Guanghong Wei (Gaunghong Wei)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 62

Top Topics

Carbon Nanotubes

Cerebrospinal Fluid

Amyotrophic Lateral Sclerosis

Top Venues

ACS chemical neuroscience

Physical chemistry chemical physics : PCCP

The journal of physical chemistry. B

This page only lists publications with an associated author ORCID identifier.

Publications

Qin Qiao, Guanghong Wei, Zhijian Song
Structural diversity in the membrane-bound hIAPP dimer correlated with distinct membrane disruption mechanisms. Physical chemistry chemical physics : PCCP 26 (8) (2024)
Zenghui Lao, Yiming Tang, Xuewei Dong, Yuan Tan, Xuhua Li, Xianshi Liu, Le Li, Cong Guo, Guanghong Wei
Elucidating the reversible and irreversible self-assembly mechanisms of low-complexity aromatic-rich kinked peptides and steric zipper peptides. Nanoscale 16 (8) (2024)
Qin Qiao, Guanghong Wei, Zhijian Song
Structural diversity in the membrane-bound hIAPP dimer correlated with distinct membrane disruption mechanisms. Physical chemistry chemical physics : PCCP (2024)
Zenghui Lao, Yiming Tang, Xuewei Dong, Yuan Tan, Xuhua Li, Xianshi Liu, Le Li, Cong Guo, Guanghong Wei
Elucidating the reversible and irreversible self-assembly mechanisms of low-complexity aromatic-rich kinked peptides and steric zipper peptides. Nanoscale (2024)
Qin Qiao, Guanghong Wei, Zhijian Song
Structural diversity in the membrane-bound hIAPP dimer correlated with distinct membrane disruption mechanisms. Physical chemistry chemical physics : PCCP 26 (8) (2024)
Yawei Yu, Qian Liu, Jiyuan Zeng, Yuan Tan, Yiming Tang, Guanghong Wei
Multiscale simulations reveal the driving forces of p53C phase separation accelerated by oncogenic mutations. Chemical science 15 (32) (2024)
Qian Liu, Yawei Yu, Guanghong Wei
Oncogenic R248W mutation induced conformational perturbation of the p53 core domain and the structural protection by proteomimetic amyloid inhibitor ADH-6. Physical chemistry chemical physics : PCCP 26 (29) (2024)
Zenghui Lao, Yiming Tang, Xuewei Dong, Yuan Tan, Xuhua Li, Xianshi Liu, Le Li, Cong Guo, Guanghong Wei
Elucidating the reversible and irreversible self-assembly mechanisms of low-complexity aromatic-rich kinked peptides and steric zipper peptides. Nanoscale 16 (8) (2024)
Qian Liu, Yawei Yu, Guanghong Wei
Oncogenic R248W mutation induced conformational perturbation of the p53 core domain and the structural protection by proteomimetic amyloid inhibitor ADH-6. Physical chemistry chemical physics : PCCP (2024)
Yawei Yu, Qian Liu, Jiyuan Zeng, Yuan Tan, Yiming Tang, Guanghong Wei
Multiscale simulations reveal the driving forces of p53C phase separation accelerated by oncogenic mutations. Chemical science 15 (32) (2024)
Jiaqian Wan, Yu Zou, Ruiqing Sun, Zhengdong Xu, Jiaxing Tang, Yehong Gong, Guanghong Wei, Qingwen Zhang
Destabilization mechanism of R3-R4 tau protofilament by purpurin: a molecular dynamics study. Physical chemistry chemical physics : PCCP (2023)
Dongdong Lin, Zhenyu Qian, Massimo Bagnani, Miguel A Hernández-Rodríguez, Julio Corredoira-Vázquez, Guanghong Wei, Luis Dias Carlos, Raffaele Mezzenga
Probing the Protein Folding Energy Landscape: Dissociation of Amyloid-β Fibrils by Laser-Induced Plasmonic Heating. ACS nano (2023)
