John S Schneekloth (John Schneekloth)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 33

Top Venues

Angewandte Chemie (International ed. in English)

ACS chemical biology

Nature communications

bioRxiv : the preprint server for biology

National Cancer Institute

Yale University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National Cancer Institute Aug 01 2011

United States

Investigator :: Chemical Biology Laboratory

Education History

Yale University Sep 01 2001 - Jun 01 2006

United States

PHD :: Chemistry

Publications

Shaifaly Parmar, Desta Doro Bume, Colleen M Connelly, Robert Boer, Peri R Prestwood, Zhen Wang, Henning Labuhn, Krishshanthi Sinnadurai, Adeline Feri, Jimmy Ouellet, Philip Homan, Tomoyuki Numata, John S Schneekloth
Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression. bioRxiv : the preprint server for biology (2024)
Shaifaly Parmar, Desta Doro Bume, Colleen M Connelly, Robert E Boer, Peri R Prestwood, Zhen Wang, Henning Labuhn, Krishshanthi Sinnadurai, Adeline Feri, Jimmy Ouellet, Philip Homan, Tomoyuki Numata, John S Schneekloth
Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression. Nature communications 15 (1) (2024)
John S Schneekloth, Mo Yang, Peri Prestwood, Luiz Passalacqua, Sumirtha Balaratnam, Christopher Fullenkamp, Winston Arney, Kevin M Weeks, Adrian Ferre-D'Amare
Structure-Informed Design of an Ultra Bright RNA-activated Fluorophore. Research square (2024)
Peri R Prestwood, Mo Yang, Grace V Lewis, Sumirtha Balaratnam, Kamyar Yazdani, John S Schneekloth
Competitive Microarray Screening Reveals Functional Ligands for the DHX15 RNA G-Quadruplex. ACS medicinal chemistry letters 15 (6) (2024)
Peri R Prestwood, Mo Yang, Grace V Lewis, Sumirtha Balaratnam, Kamyar Yazdani, John S Schneekloth
Competitive Microarray Screening Reveals Functional Ligands for the DHX15 RNA G-Quadruplex. ACS medicinal chemistry letters 15 (6) (2024)
Shaifaly Parmar, Desta Doro Bume, Colleen M Connelly, Robert Boer, Peri R Prestwood, Zhen Wang, Henning Labuhn, Krishshanthi Sinnadurai, Adeline Feri, Jimmy Ouellet, Philip Homan, Tomoyuki Numata, John S Schneekloth
Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression. bioRxiv : the preprint server for biology (2024)
John S Schneekloth, Mo Yang, Peri Prestwood, Luiz Passalacqua, Sumirtha Balaratnam, Christopher Fullenkamp, Winston Arney, Kevin M Weeks, Adrian Ferre-D'Amare
Structure-Informed Design of an Ultra Bright RNA-activated Fluorophore. Research square (2024)
Christopher R Fullenkamp, John S Schneekloth
RNA as an off-target for FDA-approved drugs. Nature chemistry (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) 62 (11) (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) 62 (11) (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) 62 (11) (2023)
Kamyar Yazdani, Srinath Seshadri, Desiree Tilo, Mo Yang, Christopher D Sibley, Charles Vinson, John S Schneekloth
Decoding complexity in biomolecular recognition of DNA i-motifs with microarrays. Nucleic acids research (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) 62 (11) (2023)
Mo Yang, Feyisola P Olatunji, Curran Rhodes, Sumirtha Balaratnam, Kara Dunne-Dombrink, Srinath Seshadri, Xiao Liang, Christopher P Jones, Stuart F J Le Grice, Adrian R Ferré-D'Amaré, John S Schneekloth
Discovery of Small Molecules Targeting the Frameshifting Element RNA in SARS-CoV-2 Viral Genome. ACS medicinal chemistry letters 14 (6) (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) 62 (11) (2023)
Kamyar Yazdani, Srinath Seshadri, Desiree Tillo, Charles Vinson, John S Schneekloth
DECODING COMPLEXITY IN BIOMOLECULAR RECOGNITION OF DNA I-MOTIFS. bioRxiv : the preprint server for biology (2023)
Kamyar Yazdani, Srinath Seshadri, Desiree Tillo, Charles Vinson, John S Schneekloth
DECODING COMPLEXITY IN BIOMOLECULAR RECOGNITION OF DNA I-MOTIFS. bioRxiv : the preprint server for biology (2023)
Kamyar Yazdani, Deondre Jordan, Mo Yang, Christopher R Fullenkamp, David R Calabrese, Robert Boer, Thomas Hilimire, Timothy E H Allen, Rabia T Khan, John S Schneekloth
Machine Learning Informs RNA-Binding Chemical Space. Angewandte Chemie (International ed. in English) (2022)
