Antonio Laghezza

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 30

Top Topics

Molecular Dynamics Simulations

Machine Learning

Top Venues

Journal of medicinal chemistry

Molecular pharmaceutics

Scientific reports

This page only lists publications with an associated author ORCID identifier.

Publications

Davide Capelli, Giulia Cazzaniga, Matteo Mori, Antonio Laghezza, Fulvio Loiodice, Martina Quaglia, Elisa Negro, Fiorella Meneghetti, Stefania Villa, Roberta Montanari
Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition. Biomolecules 13 (4) (2023)
Maria Cristina Lomuscio, Carmen Abate, Domenico Alberga, Antonio Laghezza, Nicola Corriero, Nicola Antonio Colabufo, Alessandro Tossi, Pietro Delre, Giuseppe Felice Mangiatordi
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis. Molecular pharmaceutics (2023)
Davide Capelli, Giulia Cazzaniga, Matteo Mori, Antonio Laghezza, Fulvio Loiodice, Martina Quaglia, Elisa Negro, Fiorella Meneghetti, Stefania Villa, Roberta Montanari
Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition. Biomolecules 13 (4) (2023)
Maria Cristina Lomuscio, Carmen Abate, Domenico Alberga, Antonio Laghezza, Nicola Corriero, Nicola Antonio Colabufo, Alessandro Tossi, Pietro Delre, Giuseppe Felice Mangiatordi
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis. Molecular pharmaceutics 21 (2) (2023)
Maria Cristina Lomuscio, Carmen Abate, Domenico Alberga, Antonio Laghezza, Nicola Corriero, Nicola Antonio Colabufo, Alessandro Tossi, Pietro Delre, Giuseppe Felice Mangiatordi
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis. Molecular pharmaceutics 21 (2) (2023)
Antonio Laghezza, Carmen Cerchia, Massimo Genovese, Rosalba Leuci, Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, Abanish Biswas, Ravi Pratap Singh, Suhas Tambe, Sudeep Ca, Ashok Kumar Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition. Journal of medicinal chemistry 66 (5) (2023)
Antonio Laghezza, Carmen Cerchia, Massimo Genovese, Rosalba Leuci, Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, Abanish Biswas, Ravi Pratap Singh, Suhas Tambe, Sudeep Ca, Ashok Kumar Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition. Journal of medicinal chemistry (2023)
Antonio Laghezza, Carmen Cerchia, Massimo Genovese, Rosalba Leuci, Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, Abanish Biswas, Ravi Pratap Singh, Suhas Tambe, Sudeep Ca, Ashok Kumar Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition. Journal of medicinal chemistry 66 (5) (2023)
Antonio Laghezza, Carmen Cerchia, Massimo Genovese, Rosalba Leuci, Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, Abanish Biswas, Ravi Pratap Singh, Suhas Tambe, Sudeep Ca, Ashok Kumar Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition. Journal of medicinal chemistry 66 (5) (2023)
Antonio Laghezza, Carmen Cerchia, Massimo Genovese, Rosalba Leuci, Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, Abanish Biswas, Ravi Pratap Singh, Suhas Tambe, Sudeep Ca, Ashok Kumar Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice
A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition. Journal of medicinal chemistry (2023)
Maria Cristina Lomuscio, Carmen Abate, Domenico Alberga, Antonio Laghezza, Nicola Corriero, Nicola Antonio Colabufo, Alessandro Tossi, Pietro Delre, Giuseppe Felice Mangiatordi
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis. Molecular pharmaceutics 21 (2) (2023)
Maria Cristina Lomuscio, Carmen Abate, Domenico Alberga, Antonio Laghezza, Nicola Corriero, Nicola Antonio Colabufo, Alessandro Tossi, Pietro Delre, Giuseppe Felice Mangiatordi
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis. Molecular pharmaceutics 21 (2) (2023)
Davide Capelli, Giulia Cazzaniga, Matteo Mori, Antonio Laghezza, Fulvio Loiodice, Martina Quaglia, Elisa Negro, Fiorella Meneghetti, Stefania Villa, Roberta Montanari
Biological Screening and Crystallographic Studies of Hydroxy γ-Lactone Derivatives to Investigate PPARγ Phosphorylation Inhibition. Biomolecules 13 (4) (2023)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Alessia Carocci, Alexia Barbarossa, Rosalba Leuci, Antonio Carrieri, Leonardo Brunetti, Antonio Laghezza, Marco Catto, Francesco Limongelli, Silvia Chaves, Paolo Tortorella, Cosimo Damiano Altomare, Maria Amélia Santos, Fulvio Loiodice, Luca Piemontese