Yun Zhou, Yifei Yao, Zhongyuan Yang, Yiming Tang, Guanghong Wei
Naphthoquinone-dopamine hybrids disrupt α-synuclein fibrils by their intramolecular synergistic interactions with fibrils and display a better effect on fibril disruption. Physical chemistry chemical physics : PCCP (2023)
Jiaxing Tang, Yu Zou, Yehong Gong, Zhengdong Xu, Jiaqian Wan, Guanghong Wei, Qingwen Zhang
Molecular Mechanism in the Disruption of Chronic Traumatic Encephalopathy-Related R3-R4 Tau Protofibril by Quercetin and Gallic Acid: Similarities and Differences. ACS chemical neuroscience 14 (5) (2023)
Xuhua Li, Zhiwei Yang, Yujie Chen, Shengli Zhang, Guanghong Wei, Lei Zhang
Dissecting the Molecular Mechanisms of the Co-Aggregation of Aβ40 and Aβ42 Peptides: A REMD Simulation Study. The journal of physical chemistry. B 127 (18) (2023)
Jiaxing Tang, Yu Zou, Yehong Gong, Zhengdong Xu, Jiaqian Wan, Guanghong Wei, Qingwen Zhang
Molecular Mechanism in the Disruption of Chronic Traumatic Encephalopathy-Related R3-R4 Tau Protofibril by Quercetin and Gallic Acid: Similarities and Differences. ACS chemical neuroscience (2023)
Xuhua Li, Zhiwei Yang, Yujie Chen, Shengli Zhang, Guanghong Wei, Lei Zhang
Dissecting the Molecular Mechanisms of the Co-Aggregation of Aβ40 and Aβ42 Peptides: A REMD Simulation Study. The journal of physical chemistry. B (2023)
Qian Liu, Le Li, Yawei Yu, Guanghong Wei
Elucidating the Mechanisms of R248Q Mutation-Enhanced p53 Aggregation and Its Inhibition by Resveratrol. The journal of physical chemistry. B (2023)
Jiyuan Zeng, Yiming Tang, Xuewei Dong, Fangying Li, Guanghong Wei
Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43 321-340 peptide monomer and dimer. Proteins (2023)
Dongdong Lin, Zhenyu Qian, Massimo Bagnani, Miguel A Hernández-Rodríguez, Julio Corredoira-Vázquez, Guanghong Wei, Luis Dias Carlos, Raffaele Mezzenga
Probing the Protein Folding Energy Landscape: Dissociation of Amyloid-β Fibrils by Laser-Induced Plasmonic Heating. ACS nano 17 (10) (2023)
Jiaxing Tang, Yu Zou, Yehong Gong, Zhengdong Xu, Jiaqian Wan, Guanghong Wei, Qingwen Zhang
Molecular Mechanism in the Disruption of Chronic Traumatic Encephalopathy-Related R3-R4 Tau Protofibril by Quercetin and Gallic Acid: Similarities and Differences. ACS chemical neuroscience 14 (5) (2023)
Jiaxing Tang, Yu Zou, Yehong Gong, Zhengdong Xu, Jiaqian Wan, Guanghong Wei, Qingwen Zhang
Molecular Mechanism in the Disruption of Chronic Traumatic Encephalopathy-Related R3-R4 Tau Protofibril by Quercetin and Gallic Acid: Similarities and Differences. ACS chemical neuroscience 14 (5) (2023)
Jiaxing Tang, Yu Zou, Yehong Gong, Zhengdong Xu, Jiaqian Wan, Guanghong Wei, Qingwen Zhang
Molecular Mechanism in the Disruption of Chronic Traumatic Encephalopathy-Related R3-R4 Tau Protofibril by Quercetin and Gallic Acid: Similarities and Differences. ACS chemical neuroscience 14 (5) (2023)
Xianshi Liu, Xuhua Li, Qin Qiao, Fangying Li, Guanghong Wei
ALS-Linked A315T and A315E Mutations Enhance β-Barrel Formation of the TDP-43 307-319 Hexamer: A REST2 Simulation Study. ACS chemical neuroscience (2023)
Fangying Li, Yujie Chen, Yiming Tang, Xianshi Liu, Guanghong Wei
