Hasson, Josep M Llovet, Radoslaw Mikolaj Sobota, Amaia Lujambio, Ernesto Guccione, Arvin C Dar
WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma. Nature cancer (2023)
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw Mikolaj Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications 14 (1) (2023)
Teresa Lai Fong Ho, May Yin Lee, Hui Chin Goh, Germaine Yi Ning Ng, Jane Jia Hui Lee, Srinivasaraghavan Kannan, Yan Ting Lim, Tianyun Zhao, Edwin Kok Hao Lim, Cheryl Zi Jin Phua, Yi Fei Lee, Rebecca Yi Xuan Lim, Perry Jun Hao Ng, Ju Yuan, Dedrick Kok Hong Chan, Bettina Lieske, Choon Seng Chong, Kuok Chung Lee, Jeffrey Hy Lum, Wai Kit Cheong, Khay-Guan Yeoh, Ker Kan Tan, Radoslaw Mikolaj Sobota, Chandra S Verma, David P Lane, Wai Leong Tam, Ashok R Venkitaraman
Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities. Nature communications 14 (1) (2023)
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw Mikolaj Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis. Nature communications 14 (1) (2023)
Shivankari Krishnananthasivam, Hao Li, Rania Bouzeyen, Bhuvaneshwari Shunmuganathan, Kiren Purushotorman, Xinlei Liao, Fengjiao Du, Claudia Guldager Kring Friis, Felicity Crawshay-Williams, Low Heng Boon, Qian Xinlei, Conrad En Zuo Chan, Radoslaw Mikolaj Sobota, Mary Kozma, Valeria Barcelli Jo, Guirong Wang, Hairong Huang, R Andres Floto, Pablo Bifani, Babak Javid, Paul Anthony MacAry
Author Correction: An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis. NPJ vaccines 8 (1) (2023)
Maxine S Y Lam, Jose Antonio Reales-Calderon, Jin Rong Ow, Joey J Y Aw, Damien Zhi Ming Tan, Ragavi Vijayakumar, Erica Ceccarello, Tommaso Tabaglio, Yan Ting Lim, Wang Loo Chien, Fritz Lai, Anthony Tan Tanoto, Qingfeng Chen, Radoslaw Mikolaj Sobota, Giulia Adriani, Antonio Bertoletti, Ernesto Guccione, Andrea Pavesi
G9a/GLP inhibition during ex vivo lymphocyte expansion increases in vivo cytotoxicity of engineered T cells against hepatocellular carcinoma. Nature communications 14 (1) (2023)
Joleen P Z Goh, Fiorella Ruchti, Si En Poh, Winston L C Koh, Kiat-Yi Tan, Yan Ting Lim, Steven T G Thng, Radoslaw Mikolaj Sobota, Shawn S Hoon, Chenxi Liu, Anthony J O'Donoghue, Salomé LeibundGut-Landmann, Hazel Hweeboon Oon, Hao Li, Thomas L Dawson
The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation. Proceedings of the National Academy of Sciences of the United States of America 119 (49) (2022)
Kim Samirah Robinson, Gee Ann Toh, Pritisha Rozario, Rae Chua, Stefan Bauernfried, Zijin Sun, Muhammad Jasrie Firdaus, Shima Bayat, Rhea Nadkarni, Zhi Sheng Poh, Khek-Chian Tham, Cassandra R Harapas, Chrissie Kaishi Lim, Werncui Chu, Celest W S Tay, Kiat-Yi Tan, Tianyun Zhao, Carine Bonnard, Radoslaw Mikolaj Sobota, John E Connolly, John Edmund Armourer Common, Seth L Masters, Kaiwen W Chen, Lena Ho, Bin Wu, Veit Hornung, Franklin Lei Zhong
ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome. Science (New York, N.Y.) 377 (6603) (2022)
Marjan Abbasi, Alexander Julner, Yan Ting Lim, Tianyun Zhao, Radoslaw Mikolaj Sobota, Victoria Menéndez-Benito
Phosphosites of the yeast centrosome component Spc110 contribute to cell cycle progression and mitotic exit. Biology open 11 (11) (2022)
Sharanjeet Atwal, Jantana Wongsantichon, Suparat Giengkam, Kittirat Saharat, Yanin Jaiyen Pittayasathornthun, Suthida Chuenklin, Loo Chien Wang, Taerin Chung, Hyun Huh, Sang-Hyuk Lee, Radoslaw Mikolaj Sobota, Jeanne Salje
The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state. Nature communications 13 (1) (2022)
