Geert van Loo (Geert Van Loo)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 42

Top Topics

Induced Apoptosis

Top Venues

Cell death & disease

Science (New York, N.Y.)

The Journal of experimental medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Martijn J Schuijs, Claudia M Brenis Gomez, Fabian Bick, Justine Van Moorleghem, Manon Vanheerswynghels, Geert van Loo, Rudi Beyaert, David Vöhringer, Richard M Locksley, Hamida Hammad, Bart N Lambrecht
Interleukin-33-activated basophils promote asthma by regulating Th2 cell entry into lung tissue. The Journal of experimental medicine 221 (12) (2024)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
M Giulia Doglio, Lien Verboom, Emily Ruilova Sosoranga, Ulrika C Frising, Tomoko Asaoka, Yannick Gansemans, Filip Van Nieuwerburgh, Geert van Loo, Andy Wullaert
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion. Science immunology 8 (89) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Lien Verboom, Christopher J Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi S Ravichandran, Lars Vereecke, Geert van Loo
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection. Cell death & disease 14 (8) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Alexandra Thiran, Ioanna Petta, Gillian Blancke, Marie Thorp, Guillaume Planckaert, Maude Jans, Vanessa Andries, Korneel Barbry, Elisabeth Gilis, Julie Coudenys, Tino Hochepied, Christian Vanhove, Eric Gracey, Emilie Dumas, Teddy Manuelo, Ivan Josipovic, Geert van Loo, Dirk Elewaut, Lars Vereecke
Sterile triggers drive joint inflammation in TNF- and IL-1β-dependent mouse arthritis models. EMBO molecular medicine (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Emily Van San, Angela C Debruyne, Geraldine Veeckmans, Yulia Y Tyurina, Vladimir A Tyurin, Hao Zheng, Sze Men Choi, Koen Augustyns, Geert van Loo, Bernhard Michalke, Vivek Venkataramani, Shinya Toyokuni, Hülya Bayır, Peter Vandenabeele, Behrouz Hassannia, Tom Vanden Berghe
Ferroptosis contributes to multiple sclerosis and its pharmacological targeting suppresses experimental disease progression. Cell death and differentiation (2023)
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection. Cell death & disease 14 (4) (2023)
Peng Xiao, Tatiana Takiishi, Natalia Moretti Violato, Giada Licata, Francesco Dotta, Guido Sebastiani, Lorella Marselli, Sumeet Pal Singh, Mozes Sze, Geert van Loo, Emmanuel Dejardin, Esteban Nicolas Gurzov, Alessandra Kupper Cardozo
NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes. Cell death & disease 13 (5) (2022)
Sophia Maschalidi, Parul Mehrotra, Burcu N Keçeli, Hannah K L De Cleene, Kim Lecomte, Renée Van der Cruyssen, Pauline Janssen, Jonathan Pinney, Geert van Loo, Dirk Elewaut, Ann Massie, Esther Hoste, Kodi S Ravichandran
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes. Nature 606 (7915) (2022)
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J M Bertrand
ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway. Science (New York, N.Y.) 378 (6625) (2022)
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J M Bertrand
ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway. Science (New York, N.Y.) 378 (6625) (2022)
Richard de Reuver, Simon Verdonck, Evelien Dierick, Josephine Nemegeer, Eline Hessmann, Sadeem Ahmad, Maude Jans, Gillian Blancke, Filip Van Nieuwerburgh, Alexander Botzki, Lars Vereecke, Geert van Loo, Wim Declercq, Sun Hur, Peter Vandenabeele, Jonathan Maelfait
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation. Nature 607 (7920) (2022)
