Franz-Josef Meyer-Almes

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 30

Top Topics

Structure Activity Relationship

Dna Methylation

Histone Deacetylase

Top Venues

Journal of medicinal chemistry

International journal of molecular sciences

Chemistry (Weinheim an der Bergstrasse, Germany)

Protein science : a publication of the Protein Society

This page only lists publications with an associated author ORCID identifier.

Publications

Aleksandra Kopranovic, Franz-Josef Meyer-Almes
Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8. International journal of molecular sciences 25 (11) (2024)
Annika Lill, Markus Schweipert, Thomas Nehls, Eva Wurster, Frederik Lermyte, Franz-Josef Meyer-Almes, Katja Schmitz
Design and synthesis of peptides as stabilizers of histone deacetylase 4. Journal of peptide science : an official publication of the European Peptide Society 30 (9) (2024)
Markus Schweipert, Thomas Nehls, Anton Frühauf, Cecilé Debarnot, Adarsh Kumar, Stefan Knapp, Frederik Lermyte, Franz-Josef Meyer-Almes
The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation. Protein science : a publication of the Protein Society 33 (3) (2024)
Annika Lill, Markus Schweipert, Thomas Nehls, Eva Wurster, Frederik Lermyte, Franz-Josef Meyer-Almes, Katja Schmitz
Design and synthesis of peptides as stabilizers of histone deacetylase 4. Journal of peptide science : an official publication of the European Peptide Society (2024)
Aleksandra Kopranovic, Franz-Josef Meyer-Almes
Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8. International journal of molecular sciences 25 (11) (2024)
Aleksandra Kopranovic, Franz-Josef Meyer-Almes
Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8. International journal of molecular sciences 25 (11) (2024)
Markus Schweipert, Thomas Nehls, Anton Frühauf, Cecilé Debarnot, Adarsh Kumar, Stefan Knapp, Frederik Lermyte, Franz-Josef Meyer-Almes
The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation. Protein science : a publication of the Protein Society 33 (3) (2024)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry (2023)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry 67 (1) (2023)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry 67 (1) (2023)
Markus Schweipert, Anuja Amurthavasan, Franz-Josef Meyer-Almes
Continuous enzyme activity assay for high-throughput classification of histone deacetylase 8 inhibitors. Exploration of targeted anti-tumor therapy 4 (3) (2023)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry 67 (1) (2023)
Anton Frühauf, Martin Behringer, Franz-Josef Meyer-Almes
Significance of Five-Membered Heterocycles in Human Histone Deacetylase Inhibitors. Molecules (Basel, Switzerland) 28 (15) (2023)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry 67 (1) (2023)
Yogesh Mahadu Khetmalis, Ashna Fathima, Markus Schweipert, Cécile Debarnot, Naga Venkata Madhusudhan Rao Bandaru, Sankaranarayanan Murugesan, Trinath Jamma, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar
Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity. International journal of molecular sciences 24 (13) (2023)
Aaron B Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, György Miklós Keserű
Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. Journal of medicinal chemistry 67 (1) (2023)
Niklas Jänsch, Anton Frühauf, Markus Schweipert, Cécile Debarnot, Miriam Erhardt, Gerald Brenner-Weiss, Frank Kirschhöfer, Tomas Jasionis, Edita Čapkauskaitė, Asta Zubrienė, Daumantas Matulis, Franz-Josef Meyer-Almes
3-Chloro-5-Substituted-1,2,4-Thiadiazoles (TDZs) as Selective and Efficient Protein Thiol Modifiers. Chembiochem : a European journal of chemical biology 23 (21) (2022)
Virginija Jakubkiene, Gabrielius Ernis Valiulis, Markus Schweipert, Asta Zubrienė, Daumantas Matulis, Franz-Josef Meyer-Almes, Sigitas Tumkevičius
Synthesis and HDAC inhibitory activity of pyrimidine-based hydroxamic acids. Beilstein journal of organic chemistry 18 (2022)
Niklas Jänsch, Kim Leoni Lang, Franz-Josef Meyer-Almes
Methionine 274 Is Not the Determining Factor for Selective Inhibition of Histone Deacetylase 8 (HDAC8) by L-Shaped Inhibitors. International journal of molecular sciences 23 (19) (2022)
Kalpana Tilekar, Jessica D Hess, Neha Upadhyay, Alessandra Lo Bianco, Markus Schweipert, Antonio Laghezza, Fulvio Loiodice, Franz-Josef Meyer-Almes, Renato J Aguilera, Antonio Lavecchia, Ramaa C S
Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPARγ and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. Journal of medicinal chemistry 64 (10) (2021)
Neha Upadhyay, Kalpana Tilekar, Sabreena Safuan, Alan Prem Kumar, Markus Schweipert, Franz-Josef Meyer-Almes, Ramaa C S
Multi-target weapons: diaryl-pyrazoline thiazolidinediones simultaneously targeting VEGFR-2 and HDAC cancer hallmarks. RSC medicinal chemistry 12 (9) (2021)
Martin Spinck, Matthias Bischoff, Philipp Lampe, Franz-Josef Meyer-Almes, Sonja Sievers, Heinz Neumann
Discovery of Dihydro-1,4-Benzoxazine Carboxamides as Potent and Highly Selective Inhibitors of Sirtuin-1. Journal of medicinal chemistry 64 (9) (2021)
Markus Schweipert, Niklas Jänsch, Neha Upadhyay, Kalpana Tilekar, Ewelina Wozny, Sidra Basheer, Eva Wurster, Marlene Müller, Ramaa C S, Franz-Josef Meyer-Almes
Mechanistic Insights into Binding of Ligands with Thiazolidinedione Warhead to Human Histone Deacetylase 4. Pharmaceuticals (Basel, Switzerland) 14 (10) (2021)
Anton Frühauf, Franz-Josef Meyer-Almes
Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases. Molecules (Basel, Switzerland) 26 (17) (2021)
Niklas Jänsch, Wisely Oki Sugiarto, Marius Muth, Aleksandra Kopranovic, Charlotte Desczyk, Matthias Ballweg, Frank Kirschhöfer, Gerald Brenner-Weiss, Franz-Josef Meyer-Almes
Switching the Switch: Ligand Induced Disulfide Formation in HDAC8. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (58) (2020)
Wei Tan, Niklas Jänsch, Tina Öhlmann, Franz-Josef Meyer-Almes, Xuefeng Jiang
Thiocarbonyl Surrogate via Combination of Potassium Sulfide and Chloroform for Dithiocarbamate Construction. Organic letters 21 (18) (2019)
Franz-Josef Meyer-Almes
Determination of the binding mechanism of histone deacetylase inhibitors. Chemical biology & drug design 93 (6) (2018)
Christian Meyners, Monique Mertens, Pablo Wessig, Franz-Josef Meyer-Almes
A Fluorescence-Lifetime-Based Binding Assay for Class IIa Histone Deacetylases. Chemistry (Weinheim an der Bergstrasse, Germany) 23 (13) (2017)
Christian Meyners, Franz-Josef Meyer-Almes
Impact of binding mechanism on selective inhibition of histone deacetylase isoforms. Chemical biology & drug design 90 (6) (2017)
Alexander Kleinschek, Christian Meyners, Eros Digiorgio, Claudio Brancolini, Franz-Josef Meyer-Almes
Potent and Selective Non-hydroxamate Histone Deacetylase 8 Inhibitors. ChemMedChem 11 (23) (2016)