Xavier Bisteau, Joann Lee, Vinayaka Srinivas, Joanna H S Lee, Joanna Niska-Blakie, Gifford Tan, Shannon Y X Yap, Kevin W Hom, Cheng Kit Wong, Jeongjun Chae, Loo Chien Wang, Jinho Kim, Giulia Rancati, Radoslaw Mikolaj Sobota, Chris S H Tan, Philipp Kaldis
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis. Oncogene 39 (44) (2020)
Bozena Mika-Gospodorz, Suparat Giengkam, Alexander J Westermann, Jantana Wongsantichon, Willow Kion-Crosby, Suthida Chuenklin, Loo Chien Wang, Piyanate Sunyakumthorn, Radoslaw Mikolaj Sobota, Selvakumar Subbian, Jörg Vogel, Lars Barquist, Jeanne Salje
Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen. Nature communications 11 (1) (2020)
Shan Zhang, Boris Reljić, Chao Liang, Baptiste Kerouanton, Joel Celio Francisco, Jih Hou Peh, Camille Mary, Narendra Suhas Jagannathan, Volodimir Olexiouk, Claire Tang, Gio Fidelito, Srikanth Nama, Ruey-Kuang Cheng, Caroline Lei Wee, Loo Chien Wang, Paula Duek Roggli, Prabha Sampath, Lydie Lane, Enrico Petretto, Radoslaw Mikolaj Sobota, Suresh J Jesuthasan, Lisa Tucker-Kellogg, Bruno Reversade, Gerben Menschaert, Lei Sun, David Arthur Stroud, Lena Ho
Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly. Nature communications 11 (1) (2020)
Jerzy Michal Dziekan, Grennady Wirjanata, Lingyun Dai, Ka Diam Go, Han Yu, Yan Ting Lim, Liyan Chen, Loo Chien Wang, Brenda Puspita, Nayana Prabhu, Radoslaw Mikolaj Sobota, Pär Nordlund, Zbynek Bozdech
Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome. Nature protocols 15 (6) (2020)
Jerzy Michal Dziekan, Han Yu, Dan Chen, Lingyun Dai, Grennady Wirjanata, Andreas Larsson, Nayana Prabhu, Radoslaw Mikolaj Sobota, Zbynek Bozdech, Pär Nordlund
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay. Science translational medicine 11 (473) (2020)
Qun Zeng, Ye Mon Soe, Yanting Lim, Radoslaw Mikolaj Sobota, Herbert Schwarz
CD137 ligand interacts with CD32a to trigger reverse CD137 ligand signaling. Cellular & molecular immunology 17 (11) (2020)
Nathan Palmer, S Zakiah A Talib, Chandrahas Koumar Ratnacaram, Diana Low, Xavier Bisteau, Joanna Hui Si Lee, Elisabeth Pfeiffenberger, Heike Wollmann, Joel Heng Loong Tan, Sheena Wee, Radoslaw Mikolaj Sobota, Jayantha Gunaratne, Daniel M Messerschmidt, Ernesto Guccione, Philipp Kaldis
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I. The Journal of cell biology 218 (9) (2019)
Chee-Wai Wong, Catherine F LeGrand, Beverley F Kinnear, Radoslaw Mikolaj Sobota, Rajkumar Ramalingam, Danielle E Dye, Michael Raghunath, E Birgitte Lane, Deirdre R Coombe
In Vitro Expansion of Keratinocytes on Human Dermal Fibroblast-Derived Matrix Retains Their Stem-Like Characteristics. Scientific reports 9 (1) (2019)
Matae Ahn, Danielle E Anderson, Qian Zhang, Chee Wah Tan, Beng Lee Lim, Katarina Luko, Ming Wen, Wan Ni Chia, Shailendra Mani, Loo Chien Wang, Justin Han Jia Ng, Radoslaw Mikolaj Sobota, Charles-Antoine Dutertre, Florent Ginhoux, Zheng-Li Shi, Aaron Trent Irving, Lin-Fa Wang
Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host. Nature microbiology 4 (5) (2019)
Weimei Ruan, Gireedhar Venkatachalam, Radoslaw Mikolaj Sobota, Liyan Chen, Loo Chien Wang, Alena Jacobson, Kathirvel Paramasivam, Uttam Surana
Resistance to anti-microtubule drug-induced cell death is determined by regulation of BimEL expression. Oncogene 38 (22) (2019)

Radoslaw Mikolaj Sobota.css-eqlu8i{font-size:small;padding-left:4px;} (Radoslaw Sobota, Radoslaw M Sobota)

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Radoslaw Mikolaj Sobota (Radoslaw Sobota, Radoslaw M Sobota)