Sumirtha Balaratnam, Curran Rhodes, Desta Doro Bume, Colleen M Connelly, Christopher C Lai, James A Kelley, Kamyar Yazdani, Philip J Homan, Danny Incarnato, Tomoyuki Numata, John S Schneekloth
A chemical probe based on the PreQ1 metabolite enables transcriptome-wide mapping of binding sites. Nature communications 12 (1) (2021)
Monalisa Swain, Abeer A Ageeli, Wojciech K Kasprzak, Mi Li, Jennifer T Miller, Joanna Sztuba-Solinska, John S Schneekloth, Deepak Koirala, Joseph Piccirili, Americo J Fraboni, Ryan P Murelli, Alexander Wlodawer, Bruce A Shapiro, Nathan J Baird, Stuart F J Le Grice
Dynamic bulge nucleotides in the KSHV PAN ENE triple helix provide a unique binding platform for small molecule ligands. Nucleic acids research (2021)
Xue Zhi Zhao, Evgeny Kiselev, George T Lountos, Wenjie Wang, Joseph E Tropea, Danielle Needle, Thomas A Hilimire, John S Schneekloth, David S Waugh, Yves Pommier, Terrence R Burke
Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites. Chemical science 12 (11) (2021)
Sreejana Ray, Desiree Tilo, Robert E Boer, Nima Assad, Mira Barshai, Guanhui Wu, Yaron Orenstein, Danzhou Yang, John S Schneekloth, Charles Vinson
Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes. ACS chemical biology 15 (4) (2020)
Robert E Boer, Zachary R Torrey, John S Schneekloth
Chemical Modulation of Pre-mRNA Splicing in Mammalian Systems. ACS chemical biology 15 (4) (2020)
Colleen M Connelly, Tomoyuki Numata, Robert E Boer, Michelle H Moon, Ranu S Sinniah, Joseph J Barchi, Adrian R Ferre-D'Amare, John S Schneekloth
Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nature communications 10 (1) (2019)
Fardokht A Abulwerdi, Wenbo Xu, Abeer A Ageeli, Michael J Yonkunas, Gayatri Arun, Hyeyeon Nam, John S Schneekloth, Theodore Kwaku Dayie, David Spector, Nathan J Baird, Stuart F J Le Grice
Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1. ACS chemical biology 14 (2) (2019)
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski, John K Simmons, Lindsey B Saunders, Shuling Zhang, Daniel Connors, Kylie J Walters, Beverly A Mock, John S Schneekloth
Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex. Nature communications 9 (1) (2018)
Michelle H Moon, Thomas A Hilimire, Allix M Sanders, John S Schneekloth
Measuring RNA-Ligand Interactions with Microscale Thermophoresis. Biochemistry 57 (31) (2018)
Sara N Journey, Stephanie L Alden, Will M Hewitt, Megan L Peach, Marc C Nicklaus, John S Schneekloth
Probing the hras-1Y i-motif with small molecules. MedChemComm 9 (12) (2018)
Pengcheng Yan, Daniel A Ritt, Katherine Zlotkowski, Heidi R Bokesch, William C Reinhold, John S Schneekloth, Deborah K Morrison, Kirk R Gustafson
Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling. Journal of natural products 81 (7) (2018)
Katherine Zlotkowski, William M Hewitt, Pengcheng Yan, Heidi R Bokesch, Megan L Peach, Marc C Nicklaus, Barry R O'Keefe, James B McMahon, Kirk R Gustafson, John S Schneekloth
Macrophilone A: Structure Elucidation, Total Synthesis, and Functional Evaluation of a Biologically Active Iminoquinone from the Marine Hydroid Macrorhynchia philippina. Organic letters 19 (7) (2017)
Colleen M Connelly, Robert E Boer, Michelle H Moon, Peter Gareiss, John S Schneekloth
Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays. ACS chemical biology 12 (2) (2016)
William M Hewitt, George T Lountos, Katherine Zlotkowski, Samuel D Dahlhauser, Lindsey B Saunders, Danielle Needle, Joseph E Tropea, Chendi Zhan, Guanghong Wei, Buyong Ma, Ruth Nussinov, David S Waugh, John S Schneekloth
Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Angewandte Chemie (International ed. in English) 55 (19) (2016)
Fardokht A Abulwerdi, Matthew D Shortridge, Joanna Sztuba-Solinska, Robert Wilson, Stuart F J Le Grice, Gabriele Varani, John S Schneekloth
Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA. Journal of medicinal chemistry 59 (24) (2016)

John S Schneekloth.css-eqlu8i{font-size:small;padding-left:4px;} (John Schneekloth)

Publication Activity (10 Years)

Top Topics

Top Venues

John S Schneekloth (John Schneekloth)