Gregory R Bowman (Greg R Bowman, Gregory Bowman, G R Bowman)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 51

Top Topics

Molecular Dynamics Simulations

Hypertrophic Cardiomyopathy

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Journal of chemical theory and computation

The journal of physical chemistry. B

This page only lists publications with an associated author ORCID identifier.

Publications

Meghana Kshirsagar, Artur Meller, Ian Humphreys, Samuel Sledzieski, Yixi Xu, Rahul Dodhia, Eric Horvitz, Bonnie Berger, Gregory R Bowman, Juan Lavista Ferres, Julien S Baker, Minkyung Baek
Rapid and accurate prediction of protein homo-oligomer symmetry with Seq2Symm. Research square (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation (2024)
Justin J Miller, Upasana L Mallimadugula, Maxwell I Zimmerman, Melissa D Stuchell-Brereton, Andrea Soranno, Gregory R Bowman
Accounting for fast vs slow exchange in single molecule FRET experiments reveals hidden conformational states. bioRxiv : the preprint server for biology (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B 128 (15) (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B 128 (15) (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation 20 (3) (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Justin J Miller, Upasana L Mallimadugula, Maxwell I Zimmerman, Melissa D Stuchell-Brereton, Andrea Soranno, Gregory R Bowman
Accounting for fast vs slow exchange in single molecule FRET experiments reveals hidden conformational states. bioRxiv : the preprint server for biology (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B (2024)
Tyson D Todd, Neha Vithani, Sukrit Singh, Gregory R Bowman, Kendall J Blumer, Andrea Soranno
Stabilization of interdomain closure by a G protein inhibitor. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation 20 (3) (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation 20 (3) (2024)
Chao Liu, Anastasia Karabina, Artur Meller, Ayan Bhattacharjee, Colby J Agostino, Gregory R Bowman, Kathleen M Ruppel, James A Spudich, Leslie A Leinwand
Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation. Proceedings of the National Academy of Sciences of the United States of America 121 (9) (2024)
Meghana Kshirsagar, Artur Meller, Ian Humphreys, Samuel Sledzieski, Yixi Xu, Rahul Dodhia, Eric Horvitz, Bonnie Berger, Gregory R Bowman, Juan Lavista Ferres, Julien S Baker, Minkyung Baek
Rapid and accurate prediction of protein homo-oligomer symmetry with Seq2Symm. Research square (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B 128 (15) (2024)
Louis G Smith, Borna Novak, Meghan Osato, David L Mobley, Gregory R Bowman
PopShift: A Thermodynamically Sound Approach to Estimate Binding Free Energies by Accounting for Ligand-Induced Population Shifts from a Ligand-Free Markov State Model. Journal of chemical theory and computation 20 (3) (2024)
Tyson D Todd, Neha Vithani, Sukrit Singh, Gregory R Bowman, Kendall J Blumer, Andrea Soranno
Stabilization of interdomain closure by a G protein inhibitor. Proceedings of the National Academy of Sciences of the United States of America 121 (36) (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B 128 (15) (2024)
Neha Vithani, Tyson D Todd, Sukrit Singh, Tony Trent, Kendall J Blumer, Gregory R Bowman
G Protein Activation Occurs via a Largely Universal Mechanism. The journal of physical chemistry. B 128 (15) (2024)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Soumendranath Bhakat, Shahlo Solieva, Gregory R Bowman
Accelerating Cryptic Pocket Discovery Using AlphaFold. Journal of chemical theory and computation (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Michael Ward, Jonathan Borowsky, Meghana Kshirsagar, Jeffrey M Lotthammer, Felipe Oviedo, Juan M Lavista Ferres, Gregory R Bowman
Predicting locations of cryptic pockets from single protein structures using the PocketMiner graph neural network. Nature communications 14 (1) (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Michael Ward, Jonathan Borowsky, Meghana Kshirsagar, Jeffrey M Lotthammer, Felipe Oviedo, Juan M Lavista Ferres, Gregory R Bowman
Predicting locations of cryptic pockets from single protein structures using the PocketMiner graph neural network. Nature communications 14 (1) (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, Gregory R Bowman