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease. Antioxidants (Basel, Switzerland) 11 (9) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry (2022)
Rosalba Leuci, Leonardo Brunetti, Antonio Laghezza, Luca Piemontese, Antonio Carrieri, Leonardo Pisani, Paolo Tortorella, Marco Catto, Fulvio Loiodice
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE). Molecules (Basel, Switzerland) 27 (3) (2022)
Francesca Intranuovo, Leonardo Brunetti, Pietro DelRe, Giuseppe Felice Mangiatordi, Angela Stefanachi, Antonio Laghezza, Mauro Niso, Francesco Leonetti, Fulvio Loiodice, Alessia Ligresti, Magdalena Kostrzewa, Jose Brea, Maria Isabel Loza, Eddy Sotelo, Alessandro Tossi, Nicola Antonio Colabufo, Chiara Riganti, Carmen Abate, Marialessandra Contino
Development of N -(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase. Journal of medicinal chemistry 66 (1) (2022)
Kalpana Tilekar, Jessica D Hess, Neha Upadhyay, Alessandra Lo Bianco, Markus Schweipert, Antonio Laghezza, Fulvio Loiodice, Franz-Josef Meyer-Almes, Renato J Aguilera, Antonio Lavecchia, Ramaa C S
Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPARγ and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. Journal of medicinal chemistry 64 (10) (2021)
Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, Alessia Caradonna, Mariangela Agamennone, Fulvio Loiodice, Paolo Tortorella
(2-Aminobenzothiazole)-Methyl-1,1-Bisphosphonic Acids: Targeting Matrix Metalloproteinase 13 Inhibition to the Bone. Pharmaceuticals (Basel, Switzerland) 14 (2) (2021)
Viviana Poliseno, Sílvia Chaves, Leonardo Brunetti, Fulvio Loiodice, Antonio Carrieri, Antonio Laghezza, Paolo Tortorella, João D Magalhães, Sandra M Cardoso, Maria Amélia Santos, Luca Piemontese
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease Agents. Biomolecules 11 (1) (2021)
Leonardo Brunetti, Antonio Carrieri, Luca Piemontese, Paolo Tortorella, Fulvio Loiodice, Antonio Laghezza
Beyond the Canonical Endocannabinoid System. A Screening of PPAR Ligands as FAAH Inhibitors. International journal of molecular sciences 21 (19) (2020)
Rosalba Leuci, Leonardo Brunetti, Viviana Poliseno, Antonio Laghezza, Fulvio Loiodice, Paolo Tortorella, Luca Piemontese
Natural Compounds for the Prevention and Treatment of Cardiovascular and Neurodegenerative Diseases. Foods (Basel, Switzerland) 10 (1) (2020)
Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, Alessia Caradonna, Mariangela Agamennone, Antonella Di Pizio, Giorgio Pochetti, Roberta Montanari, Davide Capelli, Marilena Tauro, Fulvio Loiodice, Paolo Tortorella
Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy. Pharmaceuticals (Basel, Switzerland) 13 (6) (2020)
Leonardo Brunetti, Fulvio Loiodice, Luca Piemontese, Paolo Tortorella, Antonio Laghezza
New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation. Journal of medicinal chemistry 62 (24) (2019)
Luca Piemontese, Gabriele Vitucci, Marco Catto, Antonio Laghezza, Filippo Maria Perna, Mariagrazia Rullo, Fulvio Loiodice, Alejandro Presa Soto, Michele Solfrizzo
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer's Disease. Molecules (Basel, Switzerland) 23 (9) (2018)
Sabina Yasmin, Fabio Capone, Antonio Laghezza, Fabrizio Dal Piaz, Fulvio Loiodice, Viswanathan Vijayan, Velmurugan Devadasan, Susanta K Mondal, Özlem Atlı, Merve Baysal, Ashok K Pattnaik, Venkatesan Jayaprakash, Antonio Lavecchia
Novel Benzylidene Thiazolidinedione Derivatives as Partial PPARγ Agonists and their Antidiabetic Effects on Type 2 Diabetes. Scientific reports 7 (1) (2017)
Gloria Brusotti, Roberta Montanari, Davide Capelli, Giulia Cattaneo, Antonio Laghezza, Paolo Tortorella, Fulvio Loiodice, Franck Peiretti, Bernadette Bonardo, Alessandro Paiardini, Enrica Calleri, Giorgio Pochetti
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis. Scientific reports 7 (1) (2017)
Grazia Luisi, Guido Angelini, Carla Gasbarri, Antonio Laghezza, Mariangela Agamennone, Fulvio Loiodice, Claudiu T Supuran, Cristina Campestre, Paolo Tortorella
Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids. Journal of enzyme inhibition and medicinal chemistry 32 (1) (2017)