Dissecting the Effect of ALS Mutation G335D on the Early Aggregation of the TDP-43 Amyloidogenic Core Peptide: Helix-to-β-Sheet Transition and Conformational Shift. Journal of chemical information and modeling (2023)
Xuhua Li, Zhiwei Yang, Yujie Chen, Shengli Zhang, Guanghong Wei, Lei Zhang
Dissecting the Molecular Mechanisms of the Co-Aggregation of Aβ40 and Aβ42 Peptides: A REMD Simulation Study. The journal of physical chemistry. B 127 (18) (2023)
Jiyuan Zeng, Yiming Tang, Xuewei Dong, Fangying Li, Guanghong Wei
Influence of ALS-linked M337V mutation on the conformational ensembles of TDP-43 321-340 peptide monomer and dimer. Proteins (2023)
Yuying Liu, Ying Wang, Chaohui Tong, Guanghong Wei, Feng Ding, Yunxiang Sun
Molecular Insights into the Self-Assembly of Block Copolymer Suckerin Polypeptides into Nanoconfined β-Sheets. Small (Weinheim an der Bergstrasse, Germany) 18 (34) (2022)
Yuying Liu, Ying Wang, Yu Zhang, Yu Zou, Guanghong Wei, Feng Ding, Yunxiang Sun
Structural Perturbation of Monomers Determines the Amyloid Aggregation Propensity of Calcitonin Variants. Journal of chemical information and modeling (2022)
Zhengdong Xu, Yehong Gong, Yu Zou, Jiaqian Wan, Jiaxing Tang, Chendi Zhan, Guanghong Wei, Qingwen Zhang
Dissecting the Inhibitory Mechanism of the αB-Crystallin Domain against Aβ 42 Aggregation and Its Effect on Aβ 42 Protofibrils: A Molecular Dynamics Simulation Study. ACS chemical neuroscience 13 (19) (2022)
Yu Zhang, Ying Wang, Yuying Liu, Guanghong Wei, Feng Ding, Yunxiang Sun
Molecular Insights into the Misfolding and Dimerization Dynamics of the Full-Length α-Synuclein from Atomistic Discrete Molecular Dynamics Simulations. ACS chemical neuroscience 13 (21) (2022)
Xianshi Liu, Zenghui Lao, Xuhua Li, Xuewei Dong, Guanghong Wei
ALS-associated A315E and A315pT variants exhibit distinct mechanisms in inducing irreversible aggregation of TDP-43 312-317 peptides. Physical chemistry chemical physics : PCCP 24 (26) (2022)
Jiaming Guan, Zhijian Song, Guanghong Wei, Qin Qiao
Distinct binding interactions trigger opposite conformational modulations on pathogenic and wildtype Huntingtin exon 1 proteins. Physical chemistry chemical physics : PCCP 24 (40) (2022)
Zenghui Lao, Xuewei Dong, Xianshi Liu, Fangying Li, Yujie Chen, Yiming Tang, Guanghong Wei
Insights into the Atomistic Mechanisms of Phosphorylation in Disrupting Liquid-Liquid Phase Separation and Aggregation of the FUS Low-Complexity Domain. Journal of chemical information and modeling 62 (13) (2022)
Duo Gao, Jiaqian Wan, Yu Zou, Yehong Gong, Xuewei Dong, Zhengdong Xu, Jiaxing Tang, Guanghong Wei, Qingwen Zhang
The destructive mechanism of Aβ 1-42 protofibrils by norepinephrine revealed via molecular dynamics simulations. Physical chemistry chemical physics : PCCP 24 (33) (2022)
Yawei Yu, Xuewei Dong, Yiming Tang, Le Li, Guanghong Wei
Mechanistic insight into the destabilization of p53TD tetramer by cancer-related R337H mutation: a molecular dynamics study. Physical chemistry chemical physics : PCCP 24 (8) (2022)
Ying Wang, Yuying Liu, Yu Zhang, Guanghong Wei, Feng Ding, Yunxiang Sun