Ulrika C Frising, Silvia Ribo, M Giulia Doglio, Bernard Malissen, Geert van Loo, Andy Wullaert
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice. EMBO reports 23 (7) (2022)
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J M Bertrand
ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway. Science (New York, N.Y.) 378 (6625) (2022)
Jon Huyghe, Dario Priem, Lisette Van Hove, Barbara Gilbert, Jürgen Fritsch, Yasuo Uchiyama, Esther Hoste, Geert van Loo, Mathieu J M Bertrand
ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway. Science (New York, N.Y.) 378 (6625) (2022)
Geert van Loo, Mathieu J M Bertrand
Death by TNF: a road to inflammation. Nature reviews. Immunology (2022)
Arne Martens, Pieter Hertens, Dario Priem, Vagelis Rinotas, Theodore Meletakos, Meropi Gennadi, Lisette Van Hove, Els Louagie, Julie Coudenys, Amélie De Muynck, Djoere Gaublomme, Mozes Sze, Jolanda van Hengel, Leen Catrysse, Esther Hoste, Jeffrey D Zajac, Rachel A Davey, Luc Van Hoorebeke, Tino Hochepied, Mathieu J M Bertrand, Marietta Armaka, Dirk Elewaut, Geert van Loo
A20 controls RANK-dependent osteoclast formation and bone physiology. EMBO reports 23 (12) (2022)
Lisette Van Hove, Kim Lecomte, Jana Roels, Niels Vandamme, Hanna-Kaisa Vikkula, Isabelle Hoorens, Katia Ongenae, Tino Hochepied, Giacomo Donati, Yvan Saeys, Sven R Quist, Fiona M Watt, Geert van Loo, Esther Hoste
Fibrotic enzymes modulate wound-induced skin tumorigenesis. EMBO reports 22 (5) (2021)
Christopher J Anderson, Christopher B Medina, Brady J Barron, Laura Karvelyte, Tania Løve Aaes, Irina Lambertz, Justin S A Perry, Parul Mehrotra, Amanda Gonçalves, Kelly Lemeire, Gillian Blancke, Vanessa Andries, Farzaneh Ghazavi, Arne Martens, Geert van Loo, Lars Vereecke, Peter Vandenabeele, Kodi S Ravichandran
Microbes exploit death-induced nutrient release by gut epithelial cells. Nature 596 (7871) (2021)
Esther Hoste, Kim Lecomte, Karl Annusver, Niels Vandamme, Jana Roels, Sophia Maschalidi, Lien Verboom, Hanna-Kaisa Vikkula, Mozes Sze, Lisette Van Hove, Kevin Verstaen, Arne Martens, Tino Hochepied, Yvan Saeys, Kodi Ravichandran, Maria Kasper, Geert van Loo
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. Nature communications 12 (1) (2021)
Karolina Slowicka, Ioanna Petta, Gillian Blancke, Esther Hoste, Emilie Dumas, Mozes Sze, Hanna Vikkula, Enrico Radaelli, Jody J Haigh, Sven Jonckheere, Joachim Taminau, Niels Vandamme, Andy Wullaert, Eugene Tulchinsky, David Nittner, Pieter Van Vlierberghe, Gert De Hertogh, Pamela Baldin, Hakki Emre Etlioglu, Pratyaksha Wirapati, Louis Boon, Bart N Lambrecht, Chris Callewaert, Sabine Tejpar, Steven Goossens, Geert Berx, Lars Vereecke, Geert van Loo
Zeb2 drives invasive and microbiota-dependent colon carcinoma. Nature cancer 1 (6) (2020)
Marion Picard, Satoru Yonekura, Karolina Slowicka, Ioanna Petta, Conrad Rauber, Bertrand Routy, Corentin Richard, Valerio Iebba, Maryam Tidjani Alou, Sonia Becharef, Pierre Ly, Eugenie Pizzato, Christian H K Lehmann, Lukas Amon, Christophe Klein, Paule Opolon, Ivo Gomperts Boneca, Jean-Yves Scoazec, Antoine Hollebecque, David Malka, François Ghiringhelli, Diana Dudziak, Geert Berx, Lars Vereecke, Geert van Loo, Guido Kroemer, Laurence Zitvogel, Maria Paula Roberti
Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients. Cell death and differentiation 28 (5) (2020)
Arne Martens, Dario Priem, Esther Hoste, Jessica Vetters, Sofie Rennen, Leen Catrysse, Sofie Voet, Laura Deelen, Mozes Sze, Hanna Vikkula, Karolina Slowicka, Tino Hochepied, Kalliopi Iliaki, Andy Wullaert, Sophie Janssens, Mohamed Lamkanfi, Rudi Beyaert, Marietta Armaka, Mathieu J M Bertrand, Geert van Loo