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains. eLife 12 (2023)
Artur Meller, Saulo de Oliveira, Aram Davtyan, Tigran M Abramyan, Gregory R Bowman, Henry van den Bedem
Discovery of a cryptic pocket in the AI-predicted structure of PPM1D phosphatase explains the binding site and potency of its allosteric inhibitors. bioRxiv : the preprint server for biology (2023)
Artur Meller, Michael Ward, Jonathan Borowsky, Meghana Kshirsagar, Jeffrey M Lotthammer, Felipe Oviedo, Juan M Lavista Ferres, Gregory R Bowman
Predicting locations of cryptic pockets from single protein structures using the PocketMiner graph neural network. Nature communications 14 (1) (2023)
Matthew A Cruz, Thomas E Frederick, Upasana L Mallimadugula, Sukrit Singh, Neha Vithani, Maxwell I Zimmerman, Justin R Porter, Katelyn E Moeder, Gaya K Amarasinghe, Gregory R Bowman
A cryptic pocket in Ebola VP35 allosterically controls RNA binding. Nature communications 13 (1) (2022)
David A Agard, Gregory R Bowman, William F DeGrado, Nikolay V Dokholyan, Huan-Xiang Zhou
Solution of the protein structure prediction problem at last: crucial innovations and next frontiers. Faculty reviews 11 (2022)
Zhou Huang, Hejun Liu, Jay C Nix, Rui Xu, Catherine R Knoverek, Gregory R Bowman, Gaya K Amarasinghe, L David Sibley
The intrinsically disordered protein TgIST from Toxoplasma gondii inhibits STAT1 signaling by blocking cofactor recruitment. Nature communications 13 (1) (2022)
David A Agard, Gregory R Bowman, William F DeGrado, Nikolay V Dokholyan, Huan-Xiang Zhou
Solution of the protein structure prediction problem at last: crucial innovations and next frontiers. Faculty reviews 11 (2022)
Manasi Malik, Michael D Ward, Yingye Fang, Justin R Porter, Maxwell I Zimmerman, Thomas Koelblen, Michelle Roh, Antonina I Frolova, Thomas P Burris, Gregory R Bowman, Princess I Imoukhuede, Sarah K England
Naturally Occurring Genetic Variants in the Oxytocin Receptor Alter Receptor Signaling Profiles. ACS pharmacology & translational science 4 (5) (2021)
Catherine R Knoverek, Upasana L Mallimadugula, Sukrit Singh, Enrico Rennella, Thomas E Frederick, Tairan Yuwen, Shreya Raavicharla, Lewis E Kay, Gregory R Bowman
Opening of a cryptic pocket in β-lactamase increases penicillinase activity. Proceedings of the National Academy of Sciences of the United States of America 118 (47) (2021)
Maxwell I Zimmerman, Justin R Porter, Michael D Ward, Sukrit Singh, Neha Vithani, Artur Meller, Upasana L Mallimadugula, Catherine E Kuhn, Jonathan H Borowsky, Rafal P Wiewiora, Matthew F D Hurley, Aoife M Harbison, Carl A Fogarty, Joseph E Coffland, Elisa Fadda, Vincent A Voelz, John D Chodera, Gregory R Bowman
SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome. Nature chemistry 13 (7) (2021)
Jessica B Behring, Sjoerd van der Post, Arshag D Mooradian, Matthew J Egan, Maxwell I Zimmerman, Jenna L Clements, Gregory R Bowman, Jason M Held
Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation. Science signaling 13 (615) (2020)
Justin R Porter, Artur Meller, Maxwell I Zimmerman, Michael J Greenberg, Gregory R Bowman
Conformational distributions of isolated myosin motor domains encode their mechanochemical properties. eLife 9 (2020)
Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Sukrit Singh, Melissa D Stuchell-Brereton, Michael D Ward, Maxwell I Zimmerman, Neha Vithani, Daniel Griffith, Jason A Wagoner, Gregory R Bowman, Kathleen B Hall, Andrea Soranno, Alex S Holehouse
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA. bioRxiv : the preprint server for biology (2020)
Justin R Porter, M I Zimmerman, Gregory R Bowman
Enspara: Modeling molecular ensembles with scalable data structures and parallel computing. The Journal of chemical physics 150 (4) (2019)
Xianqiang Sun, Sukrit Singh, Kendall J Blumer, Gregory R Bowman
Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding. eLife 7 (2018)
Haixia Niu, Hideji Fujiwara, Orsola di Martino, Gayla Hadwiger, Thomas E Frederick, María Piedad Menéndez-Gutiérrez, Mercedes Ricote, Gregory R Bowman, John S S Welch
Endogenous retinoid X receptor ligands in mouse hematopoietic cells. Science signaling 10 (503) (2017)
Gregory R Bowman
Accurately modeling nanosecond protein dynamics requires at least microseconds of simulation. Journal of computational chemistry 37 (6) (2015)