Molecular insights into the oligomerization dynamics and conformations of amyloidogenic and non-amyloidogenic amylin from discrete molecular dynamics simulations. Physical chemistry chemical physics : PCCP 24 (36) (2022)
Fangying Li, Yujie Chen, Xianshi Liu, Yiming Tang, Xuewei Dong, Guanghong Wei
Atomistic Insights into A315E Mutation-Enhanced Pathogenicity of TDP-43 Core Fibrils. ACS chemical neuroscience 13 (18) (2022)
Chendi Zhan, Zenghui Lao, Yiming Tang, Qin Qiao, Guanghong Wei
Natural stereoisomeric flavonoids exhibit different disruptive effects and the mechanism of action on Aβ42 protofibril. Chemical communications (Cambridge, England) 57 (35) (2021)
Xuewei Dong, Santu Bera, Qin Qiao, Yiming Tang, Zenghui Lao, Yin Luo, Ehud Gazit, Guanghong Wei
Liquid-Liquid Phase Separation of Tau Protein Is Encoded at the Monomeric Level. The journal of physical chemistry letters 12 (10) (2021)
Yiming Tang, Yifei Yao, Guanghong Wei
Unraveling the Allosteric Mechanism of Four Cancer-related Mutations in the Disruption of p53-DNA Interaction. The journal of physical chemistry. B 125 (36) (2021)
Wei Ji, Yiming Tang, Pandeeswar Makam, Yifei Yao, Ranran Jiao, Kaiyong Cai, Guanghong Wei, Ehud Gazit
Expanding the Structural Diversity and Functional Scope of Diphenylalanine-Based Peptide Architectures by Hierarchical Coassembly. Journal of the American Chemical Society 143 (42) (2021)
Xuewei Dong, Ruxi Qi, Qin Qiao, Xuhua Li, Fangying Li, Jiaqian Wan, Qingwen Zhang, Guanghong Wei
Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations. Physical chemistry chemical physics : PCCP 23 (36) (2021)
Phuong Hoang Nguyen, Ayyalusamy Ramamoorthy, Bikash R Sahoo, Jie Zheng, Peter Faller, John E Straub, Laura Domínguez, Joan-Emma Shea, Nikolay V Dokholyan, Alfonso De Simone, Buyong Ma, Ruth Nussinov, Saeed Najafi, Son Tung Ngo, Antoine Loquet, Mara Chiricotto, Pritam Ganguly, James J McCarty, Mai Suan Li, Carol K Hall, Yiming Wang, Yifat Miller, Simone Melchionna, Birgit Habenstein, Stepan Timr, Jiaxing Chen, Brianna Hnath, Birgit Strodel, Rakez Kayed, Sylvain Lesné, Guanghong Wei, Fabio Sterpone, Andrew J Doig, Philippe Derreumaux
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis. Chemical reviews 121 (4) (2021)
Yehong Gong, Chendi Zhan, Yu Zou, Zhenyu Qian, Guanghong Wei, Qingwen Zhang
Serotonin and Melatonin Show Different Modes of Action on Aβ42 Protofibril Destabilization. ACS chemical neuroscience 12 (4) (2021)
Yujie Chen, Xuhua Li, Chendi Zhan, Zenghui Lao, Fangying Li, Xuewei Dong, Guanghong Wei
A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation. ACS chemical neuroscience 12 (21) (2021)
Xuhua Li, Zenghui Lao, Yu Zou, Xuewei Dong, Le Li, Guanghong Wei
Mechanistic Insights into the Co-Aggregation of Aβ and hIAPP: An All-Atom Molecular Dynamic Study. The journal of physical chemistry. B 125 (8) (2021)
Yifei Yao, Yiming Tang, Guanghong Wei
Epigallocatechin Gallate Destabilizes α-Synuclein Fibril by Disrupting the E46-K80 Salt-Bridge and Inter-protofibril Interface. ACS chemical neuroscience 11 (24) (2020)
Dongdong Lin, Jiangtao Lei, Shujie Li, Xingfei Zhou, Guanghong Wei, Xinju Yang
Investigation of the Dissociation Mechanism of Single-Walled Carbon Nanotube on Mature Amyloid-β Fibrils at Single Nanotube Level. The journal of physical chemistry. B 124 (17) (2020)