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities. Nature immunology 21 (4) (2020)
Dario Priem, Michael Devos, Sarah Druw, Arne Martens, Karolina Slowicka, Adrian T Ting, Manolis Pasparakis, Wim Declercq, Peter Vandenabeele, Geert van Loo, Mathieu J M Bertrand
Correction: A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell death & disease 11 (1) (2020)
Arne Martens, Geert van Loo
A20 phosphorylation controls A20 function. Nature immunology 20 (10) (2020)
Sofie Voet, Sahana Srinivasan, Mohamed Lamkanfi, Geert van Loo
Inflammasomes in neuroinflammatory and neurodegenerative diseases. EMBO molecular medicine 11 (6) (2020)
Dario Priem, Michael Devos, Sarah Druwé, Arne Martens, Karolina Slowicka, Adrian T Ting, Manolis Pasparakis, Wim Declercq, Peter Vandenabeele, Geert van Loo, Mathieu J M Bertrand
A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell death & disease 10 (10) (2019)
Karolina Slowicka, Inmaculada Serramito-Gómez, Emilio Boada-Romero, Arne Martens, Mozes Sze, Ioanna Petta, Hanna K Vikkula, Riet De Rycke, Eef Parthoens, Saskia Lippens, Savvas N Savvides, Andy Wullaert, Lars Vereecke, Felipe X Pimentel-Muiños, Geert van Loo
Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature communications 10 (1) (2019)
Inmaculada Serramito-Gómez, Emilio Boada Romero, Karolina Slowicka, Lars Vereecke, Geert van Loo, Felipe X Pimentel-Muiños
The anti-inflammatory protein TNFAIP3/A20 binds the WD40 domain of ATG16L1 to control the autophagic response, NFKB/NF-κB activation and intestinal homeostasis. Autophagy 15 (9) (2019)
Apostolos Polykratis, Arne Martens, Remzi Onur Eren, Yoshitaka Shirasaki, Mai Yamagishi, Yoshifumi Yamaguchi, Sotaro Uemura, Masayuki Miura, Bernhard Holzmann, George Kollias, Marietta Armaka, Geert van Loo, Manolis Pasparakis
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nature cell biology 21 (6) (2019)
Jessica Vetters, Mary J van Helden, Sigrid Wahlen, Simon J Tavernier, Arne Martens, Farzaneh Fayazpour, Karl Vergote, Manon Vanheerswynghels, Kim Deswarte, Justine Van Moorleghem, Sofie De Prijck, Nozomi Takahashi, Peter Vandenabeele, Louis Boon, Geert van Loo, Éric Vivier, Bart N Lambrecht, Sophie Janssens
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF. The Journal of experimental medicine 216 (9) (2019)
Hanne Dubois, Frédéric Sorgeloos, Soroush T Sarvestani, Liesbet Martens, Yvan Saeys, Jason M Mackenzie, Mohamed Lamkanfi, Geert van Loo, Ian Goodfellow, Andy Wullaert
Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection. PLoS pathogens 15 (4) (2019)
Iryna Voytyuk, Stephan A Mueller, Julia Herber, An Snellinx, Dieder Moechars, Geert van Loo, Stefan F Lichtenthaler, Bart De Strooper
BACE2 distribution in major brain cell types and identification of novel substrates. Life science alliance 1 (1) (2018)
Julius Clemens Fischer, Vera Otten, Maike Kober, Christoph Drees, Marc Rosenbaum, Martina Schmickl, Simon Heidegger, Rudi Beyaert, Geert van Loo, Xian Chang Li, Christian Peschel, Marc Schmidt-Supprian, Tobias Haas, Silvia Spoerl, Hendrik Poeck
A20 Restrains Thymic Regulatory T Cell Development. Journal of immunology (Baltimore, Md. : 1950) 199 (7) (2017)
Michael B Drennan, Srinath Govindarajan, Eveline Verheugen, Jonathan M Coquet, Jens Staal, Conor McGuire, Tom Taghon, Georges Leclerq, Rudi Beyaert, Geert van Loo, Bart N Lambrecht, Dirk Elewaut
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20. The Journal of experimental medicine 213 (10) (2016)