Chendi Zhan, Yujie Chen, Yiming Tang, Guanghong Wei
Green Tea Extracts EGCG and EGC Display Distinct Mechanisms in Disrupting Aβ42 Protofibril. ACS chemical neuroscience 11 (12) (2020)
Yujie Chen, Guanghong Wei, Jun Zhao, Ruth Nussinov, Buyong Ma
Computational Investigation of Gantenerumab and Crenezumab Recognition of Aβ Fibrils in Alzheimer's Disease Brain Tissue. ACS chemical neuroscience 11 (20) (2020)
Yiming Tang, Yifei Yao, Guanghong Wei
Expanding the structural diversity of peptide assemblies by coassembling dipeptides with diphenylalanine. Nanoscale 12 (5) (2020)
Hongqing Wang, Qian Xu, Zhihua Liu, Yiming Tang, Guanghong Wei, Y Ron Shen, Wei-Tao Liu
Gate-Controlled Sum-Frequency Vibrational Spectroscopy for Probing Charged Oxide/Water Interfaces. The journal of physical chemistry letters 10 (19) (2019)
Santu Bera, Sudipta Mondal, Yiming Tang, Guy Jacoby, Elad Arad, Tom Guterman, Raz Jelinek, Roy Beck, Guanghong Wei, Ehud Gazit
Deciphering the Rules for Amino Acid Co-Assembly Based on Interlayer Distances. ACS nano 13 (2) (2019)
Xuhua Li, Jiangtao Lei, Ruxi Qi, Luogang Xie, Guanghong Wei
Mechanistic insight into E22Q-mutation-induced antiparallel-to-parallel β-sheet transition of Aβ16-22 fibrils: an all-atom simulation study. Physical chemistry chemical physics : PCCP 21 (28) (2019)
Yu Zou, Zhenyu Qian, Yujie Chen, Hongsheng Qian, Guanghong Wei, Qingwen Zhang
Norepinephrine Inhibits Alzheimer's Amyloid-β Peptide Aggregation and Destabilizes Amyloid-β Protofibrils: A Molecular Dynamics Simulation Study. ACS chemical neuroscience 10 (3) (2019)
Zenghui Lao, Yujie Chen, Yiming Tang, Guanghong Wei
Molecular Dynamics Simulations Reveal the Inhibitory Mechanism of Dopamine against Human Islet Amyloid Polypeptide (hIAPP) Aggregation and Its Destabilization Effect on hIAPP Protofibrils. ACS chemical neuroscience 10 (9) (2019)
Yibo Jin, Yunxiang Sun, Yujie Chen, Jiangtao Lei, Guanghong Wei
Molecular dynamics simulations reveal the mechanism of graphene oxide nanosheet inhibition of Aβ1-42 peptide aggregation. Physical chemistry chemical physics : PCCP 21 (21) (2019)
Yuxiang Mo, Sayanti Brahmachari, Jiangtao Lei, Sharon Gilead, Yiming Tang, Ehud Gazit, Guanghong Wei
The Inhibitory Effect of Hydroxylated Carbon Nanotubes on the Aggregation of Human Islet Amyloid Polypeptide Revealed by a Combined Computational and Experimental Study. ACS chemical neuroscience 9 (11) (2018)
Hilary A Weismiller, Rachel Murphy, Guanghong Wei, Buyong Ma, Ruth Nussinov, Martin Margittai
Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms. The Journal of biological chemistry 293 (45) (2018)
Noam Brown, Jiangtao Lei, Chendi Zhan, Linda J W Shimon, Lihi Adler-Abramovich, Guanghong Wei, Ehud Gazit
Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System. ACS nano 12 (4) (2018)
William M Hewitt, George T Lountos, Katherine Zlotkowski, Samuel D Dahlhauser, Lindsey B Saunders, Danielle Needle, Joseph E Tropea, Chendi Zhan, Guanghong Wei, Buyong Ma, Ruth Nussinov, David S Waugh, John S Schneekloth
Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angewandte Chemie (International ed. in English) 55 (19) (2016)